| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ling-Hui Zeng, Adam W Bero, Bo Zhang, David M Holtzman, Michael Won. Modulation of astrocyte glutamate transporters decreases seizures in a mouse model of Tuberous Sclerosis Complex. Neurobiology of disease. vol 37. issue 3. 2010-06-08. PMID:20045054. |
in particular, decreased expression and function of astrocyte glutamate transporters have been implicated in causing elevated extracellular glutamate levels, neuronal death, and epilepsy in a mouse model of tsc (tsc1(gfap)cko mice), involving inactivation of the tsc1 gene primarily in astrocytes. |
2010-06-08 |
2023-08-12 |
mouse |
| Ling-Hui Zeng, Adam W Bero, Bo Zhang, David M Holtzman, Michael Won. Modulation of astrocyte glutamate transporters decreases seizures in a mouse model of Tuberous Sclerosis Complex. Neurobiology of disease. vol 37. issue 3. 2010-06-08. PMID:20045054. |
here, we tested whether pharmacological induction of astrocyte glutamate transporter expression can prevent the neurological phenotype of tsc1(gfap)cko mice. |
2010-06-08 |
2023-08-12 |
mouse |
| Ling-Hui Zeng, Adam W Bero, Bo Zhang, David M Holtzman, Michael Won. Modulation of astrocyte glutamate transporters decreases seizures in a mouse model of Tuberous Sclerosis Complex. Neurobiology of disease. vol 37. issue 3. 2010-06-08. PMID:20045054. |
early treatment with ceftriaxone prior to the onset of epilepsy increased expression of astrocyte glutamate transporters, decreased extracellular glutamate levels, neuronal death, and seizure frequency, and improved survival in tsc1(gfap)cko mice. |
2010-06-08 |
2023-08-12 |
mouse |
| Ling-Hui Zeng, Adam W Bero, Bo Zhang, David M Holtzman, Michael Won. Modulation of astrocyte glutamate transporters decreases seizures in a mouse model of Tuberous Sclerosis Complex. Neurobiology of disease. vol 37. issue 3. 2010-06-08. PMID:20045054. |
these results indicate that astrocyte glutamate transporters contribute to epileptogenesis in tsc1(gfap)cko mice and suggest novel therapeutic strategies for epilepsy in tsc directed at astrocytes. |
2010-06-08 |
2023-08-12 |
mouse |
| Susan M Sullivan, S Tracey Björkman, Stephanie M Miller, Paul B Colditz, David V Po. Morphological changes in white matter astrocytes in response to hypoxia/ischemia in the neonatal pig. Brain research. vol 1319. 2010-06-07. PMID:20079338. |
this loss of gfap was accompanied by alterations in astrocyte morphology and an overall decrease in the size (field of section occupied by an individual astrocyte) of white matter astrocytes from 649microm(2) to 426microm(2), as revealed by golgi-kopsch staining and image analysis. |
2010-06-07 |
2023-08-12 |
human |
| Jing-Ge Zhang, Shu-Qing Li, Shu-Ren Wang, Fan L. [The effect of ginkgolide B on astrocyte GFAP expression after the focal cerebral ischemia]. Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition. vol 38. issue 2. 2010-06-02. PMID:17441350. |
[the effect of ginkgolide b on astrocyte gfap expression after the focal cerebral ischemia]. |
2010-06-02 |
2023-08-12 |
Not clear |
| S G Temel, Z Kahvec. Cyclooxygenase-2 expression in astrocytes and microglia in human oligodendroglioma and astrocytoma. Journal of molecular histology. vol 40. issue 5-6. 2010-06-02. PMID:20052522. |
for this purpose we employed dual immunohistochemistry for cox-2 and gfap (astrocyte) or lca-mac (microglia-macrophage) in archival formalin-fixed, paraffin embedded human tissue diagnosed as oligodendroglioma and/or astrocytoma. |
2010-06-02 |
2023-08-12 |
human |
| Osamu Kitamura, Toshiaki Takeichi, Elaine Lu Wang, Itsuo Tokunaga, Akiko Ishigami, Shin-ichi Kub. Microglial and astrocytic changes in the striatum of methamphetamine abusers. Legal medicine (Tokyo, Japan). vol 12. issue 2. 2010-06-02. PMID:20110187. |
glial fibrillary acidic protein (gfap) and s100 beta were used for astrocyte immunohistochemistry. |
2010-06-02 |
2023-08-12 |
human |
| Robin E White, Dana M McTigue, Lyn B Jakema. Regional heterogeneity in astrocyte responses following contusive spinal cord injury in mice. The Journal of comparative neurology. vol 518. issue 8. 2010-06-01. PMID:20151365. |
bromodeoxyuridine (brdu) was administered to mice 3 days after sci, and cells expressing brdu and the astrocyte marker, glial fibrillary acidic protein (gfap), were counted at 3, 7, and 49 days post-injury (dpi). |
2010-06-01 |
2023-08-12 |
mouse |
| Jinte Middeldorp, Simone A van den Berge, Eleonora Aronica, Dave Speijer, Elly M Ho. Specific human astrocyte subtype revealed by affinity purified GFAP antibody; unpurified serum cross-reacts with neurofilament-L in Alzheimer. PloS one. vol 4. issue 11. 2010-04-26. PMID:19888461. |
specific human astrocyte subtype revealed by affinity purified gfap antibody; unpurified serum cross-reacts with neurofilament-l in alzheimer. |
2010-04-26 |
2023-08-12 |
human |
| Jiann-Jy Chen, June-Horng Lue, Lung-Huang Lin, Chun-Ta Huang, Rayleigh Ping-Ying Chiang, Chih-Li Chen, Yi-Ju Tsa. Effects of pre-emptive drug treatment on astrocyte activation in the cuneate nucleus following rat median nerve injury. Pain. vol 148. issue 1. 2010-04-07. PMID:19954890. |
using immunohistochemistry and immunoblotting, little glial fibrillary acidic protein (gfap; an astrocyte marker) immunoreactivity was detected in the cn of the normal rats. |
2010-04-07 |
2023-08-12 |
rat |
| Nina Mani, Alfia Khaibullina, Janette M Krum, Jeffrey M Rosenstei. Vascular endothelial growth factor enhances migration of astroglial cells in subventricular zone neurosphere cultures. Journal of neuroscience research. vol 88. issue 2. 2010-03-30. PMID:19705456. |
our data indicate that vegf administration, compared with untreated or brain-derived neurotrophic factor-treated ns, significantly increased growth and migratory capacity of glial fibrillary acidic protein (gfap)(+) and nestin(+) nsp cells and in secondary cultures induced a stellate astrocyte morphology. |
2010-03-30 |
2023-08-12 |
Not clear |
| Tânia Cristina Leite de Sampaio e Spohr, Joice Stipursky, Adriana Campos Sasaki, Pedro Rocha Barbosa, Vanessa Martins, Cláudia Farias Benjamim, Nidia Franca Roque, Sílvia Lima Costa, Flávia Carvalho Alcantara Gome. Effects of the flavonoid casticin from Brazilian Croton betulaster in cerebral cortical progenitors in vitro: direct and indirect action through astrocytes. Journal of neuroscience research. vol 88. issue 3. 2010-03-30. PMID:19746423. |
pools of astrocyte (gfap and s100beta), neural (nestin), and oligodendrocyte (olig2 and ng2) progenitors were not affected by casticin. |
2010-03-30 |
2023-08-12 |
rat |
| Yue-Mao Zheng, Zhi-Xing An, Xiao-E Zhao, Fu-Sheng Quan, Hui-Ying Zhao, Ya-Rong Zhang, Jun Liu, Xiao-Ying He, Xiao-Ning H. Comparation of enhanced green fluorescent protein gene transfected and wild-type porcine neural stem cells. Research in veterinary science. vol 88. issue 1. 2010-03-22. PMID:19580981. |
nscs could differentiated into astrocyte (gfap(+)), oligodendrocyte (galc(+)), neuron (nf(+), nse(+) and map2(+)) and myocyte (myf-6(+) and myod(+)). |
2010-03-22 |
2023-08-12 |
Not clear |
| M-S Kwon, Y-J Seo, S-M Choi, M-H Won, J-K Lee, S-H Park, J-S Jung, Y-B Sim, H-W Su. The time-dependent effect of lipopolysaccharide on kainic acid-induced neuronal death in hippocampal CA3 region: possible involvement of cytokines via glucocorticoid. Neuroscience. vol 165. issue 4. 2010-03-12. PMID:19961903. |
in addition, ru38486 (glucocorticoid receptor antagonist) decreased the hippocampal il-1beta mrna level and abolished the aggravating effect of lps on ka-induced neuronal death at lps 90 min and 24 h. in the immunohistochemical study, we found activated and ramified microglia (ox-42) and astrocyte (gfap) at 24 h after lps treatment (lps 24 h) in the hippocampus. |
2010-03-12 |
2023-08-12 |
mouse |
| Feng Jiang, Tong Liu, Ming Cheng, Xue-Yan Pang, Zhan-Tao Bai, Jing-Jing Zhou, Yong-Hua J. Spinal astrocyte and microglial activation contributes to rat pain-related behaviors induced by the venom of scorpion Buthus martensi Karch. European journal of pharmacology. vol 623. issue 1-3. 2010-02-22. PMID:19782067. |
the results showed that glial fibrillary acidic protein (gfap) immunoreactivity indicative astrocyte activation in bilateral spinal cord started to increase by day 3, peaked at day 7 and gradually reversed at day 14 following intraplantar injection of bmk venom. |
2010-02-22 |
2023-08-12 |
rat |
| Justin D Lathia, Srinivasulu Chigurupati, John Thundyil, Pradeep K Selvaraj, Mohamed R Mughal, Trent M Woodruff, Sic L Chan, Vardan T Karamyan, Mark P Mattson, Thiruma V Arumuga. Pivotal role for beta-1 integrin in neurovascular remodelling after ischemic stroke. Experimental neurology. vol 221. issue 1. 2010-02-16. PMID:19837065. |
at 24 h after cerebral ischemia and reperfusion (i/r), the ischemic cortex (ipsilateral area) exhibited modest beta1 integrin immunoreactivity and a robust increase was observed at 72 h. double-label immunohistochemical analysis for beta1 integrin with neuronal (neun), microglial (iba-1), astrocyte (gfap), progenitor cell (ng2) and blood vessel (collagen 4) markers showed that beta1 integrin expression only localized to blood vessels. |
2010-02-16 |
2023-08-12 |
Not clear |
| Elaine S Coleman, John C Dennis, Timothy D Braden, Robert L Judd, Phil Posne. Insulin treatment prevents diabetes-induced alterations in astrocyte glutamate uptake and GFAP content in rats at 4 and 8 weeks of diabetes duration. Brain research. vol 1306. 2010-02-03. PMID:19822133. |
insulin treatment prevents diabetes-induced alterations in astrocyte glutamate uptake and gfap content in rats at 4 and 8 weeks of diabetes duration. |
2010-02-03 |
2023-08-12 |
rat |
| Elaine S Coleman, John C Dennis, Timothy D Braden, Robert L Judd, Phil Posne. Insulin treatment prevents diabetes-induced alterations in astrocyte glutamate uptake and GFAP content in rats at 4 and 8 weeks of diabetes duration. Brain research. vol 1306. 2010-02-03. PMID:19822133. |
we report here a comparison of astrocyte glutamate uptake and gfap expression in streptozotocin-induced type 1 diabetic rats and insulin-treated diabetic rats at 4 and 8 weeks following diabetes onset. |
2010-02-03 |
2023-08-12 |
rat |
| Rômulo Sperduto Dezonne, Joice Stipursky, Flávia Carvalho Alcantara Gome. Effect of thyroid hormone depletion on cultured murine cerebral cortex astrocytes. Neuroscience letters. vol 467. issue 2. 2010-02-01. PMID:19818379. |
we investigated the effect of depletion of ths from fetal bovine serum (fbs) on the expression of the astrocyte maturation markers, gfap (glial fibrillary acidic protein) and s100beta, and the extracellular matrix (ecm) proteins laminin and fibronectin in cultured astrocytes. |
2010-02-01 |
2023-08-12 |
cattle |