| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Demeule, M Labelle, A Régina, F Berthelet, R Bélivea. Isolation of endothelial cells from brain, lung, and kidney: expression of the multidrug resistance P-glycoprotein isoforms. Biochemical and biophysical research communications. vol 281. issue 3. 2001-04-19. PMID:11237734. |
the multidrug resistance p-glycoprotein (p-gp) was strongly enriched (59-fold) in the ec fraction from brain and was absent in the negative fraction, in which the glial fibrillary acidic protein (gfap), an astrocyte marker, was present. |
2001-04-19 |
2023-08-12 |
Not clear |
| M Yanagisawa, K Nakashima, T Takizawa, W Ochiai, H Arakawa, T Tag. Signaling crosstalk underlying synergistic induction of astrocyte differentiation by BMPs and IL-6 family of cytokines. FEBS letters. vol 489. issue 2-3. 2001-03-15. PMID:11165238. |
we here show that bone morphogenetic protein (bmp) 7 acted in synergy with the distinct type of cytokines, leukemia inhibitory factor (lif) and interleukin (il) 6 that are in the il-6 family, to induce astrocyte differentiation from neuroepithelial cells as assessed by expression of glial fibrillary acidic protein (gfap). |
2001-03-15 |
2023-08-12 |
Not clear |
| L F Eng, R S Ghirnikar, Y L Le. Glial fibrillary acidic protein: GFAP-thirty-one years (1969-2000). Neurochemical research. vol 25. issue 9-10. 2001-02-15. PMID:11059815. |
as a member of the cytoskeletal protein family, gfap is thought to be important in modulating astrocyte motility and shape by providing structural stability to astrocytic processes. |
2001-02-15 |
2023-08-12 |
mouse |
| L F Eng, R S Ghirnikar, Y L Le. Glial fibrillary acidic protein: GFAP-thirty-one years (1969-2000). Neurochemical research. vol 25. issue 9-10. 2001-02-15. PMID:11059815. |
in addition to the major application of gfap antisera for routine use in astrocyte identification in the cns, the molecular cloning of the mouse gene in 1985 has opened a new and rich realm for gfap studies. |
2001-02-15 |
2023-08-12 |
mouse |
| S Medrano, O Stewar. Differential mRNA localization in astroglial cells in culture. The Journal of comparative neurology. vol 430. issue 1. 2001-02-08. PMID:11135245. |
the results indicate that cultured type-2 astrocytes have the capacity to sort mrnas to different subcellular domains and that the localization of gfap mrna to astrocyte processes requires intact microtubules. |
2001-02-08 |
2023-08-12 |
Not clear |
| T Gotohda, I Tokunaga, S Kubo, K Morita, O Kitamura, A Eguch. Effect of toluene inhalation on astrocytes and neurotrophic factor in rat brain. Forensic science international. vol 113. issue 1-3. 2000-11-16. PMID:10978631. |
thus, the elevation of gfap expression was induced by astrocyte activation rather than by cell proliferation. |
2000-11-16 |
2023-08-12 |
rat |
| D Mangoura, C Pelletiere, S Leung, N Sakellaridis, D X Wan. Prolactin concurrently activates src-PLD and JAK/Stat signaling pathways to induce proliferation while promoting differentiation in embryonic astrocytes. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 18. issue 7. 2000-10-19. PMID:10978848. |
a rapid translocation of the cytosolic stats over the nucleus was seen in nearly every astrocyte corresponding well with the gains in gfap per cell. |
2000-10-19 |
2023-08-12 |
Not clear |
| V Menet, M Giménez Y Ribotta, F Sandillon, A Priva. GFAP null astrocytes are a favorable substrate for neuronal survival and neurite growth. Glia. vol 31. issue 3. 2000-10-16. PMID:10941153. |
this may be correlated with the relatively late occurrence of gfap expression in astrocyte maturation when the early steps of neurogenesis are completed. |
2000-10-16 |
2023-08-12 |
mouse |
| R F Iacono, M I Berrí. A quantitative approach to correlate astrocyte differentiation and phagocytic activity. Biocell : official journal of the Sociedades Latinoamericanas de Microscopia Electronica ... et. al. vol 24. issue 2. 2000-10-04. PMID:10979613. |
a triple staining procedure (pap labeling for gfap, pas reaction for added yeast cells and hematoxylin for nuclear staining of the whole cell monolayer) had disclosed that junin virus infection enhanced phagocytic activity by inducing greater astrocyte differentiation. |
2000-10-04 |
2023-08-12 |
Not clear |
| F Labombarda, S Gonzalez, P Roig, A Lima, R Guennoun, M Schumacher, A F De Nicol. Modulation of NADPH-diaphorase and glial fibrillary acidic protein by progesterone in astrocytes from normal and injured rat spinal cord. The Journal of steroid biochemistry and molecular biology. vol 73. issue 3-4. 2000-09-25. PMID:10925216. |
to study its potential effects in the spinal cord, we investigated p4 modulation (4 mg/kg/day for 3 days) of two proteins responding to injury: nadph-diaphorase, an enzyme with nitric oxide synthase activity, and glial fibrillary acidic protein (gfap), a marker of astrocyte reactivity. |
2000-09-25 |
2023-08-12 |
rat |
| H Nawashiro, M Brenner, S Fukui, K Shima, J M Hallenbec. High susceptibility to cerebral ischemia in GFAP-null mice. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 20. issue 7. 2000-08-03. PMID:10908037. |
the authors tested this hypothesis by using a mouse ischemia model to compare the infarct volume produced in wild-type mice with that produced in mice lacking glial fibrillary acidic protein (gfap), an astrocyte specific intermediate filament component. |
2000-08-03 |
2023-08-12 |
mouse |
| M Monzón-Mayor, M Alvarez, J Arbelo-Galván, M Romero-Alemán, C Yanes, M L Plaza, J R Rodríguez, J J Rodríguez, A Toledan. Long-term evolution of local, proximal and remote astrocyte responses after diverse nucleus basalis lesioning (an experimental Alzheimer model): GFAP immunocytochemical study. Brain research. vol 865. issue 2. 2000-07-24. PMID:10821927. |
long-term evolution of local, proximal and remote astrocyte responses after diverse nucleus basalis lesioning (an experimental alzheimer model): gfap immunocytochemical study. |
2000-07-24 |
2023-08-12 |
rat |
| J B Grinspan, E Edell, D F Carpio, J S Beesley, L Lavy, D Pleasure, J A Golde. Stage-specific effects of bone morphogenetic proteins on the oligodendrocyte lineage. Journal of neurobiology. vol 43. issue 1. 2000-05-23. PMID:10756062. |
oligodendrocyte preprogenitors (psa-ncam+, a2b5-) treated with bmp2 or bmp4 developed a novel astrocyte phenotype characterized by a morphological change and expression of glial fibrillary acidic protein (gfap) but little glutamine synthetase expression and no labeling with a2b5 antibody. |
2000-05-23 |
2023-08-12 |
Not clear |
| M J Carlucci, L A Scolaro, E B Damont. Inhibitory action of natural carrageenans on Herpes simplex virus infection of mouse astrocytes. Chemotherapy. vol 45. issue 6. 2000-05-04. PMID:10567773. |
the increase in the expression of glial fibrillary acidic protein (gfap), an activated astrocyte marker, produced during the course of hsv-1 infection in astrocytes, was reversed in the presence of 1c1 and 1c3. |
2000-05-04 |
2023-08-12 |
mouse |
| M Zhou, G P Schools, H K Kimelber. GFAP mRNA positive glia acutely isolated from rat hippocampus predominantly show complex current patterns. Brain research. Molecular brain research. vol 76. issue 1. 2000-04-24. PMID:10719222. |
they have been speculated to be an immature astrocyte because, although these cells show positive staining for the predominantly astrocytic marker s 100beta, it has not been possible to show staining for the commonly accepted mature astrocytic marker, glial fibrillary acidic protein (gfap). |
2000-04-24 |
2023-08-12 |
mouse |
| M Yanagisawa, K Nakashima, H Arakawa, K Ikenaka, K Yoshida, T Kishimoto, T Hisatsune, T Tag. Astrocyte differentiation of fetal neuroepithelial cells by interleukin-11 via activation of a common cytokine signal transducer, gp130, and a transcription factor, STAT3. Journal of neurochemistry. vol 74. issue 4. 2000-04-11. PMID:10737606. |
this differentiation process is totally dependent on the gp130-mediated signal-transduction pathway involving activation of a latent cytoplasmic transcription factor, stat3 (for signal transducer and activator of transcription 3), because (a) il-11-induced astrocyte differentiation is not observed when neuroepithelial cells prepared from gp130-deficient mice were used, (b) stimulation of neuroepithelial cells by il-11 rapidly induces tyrosine-phosphorylation of stat3, and (c) transfection of neuroepithelial cells with a dominant-negative form of stat3 inhibits il-11-induced activation of the gfap gene promoter. |
2000-04-11 |
2023-08-12 |
mouse |
| P L Golden, W M Pardridg. Brain microvascular P-glycoprotein and a revised model of multidrug resistance in brain. Cellular and molecular neurobiology. vol 20. issue 2. 2000-03-21. PMID:10696508. |
however, recent studies have been performed with human brain microvessels and double-labeling confocal microscopy using (a) the mrk16 antibody to human p-glycoprotein, (b) an antiserum to glial fibrillary acidic protein (gfap), an astrocyte foot process marker, or (c) an antiserum to the glut1 glucose transporter, a brain endothelial plasma membrane marker. |
2000-03-21 |
2023-08-12 |
human |
| C P Yao, J W Allen, M Aschne. Metallothioneins attenuate methylmercury-induced neurotoxicity in cultured astrocytes and astrocytoma cells. Annals of the New York Academy of Sciences. vol 890. 2000-03-15. PMID:10668428. |
metallothionein-i (mt-i) was expressed in neonatal rat primary astrocyte cultures and an astrocytoma cell line by pgfap-mt-i plasmid transfection under the control of the astrocyte-specific glial fibrillary acidic protein (gfap) promoter. |
2000-03-15 |
2023-08-12 |
rat |
| J Karl, C Gottfried, F Tramontina, P Dunkley, R Rodnight, C A Gonçalve. GFAP phosphorylation studied in digitonin-permeabilized astrocytes: standardization of conditions. Brain research. vol 853. issue 1. 2000-03-07. PMID:10627305. |
phosphorylation of gfap has been investigated in brain slices, astrocyte cultures, cytoskeletal fractions and purified systems. |
2000-03-07 |
2023-08-12 |
Not clear |
| Q Yan, E H Sage, A E Hendrickso. SPARC is expressed by ganglion cells and astrocytes in bovine retina. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society. vol 46. issue 1. 2000-03-06. PMID:10712100. |
muller cells displayed no immunoreactivity, but sparc was present in retinal astrocytes that were identified by the astrocyte marker glial fibrillary acidic protein (gfap). |
2000-03-06 |
2023-08-12 |
cattle |