| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Shan-Xue Jin, Zhi-Ye Zhuang, Clifford J Woolf, Ru-Rong J. p38 mitogen-activated protein kinase is activated after a spinal nerve ligation in spinal cord microglia and dorsal root ganglion neurons and contributes to the generation of neuropathic pain. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 10. 2003-06-25. PMID:12764087. |
the activated p38 in the spinal cord is restricted entirely to microglia; phospho-p38 colocalizes only with the microglial marker ox-42 and not with either the neuronal marker neuronal-specific nuclear protein or the astrocyte marker gfap. |
2003-06-25 |
2023-08-12 |
rat |
| Norbert Braun, Jean Sévigny, Santosh K Mishra, Simon C Robson, Stephan W Barth, Ruediger Gerstberger, Klaus Hammer, Herbert Zimmerman. Expression of the ecto-ATPase NTPDase2 in the germinal zones of the developing and adult rat brain. The European journal of neuroscience. vol 17. issue 7. 2003-06-20. PMID:12713638. |
double labelling for the astrocyte intermediate filament protein gfap and the glial glutamate transporter glast identifies the ntpdase2-positive cells as type-b cells. |
2003-06-20 |
2023-08-12 |
rat |
| Norbert Braun, Jean Sévigny, Santosh K Mishra, Simon C Robson, Stephan W Barth, Ruediger Gerstberger, Klaus Hammer, Herbert Zimmerman. Expression of the ecto-ATPase NTPDase2 in the germinal zones of the developing and adult rat brain. The European journal of neuroscience. vol 17. issue 7. 2003-06-20. PMID:12713638. |
during development the enzyme protein is first detected at e18, long before expression of the astrocyte marker gfap. |
2003-06-20 |
2023-08-12 |
rat |
| Q L Huan. [Studies on the effects of astrocyte during glial scar formation by recombinant antisense GFAP retrovirus]. Sheng li ke xue jin zhan [Progress in physiology]. vol 30. issue 2. 2003-06-17. PMID:12532806. |
[studies on the effects of astrocyte during glial scar formation by recombinant antisense gfap retrovirus]. |
2003-06-17 |
2023-08-12 |
Not clear |
| Q L Huan. [Studies on the effects of astrocyte during glial scar formation by recombinant antisense GFAP retrovirus]. Sheng li ke xue jin zhan [Progress in physiology]. vol 30. issue 2. 2003-06-17. PMID:12532806. |
the present study was to investigate the changes of macroglia and the effect of gonadal hormone on reactive gliosis and of antisense gfap retrovirus on astrocyte, gliosis and glial scar formation after brain stab injury (bsi). |
2003-06-17 |
2023-08-12 |
Not clear |
| Q L Huan. [Studies on the effects of astrocyte during glial scar formation by recombinant antisense GFAP retrovirus]. Sheng li ke xue jin zhan [Progress in physiology]. vol 30. issue 2. 2003-06-17. PMID:12532806. |
the recombined gfap retrovirus can effectively inhibit the growth of astrocyte, and gfap expression of injured astrocyte in vitro and glial scar forming in vivo. |
2003-06-17 |
2023-08-12 |
Not clear |
| Peter H Ashjian, Amir S Elbarbary, Brian Edmonds, Daniel DeUgarte, Min Zhu, Patricia A Zuk, H Peter Lorenz, Prosper Benhaim, Marc H Hedric. In vitro differentiation of human processed lipoaspirate cells into early neural progenitors. Plastic and reconstructive surgery. vol 111. issue 6. 2003-05-22. PMID:12711954. |
however, induced pla cells did not express the mature neuronal marker, map, or the mature astrocyte marker, gfap. |
2003-05-22 |
2023-08-12 |
human |
| Scott D Rogers, Christopher M Peters, James D Pomonis, Hiromi Hagiwara, Joseph R Ghilardi, Patrick W Manty. Endothelin B receptors are expressed by astrocytes and regulate astrocyte hypertrophy in the normal and injured CNS. Glia. vol 41. issue 2. 2003-04-02. PMID:12509808. |
optic nerve crush induces a marked increase in et(b)r and gfap immunoreactivity (ir) without inducing a significant increase in the number of gfap-ir astrocytes, suggesting that the crush-induced astrogliosis is due primarily to astrocyte hypertrophy. |
2003-04-02 |
2023-08-12 |
rabbit |
| Tânia Cristina Leite de Sampaio e Spohr, Rodrigo Martinez, Elen Federowicz da Silva, Vivaldo Moura Neto, Flávia Carvalho Alcantara Gome. Neuro-glia interaction effects on GFAP gene: a novel role for transforming growth factor-beta1. The European journal of neuroscience. vol 16. issue 11. 2003-03-25. PMID:12473073. |
by using a transgenic mouse bearing part of the gene promoter of the astrocytic maturation marker gfap (glial fibrillary acidic protein) linked to the beta-galactosidase (beta-gal) reporter gene, we previously demonstrated that cerebral cortical neurons increase transgenic beta-gal astrocyte number and activate gfap gene promoter by secretion of soluble factors in vitro. |
2003-03-25 |
2023-08-12 |
mouse |
| Giyasettin Baydas, Russel J Reiter, Viktor S Nedzvetskii, Peter A Nerush, Svetlana V Kirichenk. Altered glial fibrillary acidic protein content and its degradation in the hippocampus, cortex and cerebellum of rats exposed to constant light: reversal by melatonin. Journal of pineal research. vol 33. issue 3. 2003-03-17. PMID:12220326. |
one of the important events during astrocyte differentiation is the increased expression of glial fibrillary acidic protein (gfap), a member of the family of intermediate filament structural proteins. |
2003-03-17 |
2023-08-12 |
rat |
| Roberto Avola, Gianfrancesco Cormaci, Venera Mazzone, Luca Denaro, Fiorenzo Mignini, Daniele Tomassoni, Damiano Zacche. Effect of growth factors on DNA labeling and cytoskeletal protein expression in 17-beta-estradiol and basic fibroblast growth factor pre-treated astrocyte cultures. Clinical and experimental hypertension (New York, N.Y. : 1993). vol 24. issue 7-8. 2003-03-12. PMID:12450249. |
this study has investigated the interactions between growth factors and estrogens on dna labeling and cytoskeletal protein [glial fibrillary acidic protein (gfap) and vimentin] expression in 22 div astrocyte cultures treated for 24 or 36 h under different experimental conditions. |
2003-03-12 |
2023-08-12 |
Not clear |
| Atsumi Uemura, Takumi Takizawa, Wataru Ochiai, Makoto Yanagisawa, Kinichi Nakashima, Tetsuya Tag. Cardiotrophin-like cytokine induces astrocyte differentiation of fetal neuroepithelial cells via activation of STAT3. Cytokine. vol 18. issue 1. 2003-02-21. PMID:12090754. |
clc-stimulation led to promoter activation of the gene for an astrocyte marker, glial fibrillary acidic protein (gfap), which was clearly inhibited by expression of a dominant negative form of a transcription factor, stat3, or by introduction of a mutation in a single stat3-binding site in the promoter, suggesting a critical role of stat3 in the clc-induced gfap transcription. |
2003-02-21 |
2023-08-12 |
mouse |
| Melinda E Wilson, Ying Liu, Phyllis M Wis. Estradiol enhances Akt activation in cortical explant cultures following neuronal injury. Brain research. Molecular brain research. vol 102. issue 1-2. 2003-02-11. PMID:12191493. |
other sections were used for immunohistochemistry to determine whether cells that stained positive for activated caspase 3 were also immunopositive for neun, a neuronal marker, or gfap, an astrocyte marker. |
2003-02-11 |
2023-08-12 |
rat |
| E-M Fröjdö, J Westerlund, B Isoma. Culturing and characterization of astrocytes isolated from juvenile rainbow trout (Oncorhynchus mykiss). Comparative biochemistry and physiology. Part A, Molecular & integrative physiology. vol 133. issue 1. 2003-02-07. PMID:12160869. |
on such a culture substrate and with a seeding density of 1 x 10(7) cells/cm(2) confluence was obtained within 3-4 weeks at an incubation temperature of 18 degrees c. approximately 95% of the cells were identified as astrocytes on the basis of a positive staining with antibodies against the astrocyte specific glial protein (gfap). |
2003-02-07 |
2023-08-12 |
Not clear |
| Jianping Wang, Robert D Schreiber, Iain L Campbel. STAT1 deficiency unexpectedly and markedly exacerbates the pathophysiological actions of IFN-alpha in the central nervous system. Proceedings of the National Academy of Sciences of the United States of America. vol 99. issue 25. 2003-01-28. PMID:12461178. |
to establish the role of stat1 in mediating the biological actions of ifn-alpha in the cns, transgenic mice [termed glial fibrillary acidic protein (gfap)-ifn-alpha] with astrocyte production of ifn-alpha were bred to be null for the stat1 gene. |
2003-01-28 |
2023-08-12 |
mouse |
| Tirupapuliyar V Damodaran, Magdalena A Bilska, Ali A Rahman, Mohamed B Abou-Don. Sarin causes early differential alteration and persistent overexpression in mRNAs coding for glial fibrillary acidic protein (GFAP) and vimentin genes in the central nervous system of rats. Neurochemical research. vol 27. issue 5. 2002-12-04. PMID:12064357. |
overall it is also clear that both gfap and vimentin are needed for the effective recovery involving co-ordinated alternating up- and downregulation of these two key astrocyte genes, depending on tissue specificity. |
2002-12-04 |
2023-08-12 |
rat |
| Tirupapuliyar V Damodaran, Magdalena A Bilska, Ali A Rahman, Mohamed B Abou-Don. Sarin causes early differential alteration and persistent overexpression in mRNAs coding for glial fibrillary acidic protein (GFAP) and vimentin genes in the central nervous system of rats. Neurochemical research. vol 27. issue 5. 2002-12-04. PMID:12064357. |
the changes seen in the transcript levels of gfap and vimentin may be the result of astrocyte dysfunction and loss, accompanied by compensatory proliferation and dedifferentiation of the astroglia. |
2002-12-04 |
2023-08-12 |
rat |
| Trícia Kommers, Richard Rodnight, Carina Boeck, Deusa Vendite, Diogo Oliveira, Joel Horn, Daniela Oppelt, Susana Wofchu. Phosphorylation of glial fibrillary acidic protein is stimulated by glutamate via NMDA receptors in cortical microslices and in mixed neuronal/glial cell cultures prepared from the cerebellum. Brain research. Developmental brain research. vol 137. issue 2. 2002-11-26. PMID:12220706. |
in previous work we showed that phosphorylation of glial fibrillary acidic protein (gfap), an astrocyte marker, is increased by glutamate in hippocampal slices from immature rats via a type ii metabotropic receptor. |
2002-11-26 |
2023-08-12 |
rat |
| M A Moscarello, B Mak, T A Nguyen, D D Wood, F Mastronardi, S K Ludwi. Paclitaxel (Taxol) attenuates clinical disease in a spontaneously demyelinating transgenic mouse and induces remyelination. Multiple sclerosis (Houndmills, Basingstoke, England). vol 8. issue 2. 2002-11-18. PMID:11990870. |
if given at 2 months of age (1 month prior to clinical signs), disease was almost completely prevented the astrogliosis, prominent in our model, was reversed by paditaxel as determined by astrocyte counts and quantitation of gfap. |
2002-11-18 |
2023-08-12 |
mouse |
| Weihong Ge, Keri Martinowich, Xiangbing Wu, Fei He, Alison Miyamoto, Guoping Fan, Gerry Weinmaster, Yi Eve Su. Notch signaling promotes astrogliogenesis via direct CSL-mediated glial gene activation. Journal of neuroscience research. vol 69. issue 6. 2002-10-24. PMID:12205678. |
we report here that the astrogliogenic role of notch is in part mediated by direct binding of the notch intracellular domain to the csl dna binding protein, forming a transcriptional activation complex onto the astrocyte marker gene, glial fibrillary acidic protein (gfap). |
2002-10-24 |
2023-08-12 |
Not clear |