| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Afshin Ghavami, Rachel A Hunt, Michael A Olsen, Jie Zhang, Deborah L Smith, Sachin Kalgaonkar, Zia Rahman, Kathleen H Youn. Differential effects of regulator of G protein signaling (RGS) proteins on serotonin 5-HT1A, 5-HT2A, and dopamine D2 receptor-mediated signaling and adenylyl cyclase activity. Cellular signalling. vol 16. issue 6. 2005-03-23. PMID:15093612. |
differential effects of regulator of g protein signaling (rgs) proteins on serotonin 5-ht1a, 5-ht2a, and dopamine d2 receptor-mediated signaling and adenylyl cyclase activity. |
2005-03-23 |
2023-08-12 |
Not clear |
| Robert Adamec, Katherine Creamer, Gerd D Bartoszyk, Paul Burto. Prophylactic and therapeutic effects of acute systemic injections of EMD 281014, a selective serotonin 2A receptor antagonist on anxiety induced by predator stress in rats. European journal of pharmacology. vol 504. issue 1-2. 2005-03-23. PMID:15507224. |
emd 281014, a new selective serotonin 5-ht2a receptor antagonist. |
2005-03-23 |
2023-08-12 |
rat |
| Toshihide Kurok. [Pharmacology of second-generation antipsychotics: a validity of the serotonin-dopamine hypothesis]. Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology. vol 24. issue 5. 2005-03-10. PMID:15658501. |
it has been proposed by meltzer (1989) that the interaction between serotonin (5-ht) and dopamine (da) systems may play a critical role in the mechanism of action for atypical antipsychotics because potent 5-ht2a receptor antagonism together with relatively weak d2 receptor antagonism could differentiate most atypical antipsychotics from typical antipsychotics. |
2005-03-10 |
2023-08-12 |
Not clear |
| Kuldip D Dave, Gayani S Fernando, Jennifer L Quinn, John A Harvey, Vincent J Aloy. Serotonin 5-HT2A receptors in the CA1 field of the hippocampus mediate head movements in the rabbit. Psychopharmacology. vol 176. issue 3-4. 2005-03-01. PMID:15107968. |
serotonin 5-ht2a receptors in the ca1 field of the hippocampus mediate head movements in the rabbit. |
2005-03-01 |
2023-08-12 |
rabbit |
| Catharine A Winstanley, David E H Theobald, Jeffrey W Dalley, Jeffrey C Glennon, Trevor W Robbin. 5-HT2A and 5-HT2C receptor antagonists have opposing effects on a measure of impulsivity: interactions with global 5-HT depletion. Psychopharmacology. vol 176. issue 3-4. 2005-03-01. PMID:15232674. |
5-ht2a and 5-ht2c receptor antagonists have opposing effects on a measure of impulsivity: interactions with global 5-ht depletion. |
2005-03-01 |
2023-08-12 |
rat |
| Geoffrey Andrew Lambert, Cathy Donaldson, Karen Lisa Hoskin, Peter Michael Boers, Alessandro Stefano Zagam. Dilatation induced by 5-HT in the middle meningeal artery of the anaesthetised cat. Naunyn-Schmiedeberg's archives of pharmacology. vol 369. issue 6. 2005-02-22. PMID:15197536. |
dose-response curves of vascular resistance changes to intravenous injection of 5-ht were not significantly affected by way100635 (5-ht1a antagonist), gr127935 (5-ht(1b/1d) antagonist), methiothepin (5-ht2c and 5-ht7 antagonist), ketanserin (5-ht2a antagonist), sb203186 (5-ht4 antagonist) or cervical sympathectomy, but were blocked by the 5-ht(3/4) antagonist tropisetron, the 5-ht3 antagonist ondansetron, the ganglion-blocking drug hexamethonium and by vagotomy. |
2005-02-22 |
2023-08-12 |
cat |
| Miho Sekiguchi, Shinichi Konno, Shin-ichi Kikuch. Effects of 5-HT2A receptor antagonist on blood flow in chronically compressed nerve roots. Journal of the peripheral nervous system : JPNS. vol 9. issue 4. 2005-02-22. PMID:15574139. |
a reduction of blood flow is an important mechanism for inducing nic and may be caused by a vasoconstrictive effect mediated by the serotonin 5-ht2a receptor in chronic cauda equina compression lesions. |
2005-02-22 |
2023-08-12 |
Not clear |
| Miho Sekiguchi, Shinichi Konno, Shin-ichi Kikuch. Effects of 5-HT2A receptor antagonist on blood flow in chronically compressed nerve roots. Journal of the peripheral nervous system : JPNS. vol 9. issue 4. 2005-02-22. PMID:15574139. |
one group received sarpogrelate hydrochloride (5-ht2a receptor antagonist: 5-htra) before administration of serotonin, and another group was administered 5-htra after administration of serotonin. |
2005-02-22 |
2023-08-12 |
Not clear |
| O V Andreenkov, L P Osipova, A V Kulikov, N K Popov. [Polymorphism of the serotonin system genes in some Finno-Ugric populations]. Genetika. vol 40. issue 6. 2005-02-10. PMID:15341275. |
polymorphic sites in the genes encoding monoamine oxidase a (mao-a), serotonin transporter (hsert) and 5-ht2a receptor were typed in khant and komi ethnic groups with the purpose of revealing possible interpopulation differences in genotype and allele frequencies. |
2005-02-10 |
2023-08-12 |
Not clear |
| Vadim D Khait, Yung-yu Huang, Gil Zalsman, Maria A Oquendo, David A Brent, Jill M Harkavy-Friedman, J John Man. Association of serotonin 5-HT2A receptor binding and the T102C polymorphism in depressed and healthy Caucasian subjects. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 30. issue 1. 2005-01-26. PMID:15483560. |
association of serotonin 5-ht2a receptor binding and the t102c polymorphism in depressed and healthy caucasian subjects. |
2005-01-26 |
2023-08-12 |
human |
| Vadim D Khait, Yung-yu Huang, Gil Zalsman, Maria A Oquendo, David A Brent, Jill M Harkavy-Friedman, J John Man. Association of serotonin 5-HT2A receptor binding and the T102C polymorphism in depressed and healthy Caucasian subjects. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 30. issue 1. 2005-01-26. PMID:15483560. |
serotonin 5-ht2a receptor (5-ht2a) binding is reported to be altered in individuals with suicidal behavior, mood disorders, and aggressive-impulsive traits. |
2005-01-26 |
2023-08-12 |
human |
| M Victoria Puig, Noemí Santana, Pau Celada, Guadalupe Mengod, Francesc Artiga. In vivo excitation of GABA interneurons in the medial prefrontal cortex through 5-HT3 receptors. Cerebral cortex (New York, N.Y. : 1991). vol 14. issue 12. 2005-01-25. PMID:15166106. |
serotonin (5-hydroxytryptamine, 5-ht) controls pyramidal cell activity in prefrontal cortex (pfc) through various receptors, in particular, 5-ht1a and 5-ht2a receptors. |
2005-01-25 |
2023-08-12 |
rat |
| Claudia Somme. Serotonin in pain and analgesia: actions in the periphery. Molecular neurobiology. vol 30. issue 2. 2005-01-19. PMID:15475622. |
5-ht receptors of the 5-ht3 and 5-ht2a subtype are present on c-fibers. |
2005-01-19 |
2023-08-12 |
Not clear |
| Demet Akin, D Hal Manier, Elaine Sanders-Bush, Richard C Shelto. Decreased serotonin 5-HT2A receptor-stimulated phosphoinositide signaling in fibroblasts from melancholic depressed patients. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 29. issue 11. 2005-01-11. PMID:15187984. |
decreased serotonin 5-ht2a receptor-stimulated phosphoinositide signaling in fibroblasts from melancholic depressed patients. |
2005-01-11 |
2023-08-12 |
Not clear |
| Darius K Shayegan, Stephen M Stah. Atypical antipsychotics: matching receptor profile to individual patient's clinical profile. CNS spectrums. vol 9. issue 10 Suppl 11. 2005-01-04. PMID:15475871. |
atypical antipsychotics are also a heterogeneous group of agents that have complex pharmacologic entities, acting upon multiple dopamine receptors (d2, d1, d3, and d4) and multiple serotonin receptors (5-ht2a, 5-ht2c, 5-ht1a, and 5-ht1d, among others). |
2005-01-04 |
2023-08-12 |
Not clear |
| David Dietz, Michael Vogel, Steven Rubin, Timothy Moran, Kathryn Carbone, Mikhail Pletniko. Developmental alterations in serotoninergic neurotransmission in Borna disease virus (BDV)-infected rats: a multidisciplinary analysis. Journal of neurovirology. vol 10. issue 5. 2004-12-30. PMID:15385249. |
the present study sought to provide more insights into postnatal virus-associated alterations in 5-ht neurotransmission by evaluating the density of 5-ht1a receptors in the hippocampus and 5-ht2a receptors in the cortex, regional 5-ht tissue concentrations, behavioral responses to a 5-ht agonist, quipazine, and numbers of neurons in specific subfields of the hippocampus on days 7, 14, and 30 after neonatal bdv infection in lewis rats. |
2004-12-30 |
2023-08-12 |
rat |
| David Dietz, Michael Vogel, Steven Rubin, Timothy Moran, Kathryn Carbone, Mikhail Pletniko. Developmental alterations in serotoninergic neurotransmission in Borna disease virus (BDV)-infected rats: a multidisciplinary analysis. Journal of neurovirology. vol 10. issue 5. 2004-12-30. PMID:15385249. |
neonatal bdv infection was found to be associated with a gradual increase in the density of 5-ht2a and 5-ht1a postsynaptic receptors followed by an elevation of 5-ht contents at both the levels of synaptic terminals (i.e., cortex and hippocampus) and cell bodies (i.e., raphe nuclei). |
2004-12-30 |
2023-08-12 |
rat |
| C Reist, C Mazzanti, R Vu, K Fujimoto, D Goldma. Inter-relationships of intermediate phenotypes for serotonin function, impulsivity, and a 5-HT2A candidate allele: His452Tyr. Molecular psychiatry. vol 9. issue 9. 2004-12-08. PMID:15037867. |
inter-relationships of intermediate phenotypes for serotonin function, impulsivity, and a 5-ht2a candidate allele: his452tyr. |
2004-12-08 |
2023-08-12 |
human |
| Isabelle Cloëz-Tayarani, Usamah S Kayyali, Barry L Fanburg, Jean-Marc Cavaillo. 5-HT activates ERK MAP kinase in cultured-human peripheral blood mononuclear cells via 5-HT1A receptors. Life sciences. vol 76. issue 4. 2004-12-07. PMID:15530505. |
a 5-ht2a antagonist, ketanserin, and a 5-ht transport inhibitor, fluoxetine, both failed to block the activation of erk by 5-ht. |
2004-12-07 |
2023-08-12 |
human |
| Esther Gómez-Gil, Cristóbal Gastó, Marta Carretero, Maribel Díaz-Ricart, Manel Salamero, Ricard Navinés, Ginés Escola. Decrease of the platelet 5-HT2A receptor function by long-term imipramine treatment in endogenous depression. Human psychopharmacology. vol 19. issue 4. 2004-12-02. PMID:15181653. |
animal studies have found that many antidepressants induce decreases in both the density and the functional activity of the serotonin 2a (5-ht2a) receptor subtype. |
2004-12-02 |
2023-08-12 |
Not clear |