| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M M Tinnemans, M H Lenders, G P ten Velde, F C Ramaekers, B Schutt. Alterations in cytoskeletal and nuclear matrix-associated proteins during apoptosis. European journal of cell biology. vol 68. issue 1. 1996-02-22. PMID:8549588. |
the persistence of nuclear matrix components is therefore a useful marker for the detection of apoptosis. |
1996-02-22 |
2023-08-12 |
Not clear |
| R C Bates, L F Lincz, G F Burn. Involvement of integrins in cell survival. Cancer metastasis reviews. vol 14. issue 3. 1996-02-20. PMID:8548868. |
the extracellular matrix (ecm) is known to play a regulatory role in cellular growth and differentiation, but only more recently has it been recognized as a regulator of apoptosis. |
1996-02-20 |
2023-08-12 |
Not clear |
| G J Gibson, W J Kohler, M B Schaffle. Chondrocyte apoptosis in endochondral ossification of chick sterna. Developmental dynamics : an official publication of the American Association of Anatomists. vol 203. issue 4. 1996-01-17. PMID:7496038. |
light microscopy of resorbing sterna demonstrated chondrocyte condensation at the interface with the invading vasculature and electron microscopy demonstrated a range of chondrocyte morphologies, including retraction from the pericellular matrix, cytoplasmic and nuclear condensation, and vesiculation suggestive of sequential changes characteristic of apoptosis. |
1996-01-17 |
2023-08-12 |
chicken |
| M Zweyer, R Bareggi, V Grill, M R Soranzo, R A Marugg, B M Riederer, P Narducci, A M Martell. Behavior of nuclear matrix proteins during camptothecin-induced apoptosis in HL-60 human leukemia cells. Experimental cell research. vol 221. issue 1. 1995-12-14. PMID:7589253. |
behavior of nuclear matrix proteins during camptothecin-induced apoptosis in hl-60 human leukemia cells. |
1995-12-14 |
2023-08-12 |
human |
| M Zweyer, R Bareggi, V Grill, M R Soranzo, R A Marugg, B M Riederer, P Narducci, A M Martell. Behavior of nuclear matrix proteins during camptothecin-induced apoptosis in HL-60 human leukemia cells. Experimental cell research. vol 221. issue 1. 1995-12-14. PMID:7589253. |
in this study we focused our attention on the behavior of four nuclear matrix proteins during the various stages of apoptosis in the hl-60 cell line exposed to the dna topoisomerase i inhibitor, camptothecin. |
1995-12-14 |
2023-08-12 |
human |
| M Zweyer, R Bareggi, V Grill, M R Soranzo, R A Marugg, B M Riederer, P Narducci, A M Martell. Behavior of nuclear matrix proteins during camptothecin-induced apoptosis in HL-60 human leukemia cells. Experimental cell research. vol 221. issue 1. 1995-12-14. PMID:7589253. |
indirect immunofluorescence experiments were performed to follow these nuclear matrix antigens during apoptosis. |
1995-12-14 |
2023-08-12 |
human |
| H A Gelbard, H J James, L R Sharer, S W Perry, Y Saito, A M Kazee, B M Blumberg, L G Epstei. Apoptotic neurons in brains from paediatric patients with HIV-1 encephalitis and progressive encephalopathy. Neuropathology and applied neurobiology. vol 21. issue 3. 1995-11-27. PMID:7477729. |
these findings suggest that neuronal apoptosis is unlikely to be associated with post-natal development except in early post-natal germinal matrix, and that it may instead represent the end result of specific pathological processes, such as hiv-1 encephalitis. |
1995-11-27 |
2023-08-12 |
human |
| M N Peraldi, E Rondea. [Experimental models of acute kidney failure]. La Revue du praticien. vol 45. issue 13. 1995-11-03. PMID:7569687. |
more recent studies have emphasized the cellular and molecular events occurring during the course of arf, including changes in cytoskeleton and matrix proteins, apoptosis and the role of heat shock proteins. |
1995-11-03 |
2023-08-12 |
Not clear |
| J Wels. Induction of apoptosis in breast cancer cells in response to vitamin D and antiestrogens. Biochemistry and cell biology = Biochimie et biologie cellulaire. vol 72. issue 11-12. 1995-10-05. PMID:7654327. |
we have shown that mcf-7 cells treated with 100 nm 1,25(oh)2d3 exhibit characteristic apoptotic morphology (pyknotic nuclei, chromatin and cytoplasmic condensation, nuclear matrix protein reorganization) within 48 h. in the experiments reported here, we examined the interactions between 1,25(oh)2d3 and the antiestrogen 4-hydroxytamoxifen (tam), which also induces apoptosis in mcf-7 cells. |
1995-10-05 |
2023-08-12 |
Not clear |
| J Wels. Induction of apoptosis in breast cancer cells in response to vitamin D and antiestrogens. Biochemistry and cell biology = Biochimie et biologie cellulaire. vol 72. issue 11-12. 1995-10-05. PMID:7654327. |
combined treatment with 1,25(oh)2d3 and tam enhances the degree of apoptosis assessed using morphological markers that identify chromatin and nuclear matrix protein condensation. |
1995-10-05 |
2023-08-12 |
Not clear |
| M A Lagarkova, O V Iarovaia, S V Razi. Large-scale fragmentation of mammalian DNA in the course of apoptosis proceeds via excision of chromosomal DNA loops and their oligomers. The Journal of biological chemistry. vol 270. issue 35. 1995-10-04. PMID:7657590. |
furthermore, the patterns of dna long-range fragmentation in the cells undergoing apoptosis were indistinguishable from the patterns of dna cleavage into chromosomal loops by the high salt-insoluble topoisomerase ii of the nuclear matrix. |
1995-10-04 |
2023-08-12 |
mouse |
| D G Hoyt, R J Mannix, J M Rusnak, B R Pitt, J S Laz. Collagen is a survival factor against LPS-induced apoptosis in cultured sheep pulmonary artery endothelial cells. The American journal of physiology. vol 269. issue 2 Pt 1. 1995-09-27. PMID:7653577. |
thus lps-induced apoptosis occurs in spaec after genotoxic damage and this process is suppressed by the extracellular matrix. |
1995-09-27 |
2023-08-12 |
Not clear |
| H C Anderso. Molecular biology of matrix vesicles. Clinical orthopaedics and related research. issue 314. 1995-09-14. PMID:7634645. |
matrix vesicle biogenesis in the growth plate is linked to the chondrocyte cell cycle and reflects a stage in programmed cell death (apoptosis). |
1995-09-14 |
2023-08-12 |
Not clear |
| Y J Geng, P Libb. Evidence for apoptosis in advanced human atheroma. Colocalization with interleukin-1 beta-converting enzyme. The American journal of pathology. vol 147. issue 2. 1995-09-12. PMID:7639325. |
apoptosis of vascular cells in fibrous cap may impede maintenance or repair of the matrix in this region and affect stability of the plaques. |
1995-09-12 |
2023-08-12 |
human |
| Z Zhang, K Vuori, J C Reed, E Ruoslaht. The alpha 5 beta 1 integrin supports survival of cells on fibronectin and up-regulates Bcl-2 expression. Proceedings of the National Academy of Sciences of the United States of America. vol 92. issue 13. 1995-08-03. PMID:7541142. |
anchorage-dependent cells that are prevented from attaching to an extracellular matrix substrate stop proliferating and may undergo apoptosis. |
1995-08-03 |
2023-08-12 |
Not clear |
| L Kokilev. Comparative study of induction of endogenous DNA degradation in rat liver nuclei and intact thymocytes. Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology. vol 111. issue 1. 1995-06-21. PMID:7749635. |
detachment of chromatin from the nuclear matrix attachment regions may be one of the possible mechanisms of switching off the genome function and triggering the multi-step process of endogenous chromatin degradation thus leading to cell death in terminal differentiation or stress-induced apoptosis. |
1995-06-21 |
2023-08-12 |
rat |
| J P Witty, T Lempka, R J Coffey, L M Matrisia. Decreased tumor formation in 7,12-dimethylbenzanthracene-treated stromelysin-1 transgenic mice is associated with alterations in mammary epithelial cell apoptosis. Cancer research. vol 55. issue 7. 1995-04-13. PMID:7882342. |
these results suggest that the expression of a single metalloproteinase, stromelysin-1, is insufficient for the progression of mammary adenocarcinomas to an invasive and metastatic phenotype, but that matrix degradation by metalloproteinases can alter basic processes of cell proliferation and apoptosis. |
1995-04-13 |
2023-08-12 |
mouse |
| D Patterton, W P Hayes, Y B Sh. Transcriptional activation of the matrix metalloproteinase gene stromelysin-3 coincides with thyroid hormone-induced cell death during frog metamorphosis. Developmental biology. vol 167. issue 1. 1995-03-16. PMID:7851646. |
at this time, primary intestinal epithelial cells are known to undergo cell death and replacement by secondary epithelial cells, arguing that st3 is involved in the modification of the extracellular matrix during apoptosis. |
1995-03-16 |
2023-08-12 |
Not clear |
| D Patterton, W P Hayes, Y B Sh. Transcriptional activation of the matrix metalloproteinase gene stromelysin-3 coincides with thyroid hormone-induced cell death during frog metamorphosis. Developmental biology. vol 167. issue 1. 1995-03-16. PMID:7851646. |
these findings implicate that st3 participates in the modification of the extracellular matrix during matamorphic apoptosis, but northern analyses using heterologous probes raise the possibility that additional matrix metalloproteinases may also be involved. |
1995-03-16 |
2023-08-12 |
Not clear |
| L M Desjardins, J P MacManu. An adherent cell model to study different stages of apoptosis. Experimental cell research. vol 216. issue 2. 1995-03-09. PMID:7843282. |
the main advantages of this adherent cell model are: (1) apoptosis occurs very slowly (minimum of 48 h) permitting the observation of progressive changes; (2) cells from four stages of apoptosis can be used to study the sequence of events of other biochemical and genetic factors involved in the process; and (3) extracellular matrix proteins are present in this model so their participation in apoptosis, if any, can be determined. |
1995-03-09 |
2023-08-12 |
Not clear |