| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| H Paul Ehrlich, Tammy Die. Role for gap junctional intercellular communications in wound repair. Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society. vol 11. issue 6. 2004-03-26. PMID:14617290. |
the participation of fibroblasts in wound repair is a coordinated effort requiring sequential cellular modulations to behavior including migration (entering), proliferation (increasing cell numbers), synthesis (depositing a collagen matrix), remodeling (organizing collagen), transformation into myofibroblasts, apoptosis, and elimination. |
2004-03-26 |
2023-08-12 |
rat |
| Sam J Wadsworth, Anette M Freyer, Randolph L Corteling, Ian P Hal. Biosynthesized matrix provides a key role for survival signaling in bronchial epithelial cells. American journal of physiology. Lung cellular and molecular physiology. vol 286. issue 3. 2004-03-26. PMID:14617518. |
beas-2b cells secrete their own biosynthesized matrix (bsm), which also provides rescue from apoptosis. |
2004-03-26 |
2023-08-12 |
Not clear |
| Sandra Hodge, Greg Hodge, Raffaele Scicchitano, Paul N Reynolds, Mark Holme. Alveolar macrophages from subjects with chronic obstructive pulmonary disease are deficient in their ability to phagocytose apoptotic airway epithelial cells. Immunology and cell biology. vol 81. issue 4. 2004-03-19. PMID:12848850. |
while chronic inflammation, extracellular matrix destruction and increased airway epithelial cell apoptosis are reported in chronic obstructive pulmonary disease, the understanding of the basic pathogenesis of the disease is limited and there are no effective treatments. |
2004-03-19 |
2023-08-12 |
human |
| Emmanuelle Charafe-Jauffret, François Bertucci, Olivier Ramuz, Elisabeth Devilard, Philippe Gaulard, Pierre Brousset, Remi Houlgatte, J Hassoun, Daniel Birnbaum, Luc Xerr. Characterization of Hodgkin's lymphoma-like undifferentiated carcinoma of the nasopharyngeal type as a particular UCNT subtype mimicking Hodgkin's lymphoma. International journal of oncology. vol 23. issue 1. 2004-03-18. PMID:12792781. |
significant differences were detected in the expression of genes involved in the matrix modelling, angiogenesis, apoptosis and regulation of the th-2 interleukins. |
2004-03-18 |
2023-08-12 |
Not clear |
| Qi Qian, Larry W Hunter, Ming Li, Miguel Marin-Padilla, Y S Prakash, Stefan Somlo, Peter C Harris, Vicente E Torres, Gary C Siec. Pkd2 haploinsufficiency alters intracellular calcium regulation in vascular smooth muscle cells. Human molecular genetics. vol 12. issue 15. 2004-03-16. PMID:12874107. |
based on these findings, and the fact that [ca(2+)](i) signaling is essential to the regulation of contraction, production and secretion of extracellular matrix, cellular proliferation and apoptosis, we propose that the abnormal intracellular ca(2+) regulation associated with pkd2 haploinsufficiency is directly related to the vascular phenotype. |
2004-03-16 |
2023-08-12 |
mouse |
| Verena M Dirsch, Irina M Müller, Sören T Eichhorst, George R Pettit, Yoshiaki Kamano, Masuo Inoue, Jun-Ping Xu, Yoshitatsu Ichihara, Gerhard Wanner, Angelika M Vollma. Cephalostatin 1 selectively triggers the release of Smac/DIABLO and subsequent apoptosis that is characterized by an increased density of the mitochondrial matrix. Cancer research. vol 63. issue 24. 2004-03-11. PMID:14695204. |
cephalostatin 1 selectively triggers the release of smac/diablo and subsequent apoptosis that is characterized by an increased density of the mitochondrial matrix. |
2004-03-11 |
2023-08-12 |
Not clear |
| Reiko Inagi, Masaomi Nangaku, Toshio Miyata, Kiyoshi Kurokaw. Mesangial cell-predominant functional gene, megsin. Clinical and experimental nephrology. vol 7. issue 2. 2004-03-09. PMID:14586725. |
megsin may play a role in the regulation of a wide variety of processes in mesangial cells, such as matrix metabolism, cell proliferation, and apoptosis. |
2004-03-09 |
2023-08-12 |
mouse |
| Sergio Ruiz-Llorente, Jerónimo Bravo, Arancha Cebrián, Alberto Cascón, Marina Pollan, Dolores Tellería, Rocío Letón, Miguel Urioste, Raquel Rodríguez-López, Jose M de Campos, María J Muñoz, Carmen Lacambra, Javier Benítez, Mercedes Robled. Genetic characterization and structural analysis of VHL Spanish families to define genotype-phenotype correlations. Human mutation. vol 23. issue 2. 2004-03-08. PMID:14722919. |
this gene, located in the 3p25-26 chromosome, is a tumor suppressor gene associated with the inhibition of angiogenesis and apoptosis, cell cycle exit, fibronectin matrix assembly, and proteolysis. |
2004-03-08 |
2023-08-12 |
Not clear |
| Z Dzierzewicz, A Orchel, B Parfiniewicz, L Weglarz, J Stojko, G Swierczek-Zieba, T Wilczo. The delay of anoikis due to the inhibition of protein tyrosine dephosphorylation enables the maintenance of normal rat colonocyte primary culture. Folia histochemica et cytobiologica. vol 41. issue 4. 2004-03-04. PMID:14677762. |
apoptosis induced by detachment of cells from the extracellular matrix (anoikis) appears to be one of the main obstacles in attempts to establish long-term primary culture of normal colonocytes. |
2004-03-04 |
2023-08-12 |
rat |
| R Bendardaf, H Lamlum, P Vihinen, R Ristamäki, J Laine, S Pyrhöne. Low collagenase-1 (MMP-1) and MT1-MMP expression levels are favourable survival markers in advanced colorectal carcinoma. Oncology. vol 65. issue 4. 2004-02-27. PMID:14707454. |
extracellular matrix degradation is required for invasive growth and metastasis formation in colorectal carcinoma; therefore, we examined matrix metalloproteinases expression (mmp-1, mmp-13 and mt1-mmp) and apoptosis in tumours from 49 patients with advanced colorectal disease. |
2004-02-27 |
2023-08-12 |
Not clear |
| Arantxa González, Begoña López, Javier Díe. Fibrosis in hypertensive heart disease: role of the renin-angiotensin-aldosterone system. The Medical clinics of North America. vol 88. issue 1. 2004-02-24. PMID:14871052. |
structural homogeneity of cardiac tissue is governed by mechanical and humoral factors that regulate cell growth, apoptosis, phenotype, and extracellular matrix turnover. |
2004-02-24 |
2023-08-12 |
Not clear |
| E Gottlieb, S M Armour, M H Harris, C B Thompso. Mitochondrial membrane potential regulates matrix configuration and cytochrome c release during apoptosis. Cell death and differentiation. vol 10. issue 6. 2004-02-19. PMID:12761579. |
mitochondrial membrane potential regulates matrix configuration and cytochrome c release during apoptosis. |
2004-02-19 |
2023-08-12 |
Not clear |
| E Gottlieb, S M Armour, M H Harris, C B Thompso. Mitochondrial membrane potential regulates matrix configuration and cytochrome c release during apoptosis. Cell death and differentiation. vol 10. issue 6. 2004-02-19. PMID:12761579. |
in this work we show that, at the onset of apoptosis, changes in mmp control matrix remodeling prior to cytochrome c release. |
2004-02-19 |
2023-08-12 |
Not clear |
| E Gottlieb, S M Armour, M H Harris, C B Thompso. Mitochondrial membrane potential regulates matrix configuration and cytochrome c release during apoptosis. Cell death and differentiation. vol 10. issue 6. 2004-02-19. PMID:12761579. |
matrix remodeling to the condensed state results in cristal unfolding and exposes cytochrome c to the intermembrane space facilitating its release from the mitochondria during apoptosis. |
2004-02-19 |
2023-08-12 |
Not clear |
| Michael Mauro, Andrey Zlatopolskiy, Thomas J Raife, Jeffrey Laurenc. Thienopyridine-linked thrombotic microangiopathy: association with endothelial cell apoptosis and activation of MAP kinase signalling cascades. British journal of haematology. vol 124. issue 2. 2004-02-11. PMID:14687031. |
as ticlopidine can disrupt production of extracellular matrix (ecm) components critical to microvascular endothelial cell (mvec) integrity in vitro, we explored the hypotheses that ticlopidine and ticlopidine-linked ttp plasmas induce mvec apoptosis in a manner similar to that of idiopathic ttp plasmas, and that ecm components and related mitogen-activated protein kinase (mapk) signalling cascades may be involved in this process. |
2004-02-11 |
2023-08-12 |
human |
| Guy Rosne. [Anoikis--a specific form of programmed cell death]. Harefuah. vol 142. issue 12. 2004-02-10. PMID:14702756. |
apoptosis triggered by cell detachment from the extracellular matrix, which occurs during hepatocyte isolation, is a phenomenon termed "anoikis". |
2004-02-10 |
2023-08-12 |
human |
| T M Camp, S C Tyagi, R M Senior, M R Hayden, S C Tyag. Gelatinase B(MMP-9) an apoptotic factor in diabetic transgenic mice. Diabetologia. vol 46. issue 10. 2004-01-30. PMID:12928773. |
although matrix metalloproteinase-9 (mmp-9) is specifically induced and apoptosis of endothelial cells is evidenced in diabetes mellitus, the mechanism of endocardial endothelial dysfunction in diabetes mellitus is not clear. |
2004-01-30 |
2023-08-12 |
mouse |
| Yan-Nien Liu, Bean-Bu Kang, J H Che. Transcriptional regulation of human osteopontin promoter by C/EBPalpha and AML-1 in metastatic cancer cells. Oncogene. vol 23. issue 1. 2004-01-28. PMID:14712233. |
it also mediates neovascularization, inhibits apoptosis, and plays important roles in extracellular matrix remodeling and angiogenesis. |
2004-01-28 |
2023-08-12 |
human |
| William J Murdoch, Michelle L Gottsc. Proteolytic mechanisms in the ovulatory folliculo-luteal transformation. Connective tissue research. vol 44. issue 1. 2004-01-22. PMID:12945804. |
tumor necrosis factor alpha progressively induces matrix metalloproteinase gene expression, apoptosis, and inflammatory necrosis. |
2004-01-22 |
2023-08-12 |
Not clear |
| Robert Sidbury, Nicole Neuschler, Erin Neuschler, Ping Sun, Xiao-qi Wang, Richard Miller, Mark Tomai, Elena Puscasiu, Sajiv Gugneja, Amy S Palle. Topically applied imiquimod inhibits vascular tumor growth in vivo. The Journal of investigative dermatology. vol 121. issue 5. 2004-01-22. PMID:14708627. |
imiquimod-treated tumors showed decreased tumor cell proliferation, increased tumor apoptosis, and increased expression of tissue inhibitor of matrix metalloproteinase-1 with decreased activity of matrix metalloproteinase-9. |
2004-01-22 |
2023-08-12 |
mouse |