| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A Hardy, B Palouzier-Paulignan, A Duchamp, J-P Royet, P Duchamp-Vire. 5-Hydroxytryptamine action in the rat olfactory bulb: in vitro electrophysiological patch-clamp recordings of juxtaglomerular and mitral cells. Neuroscience. vol 131. issue 3. 2005-06-06. PMID:15730876. |
the involved gabaergic neurons are hypothesized to be juxtaglomerular and granular cells, on which serotonin would act mainly via 5ht2c and via 5ht2a receptors respectively. |
2005-06-06 |
2023-08-12 |
rat |
| A Hardy, B Palouzier-Paulignan, A Duchamp, J-P Royet, P Duchamp-Vire. 5-Hydroxytryptamine action in the rat olfactory bulb: in vitro electrophysiological patch-clamp recordings of juxtaglomerular and mitral cells. Neuroscience. vol 131. issue 3. 2005-06-06. PMID:15730876. |
the second subset of mitral cells (22.3%, n=54) were directly depolarized by serotonin acting through 5ht2a receptors. |
2005-06-06 |
2023-08-12 |
rat |
| Klaus Lieb, Lisa Biersack, Anne Waschbisch, Sonja Orlikowski, Ravi Shankar Akundi, Eduardo Candelario-Jalil, Michael Hüll, Bernd L Fiebic. Serotonin via 5-HT7 receptors activates p38 mitogen-activated protein kinase and protein kinase C epsilon resulting in interleukin-6 synthesis in human U373 MG astrocytoma cells. Journal of neurochemistry. vol 93. issue 3. 2005-06-03. PMID:15836614. |
we identified several 5-ht receptors to be expressed on u373 mg cells, including the 5-ht1d, 5-ht2a, 5-ht3 and 5-ht7 receptors. |
2005-06-03 |
2023-08-12 |
human |
| E Calama, A Morán, A V Ortiz de Urbina, M L Martín, L San Romá. Vasoconstrictor responses to 5-hydroxytryptamine in the autoperfused hindquarters of spontaneously hypertensive rats. Pharmacology. vol 71. issue 2. 2005-05-19. PMID:15118345. |
our data suggest that the vasoconstrictor response induced by 5-ht in the autoperfused hindquarters of shr is mainly mediated by the activation of 5-ht2a and 5-ht2c receptors. |
2005-05-19 |
2023-08-12 |
rat |
| Philip Gorwood, Laurence Lanfumey, Michel Hamo. [Alcohol dependence and polymorphisms of serotonin-related genes]. Medecine sciences : M/S. vol 20. issue 12. 2005-05-17. PMID:15581469. |
other genes coding for serotonin receptors were analysed with mainly negative results, for example the 5-ht2a, 5-ht2c, 5-ht5a and 5-ht7 receptors. |
2005-05-17 |
2023-08-12 |
human |
| Mercedes Delgado, Anne G Caicoya, Virginia Greciano, Bellinda Benhamú, María Luz López-Rodríguez, María Soledad Fernández-Alfonso, Miguel A Pozo, Jorge Manzanares, José A Fuente. Anxiolytic-like effect of a serotonergic ligand with high affinity for 5-HT1A, 5-HT2A and 5-HT3 receptors. European journal of pharmacology. vol 511. issue 1. 2005-05-16. PMID:15777774. |
s-(-)-2-[[4-(napht-1-yl)piperazin-1-yl]methyl]-1,4-dioxoperhydropyrrolo[1,2-alpha]-pyrazine (csp-2503) is a serotonin (5-ht) receptor ligand with selectivity and high affinity for 5-ht1a, 5-ht2a and 5-ht3 receptors. |
2005-05-16 |
2023-08-12 |
human |
| M V Puig, P Celada, F Artiga. [Serotonergic control of prefrontal cortex]. Revista de neurologia. vol 39. issue 6. 2005-05-12. PMID:15467993. |
although the exact role of serotonergic neurotransmission in pfc remains largely unknown, the pfc contains a very large density or serotonin 5-ht1a (inhibitory) and 5-ht2a (excitatory) receptors. |
2005-05-12 |
2023-08-12 |
Not clear |
| Su-Jane Wan. Potential antidepressant LY 367265 presynaptically inhibits the release of glutamate in rat cerebral cortex. Synapse (New York, N.Y.). vol 55. issue 3. 2005-05-11. PMID:15602751. |
in this study, the effect of the potential antidepressant ly 367265, an inhibitor of the 5-hydroxytryptamine (5-ht) transporter and 5-ht2a receptor antagonist, on the release of endogenous glutamate was investigated in nerve terminals purified from rat cerebral cortex using an on-line enzyme-coupled fluorimetric assay. |
2005-05-11 |
2023-08-12 |
rat |
| Medhane G Cumbay, Val J Watt. Galphaq potentiation of adenylate cyclase type 9 activity through a Ca2+/calmodulin-dependent pathway. Biochemical pharmacology. vol 69. issue 8. 2005-05-11. PMID:15794946. |
contrary to the anticipated inhibitory effect of activating pkcs through gq-coupled receptors, activation of transiently expressed gq-coupled serotonin 5-ht2a or muscarinic m5 receptors resulted in the potentiation of isoproterenol-stimulated cyclic amp accumulation in hek293 cells stably expressing ac9 (hek-ac9). |
2005-05-11 |
2023-08-12 |
Not clear |
| Jordi Serrats, Guadalupe Mengod, Roser Corté. Expression of serotonin 5-HT2C receptors in GABAergic cells of the anterior raphe nuclei. Journal of chemical neuroanatomy. vol 29. issue 2. 2005-05-03. PMID:15652696. |
according to this model, the excitation of gabaergic interneurons through these 5-ht2c (and also 5-ht2a) receptors would result in the suppression of 5-ht cell firing. |
2005-05-03 |
2023-08-12 |
rat |
| M Lüttgen, S O Ogren, B Meiste. 5-HT1A receptor mRNA and immunoreactivity in the rat medial septum/diagonal band of Broca-relationships to GABAergic and cholinergic neurons. Journal of chemical neuroanatomy. vol 29. issue 2. 2005-05-03. PMID:15652697. |
in addition, 5-ht may exert its effects in the msdb via cells expressing both 5-ht1a and 5-ht2a receptors. |
2005-05-03 |
2023-08-12 |
rat |
| David D Fuller, Tracy L Baker-Herman, Francis J Golder, Nicholas J Doperalski, Jyoti J Watters, Gordon S Mitchel. Cervical spinal cord injury upregulates ventral spinal 5-HT2A receptors. Journal of neurotrauma. vol 22. issue 2. 2005-05-03. PMID:15716627. |
following chronic c2 spinal hemisection (c2hs), crossed spinal pathways to phrenic motoneurons exhibit a slow, spontaneous increase in efficacy by a serotonin (5-ht)-dependent mechanism associated with 5-ht2a receptor activation. |
2005-05-03 |
2023-08-12 |
rat |
| David D Fuller, Tracy L Baker-Herman, Francis J Golder, Nicholas J Doperalski, Jyoti J Watters, Gordon S Mitchel. Cervical spinal cord injury upregulates ventral spinal 5-HT2A receptors. Journal of neurotrauma. vol 22. issue 2. 2005-05-03. PMID:15716627. |
we hypothesized that chronic c2hs would increase 5-ht and 5-ht2a receptor expression in ventral cervical spinal segments containing phrenic motoneurons. |
2005-05-03 |
2023-08-12 |
rat |
| David D Fuller, Tracy L Baker-Herman, Francis J Golder, Nicholas J Doperalski, Jyoti J Watters, Gordon S Mitchel. Cervical spinal cord injury upregulates ventral spinal 5-HT2A receptors. Journal of neurotrauma. vol 22. issue 2. 2005-05-03. PMID:15716627. |
in addition, we hypothesized that cih exposure would further increase 5-ht and 5-ht2a receptor density in this region. |
2005-05-03 |
2023-08-12 |
rat |
| Masashi Fujita, Tetsuo Minamino, Shoji Sanada, Hiroshi Asanuma, Akio Hirata, Hisakazu Ogita, Ken-ichiro Okada, Osamu Tsukamoto, Seiji Takashima, Hitonobu Tomoike, Koichi Node, Masatsugu Hori, Masafumi Kitakaz. Selective blockade of serotonin 5-HT2A receptor increases coronary blood flow via augmented cardiac nitric oxide release through 5-HT1B receptor in hypoperfused canine hearts. Journal of molecular and cellular cardiology. vol 37. issue 6. 2005-04-19. PMID:15572052. |
selective blockade of serotonin 5-ht2a receptor increases coronary blood flow via augmented cardiac nitric oxide release through 5-ht1b receptor in hypoperfused canine hearts. |
2005-04-19 |
2023-08-12 |
Not clear |
| Masashi Fujita, Tetsuo Minamino, Shoji Sanada, Hiroshi Asanuma, Akio Hirata, Hisakazu Ogita, Ken-ichiro Okada, Osamu Tsukamoto, Seiji Takashima, Hitonobu Tomoike, Koichi Node, Masatsugu Hori, Masafumi Kitakaz. Selective blockade of serotonin 5-HT2A receptor increases coronary blood flow via augmented cardiac nitric oxide release through 5-HT1B receptor in hypoperfused canine hearts. Journal of molecular and cellular cardiology. vol 37. issue 6. 2005-04-19. PMID:15572052. |
serotonin (5-hydroxytryptamine [5-ht]), which induces vasoconstriction via 5-ht2a receptors in smooth muscle cells and vasodilation through activating nitric oxide (no) synthase (nos) via 5-ht1b receptors in endothelial cells, possesses divergent effects on regulating vascular tone. |
2005-04-19 |
2023-08-12 |
Not clear |
| Amy K L Banes, Seán M Shaw, Amany Tawfik, Bela P Patel, Safia Ogbi, David Fulton, Mario B Marrer. Activation of the JAK/STAT pathway in vascular smooth muscle by serotonin. American journal of physiology. Cell physiology. vol 288. issue 4. 2005-04-19. PMID:15601754. |
treatment with the 5-ht2a receptor antagonist ketanserin (10 nm) inhibited jak2 activation by 5-ht. |
2005-04-19 |
2023-08-12 |
rat |
| Amy K L Banes, Seán M Shaw, Amany Tawfik, Bela P Patel, Safia Ogbi, David Fulton, Mario B Marrer. Activation of the JAK/STAT pathway in vascular smooth muscle by serotonin. American journal of physiology. Cell physiology. vol 288. issue 4. 2005-04-19. PMID:15601754. |
therefore, we conclude that 5-ht activates jak2, jak1, and stat1 via the 5-ht2a receptors in a reactive oxygen species-independent manner under both normal and high glucose conditions. |
2005-04-19 |
2023-08-12 |
rat |
| Yogesh Dwivedi, Amal C Mondal, Gurubasanagouda V Payappagoudar, Hooriyah S Rizav. Differential regulation of serotonin (5HT)2A receptor mRNA and protein levels after single and repeated stress in rat brain: role in learned helplessness behavior. Neuropharmacology. vol 48. issue 2. 2005-04-13. PMID:15695159. |
to examine the role of serotonergic (5ht) mechanisms in such behavior, we studied the expression of 5ht2a receptors in different brain areas of rats, and further investigated whether the alterations in expression of 5ht2a receptors are similar after single versus repeated stress. |
2005-04-13 |
2023-08-12 |
rat |
| Christopher Bishop, Jennifer L Tessmer, Thomas Ullrich, Kenner C Rice, Paul D Walke. Serotonin 5-HT2A receptors underlie increased motor behaviors induced in dopamine-depleted rats by intrastriatal 5-HT2A/2C agonism. The Journal of pharmacology and experimental therapeutics. vol 310. issue 2. 2005-03-28. PMID:15044557. |
serotonin 5-ht2a receptors underlie increased motor behaviors induced in dopamine-depleted rats by intrastriatal 5-ht2a/2c agonism. |
2005-03-28 |
2023-08-12 |
rat |