| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| In-Cheol Yeo, Nam Keun Lee, Chang-Jun Cha, Young Tae Hah. Narrow antagonistic activity of antimicrobial peptide from Bacillus subtilis SCK-2 against Bacillus cereus. Journal of bioscience and bioengineering. vol 112. issue 4. 2012-08-27. PMID:21783410. |
amp ic-1 was found to contain about 33 residues and 13 types of amino acids: cys, asp or asn, glu or gln, ser, gly, arg, thr, ala, pro, val, ile, leu, and lys. |
2012-08-27 |
2023-08-12 |
human |
| Elena Segala, Wladimir Sougakoff, Aurelie Nevejans-Chauffour, Vincent Jarlier, Stephanie Petrell. New mutations in the mycobacterial ATP synthase: new insights into the binding of the diarylquinoline TMC207 to the ATP synthase C-ring structure. Antimicrobial agents and chemotherapy. vol 56. issue 5. 2012-08-17. PMID:22354303. |
six distinct mutations, asp28 → gly, asp28 → ala, leu59 → val, glu61 → asp, ala63 → pro, and ile66 → met, have been identified in the subunit c forming a c ring in the atp synthase. |
2012-08-17 |
2023-08-12 |
Not clear |
| Ana C Figueiredo, Cristina C Clement, Sheuli Zakia, Julian Gingold, Manfred Philipp, Pedro J B Pereir. Rational design and characterization of D-Phe-Pro-D-Arg-derived direct thrombin inhibitors. PloS one. vol 7. issue 3. 2012-08-03. PMID:22457833. |
the most potent non-covalent and proteolysis-resistant inhibitors contain small hydrophobic or polar amino acids (gly, ala, ser, cys, thr) at the p1' position. |
2012-08-03 |
2023-08-12 |
human |
| Yu Chen, M T Rodger. Structural and energetic effects in the molecular recognition of amino acids by 18-crown-6. Journal of the American Chemical Society. vol 134. issue 13. 2012-08-02. PMID:22400976. |
the aas examined in this work include glycine (gly), alanine (ala), lysine (lys), histidine (his), and arginine (arg). |
2012-08-02 |
2023-08-12 |
Not clear |
| Yu Chen, M T Rodger. Structural and energetic effects in the molecular recognition of amino acids by 18-crown-6. Journal of the American Chemical Society. vol 134. issue 13. 2012-08-02. PMID:22400976. |
the proton affinities (pas) of gly and ala are lower than the pa of 18c6, whereas the pas of lys, his, and arg exceed that of 18c6. |
2012-08-02 |
2023-08-12 |
Not clear |
| Yu Chen, M T Rodger. Structural and energetic effects in the molecular recognition of amino acids by 18-crown-6. Journal of the American Chemical Society. vol 134. issue 13. 2012-08-02. PMID:22400976. |
cid of the complexes to gly and ala produces h(+)(18c6) as the dominant and lowest energy pathway. |
2012-08-02 |
2023-08-12 |
Not clear |
| Yu Chen, M T Rodger. Structural and energetic effects in the molecular recognition of amino acids by 18-crown-6. Journal of the American Chemical Society. vol 134. issue 13. 2012-08-02. PMID:22400976. |
gly and ala exhibit greater 18c6 binding affinities than lys, suggesting that the n-terminal amino group provides another favorable binding site for 18c6. |
2012-08-02 |
2023-08-12 |
Not clear |
| Didier Jollivet, Jean Mary, Nicolas Gagnière, Arnaud Tanguy, Eric Fontanillas, Isabelle Boutet, Stéphane Hourdez, Béatrice Segurens, Jean Weissenbach, Olivier Poch, Odile Lecompt. Proteome adaptation to high temperatures in the ectothermic hydrothermal vent Pompeii worm. PloS one. vol 7. issue 2. 2012-07-31. PMID:22348046. |
in addition, the pompeii worm displays a set of amino-acid change patterns that may explain its greater thermotolerance, with a significant increase in tyr, lys and ala against val, met and gly. |
2012-07-31 |
2023-08-12 |
Not clear |
| Joshua Lessing, Santanu Roy, Mike Reppert, Marcel Baer, Dominik Marx, Thomas La Cour Jansen, Jasper Knoester, Andrei Tokmakof. Identifying residual structure in intrinsically disordered systems: a 2D IR spectroscopic study of the GVGXPGVG peptide. Journal of the American Chemical Society. vol 134. issue 11. 2012-07-25. PMID:22356513. |
this analysis revealed that changing the size of the side chain at the x amino acid site from gly to ala to val substantially alters the conformation of the peptide. |
2012-07-25 |
2023-08-12 |
Not clear |
| Linliang Yu, Wei Lu, Yinan We. AcrB trimer stability and efflux activity, insight from mutagenesis studies. PloS one. vol 6. issue 12. 2012-07-20. PMID:22163011. |
we replaced p223 separately with five residues, including ala, val, tyr, asn, and gly, and found that acrb(p223g) was the least active. |
2012-07-20 |
2023-08-12 |
Not clear |
| Mauricio Mora-Pale, Seok Joon Kwon, Robert J Linhardt, Jonathan S Dordic. Trimer hydroxylated quinone derived from apocynin targets cysteine residues of p47phox preventing the activation of human vascular NADPH oxidase. Free radical biology & medicine. vol 52. issue 5. 2012-06-04. PMID:22240153. |
mutants of p47(phox), in which each cys was individually replaced by ala (at residues 111, 196, and 378) or gly (at residue 98), were generated to evaluate their individual importance in iiihyq-mediated inhibition of p47(phox) interaction with p22(phox). |
2012-06-04 |
2023-08-12 |
human |
| Jianquan Yang, Yubin Mia. Substitution of Gly with Ala enhanced the melanoma uptake of technetium-99m-labeled Arg-Ala-Asp-conjugated alpha-melanocyte stimulating hormone peptide. Bioorganic & medicinal chemistry letters. vol 22. issue 4. 2012-05-31. PMID:22297112. |
substitution of gly with ala enhanced the melanoma uptake of technetium-99m-labeled arg-ala-asp-conjugated alpha-melanocyte stimulating hormone peptide. |
2012-05-31 |
2023-08-12 |
mouse |
| Jianquan Yang, Yubin Mia. Substitution of Gly with Ala enhanced the melanoma uptake of technetium-99m-labeled Arg-Ala-Asp-conjugated alpha-melanocyte stimulating hormone peptide. Bioorganic & medicinal chemistry letters. vol 22. issue 4. 2012-05-31. PMID:22297112. |
the substitution of gly with ala significantly enhanced the melanoma uptake of (99m)tc-rad-lys-(arg(11))ccmsh compared to (99m)tc-rgd-lys-(arg(11))ccmsh in b16/f1 melanoma-bearing c57 mice, providing a new insight into the design of α-msh peptides for melanoma targeting. |
2012-05-31 |
2023-08-12 |
mouse |
| Michael C Owen, Milán Szori, Imre G Csizmadia, Bela Viskolc. Conformation-dependent ˙OH/H2O2 hydrogen abstraction reaction cycles of Gly and Ala residues: a comparative theoretical study. The journal of physical chemistry. B. vol 116. issue 3. 2012-05-22. PMID:22168541. |
conformation-dependent ˙oh/h2o2 hydrogen abstraction reaction cycles of gly and ala residues: a comparative theoretical study. |
2012-05-22 |
2023-08-12 |
Not clear |
| Michael C Owen, Milán Szori, Imre G Csizmadia, Bela Viskolc. Conformation-dependent ˙OH/H2O2 hydrogen abstraction reaction cycles of Gly and Ala residues: a comparative theoretical study. The journal of physical chemistry. B. vol 116. issue 3. 2012-05-22. PMID:22168541. |
to determine if (•)oh can initiate the unfolding of an amino acid residue, the elementary reaction coordinates of h abstraction by (•)oh different conformations (β(l), γ(l), γ(d), α(l), and α(d)) of gly and ala dimethyl amides were computed using first-principles quantum computations. |
2012-05-22 |
2023-08-12 |
Not clear |
| Michael C Owen, Milán Szori, Imre G Csizmadia, Bela Viskolc. Conformation-dependent ˙OH/H2O2 hydrogen abstraction reaction cycles of Gly and Ala residues: a comparative theoretical study. The journal of physical chemistry. B. vol 116. issue 3. 2012-05-22. PMID:22168541. |
the structures of gly and ala in the elementary reaction steps were compared to the conformers of the gly, gly(•), ala, and ala(•) structures in the absence of (•)oh/h(2)o, which were identified by optimizing the minima of the respective potential energy surfaces. |
2012-05-22 |
2023-08-12 |
Not clear |
| Michael C Owen, Milán Szori, Imre G Csizmadia, Bela Viskolc. Conformation-dependent ˙OH/H2O2 hydrogen abstraction reaction cycles of Gly and Ala residues: a comparative theoretical study. The journal of physical chemistry. B. vol 116. issue 3. 2012-05-22. PMID:22168541. |
a dramatic change in conformation is observed in the gly and ala conformers after conversion to gly(•) and ala(•), respectively, and this change can be monitored along the minimal energy pathway. |
2012-05-22 |
2023-08-12 |
Not clear |
| Michael C Owen, Milán Szori, Imre G Csizmadia, Bela Viskolc. Conformation-dependent ˙OH/H2O2 hydrogen abstraction reaction cycles of Gly and Ala residues: a comparative theoretical study. The journal of physical chemistry. B. vol 116. issue 3. 2012-05-22. PMID:22168541. |
the β(l) conformer of gly (-0.3 kj mol(-1)) and ala (-1.6 kj mol(-1)) form the lowest-lying transition states in the reaction with (•)oh, whereas the side chain of ala strongly destabilizes the α conformers compared to the γ conformers, which could cause the lower reactivity shown in ala. |
2012-05-22 |
2023-08-12 |
Not clear |
| Michael C Owen, Milán Szori, Imre G Csizmadia, Bela Viskolc. Conformation-dependent ˙OH/H2O2 hydrogen abstraction reaction cycles of Gly and Ala residues: a comparative theoretical study. The journal of physical chemistry. B. vol 116. issue 3. 2012-05-22. PMID:22168541. |
the energy of subsequent hydrogen abstraction reactions between ala(•) and gly(•) and h(2)o(2) remains approximately 90 kj mol(-1) below the entrance level of the (•)oh reaction, indicating that the (•)oh radical can initiate an α to β transition in an amino acid residue if a molecule such as h(2)o(2) can provide the hydrogen atom necessary to re-form gly and ala. |
2012-05-22 |
2023-08-12 |
Not clear |
| Fernando Diez-García, Irene Gómez-Pinto, Avijit Chakrabartty, Carlos González, Douglas V Laurent. Conformation specificity and arene binding in a peptide composed only of Lys, Ile, Ala and Gly. European biophysics journal : EBJ. vol 41. issue 1. 2012-05-11. PMID:22038076. |
conformation specificity and arene binding in a peptide composed only of lys, ile, ala and gly. |
2012-05-11 |
2023-08-12 |
Not clear |