Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Miranda Brun, Saket Jain, Elizabeth A Monckton, Roseline Godbou. Nuclear Factor I Represses the Notch Effector HEY1 in Glioblastoma. Neoplasia (New York, N.Y.). vol 20. issue 10. 2019-01-28. PMID:30195713. |
knockdown of hey1 resulted in an increase in the rna levels of the gfap astrocyte differentiation marker. |
2019-01-28 |
2023-08-13 |
Not clear |
Alexander Sosunov, Markel Olabarria, James E Goldma. Alexander disease: an astrocytopathy that produces a leukodystrophy. Brain pathology (Zurich, Switzerland). vol 28. issue 3. 2019-01-24. PMID:29740945. |
as other cells in the cns do not express gfap, axd is a primary astrocyte disease. |
2019-01-24 |
2023-08-13 |
Not clear |
Yunan Zhao, Zixuan Lin, Lin Chen, Liufeng Ouyang, Ling Gu, Feiyan Chen, Qiang Zhan. Hippocampal astrocyte atrophy in a mouse depression model induced by corticosterone is reversed by fluoxetine instead of benzodiazepine diazepam. Progress in neuro-psychopharmacology & biological psychiatry. vol 83. 2019-01-03. PMID:29369777. |
in this study, we utilized a repeated corticosterone (cort) injection paradigm to develop a mouse depression model wherein we examined the occurrence of alterations in hippocampal astrocyte population by using two astrocytic markers, namely, glial fibrillary acidic protein (gfap) and s100β. |
2019-01-03 |
2023-08-13 |
mouse |
Hua-Jing Zhang, Ya-Nan Liu, Ping Xian, Jing Ma, Ya-Wen Sun, Jing-Shan Chen, Xi Chen, Nai-Jun Tan. Maternal exposure to TCDD during gestation advanced sensory-motor development, but induced impairments of spatial learning and memory in adult male rat offspring. Chemosphere. vol 212. 2018-12-11. PMID:30176550. |
hippocampus nissl's staining and astrocyte gfap immunohistochemistry were used to evaluate the activity of astrocytes. |
2018-12-11 |
2023-08-13 |
rat |
Ana Carolina Issy, Glauce Crivelaro Nascimento, Gabriel Henrique Dias de Abreu, Fabrine S Tristão, Elaine Del-Bel, Terence Duarte, Mariza Bortolanz. Differential behavioral and glial responses induced by dopaminergic mechanisms in the iNOS knockout mice. Behavioural brain research. vol 350. 2018-11-26. PMID:29751018. |
knowing that inos is mainly expressed in glial cells we analyzed the immunoreactivity (ir) for gfap (astrocyte marker) and iba-1 (microglial marker) in the striatum, an area enrolled in motor planning among other functions. |
2018-11-26 |
2023-08-13 |
mouse |
Kathleen S Curtis, Kelly McCracken, Enith Espinosa, Johnson Ong, Daniel J Buck, Randall L Davi. Temporal and Site-Specific Changes in Central Neuroimmune Factors During Rapid Weight Gain After Ovariectomy in Rats. Neurochemical research. vol 43. issue 9. 2018-11-21. PMID:30030770. |
increased glial fibrillary acidic protein (gfap) expression in the pvn indicated astrocyte activation; decreased toll-like receptor 4 (tlr4) expression in the arc, but not other regions, suggested early effects on innate immune factors. |
2018-11-21 |
2023-08-13 |
rat |
Yusuke Takai, Misato Kawai, Tadashi Ogo, Takashi Ichinose, Shigeki Furuya, Nozomu Takaki, Yukihiro Tone, Hiroshi Udo, Mitsuhiro Furuse, Shinobu Yasu. Early-life Photoperiod Influences Depression-like Behavior, Prepulse Inhibition of the Acoustic Startle Response, and Hippocampal Astrogenesis in Mice. Neuroscience. vol 374. 2018-11-20. PMID:29406270. |
double immunostaining showed that the mice born under sd showed less brdu/glial fibrillary acidic protein (gfap, an astrocyte marker) cells when compared with mice born under ld. |
2018-11-20 |
2023-08-13 |
mouse |
T B Ogassawara, A Joaquim, C P Coelho, M M Bernardi, E Teodorov, M F M Martins, T B Kirsten, L V Bonamin, P D Dossa, L B Viebig, E F Bonda. Food deprivation in F0 generation and hypercaloric diet in F1 generation reduce F2 generation astrogliosis in several brain areas after immune challenge. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 64. 2018-11-15. PMID:28641987. |
also, the astrocyte behavior, after an immune challenge, was examined by the immunohistochemical expression of glial fibrillary acidic protein (gfap) in several brain areas. |
2018-11-15 |
2023-08-13 |
Not clear |
Praveen Kumar, Nachiket M Godbole, Chandra P Chaturvedi, Ravi S Singh, Nelson George, Aditya Upadhyay, B Anjum, Madan M Godbole, Rohit A Sinh. Mechanisms involved in epigenetic down-regulation of Gfap under maternal hypothyroidism. Biochemical and biophysical research communications. vol 502. issue 3. 2018-11-05. PMID:29852171. |
glial fibrillary acidic protein (gfap) is a predominant cell marker of mature astrocyte and is regulated by th status. |
2018-11-05 |
2023-08-13 |
rat |
Ye Ji Jeong, Yeonghoon Son, Na-Kyung Han, Hyung-Do Choi, Jeong-Ki Pack, Nam Kim, Yun-Sil Lee, Hae-June Le. Impact of Long-Term RF-EMF on Oxidative Stress and Neuroinflammation in Aging Brains of C57BL/6 Mice. International journal of molecular sciences. vol 19. issue 7. 2018-10-29. PMID:30029554. |
in addition, levels of markers for dna damage (8-hydroxy-2'-deoxyguanosine, p53, p21, γh2ax, and bax), apoptosis (cleaved caspase-3 and cleaved poly(adp-ribose) polymerase 1 (parp-1)), astrocyte (gfap), and microglia (iba-1) were significantly elevated in the brains of aged mice. |
2018-10-29 |
2023-08-13 |
mouse |
Kozo Saito, Eiji Shigetomi, Rei Yasuda, Ryuichi Sato, Masakazu Nakano, Kei Tashiro, Kenji F Tanaka, Kazuhiro Ikenaka, Katsuhiko Mikoshiba, Ikuko Mizuta, Tomokatsu Yoshida, Masanori Nakagawa, Toshiki Mizuno, Schuichi Koizum. Aberrant astrocyte Ca Glia. vol 66. issue 5. 2018-10-25. PMID:29383757. |
aberrant astrocyte ca alexander disease (axd) is a rare neurodegenerative disorder caused by gain of function mutations in the glial fibrillary acidic protein (gfap) gene. |
2018-10-25 |
2023-08-13 |
Not clear |
Eduardo Fernandes Bondan, Carolina Cardoso Vieira, Maria de Fátima Monteiro Martins, Thiago Berti Kirsten, Maria Martha Bernard. Propentofylline decreases hypothalamic astrogliosis induced by hypercaloric diet in the rat. Arquivos de neuro-psiquiatria. vol 76. issue 4. 2018-10-17. PMID:29742238. |
obesity is associated with a chronic and low-grade inflammatory response in the hypothalamus, where astrogliosis occurs with the upregulation of the astrocyte structural protein gfap. |
2018-10-17 |
2023-08-13 |
rat |
Yeyang Wang, Wenjun Li, Mingsen Wang, Chuangxin Lin, Guitao Li, Xiaozhong Zhou, Junnan Luo, Dadi Ji. Quercetin reduces neural tissue damage and promotes astrocyte activation after spinal cord injury in rats. Journal of cellular biochemistry. vol 119. issue 2. 2018-10-15. PMID:28865131. |
astrocyte activation was assayed by immunohistochemistry staining with an antibody specific for glial fibrillary acidic protein (gfap), as well as the expression of gfap and s100β. |
2018-10-15 |
2023-08-13 |
rat |
Yazmin M Flores-Martinez, Manuel A Fernandez-Parrilla, Jose Ayala-Davila, David Reyes-Corona, Victor M Blanco-Alvarez, Luis O Soto-Rojas, Claudia Luna-Herrera, Juan A Gonzalez-Barrios, Bertha A Leon-Chavez, Maria E Gutierrez-Castillo, Irma A Martínez-Dávila, Daniel Martinez-Fon. Acute Neuroinflammatory Response in the Substantia Nigra Pars Compacta of Rats after a Local Injection of Lipopolysaccharide. Journal of immunology research. vol 2018. 2018-10-11. PMID:29854828. |
lps induced fever, sickness behavior, and microglial activation (ox42 immunoreactivity), followed by astrocyte activation and leukocyte infiltration (gfap and cd45 immunoreactivities). |
2018-10-11 |
2023-08-13 |
rat |
Hongsheng Jiang, Yanzhou Wang, Xin Liang, Xiaofeng Xing, Xiuzhen Xu, Caifeng Zho. Toll-Like Receptor 4 Knockdown Attenuates Brain Damage and Neuroinflammation After Traumatic Brain Injury via Inhibiting Neuronal Autophagy and Astrocyte Activation. Cellular and molecular neurobiology. vol 38. issue 5. 2018-10-05. PMID:29222622. |
furthermore, tlr4 silencing markedly suppressed gfap upregulation and improved cell hypertrophy to attenuate tbi-induced astrocyte activation. |
2018-10-05 |
2023-08-13 |
rat |
Amy B Parsons-White, Nadja Spitze. Environmentally relevant manganese overexposure alters neural cell morphology and differentiation in vitro. Toxicology in vitro : an international journal published in association with BIBRA. vol 50. 2018-10-01. PMID:29486219. |
in addition, mn overexposure caused downregulation of dcx, a neuronal migration marker, and gfap, a neural stem cell and astrocyte marker, in nscs. |
2018-10-01 |
2023-08-13 |
rat |
Yolanda de Pablo, Meng Chen, Elin Möllerström, Marcela Pekna, Milos Pekn. Drugs targeting intermediate filaments can improve neurosupportive properties of astrocytes. Brain research bulletin. vol 136. 2018-08-30. PMID:28159699. |
clomipramine decreased protein levels of gfap, as well as vimentin and nestin, and did not affect astrocyte resilience to oxidative stress. |
2018-08-30 |
2023-08-13 |
Not clear |
Beatrice Bedussi, Daphne M P Naessens, Judith de Vos, Rik Olde Engberink, Micha M M Wilhelmus, Edo Richard, Malyssa Ten Hove, Ed vanBavel, Erik N T P Bakke. Enhanced interstitial fluid drainage in the hippocampus of spontaneously hypertensive rats. Scientific reports. vol 7. issue 1. 2018-08-30. PMID:28389645. |
these locations stained positively for the astrocyte marker gfap, and aquaporin 4. |
2018-08-30 |
2023-08-13 |
rat |
Peng Liu, Rui Zhang, Danyang Liu, Jinling Wang, Chunling Yuan, Xuemei Zhao, Yinjie Li, Xuefei Ji, Tianyan Chi, Libo Zo. Time-course investigation of blood-brain barrier permeability and tight junction protein changes in a rat model of permanent focal ischemia. The journal of physiological sciences : JPS. vol 68. issue 2. 2018-08-13. PMID:28078626. |
gfap, an astrocyte marker, gradually increased in the cortex penumbra over time post-ischemia. |
2018-08-13 |
2023-08-13 |
human |
Li-Hsien Lin, Susan Jones, William T Talma. Cellular Localization of Acid-Sensing Ion Channel 1 in Rat Nucleus Tractus Solitarii. Cellular and molecular neurobiology. vol 38. issue 1. 2018-08-13. PMID:28825196. |
in control tissue, asic1-ir predominantly colocalized with ir for the astrocyte marker, glial fibrillary acidic protein (gfap), or the microglial marker, integrin αm (ox42). |
2018-08-13 |
2023-08-13 |
rat |