| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Koichi Kozak. [Current concepts of vascular calcification]. Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics. vol 42. issue 6. 2006-01-31. PMID:16408509. |
besides apoptosis and pi uptake, such proteins as osteoprotegerin (opg), matrix gla protein (mgp), klotho, fetuin-a, and apoe have been shown to negatively affect vascular calcification. |
2006-01-31 |
2023-08-12 |
human |
| Bindu Menon, Mahipal Singh, Robert S Ross, Jennifer N Johnson, Krishna Sing. beta-Adrenergic receptor-stimulated apoptosis in adult cardiac myocytes involves MMP-2-mediated disruption of beta1 integrin signaling and mitochondrial pathway. American journal of physiology. Cell physiology. vol 290. issue 1. 2006-01-27. PMID:16148033. |
recently, we have shown that inhibition of matrix metalloproteinase-2 (mmp-2) inhibits beta-ar-stimulated apoptosis and that the apoptotic effects of mmp-2 are possibly mediated via its interaction with beta1 integrins. |
2006-01-27 |
2023-08-12 |
human |
| Jeremy S Duffield, Peter G Tipping, Tiina Kipari, Jean-François Cailhier, Spike Clay, Richard Lang, Joseph V Bonventre, Jeremy Hughe. Conditional ablation of macrophages halts progression of crescentic glomerulonephritis. The American journal of pathology. vol 167. issue 5. 2006-01-26. PMID:16251406. |
in the presence of macrophages, interstitial myofibroblasts exhibited increased levels of both proliferation and apoptosis, suggesting that macrophages act to support a population of renal myofibroblasts in a high turnover state and in matrix deposition. |
2006-01-26 |
2023-08-12 |
mouse |
| Katja Breitkopf, Stephan Haas, Eliza Wiercinska, Manfred V Singer, Steven Doole. Anti-TGF-beta strategies for the treatment of chronic liver disease. Alcoholism, clinical and experimental research. vol 29. issue 11 Suppl. 2006-01-26. PMID:16344596. |
in parallel, tgf-beta triggers hepatocytes that are strongly responsive for this cytokine, to undergo apoptosis, thereby providing space for hsc proliferation and generation of a collagenous matrix. |
2006-01-26 |
2023-08-12 |
human |
| Viktor Todorovic, Chih-Chiun Chen, Nissim Hay, Lester F La. The matrix protein CCN1 (CYR61) induces apoptosis in fibroblasts. The Journal of cell biology. vol 171. issue 3. 2006-01-24. PMID:16275757. |
the matrix protein ccn1 (cyr61) induces apoptosis in fibroblasts. |
2006-01-24 |
2023-08-12 |
Not clear |
| Viktor Todorovic, Chih-Chiun Chen, Nissim Hay, Lester F La. The matrix protein CCN1 (CYR61) induces apoptosis in fibroblasts. The Journal of cell biology. vol 171. issue 3. 2006-01-24. PMID:16275757. |
contrary to this paradigm, we show that fibroblast adhesion to the angiogenic matrix protein ccn1 (cyr61) induces apoptosis, whereas endothelial cell adhesion to ccn1 promotes cell survival. |
2006-01-24 |
2023-08-12 |
Not clear |
| Viktor Todorovic, Chih-Chiun Chen, Nissim Hay, Lester F La. The matrix protein CCN1 (CYR61) induces apoptosis in fibroblasts. The Journal of cell biology. vol 171. issue 3. 2006-01-24. PMID:16275757. |
these results show that cellular interaction with a specific matrix protein can either induce or suppress apoptosis in a cell type-specific manner and that integrin alpha6beta1-hspgs can function as receptors to induce p53-dependent apoptosis. |
2006-01-24 |
2023-08-12 |
Not clear |
| Jean-Christophe Copin, Marie-Christelle Goodyear, Jeffrey M Gidday, Aarti R Shah, Eduardo Gascon, Alexandre Dayer, Denis M Morel, Yvan Gasch. Role of matrix metalloproteinases in apoptosis after transient focal cerebral ischemia in rats and mice. The European journal of neuroscience. vol 22. issue 7. 2006-01-23. PMID:16197500. |
role of matrix metalloproteinases in apoptosis after transient focal cerebral ischemia in rats and mice. |
2006-01-23 |
2023-08-12 |
mouse |
| Jean-Christophe Copin, Marie-Christelle Goodyear, Jeffrey M Gidday, Aarti R Shah, Eduardo Gascon, Alexandre Dayer, Denis M Morel, Yvan Gasch. Role of matrix metalloproteinases in apoptosis after transient focal cerebral ischemia in rats and mice. The European journal of neuroscience. vol 22. issue 7. 2006-01-23. PMID:16197500. |
the involvement of matrix metalloproteinases (mmps) in cerebral ischemia-induced apoptosis was investigated in a model of transient focal cerebral ischemia in rats treated intracerebroventricularly (i.c.v.) |
2006-01-23 |
2023-08-12 |
mouse |
| Mehdi Shakibaei, Gundula Schulze-Tanzil, Thilo John, Ali Mobasher. Curcumin protects human chondrocytes from IL-l1beta-induced inhibition of collagen type II and beta1-integrin expression and activation of caspase-3: an immunomorphological study. Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft. vol 187. issue 5-6. 2006-01-23. PMID:16320828. |
at the cellular level, il-1beta activates matrix degrading enzymes, down-regulates expression of matrix components and induces chondrocyte apoptosis. |
2006-01-23 |
2023-08-12 |
human |
| Sergey G Kuznetsov, Thomas C G Bosc. Self/nonself recognition in Cnidaria: contact to allogeneic tissue does not result in elimination of nonself cells in Hydra vulgaris. Zoology (Jena, Germany). vol 106. issue 2. 2006-01-23. PMID:16351896. |
in a previous paper (kuznetsov et al., 2002) we described that cells which accumulate in the contact region of these interspecies grafts are apoptotic and that apoptosis is induced by impaired cell matrix contact. |
2006-01-23 |
2023-08-12 |
Not clear |
| Jérôme Jourquin, Evelyne Tremblay, Anne Bernard, Gérard Charton, Franck A Chaillan, Evelyne Marchetti, François S Roman, Paul D Soloway, Vincent Dive, Athanasios Yiotakis, Michel Khrestchatisky, Santiago River. Tissue inhibitor of metalloproteinases-1 (TIMP-1) modulates neuronal death, axonal plasticity, and learning and memory. The European journal of neuroscience. vol 22. issue 10. 2006-01-17. PMID:16307599. |
the tissue inhibitor of metalloproteinases-1 (timp-1) belongs to a family of multifunctional proteins that inhibit matrix metalloproteinases (mmps), but also regulate cell growth, proliferation, migration and apoptosis in non-nervous tissues. |
2006-01-17 |
2023-08-12 |
mouse |
| Yuki Kishida, Makoto Hirao, Noriyuki Tamai, Akihide Nampei, Tetsuho Fujimoto, Takanobu Nakase, Nobuyuki Shimizu, Hideki Yoshikawa, Akira Myou. Leptin regulates chondrocyte differentiation and matrix maturation during endochondral ossification. Bone. vol 37. issue 5. 2006-01-12. PMID:16039170. |
effects of leptin on chondrocyte gene expression, cell cycle, apoptosis and matrix mineralization were assessed using primary chondrocyte culture and the atdc5 cell differentiation culture system. |
2006-01-12 |
2023-08-12 |
mouse |
| Yuki Kishida, Makoto Hirao, Noriyuki Tamai, Akihide Nampei, Tetsuho Fujimoto, Takanobu Nakase, Nobuyuki Shimizu, Hideki Yoshikawa, Akira Myou. Leptin regulates chondrocyte differentiation and matrix maturation during endochondral ossification. Bone. vol 37. issue 5. 2006-01-12. PMID:16039170. |
during atdc5 cell differentiation culture, exogenous leptin at a concentration of 1-10 ng/ml (equivalent to the normal serum concentration of leptin) altered type x collagen mrna expression and suppressed apoptosis, cell growth and matrix calcification. |
2006-01-12 |
2023-08-12 |
mouse |
| Zaiping Liu, Hongbing Li, Mathieu Derouet, Jorge Filmus, Eric C LaCasse, Robert G Korneluk, Robert S Kerbel, Kirill V Rose. ras Oncogene triggers up-regulation of cIAP2 and XIAP in intestinal epithelial cells: epidermal growth factor receptor-dependent and -independent mechanisms of ras-induced transformation. The Journal of biological chemistry. vol 280. issue 45. 2006-01-12. PMID:16115895. |
detachment of normal epithelial cells from the extracellular matrix (ecm) triggers apoptosis, a phenomenon called anoikis. |
2006-01-12 |
2023-08-12 |
Not clear |
| Jean-Loup Bascands, Joost P Schanstr. Obstructive nephropathy: insights from genetically engineered animals. Kidney international. vol 68. issue 3. 2006-01-11. PMID:16105023. |
this model mimics, in an accelerated manner, the different stages of obstructive nephropathy leading to tubulointerstitial fibrosis: cellular infiltration, tubular proliferation and apoptosis, epithelial-mesenchymal transition (emt), (myo)fibroblast accumulation, increased extracellular matrix (ecm) deposition, and tubular atrophy. |
2006-01-11 |
2023-08-12 |
Not clear |
| Shin-Ichi Manabe, Zezong Gu, Stuart A Lipto. Activation of matrix metalloproteinase-9 via neuronal nitric oxide synthase contributes to NMDA-induced retinal ganglion cell death. Investigative ophthalmology & visual science. vol 46. issue 12. 2006-01-11. PMID:16303975. |
another factor is the abnormal activation of matrix metalloproteinases (mmps), in particular mmp-9, which triggers an extracellular signaling cascade leading to apoptosis. |
2006-01-11 |
2023-08-12 |
Not clear |
| Christopher A Derderian, Nicholas Bastidas, Oren Z Lerman, Kirit A Bhatt, Shin-E Lin, Jeremy Voss, Jeffrey W Holmes, Jamie P Levine, Geoffrey C Gurtne. Mechanical strain alters gene expression in an in vitro model of hypertrophic scarring. Annals of plastic surgery. vol 55. issue 1. 2006-01-10. PMID:15985794. |
these results suggest that mechanical strain up-regulates matrix remodeling genes and down-regulates normal cellular apoptosis, resulting in more cells, each of which produces more matrix. |
2006-01-10 |
2023-08-12 |
Not clear |
| Matthew J Naylor, Na Li, Julia Cheung, Emma T Lowe, Elise Lambert, Rebecca Marlow, Pengbo Wang, Franziska Schatzmann, Timothy Wintermantel, Günther Schüetz, Alan R Clarke, Ulrich Mueller, Nancy E Hynes, Charles H Streul. Ablation of beta1 integrin in mammary epithelium reveals a key role for integrin in glandular morphogenesis and differentiation. The Journal of cell biology. vol 171. issue 4. 2006-01-06. PMID:16301336. |
in vivo, epithelial cells became detached from the extracellular matrix but remained associated with each other and did not undergo overt apoptosis. |
2006-01-06 |
2023-08-12 |
mouse |
| Alexander V Ovechkin, Neetu Tyagi, Walter E Rodriguez, Melvin R Hayden, Karni S Moshal, Suresh C Tyag. Role of matrix metalloproteinase-9 in endothelial apoptosis in chronic heart failure in mice. Journal of applied physiology (Bethesda, Md. : 1985). vol 99. issue 6. 2006-01-05. PMID:16081621. |
role of matrix metalloproteinase-9 in endothelial apoptosis in chronic heart failure in mice. |
2006-01-05 |
2023-08-12 |
mouse |