Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Masaaki Takemura, Hiroshi Gomi, Emma Colucci-Guyon, Shigeyoshi Itohar. Protective role of phosphorylation in turnover of glial fibrillary acidic protein in mice. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 16. 2002-09-04. PMID:12177195. |
glial fibrillary acidic protein (gfap), the principal intermediate filament (if) protein of mature astrocytes in the cns, plays specific roles in astrocyte functions. |
2002-09-04 |
2023-08-12 |
mouse |
Michaela Livia Bajenaru, Yuan Zhu, Nicolé M Hedrick, Jessica Donahoe, Luis F Parada, David H Gutman. Astrocyte-specific inactivation of the neurofibromatosis 1 gene (NF1) is insufficient for astrocytoma formation. Molecular and cellular biology. vol 22. issue 14. 2002-07-19. PMID:12077339. |
in an effort to determine the contribution of the nf1 gene product, neurofibromin, to astrocyte growth regulation and nf1-associated astrocytoma formation, we generated astrocyte-specific nf1 conditional knockout mice (nf1(gfap)cko) by using cre/loxp technology. |
2002-07-19 |
2023-08-12 |
mouse |
C Guerri, M Pascual, J Renau-Piquera. Glia and fetal alcohol syndrome. Neurotoxicology. vol 22. issue 5. 2002-05-22. PMID:11770880. |
in astrocytes in primary culture, ethanol has been found to (1) impair cell growth and differentiation, (2) decrease the levels of glialfibrillary acidic protein or gfap (an astrocyte marker) and its gene expression and (3) interfere with the stimulatory effect of trophic factors affecting their release and receptor expression. |
2002-05-22 |
2023-08-12 |
Not clear |
S A Headley, I C Soares, D L Graç. Glial fibrillary acidic protein (GFAP)-immunoreactive astrocytes in dogs infected with canine distemper virus. Journal of comparative pathology. vol 125. issue 2-3. 2002-05-09. PMID:11578123. |
an experiment based on astrocyte immunoreactivity to glial fibrillary acidic protein (gfap) was designed to determine whether the astrocyte response in canine distemper encephalitis (cde) was associated with the age of the animal, type of lesion and the cerebellar region affected. |
2002-05-09 |
2023-08-12 |
Not clear |
Attila D Kovács, Gvido Cebers, Aleta Cebere, Sture Liljequis. Selective and AMPA receptor-dependent astrocyte death following prolonged blockade of glutamate reuptake in rat cerebellar cultures. Experimental neurology. vol 174. issue 1. 2002-03-28. PMID:11869034. |
immunofluorescence staining for the glial-specific intermediate filament protein, gfap, revealed that the pdc- induced increase of extracellular glutamate concentration was accompanied by increased astrocyte death, while neurons and oligodendrocytes remained intact and viable. |
2002-03-28 |
2023-08-12 |
rat |
Jenafer Evans, Colin Sumners, Jennifer Moore, Matthew J Huentelman, Jie Deng, Craig H Gelband, Gerry Sha. Characterization of mitotic neurons derived from adult rat hypothalamus and brain stem. Journal of neurophysiology. vol 87. issue 2. 2002-03-26. PMID:11826071. |
at day 7 in tissue culture and beyond, the predominant cell types in hypothalamic and brain stem cultures had a stellate morphology and could be subdivided into two distinct groups, one of which stained with antibodies to the immature neuron marker alpha-internexin, while the other stained with the astrocyte marker gfap. |
2002-03-26 |
2023-08-12 |
rat |
Assia Catalani, Maurizio Sabbatini, Claudia Consoli, Carlo Cinque, Daniele Tomassoni, Efrain Azmitia, Luciano Angelucci, Francesco Ament. Glial fibrillary acidic protein immunoreactive astrocytes in developing rat hippocampus. Mechanisms of ageing and development. vol 123. issue 5. 2002-03-19. PMID:11796133. |
the volume of different portions of hippocampus, the number and the size of astrocytes, the intensity of cell body gfap immunostaining as well as the extension of astrocyte were assessed. |
2002-03-19 |
2023-08-12 |
rat |
Per M Almqvist, Richard Mah, Urban Lendahl, Björn Jacobsson, Glenda Hendso. Immunohistochemical detection of nestin in pediatric brain tumors. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society. vol 50. issue 2. 2002-03-19. PMID:11799134. |
in all tumors nestin immunoreactivity was confined to the cytoplasm of tumor cells and was co-expressed with astrocyte markers vimentin, gfap, and s-100. |
2002-03-19 |
2023-08-12 |
Not clear |
L Guo, A Sawkar, M Zasadzki, D M Watterson, L J Van Eldi. Similar activation of glial cultures from different rat brain regions by neuroinflammatory stimuli and downregulation of the activation by a new class of small molecule ligands. Neurobiology of aging. vol 22. issue 6. 2002-02-28. PMID:11755006. |
the end points assayed included il-1beta, inos, apoe and the astrocyte marker protein gfap. |
2002-02-28 |
2023-08-12 |
rat |
Eric A Bushong, Maryann E Martone, Ying Z Jones, Mark H Ellisma. Protoplasmic astrocytes in CA1 stratum radiatum occupy separate anatomical domains. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 1. 2002-02-04. PMID:11756501. |
our current understanding of astrocyte form and distribution is based predominantly on studies that used the astrocytic marker glial fibrillary acidic protein (gfap) and on studies using metal-impregnation techniques. |
2002-02-04 |
2023-08-12 |
Not clear |
Eric A Bushong, Maryann E Martone, Ying Z Jones, Mark H Ellisma. Protoplasmic astrocytes in CA1 stratum radiatum occupy separate anatomical domains. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 1. 2002-02-04. PMID:11756501. |
in the present study, intracellular injection combined with immunohistochemistry for gfap show that gfap delineates only approximately 15% of the total volume of the astrocyte. |
2002-02-04 |
2023-08-12 |
Not clear |
S Araneda, N Mermet, T Verjat, J F Angulo, J P Radicell. Expression of Kin17 and 8-OxoG DNA glycosylase in cells of rodent and quail central nervous system. Brain research bulletin. vol 56. issue 2. 2002-01-04. PMID:11704351. |
to characterize the expression of these proteins in cell types of rodent and avian brains, we combined immunocytochemistry for either kin17 or ogg1 proteins with glial fibrillary acidic protein (gfap, an astrocyte marker) immunodetection on the same tissue section. |
2002-01-04 |
2023-08-12 |
mouse |
C Röhl, M Gülden, H Seiber. Toxicity of organotin compounds in primary cultures of rat cortical astrocytes. Cell biology and toxicology. vol 17. issue 1. 2001-12-12. PMID:11504447. |
the aim of this study was to investigate whether trialkyltin derivatives can induce an increased gfap synthesis in astrocyte cultures in the absence of neurons and whether differences between the action of tmt, tet, and tbt can be detected. |
2001-12-12 |
2023-08-12 |
rat |
b' M Anderov\\xc3\\xa1, S Kubinov\\xc3\\xa1, T Mazel, A Chv\\xc3\\xa1tal, C Eliasson, M Pekny, E Sykov\\xc3\\xa. Effect of elevated K(+), hypotonic stress, and cortical spreading depression on astrocyte swelling in GFAP-deficient mice. Glia. vol 35. issue 3. 2001-10-04. PMID:11494410.' |
to assess its function in astrocyte swelling, we compared astrocyte membrane properties and swelling in spinal cord slices of 8- to 10-day-old wild-type control (gfap(+/+)) and gfap-knockout (gfap(-/-)) mice. |
2001-10-04 |
2023-08-12 |
mouse |
b' M Anderov\\xc3\\xa1, S Kubinov\\xc3\\xa1, T Mazel, A Chv\\xc3\\xa1tal, C Eliasson, M Pekny, E Sykov\\xc3\\xa. Effect of elevated K(+), hypotonic stress, and cortical spreading depression on astrocyte swelling in GFAP-deficient mice. Glia. vol 35. issue 3. 2001-10-04. PMID:11494410.' |
astrocyte swelling evoked by application of 50 mm k(+) or by hypotonic solution (hs) produced a larger increase in [k(+)](e) around gfap(+/+) astrocytes than around gfap(-/-) astrocytes. |
2001-10-04 |
2023-08-12 |
mouse |
L Struzyñska, I Bubko, M Walski, U Rafałowsk. Astroglial reaction during the early phase of acute lead toxicity in the adult rat brain. Toxicology. vol 165. issue 2-3. 2001-10-04. PMID:11522370. |
the results of current studies indicate that acute lead exposure is accompanied by astrocyte activation connected with the presence of the enhanced expression of gfap. |
2001-10-04 |
2023-08-12 |
rat |
W Ochiai, M Yanagisawa, T Takizawa, K Nakashima, T Tag. Astrocyte differentiation of fetal neuroepithelial cells involving cardiotrophin-1-induced activation of STAT3. Cytokine. vol 14. issue 5. 2001-09-27. PMID:11444906. |
ct-1-stimulation led to promoter activation of the gene for an astrocyte marker, glial fibrillary acidic protein (gfap), which was clearly inhibited by expression of a dominant negative form of a gp130-downstream transcription factor, signal transducer and activator of transcription 3(stat3), or by introduction of a mutation in a single stat3-binding site in the promoter, suggesting a critical role of stat3 in the ct-1-induced gfap transcription. |
2001-09-27 |
2023-08-12 |
mouse |
S Cantagrel, P Gressens, S Bodard, A L Suc, J Laugier, D Guilloteau, S Chalo. mRNA D(2) dopaminergic receptor expression after hypoxia-ischemia in rat immature brain. Biology of the neonate. vol 80. issue 1. 2001-09-27. PMID:11474153. |
there were no differences in total cell number and in the expression of neuronal (map-1, map-2) and astrocyte (gfap) markers between both brain hemispheres nor between control and hypoxia-ischemia animals. |
2001-09-27 |
2023-08-12 |
rat |
J J Yan, J Y Cho, H S Kim, K L Kim, J S Jung, S O Huh, H W Suh, Y H Kim, D K Son. Protection against beta-amyloid peptide toxicity in vivo with long-term administration of ferulic acid. British journal of pharmacology. vol 133. issue 1. 2001-07-26. PMID:11325798. |
in addition, a beta 1-42 increased immunoreactivities of the astrocyte marker glial fibrillary acidic protein (gfap) and interleukin-1 beta (il-1 beta) in the hippocampus, effects also suppressed by pretreatment with ferulic acid. |
2001-07-26 |
2023-08-12 |
mouse |
K Kopatz, C Distle. Astrocyte invasion and vasculogenesis in the developing ferret retina. Journal of neurocytology. vol 29. issue 3. 2001-07-26. PMID:11428047. |
we studied the time course of astrocyte invasion and blood vessel formation in the developing ferret retina using glial fibrillary acidic protein (gfap)-immunohistochemistry for astrocytes and isolectin b4 histochemistry for blood vessels. |
2001-07-26 |
2023-08-12 |
Not clear |