Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Hao Yang, Zhe Liang, Jingwen Li, Xiping Cheng, Na Luo, Gong J. Optimized and efficient preparation of astrocyte cultures from rat spinal cord. Cytotechnology. vol 52. issue 2. 2011-07-14. PMID:19002867. |
using immunofluorescent antibodies against gfap and ox-42 in combination of hoechst 33342 fluorescent staining, we found that the purity of the astrocyte cultures was >99%. |
2011-07-14 |
2023-08-12 |
rat |
Yan-Qing Zhang, Xiang Zeng, Liu-Min He, Ying Ding, Yan Li, Yuan-Shan Zen. NT-3 gene modified Schwann cells promote TrkC gene modified mesenchymal stem cells to differentiate into neuron-like cells in vitro. Anatomical science international. vol 85. issue 2. 2011-07-14. PMID:19680743. |
however, the expression of glial fibrillary acidic protein (gfap)--an astrocyte marker in these cells--was not so obvious. |
2011-07-14 |
2023-08-12 |
human |
Gehan H Fahmy, Marie Z Mofta. Fgf-2 in astroglial cells during vertebrate spinal cord recovery. Frontiers in cellular neuroscience. vol 4. 2011-07-14. PMID:21119776. |
a key indicator of astrocyte activation is the increased accumulation of intermediate filaments composed of glial fibrillary acidic protein (gfap). |
2011-07-14 |
2023-08-12 |
Not clear |
N Xiong, Z Zhang, J Huang, C Chen, Z Zhang, M Jia, J Xiong, X Liu, F Wang, X Cao, Z Liang, S Sun, Z Lin, T Wan. VEGF-expressing human umbilical cord mesenchymal stem cells, an improved therapy strategy for Parkinson's disease. Gene therapy. vol 18. issue 4. 2011-07-08. PMID:21107440. |
as a result, humscs differentiated into dopaminergic neuron-like cells on the basis of neuron-specific enolase (nse) (neuronal marker), glial fibrillary acidic protein (gfap) (astrocyte marker), nestin (neural stem cell marker) and tyrosine hydroxylase (th) (dopaminergic marker) expression. |
2011-07-08 |
2023-08-12 |
human |
J Middeldorp, E M Ho. GFAP in health and disease. Progress in neurobiology. vol 93. issue 3. 2011-06-17. PMID:21219963. |
major recent developments in astrocyte biology and the discovery of novel intermediate filament functions enticed the interest in the function of gfap. |
2011-06-17 |
2023-08-12 |
human |
J Middeldorp, E M Ho. GFAP in health and disease. Progress in neurobiology. vol 93. issue 3. 2011-06-17. PMID:21219963. |
the structural role of gfap in astrocytes has been widely accepted for a long time, but over the years, gfap has been shown to be involved in astrocyte functions, which are important during regeneration, synaptic plasticity and reactive gliosis. |
2011-06-17 |
2023-08-12 |
human |
Jane Kasten-Jolly, Yong Heo, David A Lawrenc. Central nervous system cytokine gene expression: modulation by lead. Journal of biochemical and molecular toxicology. vol 25. issue 1. 2011-05-27. PMID:21322097. |
il-6 and tgf-β1 both have signal transduction cascades that can cooperatively turn on the gene for the astrocyte marker glial-fibrillary acidic protein (gfap). |
2011-05-27 |
2023-08-12 |
mouse |
Yan Liu, Hui Zhu, Mei Liu, Jinfeng Du, Yuyan Qian, Yongjun Wang, Fei Ding, Xiaosong G. Downregulation of Pax3 expression correlates with acquired GFAP expression during NSC differentiation towards astrocytes. FEBS letters. vol 585. issue 7. 2011-05-26. PMID:21371476. |
in the present study, we reported paired box 3 protein (pax3) as a novel regulator of gfap transcription, which could bind the promoter region of gfap and down regulate the gfap level during the serum-induced astrocyte differentiation of neural stem cells (nscs). |
2011-05-26 |
2023-08-12 |
Not clear |
Yan Liu, Hui Zhu, Mei Liu, Jinfeng Du, Yuyan Qian, Yongjun Wang, Fei Ding, Xiaosong G. Downregulation of Pax3 expression correlates with acquired GFAP expression during NSC differentiation towards astrocytes. FEBS letters. vol 585. issue 7. 2011-05-26. PMID:21371476. |
these data suggest that pax3 negatively regulates gfap expression during astrocyte differentiation in vitro. |
2011-05-26 |
2023-08-12 |
Not clear |
Esperanza García, Juana Villeda-Hernández, José Pedraza-Chaverrí, Perla D Maldonado, Abel Santamarí. S-allylcysteine reduces the MPTP-induced striatal cell damage via inhibition of pro-inflammatory cytokine tumor necrosis factor-α and inducible nitric oxide synthase expressions in mice. Phytomedicine : international journal of phytotherapy and phytopharmacology. vol 18. issue 1. 2011-05-24. PMID:20576415. |
in this work we investigated whether sac can protect the striatum of mice from the morphological alterations in the mptp toxic model, and if this response is correlated with a reduction in pro-inflammatory cytokine tumor necrosis factor-α (tnf-α) and inducible nitric oxide synthase (inos) expressions, and further reduction in astrocyte activation (glial fibrillary acidic protein (gfap) expression). |
2011-05-24 |
2023-08-12 |
mouse |
Yea-Hyun Leem, Young-Ik Lee, Hee-Jeong Son, Sang-Ho Le. Chronic exercise ameliorates the neuroinflammation in mice carrying NSE/htau23. Biochemical and biophysical research communications. vol 406. issue 3. 2011-05-12. PMID:21329662. |
the brains of tg mice exhibited increased immunoreactivity and active morphological changes in gfap (astrocyte marker) and mac-1 (microglia marker) expression in an age-dependent manner. |
2011-05-12 |
2023-08-12 |
mouse |
E G Gilerovich, E A Fedorova, I N Abdurasulova, M N Karpenko, A V Sokolov, E T Zakharova, Iu L Zhitnukhin, D É Korzhevskiĭ, V B Vasil'e. [Analysis of morphological manifestations of the inflammatory reaction in wistar rat spinal cord in experimental model]. Morfologiia (Saint Petersburg, Russia). vol 137. issue 5. 2011-05-12. PMID:21500426. |
distribution of proliferating cell nuclear antigen (pcna), astrocyte marker - glial fibrillar acidic protein (gfap), and microglia and macrophage marker iba-1, was studied. |
2011-05-12 |
2023-08-12 |
rat |
Sandeep K Singh, Katarzyna M Wilczynska, Adrian Grzybowski, Jessie Yester, Bahiya Osrah, Lauren Bryan, Sarah Wright, Irene Griswold-Prenner, Tomasz Kordul. The unique transcriptional activation domain of nuclear factor-I-X3 is critical to specifically induce marker gene expression in astrocytes. The Journal of biological chemistry. vol 286. issue 9. 2011-05-04. PMID:21189253. |
the expression of nfi-x3 is dramatically up-regulated during the differentiation of neural progenitors to astrocytes and precedes the expression of astrocyte markers, such as gfap and sparcl1 (secreted protein, acidic and rich in cysteines-like 1). |
2011-05-04 |
2023-08-12 |
human |
V Bramanti, D Tomassoni, D Bronzi, S Grasso, M Currò, M Avitabile, G Li Volsi, M Renis, R Ientile, F Amenta, R Avol. Alpha-lipoic acid modulates GFAP, vimentin, nestin, cyclin D1 and MAP-kinase expression in astroglial cell cultures. Neurochemical research. vol 35. issue 12. 2011-04-28. PMID:20814740. |
alpha-lipoic acid modulates gfap, vimentin, nestin, cyclin d1 and map-kinase expression in astroglial cell cultures. |
2011-04-28 |
2023-08-12 |
Not clear |
Letícia Rodrigues, Márcio Ferreira Dutra, Jocemar Ilha, Regina Biasibetti, André Quincozes-Santos, Marina C Leite, Simone Marcuzzo, Matilde Achaval, Carlos-Alberto Gonçalve. Treadmill training restores spatial cognitive deficits and neurochemical alterations in the hippocampus of rats submitted to an intracerebroventricular administration of streptozotocin. Journal of neural transmission (Vienna, Austria : 1996). vol 117. issue 11. 2011-03-21. PMID:20953641. |
this study aimed to evaluate the effect of 5-week treadmill training, in the icv-szt model of sporadic ad, on cognitive function, oxidative stress (particularly mediated by no) and on the astrocyte marker proteins, glial fibrillary acidic protein (gfap) and s100b. |
2011-03-21 |
2023-08-12 |
human |
Deqiang Lei, Hongyang Zhao, Xingli Deng, Ruen Liu, Fangcheng Zhang, Dongxiao Ya. Superparamagnetic iron oxide labeling of spinal cord neural stem cells genetically modified by nerve growth factor-beta. Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban. vol 29. issue 2. 2011-03-17. PMID:19399412. |
the distinctive markers for stem cells (nestin), neuron (beta-iii-tubulin), oligodendrocyte (cnpase) and astrocyte (gfap) were employed to evaluate the differentiation ability of the labeled cells. |
2011-03-17 |
2023-08-12 |
rat |
Louis Doré-Savard, Valérie Otis, Karine Belleville, Myriam Lemire, Mélanie Archambault, Luc Tremblay, Jean-François Beaudoin, Nicolas Beaudet, Roger Lecomte, Martin Lepage, Louis Gendron, Philippe Sarre. Behavioral, medical imaging and histopathological features of a new rat model of bone cancer pain. PloS one. vol 5. issue 10. 2011-03-07. PMID:21048940. |
bone remodeling was accompanied by c-fos (spinal) and atf3 (drg) neuronal activation, sustained by astrocyte (gfap) and microglia (iba1) reactivity in lumbar spinal cord. |
2011-03-07 |
2023-08-12 |
human |
Britta Wachter, Sonja Schürger, Jens Rolinger, Andreas von Ameln-Mayerhofer, Daniela Berg, Hans-Jochen Wagner, Eva Kuepper. Effect of 6-hydroxydopamine (6-OHDA) on proliferation of glial cells in the rat cortex and striatum: evidence for de-differentiation of resident astrocytes. Cell and tissue research. vol 342. issue 2. 2011-03-03. PMID:20976472. |
it is characterized by cellular hypertrophy, up-regulation of the astrocyte marker glial fibrillary acidic protein (gfap), and proliferation. |
2011-03-03 |
2023-08-12 |
rat |
Henrik Toft-Hansen, Laila Füchtbauer, Trevor Owen. Inhibition of reactive astrocytosis in established experimental autoimmune encephalomyelitis favors infiltration by myeloid cells over T cells and enhances severity of disease. Glia. vol 59. issue 1. 2011-02-25. PMID:21046558. |
although aquaporin-4 staining on astrocyte endfeet at the glia limitans remained equally detectable, gfap immunoreactivity and mrna expression in cns were reduced by this treatment. |
2011-02-25 |
2023-08-12 |
mouse |
Dong Hyun Kim, Won Young Jung, Se Jin Park, Jong Min Kim, Seungjoo Lee, Young Choong Kim, Jong Hoon Ry. Anti-amnesic effect of ESP-102 on Aβ(1-42)-induced memory impairment in mice. Pharmacology, biochemistry, and behavior. vol 97. issue 2. 2011-02-03. PMID:20728465. |
aβ(1-42)-induced increases in the expression of gfap (an astrocyte marker) and inducible nitric oxide synthase (inos) in the hippocampal region were also attenuated by esp-102 treatment. |
2011-02-03 |
2023-08-12 |
mouse |