| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Márcia M T Moraes, Marcella C Galvão, Danilo Cabral, Cideli P Coelho, Nicolle Queiroz-Hazarbassanov, Maria F M Martins, Eduardo F Bondan, Maria M Bernardi, Thiago Berti Kirste. Propentofylline Prevents Sickness Behavior and Depressive-Like Behavior Induced by Lipopolysaccharide in Rats via Neuroinflammatory Pathway. PloS one. vol 12. issue 1. 2017-08-28. PMID:28056040. |
anxiety-like behavior (light-dark test), depressive-like behavior (forced swim test), plasmatic levels of the brain-derived neurotrophic factor (bdnf, depression biomarker), and central glial fibrillary acidic protein (gfap) expression (an astrocyte biomarker) were also evaluated. |
2017-08-28 |
2023-08-13 |
rat |
| Yoichiro Shinohara, Ayumu Konno, Nobutaka Takahashi, Yasunori Matsuzaki, Shoji Kishi, Hirokazu Hira. Viral Vector-Based Dissection of Marmoset GFAP Promoter in Mouse and Marmoset Brains. PloS one. vol 11. issue 8. 2017-08-18. PMID:27571575. |
then, we verified whether the 0.3-kb gfap promoter retained astrocyte specificity in the marmoset cerebral cortex. |
2017-08-18 |
2023-08-13 |
mouse |
| M Natalia Marangoni, David Braun, Annie Situ, Ana L Moyano, Sergey Kalinin, Paul Polak, Maria I Givogri, Douglas L Feinstei. Differential effects on glial activation by a direct versus an indirect thrombin inhibitor. Journal of neuroimmunology. vol 297. 2017-08-17. PMID:27397090. |
after 4weeks, warfarin increased both astrocyte gfap and microglia iba-1 staining throughout the cns; whereas de reduced expression of both markers. |
2017-08-17 |
2023-08-13 |
mouse |
| Markel Olabarria, James E Goldma. Disorders of Astrocytes: Alexander Disease as a Model. Annual review of pathology. vol 12. 2017-08-17. PMID:28135564. |
we have been studying the astrocytes of alexander disease (axd), which is caused by heterozygous mutations in the gfap gene, which is the gene that encodes the major astrocyte intermediate filament protein. |
2017-08-17 |
2023-08-13 |
Not clear |
| Markel Olabarria, James E Goldma. Disorders of Astrocytes: Alexander Disease as a Model. Annual review of pathology. vol 12. 2017-08-17. PMID:28135564. |
axd is a primary astrocyte disease because gfap expression is specific to astrocytes in the central nervous system (cns). |
2017-08-17 |
2023-08-13 |
Not clear |
| Markel Olabarria, James E Goldma. Disorders of Astrocytes: Alexander Disease as a Model. Annual review of pathology. vol 12. 2017-08-17. PMID:28135564. |
the accumulation of extremely large amounts of gfap causes many molecular changes in astrocytes, including proteasome inhibition, stress kinase activation, mechanistic target of rapamycin (mtor) activation, loss of glutamate and potassium buffering capacity, loss of astrocyte coupling, and changes in cell morphology. |
2017-08-17 |
2023-08-13 |
Not clear |
| Rachel Waller, M Nicola Woodroofe, Stephen B Wharton, Paul G Ince, Simona Francese, Paul R Heath, Alex Cudzich-Madry, Ruth H Thomas, Natalie Rounding, Basil Sharrack, Julie E Simpso. Gene expression profiling of the astrocyte transcriptome in multiple sclerosis normal appearing white matter reveals a neuroprotective role. Journal of neuroimmunology. vol 299. 2017-08-14. PMID:27725112. |
astrocytes were isolated from control and nawm by laser capture microdissection (lcm), using glial fibrillary acidic protein (gfap) as a marker, and the astrocyte transcriptome determined using microarray analysis. |
2017-08-14 |
2023-08-13 |
Not clear |
| Darren Clarke, Marissa A Penrose, Alan R Harvey, Jennifer Rodger, Kristyn A Bate. Low intensity rTMS has sex-dependent effects on the local response of glia following a penetrating cortical stab injury. Experimental neurology. vol 295. 2017-08-14. PMID:28624361. |
immunohistochemistry was used to measure the effect of low intensity rtms (li-rtms) on gfap (astrocyte), iba1 (microglial), and cs56 (proteoglycan) expression in a unilateral penetrating cortical stab injury model of glial scarring in young adult and aged male and female c57bl6/j mice. |
2017-08-14 |
2023-08-13 |
mouse |
| A Trost, D Bruckner, A Kaser-Eichberger, K Motloch, B Bogner, C Runge, C Strohmaier, S Couillard-Despres, H A Reitsamer, F Schroed. Lymphatic and vascular markers in an optic nerve crush model in rat. Experimental eye research. vol 159. 2017-08-09. PMID:28315338. |
lesioned ons and unlesioned contralateral controls were analyzed 7 days (n = 5) and 14 days (n = 5) after onc, with the following markers: pdgfrb (pericyte), iba1 (microglia), cd68 (macrophages), reca (endothelial cell), gfap (astrocyte) as well as lyve-1 and podoplanin (pdpn; lymphatic markers). |
2017-08-09 |
2023-08-13 |
rat |
| Michael D Scofield, Hao Li, Benjamin M Siemsen, Kati L Healey, Phuong K Tran, Nicholas Woronoff, Heather A Boger, Peter W Kalivas, Kathryn J Reissne. Cocaine Self-Administration and Extinction Leads to Reduced Glial Fibrillary Acidic Protein Expression and Morphometric Features of Astrocytes in the Nucleus Accumbens Core. Biological psychiatry. vol 80. issue 3. 2017-08-07. PMID:26946381. |
we investigated the effects of extinction from daily cocaine self-administration on astrocyte characteristics including glial fibrillary acidic protein (gfap) expression, surface area, volume, and colocalization with a synaptic marker. |
2017-08-07 |
2023-08-13 |
Not clear |
| Hanzhang Liu, Wei Ji, Peipei Gong, Chun Liu, Chengwei Duan, Yilu Gao, Xiaojuan Liu, Dongmei Zhang, Shunxing Zhu, Leilei Gon. Spatiotemporal Patterns of RING1 Expression after Rat Spinal Cord Injury. Neurochemical research. vol 42. issue 4. 2017-08-04. PMID:28032293. |
meanwhile, we also found the co-localization of pcna, a famous marker of proliferative cells, with ring1 and gfap, which indicated ring1 might play a role in astrocyte proliferation after sci. |
2017-08-04 |
2023-08-13 |
rat |
| Osamu Imamura, Masaaki Arai, Minori Dateki, Kunio Takishim. Donepezil promotes differentiation of neural stem cells into mature oligodendrocytes at the expense of astrogenesis. Journal of neurochemistry. vol 140. issue 2. 2017-07-28. PMID:27664791. |
in contrast, the expression of the astrocyte marker glial fibrillary acidic protein (gfap) was down-regulated by donepezil in a dose- and time-dependent manner. |
2017-07-28 |
2023-08-13 |
mouse |
| Mario Van Poucke, Valentine Martlé, Leen Van Brantegem, Richard Ducatelle, Luc Van Ham, Sofie Bhatti, Luc J Peelma. A canine orthologue of the human GFAP c.716G>A (p.Arg239His) variant causes Alexander disease in a Labrador retriever. European journal of human genetics : EJHG. vol 24. issue 6. 2017-07-26. PMID:26486469. |
alexander disease (axd) is a fatal neurodegenerative disorder of astrocyte dysfunction in man, for which already a number of causal variants are described, mostly de novo dominant missense variants in the glial fibrillary acidic protein (gfap). |
2017-07-26 |
2023-08-13 |
human |
| Sachin Tripathi, Rajesh Kushwaha, Juhi Mishra, Manoj Kumar Gupta, Harish Kumar, Somali Sanyal, Dhirendra Singh, Sabyasachi Sanyal, Amogh Anant Sahasrabuddhe, Mohan Kamthan, Mohana Krishna Reddy Mudiam, Sanghamitra Bandyopadhya. Docosahexaenoic acid up-regulates both PI3K/AKT-dependent FABP7-PPARγ interaction and MKP3 that enhance GFAP in developing rat brain astrocytes. Journal of neurochemistry. vol 140. issue 1. 2017-07-13. PMID:27787894. |
the astrocyte marker, glial fibrillary acidic protein (gfap), has essential functions in the brain, but may trigger astroglial scarring when expressed in excess. |
2017-07-13 |
2023-08-13 |
rat |
| Helena Biasibetti, Paula Pierozan, André Felipe Rodrigues, Vanusa Manfredini, Angela T S Wys. Hypoxanthine Intrastriatal Administration Alters Neuroinflammatory Profile and Redox Status in Striatum of Infant and Young Adult Rats. Molecular neurobiology. vol 54. issue 4. 2017-07-11. PMID:27013467. |
microglial and astrocyte activation was seen by the increase in iba1 and gfap immunocontent, respectively, in striatum of infant rats. |
2017-07-11 |
2023-08-13 |
rat |
| Bruna Bellaver, Débora Guerini Souza, Diogo Onofre Souza, André Quincozes-Santo. Hippocampal Astrocyte Cultures from Adult and Aged Rats Reproduce Changes in Glial Functionality Observed in the Aging Brain. Molecular neurobiology. vol 54. issue 4. 2017-07-07. PMID:27026184. |
here, we show that the p21 senescence-associated gene and classical astrocyte markers, such as glial fibrillary acidic protein (gfap), vimentin, and actin, changed their expressions in adult and aged astrocytes. |
2017-07-07 |
2023-08-13 |
rat |
| Won-Yong Jeong, Jun-Beom Kim, Hyun-Jung Kim, Chan-Wha Ki. Extremely low-frequency electromagnetic field promotes astrocytic differentiation of human bone marrow mesenchymal stem cells by modulating SIRT1 expression. Bioscience, biotechnology, and biochemistry. vol 81. issue 7. 2017-07-07. PMID:28351214. |
the elfmf-treated cells showed increased levels of the astrocyte marker (gfap), while those of the early neuronal marker (nestin) and stemness marker (oct3/4) were downregulated. |
2017-07-07 |
2023-08-13 |
human |
| Wilma Helena Oliveira, Ana Karolina Nunes, Maria Eduarda Rocha França, Laise Aline Santos, Deniele Bezerra Lós, Sura Wanessa Rocha, Karla Patrícia Barbosa, Gabriel Barros Rodrigues, Christina Alves Peixot. Effects of metformin on inflammation and short-term memory in streptozotocin-induced diabetic mice. Brain research. vol 1644. 2017-06-29. PMID:27174003. |
treatment with metformin reduced the expression of gfap, iba-1 (astrocyte and microglial markers) and the inflammation markers (p-ikb, il-1 and vegf), while enhancing p-ampk and enos levels and increasing neuronal survival (fox-1 and neun). |
2017-06-29 |
2023-08-13 |
mouse |
| Xin Qi, Brandon Davis, Yung-Hsiao Chiang, Emily Filichia, Austin Barnett, Nigel H Greig, Barry Hoffer, Yu Lu. Dopaminergic neuron-specific deletion of p53 gene is neuroprotective in an experimental Parkinson's disease model. Journal of neurochemistry. vol 138. issue 5. 2017-06-14. PMID:27317935. |
astrocyte activation measured by gfap positive cells and gfap gene up-regulation in the striatum shows no difference between wt and da-p53 ko mice. |
2017-06-14 |
2023-08-13 |
mouse |
| Paulo Henrique S Botton, Daniela Pochmann, Andreia S Rocha, Fernanda Nunes, Amanda S Almeida, Daniela M Marques, Lisiane O Porciúncul. Aged mice receiving caffeine since adulthood show distinct patterns of anxiety-related behavior. Physiology & behavior. vol 170. 2017-06-13. PMID:27890589. |
because aging alters synaptic proteins, we also evaluated snap-25 (as a nerve terminals marker), gfap (as an astrocyte marker) and adenosine a |
2017-06-13 |
2023-08-13 |
mouse |