| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Devi Rani Sagar, James J Burston, Gareth J Hathway, Stephen G Woodhams, Richard G Pearson, Andrew J Bennett, David A Kendall, Brigitte E Scammell, Victoria Chapma. The contribution of spinal glial cells to chronic pain behaviour in the monosodium iodoacetate model of osteoarthritic pain. Molecular pain. vol 7. 2012-08-06. PMID:22093915. |
spinal cord microglia (iba1 staining) and astrocyte (gfap immunofluorescence) activation were measured at 7, 14 and 28 days post mia-treatment. |
2012-08-06 |
2023-08-12 |
rat |
| Jeannine C Foley, Sally R McIver, Philip G Haydo. Gliotransmission modulates baseline mechanical nociception. Molecular pain. vol 7. 2012-08-06. PMID:22136202. |
under baseline conditions, immunostaining in the dorsal horn of the spinal cord showed astrocyte-specific transgene expression in dnsnare mice, and no difference in expression levels of the astrocyte marker gfap and the microglia marker iba1 relative to wild-type mice. |
2012-08-06 |
2023-08-12 |
mouse |
| Sheng-Chin Kao, Xiuli Zhao, Chun-Yi Lee, Fidelis E Atianjoh, Estelle B Gauda, Myron Yaster, Yuan-Xiang Ta. Absence of μ opioid receptor mRNA expression in astrocytes and microglia of rat spinal cord. Neuroreport. vol 23. issue 6. 2012-08-01. PMID:22362187. |
in the present study, by combining the techniques of in-situ hybridization of mor mrna with immunohistochemistry of glial fibrillary acidic protein (gfap; an astrocyte marker) and iba1 (a microglial marker), we examined expression and distribution of gfap, iba1, and mor mrna in the spinal cord of rats under chronic morphine tolerance conditions. |
2012-08-01 |
2023-08-12 |
rat |
| Masamitsu Shimazawa, Yasushi Ito, Yuta Inokuchi, Hajime Yamanaka, Tomohiro Nakanishi, Takuya Hayashi, Bin Ji, Makoto Higuchi, Tetsuya Suhara, Kazuyuki Imamura, Makoto Araie, Yasuyoshi Watanabe, Hirotaka Onoe, Hideaki Har. An alteration in the lateral geniculate nucleus of experimental glaucoma monkeys: in vivo positron emission tomography imaging of glial activation. PloS one. vol 7. issue 1. 2012-07-05. PMID:22299044. |
at mild, moderate, and advanced experimental glaucoma stages (classified by histological changes based on the extent of axonal loss), brains were stained with cresyl violet, or antibodies against pbr, iba-1 (a microglial marker), and gfap (an activated astrocyte marker). |
2012-07-05 |
2023-08-12 |
monkey |
| Ellen M Andrews, Rebekah J Richards, Feng Q Yin, Mariano S Viapiano, Lyn B Jakema. Alterations in chondroitin sulfate proteoglycan expression occur both at and far from the site of spinal contusion injury. Experimental neurology. vol 235. issue 1. 2012-06-29. PMID:21952042. |
gfap antibodies revealed a transient increase in reactive astrocyte staining in cervical and lumbar cord, peaking at 14 dpi. |
2012-06-29 |
2023-08-12 |
Not clear |
| Xiaoyuan Mao, Changwei Ji, Chunyan Sun, Danfeng Cao, Ping Ma, Zhong Ji, Fangyuan Cao, Dongyu Min, Shuzhi Li, Jiqun Cai, Yonggang Ca. Topiramate attenuates cerebral ischemia/reperfusion injury in gerbils via activating GABAergic signaling and inhibiting astrogliosis. Neurochemistry international. vol 60. issue 1. 2012-06-20. PMID:22085431. |
in addition, the fluorescent intensity and protein level of glial fibrillary acidic protein (gfap), a major component of astrocyte, were examined by confocal and immunoblot analysis. |
2012-06-20 |
2023-08-12 |
Not clear |
| Yue-Mao Zheng, Yan-Ling Zheng, Xiao-Ying He, Xiao-Ning He, Xue Zhao, Wu-Jia-Fu Sa. Multipotent differentiation of the EGFP gene transgenic stem cells derived from amniotic fluid of goat at terminal gestational age. Cell biology international. vol 35. issue 12. 2012-06-06. PMID:21605083. |
afs cells were positive for the undifferentiated cell markers, oct4, nanog, sox2 and hes1, while following differentiation cells expressed markers for neurogenic cells such as astrocyte [gfap (glial fibrillary acidic protein)] and nse (neuron-specific enolase), adipogenic cells [lpl+ (lipoprotein lipase+)], osteogenic cells (osteocalcin+ and osteonectin+) and endothelium [cd34+ and enos+ (endothelial nitric oxide synthase)]. |
2012-06-06 |
2023-08-12 |
Not clear |
| Tin-Tin Win-Shwe, Naoki Kunugita, Yasuhiro Yoshida, Daisuke Nakajima, Shinji Tsukahara, Hidekazu Fujimak. Differential mRNA expression of neuroimmune markers in the hippocampus of infant mice following toluene exposure during brain developmental period. Journal of applied toxicology : JAT. vol 32. issue 2. 2012-05-23. PMID:21381054. |
in contrast, ngf and brain-derived neurotrophic factor (bdnf) and proinflammatory cytokines tnf-α, ccl3, nf-κb, toll-like receptor (tlr)-4, astrocyte marker glial fibrillary acidic protein (gfap), and microglia marker ionized calcium binding adapter molecule (iba)-1 mrnas were increased significantly in mice exposed to 5 ppm toluene on pnd 8-12. |
2012-05-23 |
2023-08-12 |
mouse |
| Bruno P S Pitanga, Victor Diógenes A Silva, Cleide S Souza, Huiara A Junqueira, Breno O N Fragomeni, Ravena P Nascimento, Ana Rita Silva, Maria de Fátima D Costa, Ramon S El-Bachá, Silvia L Cost. Assessment of neurotoxicity of monocrotaline, an alkaloid extracted from Crotalaria retusa in astrocyte/neuron co-culture system. Neurotoxicology. vol 32. issue 6. 2012-05-02. PMID:21781985. |
previously we demonstrated that both mct and dehydromonocrotaline (dhmc), its main active metabolite, induce changes in the levels and patterns of expression of the main protein from astrocyte cytoskeleton, glial fibrillary acidic protein (gfap). |
2012-05-02 |
2023-08-12 |
rat |
| Pamela J Vandevord, Richard Bolander, Venkata Siva Sai Sujith Sajja, Kathryn Hay, Cynthia A Bi. Mild neurotrauma indicates a range-specific pressure response to low level shock wave exposure. Annals of biomedical engineering. vol 40. issue 1. 2012-04-24. PMID:21994066. |
histological parameters included measuring the levels of glial fibrillary acidic protein (gfap) to identify astrocyte activation, cleaved caspase-3 for early apoptosis identification and fluoro-jade b (fjb) which labels degenerating neurons within the brain tissue. |
2012-04-24 |
2023-08-12 |
rat |
| Alexander Ternianov, José M Pérez-Ortiz, María E Solesio, María S García-Gutiérrez, Antonio Ortega-Álvaro, Francisco Navarrete, Carlos Leiva, María F Galindo, Jorge Manzanare. Overexpression of CB2 cannabinoid receptors results in neuroprotection against behavioral and neurochemical alterations induced by intracaudate administration of 6-hydroxydopamine. Neurobiology of aging. vol 33. issue 2. 2012-04-19. PMID:20980074. |
gfap and iba-1 immunostaining revealed less astrocyte and microglia recruitment to the treated area of the cpu in cb2xp mice. |
2012-04-19 |
2023-08-12 |
mouse |
| Dhiraj Maskey, Hye-Jin Kim, Hyung Gun Kim, Myeung Ju Ki. Calcium-binding proteins and GFAP immunoreactivity alterations in murine hippocampus after 1 month of exposure to 835 MHz radiofrequency at SAR values of 1.6 and 4.0 W/kg. Neuroscience letters. vol 506. issue 2. 2012-04-19. PMID:22133805. |
decrement in the cabps can affect the calcium-buffering capacity leading to cell death, while increased gfap ir and changes in astrocyte morphology, may mediate brain injury due to radiofrequency exposure. |
2012-04-19 |
2023-08-12 |
Not clear |
| Dong Jo Chang, Mi Young Jeong, Jiho Song, Chang Yun Jin, Young-Ger Suh, Hyun-Jung Kim, Kyung Hoon Mi. Discovery of small molecules that enhance astrocyte differentiation in rat fetal neural stem cells. Bioorganic & medicinal chemistry letters. vol 21. issue 23. 2012-04-18. PMID:22001087. |
differentiation activity was assessed by immunocytochemistry and analysis of mrna expression of astrocyte markers, gfap and s100. |
2012-04-18 |
2023-08-12 |
rat |
| Fu-Sun Lo, Shuxin Zhao, Reha S Erzuruml. Astrocytes promote peripheral nerve injury-induced reactive synaptogenesis in the neonatal CNS. Journal of neurophysiology. vol 106. issue 6. 2012-04-16. PMID:21900512. |
astrocyte proliferation and upregulation of astrocyte-specific proteins (gfap and aldh1l1) accompany reactive synaptogenesis in the io nerve projection zone of the prv. |
2012-04-16 |
2023-08-12 |
rat |
| Minfeng Shu, Yuehan Zhou, Wenbo Zhu, Haipeng Zhang, Sihan Wu, Jingkao Chen, Guangmei Ya. MicroRNA 335 is required for differentiation of malignant glioma cells induced by activation of cAMP/protein kinase A pathway. Molecular pharmacology. vol 81. issue 3. 2012-04-11. PMID:22172575. |
we have reported previously that activation of camp/protein kinase a (pka) pathway is capable of inducing glioma cell differentiation, characterized by astrocyte-like shape and dramatic induction of astrocyte biomarker glial fibrillary acidic protein (gfap). |
2012-04-11 |
2023-08-12 |
human |
| Xiaoyuan Mao, Ping Ma, Danfeng Cao, Chunyan Sun, Zhong Ji, Dongyu Min, Hongli Sun, Ni Xie, Jiqun Cai, Yonggang Ca. Altered expression of GABAA receptors (α4, γ2 subunit), potassium chloride cotransporter 2 and astrogliosis in tremor rat hippocampus. Brain research bulletin. vol 86. issue 5-6. 2012-04-05. PMID:21924329. |
besides, our present study also demonstrated that gfap (a major component of astrocyte) immunoreactivity was much more intense in trms hippocampal ca1, ca3 and dg regions than that in control group with immnohistochemistry and confocal microscopic analyses. |
2012-04-05 |
2023-08-12 |
rat |
| Ina-Beate Wanne. An in vitro trauma model to study rodent and human astrocyte reactivity. Methods in molecular biology (Clifton, N.J.). vol 814. 2012-03-27. PMID:22144309. |
prototypical astrocyte proteins including gfap, s100, aquaporin4, glutamate transporters, and tenascin are expressed in mouse, rat, and human in vitro matured astrocyte. |
2012-03-27 |
2023-08-12 |
mouse |
| D Domenger, D Dea, L Theroux, L Moquin, A Gratton, J Poirie. The MPTP neurotoxic lesion model of Parkinson's disease activates the apolipoprotein E cascade in the mouse brain. Experimental neurology. vol 233. issue 1. 2012-03-25. PMID:22155743. |
we examined the modifications in gene expression and protein levels of apoe and its key receptors, the low density lipoprotein receptor (ldlr) and the ldlr-related protein (lrp), as well as the reactive astrocyte marker glial fibrillary acidic protein (gfap) in different brain structures throughout the degenerative and reactive regenerative period. |
2012-03-25 |
2023-08-12 |
mouse |
| Ali Ghoochani, Khadijeh Shabani, Maryam Peymani, Kamran Ghaedi, Fereshteh Karamali, Khadijeh Karbalaei, Somayeh Tanhaie, Ahmad Salamian, Abolghasem Esmaeili, Sadegh Valian-Borujeni, Mehrdad Hashemi, Mohammad Hossein Nasr-Esfahani, Hossein Baharvan. The influence of peroxisome proliferator-activated receptor γ(1) during differentiation of mouse embryonic stem cells to neural cells. Differentiation; research in biological diversity. vol 83. issue 1. 2012-03-20. PMID:22099177. |
however, pparγ inactivation by antagonist treatment post-nps formation stage only decreased the expression of mature astrocyte marker (gfap) suggesting that inactivation of pparγ by antagonist decreased astrocyte differentiation. |
2012-03-20 |
2023-08-12 |
mouse |
| Cynthia H Kern, Donald R Smit. Preweaning Mn exposure leads to prolonged astrocyte activation and lasting effects on the dopaminergic system in adult male rats. Synapse (New York, N.Y.). vol 65. issue 6. 2012-03-12. PMID:20963817. |
to determine if early mn exposure produces lasting neurobehavioral and neurochemical effects, we treated neonate rats with oral mn (0, 25, or 50 mg mn/kg/d over pnd 1-21) and evaluated (1) behavioral performance in the open arena in the absence (pnd 97) and presence (pnd 98) of a d-amphetamine challenge, (2) brain dopamine d1 and d2-like receptors and dopamine transporter densities in the prefrontal cortex, striatum, and nucleus accumbens (pnd 107), and (3) astrocyte marker glial fibrillary acidic protein (gfap) levels in these same brain regions (pnd 24 and 107). |
2012-03-12 |
2023-08-12 |
rat |