| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Song Qin, Menglu Liu, Wenze Niu, Chun-Li Zhan. Dysregulation of Kruppel-like factor 4 during brain development leads to hydrocephalus in mice. Proceedings of the National Academy of Sciences of the United States of America. vol 108. issue 52. 2012-02-21. PMID:22160720. |
these characteristics were accompanied by elevation of gfap expression and astrocyte hypertrophy. |
2012-02-21 |
2023-08-12 |
mouse |
| Mohammad Amin Sherafat, Mohammad Javan, Sabah Mozafari, Javad Mirnajafi-Zadeh, Fereshteh Motamed. Castration attenuates myelin repair following lysolecithin induced demyelination in rat optic chiasm: an evaluation using visual evoked potential, marker genes expression and myelin staining. Neurochemical research. vol 36. issue 10. 2012-02-08. PMID:21626170. |
in this study, we investigate the effect of castration on lysolecithin-induced demyelination and remyelination processes using visual evoked potentials, in addition to measuring the expressions of olig2, mbp, nogo-a and gfap mrnas as oligodendrocyte or astrocyte markers; and histological assessments by myelin-specific staining. |
2012-02-08 |
2023-08-12 |
rat |
| Xiehuang Sheng, Nannan Zhang, Shuliang Song, Min Li, Hao Liang, Yuejie Zhang, Yunshan Wang, Aiguo J. Morphological transformation and proliferation of rat astrocytes as induced by sulfated polysaccharides from the sea cucumber Stichopus japonicus. Neuroscience letters. vol 503. issue 1. 2012-01-18. PMID:21855606. |
however, combinational treatment of hs and fgf-2 promoted transformation of normal astrocyte into a stella morphology (stellation), along with an increase in the expression and rearrangement of glial fibrillary acidic protein (gfap). |
2012-01-18 |
2023-08-12 |
rat |
| Irina Burd, Amy Brown, Juan M Gonzalez, Jinghua Chai, Michal A Elovit. A mouse model of term chorioamnionitis: unraveling causes of adverse neurological outcomes. Reproductive sciences (Thousand Oaks, Calif.). vol 18. issue 9. 2012-01-11. PMID:21421895. |
marker of astrocyte development and astrogliosis (glial fibrillary acidic protein [gfap]) did not show an increase; pro-oligodendrocyte marker (plp1/dm20) was not significantly changed (p > .05). |
2012-01-11 |
2023-08-12 |
mouse |
| Mithu Storoni, Axel Petzold, Gordon T Plan. The use of serum glial fibrillary acidic protein measurements in the diagnosis of neuromyelitis optica spectrum optic neuritis. PloS one. vol 6. issue 8. 2011-12-30. PMID:21876753. |
glial fibrillary acidic protein (gfap) is a specific intermediate filament of the cytoskeleton of the astrocyte and may be used as a specific marker for astrocytic damage. |
2011-12-30 |
2023-08-12 |
Not clear |
| Yue-Mao Zheng, Yong-Hui Dang, Yong-Ping Xu, Wu-Jia-Fu Sai, Zhi-Xing A. Differentiation of AFS cells derived from the EGFP gene transgenic porcine fetuses. Cell biology international. vol 35. issue 8. 2011-12-22. PMID:21073446. |
undifferentiated afss (amniotic fluid-derived stem cells) expressed pou5f1, thy1 and sox2, while the following differentiation cells expressed markers for chondrogenic (col2a1), osteogenic (osteocalcin and osteonectin) and neurogenic cells such as astrocyte (gfap), oligodendrocyte (galc) and neuron (nf, eno2 and map). |
2011-12-22 |
2023-08-12 |
Not clear |
| Yi-Song Chen, Suh-Ciuan Lim, Mei-Hsuan Chen, Roy A Quinlan, Ming-Der Pern. Alexander disease causing mutations in the C-terminal domain of GFAP are deleterious both to assembly and network formation with the potential to both activate caspase 3 and decrease cell viability. Experimental cell research. vol 317. issue 16. 2011-12-22. PMID:21756903. |
alexander disease is a primary genetic disorder of astrocyte caused by dominant mutations in the astrocyte-specific intermediate filament glial fibrillary acidic protein (gfap). |
2011-12-22 |
2023-08-12 |
Not clear |
| Julie E Simpson, Paul G Ince, Pamela J Shaw, Paul R Heath, Rohini Raman, Claire J Garwood, Catherine Gelsthorpe, Lynne Baxter, Gillian Forster, Fiona E Matthews, Carol Brayne, Stephen B Wharto. Microarray analysis of the astrocyte transcriptome in the aging brain: relationship to Alzheimer's pathology and APOE genotype. Neurobiology of aging. vol 32. issue 10. 2011-12-15. PMID:21705112. |
to understand the role of astrocytes in the pathogenesis of age-related disorders, we isolated astrocytes by laser capture microdissection, using glial fibrillary acidic protein (gfap) as a marker, and characterized the astrocyte transcriptome at different braak neurofibrillary tangle stages in postmortem temporal cortex samples derived from the medical research council cognitive function and ageing study (mrc cfas) cohort, using microarray analysis. |
2011-12-15 |
2023-08-12 |
Not clear |
| Huai-Cai Zeng, Ling Zhang, Yuan-Yuan Li, Yan-Jian Wang, Wei Xia, Yi Lin, Jie Wei, Shun-Qing X. Inflammation-like glial response in rat brain induced by prenatal PFOS exposure. Neurotoxicology. vol 32. issue 1. 2011-12-09. PMID:20937303. |
astrocyte activation markers, glial fibrillary acidic protein (gfap) and s100 calcium binding protein b (s-100β) in hippocampus and cortex were both upregulated on postnatal day 0 (pnd0) or pnd21. |
2011-12-09 |
2023-08-12 |
rat |
| Minfeng Shu, Yuxi Zhou, Wenbo Zhu, Sihan Wu, Xiaoke Zheng, Guangmei Ya. Activation of a pro-survival pathway IL-6/JAK2/STAT3 contributes to glial fibrillary acidic protein induction during the cholera toxin-induced differentiation of C6 malignant glioma cells. Molecular oncology. vol 5. issue 3. 2011-12-09. PMID:21470923. |
glial fibrillary acidic protein (gfap) is a well-known specific astrocyte biomarker and acts as a tumor suppressor gene (tsg) in glioma pathogenesis. |
2011-12-09 |
2023-08-12 |
rat |
| Ellora Sen, Anirban Basu, Lisa B Willing, Tracy F Uliasz, Jaimie L Myrkalo, Susan J Vannucci, Sandra J Hewett, Steven W Leviso. Pre-conditioning induces the precocious differentiation of neonatal astrocytes to enhance their neuroprotective properties. ASN neuro. vol 3. issue 3. 2011-11-14. PMID:21722095. |
hypoxia increased neocortical astrocyte maturation as evidenced by the loss of gfap (glial fibrillary acidic protein)-positive cells with radial morphologies and the acquisition of multipolar gfap-positive cells. |
2011-11-14 |
2023-08-12 |
rat |
| Luca Caracciolo, Alessandro Barbon, Sara Palumbo, Cristina Mora, Christopher D Toscano, Francesca Bosetti, Sergio Barlat. Altered mRNA editing and expression of ionotropic glutamate receptors after kainic acid exposure in cyclooxygenase-2 deficient mice. PloS one. vol 6. issue 5. 2011-09-21. PMID:21589914. |
after ka exposure, cox-2(-/-) mice showed increased mrna expression of markers of inflammation and oxidative stress, such as cytokines (tnf-α, il-1β and il-6), inducible nitric oxide synthase (inos), microglia (cd11b) and astrocyte (gfap). |
2011-09-21 |
2023-08-12 |
mouse |
| Subbiah Pugazhenthi, Sreekala Nair, Kalpana Velmurugan, Qiaoling Liang, Ravi Mahalingam, Randall J Cohrs, Maria A Nagel, Don Gilde. Varicella-zoster virus infection of differentiated human neural stem cells. Journal of virology. vol 85. issue 13. 2011-08-25. PMID:21525352. |
immunostaining with neuronal (map2a and β-tubulin), astrocyte (gfap), and oligodendrocyte (cnpase) markers revealed that differentiated neurons constituted approximately 90% of the cell population. |
2011-08-25 |
2023-08-12 |
mouse |
| Miriam S Domowicz, Judith G Henry, Natasha Wadlington, Antonia Navarro, Richard P Kraig, Nancy B Schwart. Astrocyte precursor response to embryonic brain injury. Brain research. vol 1389. 2011-08-23. PMID:21396923. |
in contrast, the mature astrocyte marker, gfap, was up-regulated at the wound site, around necrotic areas and cysts, plus in usual areas of gfap expression. |
2011-08-23 |
2023-08-12 |
human |
| Thomas E Nelson, Christine Hao, Jessica Manos, R M Ransohoff, Donna L Gruo. Altered hippocampal synaptic transmission in transgenic mice with astrocyte-targeted enhanced CCL2 expression. Brain, behavior, and immunity. vol 25 Suppl 1. 2011-08-08. PMID:21356306. |
western blot analysis of hippocampus from the ccl2 transgenic mice and non-transgenic mice showed no change in level of neuronal specific enolase, a neuronal specific protein, gfap, an astrocyte specific protein, and several synaptic proteins compared with non-transgenic littermate controls. |
2011-08-08 |
2023-08-12 |
mouse |
| S Jinn. Regional and laminar differences in antigen profiles and spatial distributions of astrocytes in the mouse hippocampus, with reference to aging. Neuroscience. vol 180. 2011-08-04. PMID:21320577. |
here we used two established astrocyte markers, that is, glial fibrillary acidic protein (gfap) and s100β, to identify the astrocyte population. |
2011-08-04 |
2023-08-12 |
mouse |
| Jun Yokose, Toru Ishizuka, Takeshi Yoshida, Jun Aoki, Yoshio Koyanagi, Hiromu Yaw. Lineage analysis of newly generated neurons in organotypic culture of rat hippocampus. Neuroscience research. vol 69. issue 3. 2011-07-29. PMID:21145363. |
at 28 days post-inoculation, the phenotypes of the cells were immunohistochemically identified using specific antibodies to cell-type markers such as huc/d (pan-neuronal marker), gfap (astrocyte marker), prox1 (dentate granule cell marker) or neun (mature neuronal marker). |
2011-07-29 |
2023-08-12 |
rat |
| Krithi Irmady, Sabrina Zechel, Klaus Unsicke. Fibroblast growth factor 2 regulates astrocyte differentiation in a region-specific manner in the hindbrain. Glia. vol 59. issue 5. 2011-07-25. PMID:21322057. |
the methylation of histone h3 at lysine 4 residue (h3k4me2) associated with the stat (signal transducer and activator of transcription)-binding site of the gfap promoter was significantly decreased in the gray matter of the fgf-2 null mouse, suggesting a role for fgf-2 in the epigenetic regulation of astrocyte differentiation in vivo. |
2011-07-25 |
2023-08-12 |
mouse |
| Cristina García-Cáceres, Esther Fuente-Martín, Emma Burgos-Ramos, Miriam Granado, Laura M Frago, Vicente Barrios, Tamas Horvath, Jesús Argente, Julie A Chowe. Differential acute and chronic effects of leptin on hypothalamic astrocyte morphology and synaptic protein levels. Endocrinology. vol 152. issue 5. 2011-07-22. PMID:21343257. |
here we report that astrocyte structural proteins, such as glial fibrillary acidic protein (gfap) and vimentin, are induced and astrocyte morphology modified by chronic leptin administration (intracerebroventricular, 2 wk), with these changes being inversely related to modifications in synaptic protein densities. |
2011-07-22 |
2023-08-12 |
rat |
| Cristina García-Cáceres, Esther Fuente-Martín, Emma Burgos-Ramos, Miriam Granado, Laura M Frago, Vicente Barrios, Tamas Horvath, Jesús Argente, Julie A Chowe. Differential acute and chronic effects of leptin on hypothalamic astrocyte morphology and synaptic protein levels. Endocrinology. vol 152. issue 5. 2011-07-22. PMID:21343257. |
in primary hypothalamic astrocyte cultures leptin also reduced gfap levels at 1 h, with an induction at 24 h, indicating a possible direct effect of leptin. |
2011-07-22 |
2023-08-12 |
rat |