| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| David M Irvin, Robert S McNeill, Ryan E Bash, C Ryan Mille. Intrinsic Astrocyte Heterogeneity Influences Tumor Growth in Glioma Mouse Models. Brain pathology (Zurich, Switzerland). vol 27. issue 1. 2018-02-23. PMID:26762242. |
gfap astrocyte transformation induced uniformly rapid, regionally independent tumor growth, but transformation of glast astrocytes induced slowly growing tumors with significant regional bias. |
2018-02-23 |
2023-08-13 |
mouse |
| Yuzhou Liu, Le Wang, Chong Meng, Yingjie Zhou, Jie Lao, Xin Zha. A new model for the study of neuropathic pain after brachial plexus injury. Injury. vol 48. issue 2. 2018-02-01. PMID:27863697. |
the injured level of spinal cord was resected and the sections were processed for gfap (astrocyte) and iba1 (microglia) immunohistochemistry 3 weeks after surgeries. |
2018-02-01 |
2023-08-13 |
rat |
| Sebastien Gabel, Eric Koncina, Gauthier Dorban, Tony Heurtaux, Cindy Birck, Enrico Glaab, Alessandro Michelucci, Paul Heuschling, Luc Grandbarb. Inflammation Promotes a Conversion of Astrocytes into Neural Progenitor Cells via NF-κB Activation. Molecular neurobiology. vol 53. issue 8. 2018-01-22. PMID:26381429. |
a tnf treatment induces the decrease of specific astrocyte markers, such as glial fibrillary acidic protein (gfap) or genes related to glycogen metabolism, while a subset of these cells re-expresses immaturity markers, such as cd44, musashi-1, and oct4. |
2018-01-22 |
2023-08-13 |
Not clear |
| Clare J Wilhelm, Joel G Hashimoto, Melissa L Roberts, Shelley H Bloom, Melissa R Andrew, Kristine M Wire. Astrocyte Dysfunction Induced by Alcohol in Females but Not Males. Brain pathology (Zurich, Switzerland). vol 26. issue 4. 2018-01-02. PMID:26088166. |
consistent with this result, astrocyte activation was observed after exposure in female but not male animals, with reduced s100β levels in the anterior cingulate cortex and increased gfap(+) cells in the hippocampus. |
2018-01-02 |
2023-08-13 |
Not clear |
| Clare J Wilhelm, Joel G Hashimoto, Melissa L Roberts, Shelley H Bloom, Melissa R Andrew, Kristine M Wire. Astrocyte Dysfunction Induced by Alcohol in Females but Not Males. Brain pathology (Zurich, Switzerland). vol 26. issue 4. 2018-01-02. PMID:26088166. |
male astrocyte responses were consistent with astrocyte deactivation with reduced gfap expression during ethanol exposure. |
2018-01-02 |
2023-08-13 |
Not clear |
| Erica Zamberletti, Marina Gabaglio, Massimo Grilli, Pamela Prini, Alberto Catanese, Anna Pittaluga, Mario Marchi, Tiziana Rubino, Daniela Parolar. Long-term hippocampal glutamate synapse and astrocyte dysfunctions underlying the altered phenotype induced by adolescent THC treatment in male rats. Pharmacological research. vol 111. 2017-12-25. PMID:27422357. |
moreover, in the same brain region, adolescent thc treatment also resulted in a persistent neuroinflammatory state, characterized by increased expression of the astrocyte marker, gfap, increased levels of the pro-inflammatory markers, tnf-α, inos and cox-2, as well as a concomitant reduction of the anti-inflammatory cytokine, il-10. |
2017-12-25 |
2023-08-13 |
rat |
| Fernanda R Marins, Jennifer A Iddings, Marco A P Fontes, Jessica A Filos. Evidence that remodeling of insular cortex neurovascular unit contributes to hypertension-related sympathoexcitation. Physiological reports. vol 5. issue 5. 2017-12-07. PMID:28270592. |
additionally, ic from shr presented increased gfap immunoreactivity and contact between astrocyte processes and blood vessels. |
2017-12-07 |
2023-08-13 |
rat |
| M Toyoshima, W Akamatsu, Y Okada, T Ohnishi, S Balan, Y Hisano, Y Iwayama, T Toyota, T Matsumoto, N Itasaka, S Sugiyama, M Tanaka, M Yano, B Dean, H Okano, T Yoshikaw. Analysis of induced pluripotent stem cells carrying 22q11.2 deletion. Translational psychiatry. vol 6. issue 11. 2017-12-04. PMID:27801899. |
furthermore, we detected elevated expression of gfap, a gliogenic (astrocyte) marker, in postmortem brains from schizophrenia patients without the 22q11.2 deletion, whereas inflammation markers (il1b and il6) remained unchanged. |
2017-12-04 |
2023-08-13 |
mouse |
| Mayu Nishikawa, Hideki Mori, Masayuki Har. Analysis of ZIP (Zrt-, Irt-related protein) transporter gene expression in murine neural stem/progenitor cells. Environmental toxicology and pharmacology. vol 53. 2017-11-27. PMID:28527331. |
downregulation of nspc's marker (nes) and upregulation of differentiated cell markers (tubb3; neuron, gfap; astrocyte) occurred simultaneously. |
2017-11-27 |
2023-08-13 |
mouse |
| Swarnalatha Balasubramanian, John A Packard, Jennie B Leach, Elizabeth M Powel. Three-Dimensional Environment Sustains Morphological Heterogeneity and Promotes Phenotypic Progression During Astrocyte Development. Tissue engineering. Part A. vol 22. issue 11-12. 2017-11-20. PMID:27193766. |
to specifically study the effects of dimensionality, we used purified glial fibrillary acidic protein (gfap)-expressing primary cerebral cortical astrocyte cultures from single pups and characterized the cellular maturation profiles in 2d and 3d milieu. |
2017-11-20 |
2023-08-13 |
Not clear |
| Vasiliki Bitsika, Venceslas Duveau, Julia Simon-Areces, William Mullen, Corinne Roucard, Manousos Makridakis, George Mermelekas, Pantelis Savvopoulos, Antoine Depaulis, Antonia Vlaho. High-Throughput LC-MS/MS Proteomic Analysis of a Mouse Model of Mesiotemporal Lobe Epilepsy Predicts Microglial Activation Underlying Disease Development. Journal of proteome research. vol 15. issue 5. 2017-11-07. PMID:27057777. |
as a positive control, the astrocyte marker gfap was found to be upregulated (3dpi: 1.9 fold; 30dpi: 12.5 fold), also verified by ihc. |
2017-11-07 |
2023-08-13 |
mouse |
| Ingrid Morales, Alberto Sanchez, Clara Rodriguez-Sabate, Manuel Rodrigue. Striatal astrocytes engulf dopaminergic debris in Parkinson's disease: A study in an animal model. PloS one. vol 12. issue 10. 2017-10-27. PMID:29028815. |
free-spheroids were penetrated by astrocyte processes (fenestrated-spheroids) which made them immunoreactive for gfap and s100β, and which had some elements needed to continue the debris degradation (lamp1/lamp2). |
2017-10-27 |
2023-08-13 |
rat |
| Alexander A Sosunov, Guy M McKhann, James E Goldma. The origin of Rosenthal fibers and their contributions to astrocyte pathology in Alexander disease. Acta neuropathologica communications. vol 5. issue 1. 2017-10-25. PMID:28359321. |
they are the pathognomonic feature of the astrocyte pathology in alexander disease (axd), a neurodegenerative disorder caused by heterozygous mutations in the gfap gene, encoding glial fibrillary acidic protein (gfap). |
2017-10-25 |
2023-08-13 |
mouse |
| Alexander A Sosunov, Guy M McKhann, James E Goldma. The origin of Rosenthal fibers and their contributions to astrocyte pathology in Alexander disease. Acta neuropathologica communications. vol 5. issue 1. 2017-10-25. PMID:28359321. |
we have used mouse models of axd based on the overexpression of human gfap (transgenic, tg) and a point mutation in mouse gfap (knock-in, ki) to examine the formation of rfs and to find astrocyte changes that correlate with the appearance of rfs. |
2017-10-25 |
2023-08-13 |
mouse |
| Oskar Karlsson, Wojciech Michno, Yusuf Ransome, Jörg Hanriede. MALDI imaging delineates hippocampal glycosphingolipid changes associated with neurotoxin induced proteopathy following neonatal BMAA exposure. Biochimica et biophysica acta. Proteins and proteomics. vol 1865. issue 7. 2017-09-26. PMID:27956354. |
complementary immunohistochemistry experiments towards gfap and s100β further verified the role of increased astrocyte activity in bmaa-induced brain damage. |
2017-09-26 |
2023-08-13 |
rat |
| Joanna E Sowa, Joanna Ślusarczyk, Ewa Trojan, Katarzyna Chamera, Monika Leśkiewicz, Magdalena Regulska, Katarzyna Kotarska, Agnieszka Basta-Kai. Prenatal stress affects viability, activation, and chemokine signaling in astroglial cultures. Journal of neuroimmunology. vol 311. 2017-09-26. PMID:28844502. |
our results showed that prenatal stress lowered astrocyte viability and simultaneously increased gfap expression. |
2017-09-26 |
2023-08-13 |
Not clear |
| Hyesook Yoon, Grant Walters, Alex R Paulsen, Isobel A Scarisbric. Astrocyte heterogeneity across the brain and spinal cord occurs developmentally, in adulthood and in response to demyelination. PloS one. vol 12. issue 7. 2017-09-25. PMID:28700615. |
equivalent elevations in gfap, gfap/aldh1l1 ratios, and in il-6, were observed in primary astrocyte cultures derived from spinal cord compared to cortex. |
2017-09-25 |
2023-08-13 |
Not clear |
| Hyesook Yoon, Grant Walters, Alex R Paulsen, Isobel A Scarisbric. Astrocyte heterogeneity across the brain and spinal cord occurs developmentally, in adulthood and in response to demyelination. PloS one. vol 12. issue 7. 2017-09-25. PMID:28700615. |
altogether, these studies point to key differences in astrocyte abundance and the expression of gfap and il-6 across the brain and spinal cord that are positioned to influence regional specialization developmentally and responses occurring in the context of injury and disease. |
2017-09-25 |
2023-08-13 |
Not clear |
| Michal K Oklinski, Jung-Suk Lim, Hyo-Jung Choi, Paulina Oklinska, Mariusz T Skowronski, Tae-Hwan Kwo. Immunolocalization of Water Channel Proteins AQP1 and AQP4 in Rat Spinal Cord. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society. vol 62. issue 8. 2017-09-07. PMID:24828513. |
in contrast, aqp1 did not colocalize with gfap, an astrocyte marker, at any level of the spinal cord. |
2017-09-07 |
2023-08-13 |
rat |
| Dan Li, Lei Tong, Hitoshi Kawano, Nan Liu, Hong-Jing Yan, Liang Zhao, Hong-Peng L. Regulation and role of ERK phosphorylation in glial cells following a nigrostriatal pathway injury. Brain research. vol 1648. issue Pt A. 2017-08-28. PMID:27402431. |
according to immunofluorescence double staining, it was found that at 4 and 8h after injury, p-erk was expressed in microglia/macrophages, and that more cells were co-expressed by p-erk and iba-1 (microglia/macrophage marker) at 8h; at days 1 and 4, p-erk was expressed in astrocytes, and more cells were co-expressed by p-erk and gfap (astrocyte marker) at day 4. |
2017-08-28 |
2023-08-13 |
mouse |