| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| G J Harry, T J Schmitt, Z Gong, H Brown, N Zawia, H L Evan. Lead-induced alterations of glial fibrillary acidic protein (GFAP) in the developing rat brain. Toxicology and applied pharmacology. vol 139. issue 1. 1996-08-21. PMID:8685912. |
as demonstrated by gfap immunoreactivity, these lead-induced elevations were not associated with astrocyte hypertrophy. |
1996-08-21 |
2023-08-12 |
rat |
| Z Gong, A R Little, H el-Fawal, H L Evan. Trimethyl lead neurotoxicity in the rat: changes in glial fibrillary acidic protein (GFAP). Arhiv za higijenu rada i toksikologiju. vol 46. issue 4. 1996-08-07. PMID:8670008. |
the results indicate that gfap may be used to indicate the role of the astrocyte in the neurotoxicity of tmpb. |
1996-08-07 |
2023-08-12 |
rat |
| F Y Sun, A I Fade. Pretreatment with antisense oligodeoxynucleotides directed against the NMDA-R1 receptor enhances survival and behavioral recovery following traumatic brain injury in rats. Brain research. vol 693. issue 1-2. 1996-07-31. PMID:8653404. |
although cell counts in hippocampus did not differ between treatment groups, astrocyte activation as reflected by glial fibrillary astrocytic protein (gfap) immunocytochemistry was significantly reduced in antisense treated animals. |
1996-07-31 |
2023-08-12 |
rat |
| K Sugaya, M Chouinard, R Greene, M Robbins, D Personett, C Kent, M Gallagher, M McKinne. Molecular indices of neuronal and glial plasticity in the hippocampal formation in a rodent model of age-induced spatial learning impairment. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 16. issue 10. 1996-06-21. PMID:8627377. |
the mrnas for the neuronal form of nitric oxide synthase and for the astrocyte marker glial fibrillary acidic protein (gfap) were elevated in the hippocampus in correlation with the extent of learning impairment. |
1996-06-21 |
2023-08-12 |
human |
| T Wyss-Coray, E Masliah, S M Toggas, E M Rockenstein, M J Brooker, H S Lee, L Muck. Dysregulation of signal transduction pathways as a potential mechanism of nervous system alterations in HIV-1 gp120 transgenic mice and humans with HIV-1 encephalitis. The Journal of clinical investigation. vol 97. issue 3. 1996-05-29. PMID:8609236. |
because alterations of astrocyte functions could contribute to neuronal impairment, we compared brains of gp120 transgenic mice and gp120-transfected c6 astrocytoma cells with controls and found that gp120 induced a prominent elevation of steady state gfap mrna levels, primarily due to transcript stabilization. |
1996-05-29 |
2023-08-12 |
mouse |
| A Selvín-Testa, C F Loidl, E M López, F Capani, J J López-Costa, J Pecci-Saavedr. Prolonged lead exposure modifies astrocyte cytoskeletal proteins in the rat brain. Neurotoxicology. vol 16. issue 3. 1996-03-18. PMID:8584272. |
immunohistochemical staining for glial fibrillar acidic protein (gfap) and vimentin were used to evaluate astrocyte response. |
1996-03-18 |
2023-08-12 |
rat |
| T R Guilarte, A C Kuhlmann, J P O'Callaghan, R C Micel. Enhanced expression of peripheral benzodiazepine receptors in trimethyltin-exposed rat brain: a biomarker of neurotoxicity. Neurotoxicology. vol 16. issue 3. 1996-03-18. PMID:8584276. |
this pattern is very similar to that observed for levels of the astrocyte intermediate filament protein, gfap. |
1996-03-18 |
2023-08-12 |
human |
| F Mahe. Immunolocalization of GLUT1 and GLUT3 glucose transporters in primary cultured neurons and glia. Journal of neuroscience research. vol 42. issue 4. 1996-03-05. PMID:8568932. |
glut1, but not glut3, was detected in glial fibrillary acidic protein (gfap)-positive astrocytes present in mixed neuronal-glial cultures derived from cerebellum and cerebral cortex, as well as in cortical astrocyte cultures. |
1996-03-05 |
2023-08-12 |
rat |
| Y Miyoshi, I Date, T Ono, T Imaoka, S Asari, T Ohmoto, H Iwat. [Encapsulated dopamine-secreting cells transplanted into the brain: a possible therapy for Parkinson's disease]. No shinkei geka. Neurological surgery. vol 24. issue 1. 1996-02-27. PMID:8559262. |
the degree of glial fibrillary acidic protein (gfap) positive astrocyte density around the microcapsules was similar to that around injection tracks. |
1996-02-27 |
2023-08-12 |
rat |
| M Schroeter, K Schiene, M Kraemer, G Hagemann, H Weigel, U T Eysel, O W Witte, G Stol. Astroglial responses in photochemically induced focal ischemia of the rat cortex. Experimental brain research. vol 106. issue 1. 1996-02-12. PMID:8542965. |
astrocyte activation was studied at various time points by immunocytochemistry for glial fibrillary acidic protein (gfap) and vimentin (vim). |
1996-02-12 |
2023-08-12 |
rat |
| P F Bartlett, L R Richards, T J Kilpatrick, P S Talman, K A Bailey, G J Brooker, R Dutton, S Koblar, V Nurcombe, M For. Regulation of neural precursor differentiation in the embryonic and adult forebrain. Clinical and experimental pharmacology & physiology. vol 22. issue 8. 1995-12-19. PMID:7586713. |
precursors restricted to the astrocyte cell lineage can be stimulated by epidermal growth factor or fgf-2; however, the differentiation into gfap positive astrocytes appears to require a cytokine acting through the leukaemia inhibitory factor beta receptor. |
1995-12-19 |
2023-08-12 |
Not clear |
| V Moro, K Kacem, V Springhetti, J Seylaz, F Lasbenne. Microvessels isolated from brain: localization of muscarinic sites by radioligand binding and immunofluorescent techniques. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 15. issue 6. 1995-12-13. PMID:7593341. |
confocal microscopic observations of gfap and m35 immunoreactivities on free-floating sections showed a high degree of colocalization on astrocyte processes associated with large vessels or capillaries. |
1995-12-13 |
2023-08-12 |
rat |
| P S Widdowson, M G Simpson, I Wyatt, E A Loc. [125I]endothelin binding in rat cerebellum is increased following L-2-chloropropionic-acid-induced granule cell necrosis. Peptides. vol 16. issue 5. 1995-12-12. PMID:7479332. |
the increase in [125i]et-1 binding did not parallel the cellular damage and resultant astrocyte proliferation, as measured by gfap immunoreactivity, which was primarily confined to the granular layer of the cerebellar cortex. |
1995-12-12 |
2023-08-12 |
rat |
| R Alemany, G Olmos, P V Escribá, A Menargues, R Obach, J A García-Sevill. LSL 60101, a selective ligand for imidazoline I2 receptors, on glial fibrillary acidic protein concentration. European journal of pharmacology. vol 280. issue 2. 1995-12-07. PMID:7589187. |
these data indicate that glial imidazoline i2 receptors may have a direct physiological function related to gfap expression and that lsl 60101 could be a good tool for the study of the implication of these receptors on astrocyte activation and neuronal regeneration. |
1995-12-07 |
2023-08-12 |
rat |
| I Jalenques, E Albuisson, G Despres, R Roman. Distribution of glial fibrillary acidic protein (GFAP) in the cochlear nucleus of adult and aged rats. Brain research. vol 686. issue 2. 1995-11-30. PMID:7583287. |
the increase in gfap immunoreactivity was related to an increase of both gfap positive astrocyte number and processes. |
1995-11-30 |
2023-08-12 |
rat |
| E Galea, P Dupouey, D L Feinstei. Glial fibrillary acidic protein mRNA isotypes: expression in vitro and in vivo. Journal of neuroscience research. vol 41. issue 4. 1995-11-24. PMID:7473876. |
gfap-beta was also detected in primary rat astrocyte cultures, where it constituted approximately 5% of the total gfap mrna, as well as in rna samples prepared from normal rat cerebral cortex, and from hamster and human brain. |
1995-11-24 |
2023-08-12 |
human |
| E Galea, P Dupouey, D L Feinstei. Glial fibrillary acidic protein mRNA isotypes: expression in vitro and in vivo. Journal of neuroscience research. vol 41. issue 4. 1995-11-24. PMID:7473876. |
in astrocyte cultures, the relative levels of gfap-alpha and -beta mrnas were differentially regulated by exposure to interferon-gamma (10 to 25 units/ml), which caused an increase in gfap-beta levels while at the same time no change or a small decrease in total gfap levels. |
1995-11-24 |
2023-08-12 |
human |
| A S Fix, K A Wightman, J P O'Callagha. Reactive gliosis induced by MK-801 in the rat posterior cingulate/retrosplenial cortex: GFAP evaluation by sandwich ELISA and immunocytochemistry. Neurotoxicology. vol 16. issue 2. 1995-10-30. PMID:7566683. |
the present studies evaluated the astrocyte response with a sandwich format enzyme-linked immunosorbant assay (elisa) for glial fibrillary acidic protein (gfap), the major intermediate filament protein in astrocytes. |
1995-10-30 |
2023-08-12 |
rat |
| F Hajós, A Csilla. The remote astroglial response (RAR): a holistic approach for evaluating the effects of lesions of the central nervous system. Neurochemical research. vol 20. issue 5. 1995-09-21. PMID:7643962. |
this showed that synaptic degeneration triggered an up-regulation of gfap synthesis in the perisynaptic astrocyte processes as a second, cytoskeletal phase of the astrocyte reaction. |
1995-09-21 |
2023-08-12 |
rat |
| G L Yao, H Kiyam. Colchicine induces the GAP-43 gene expression in rat hypothalamus. Brain research. Molecular brain research. vol 30. issue 2. 1995-09-13. PMID:7637588. |
since the positive cell number and shape initially suggested that these were neurons or astrocytes, double labeling in situ hybridization using both radioactive (for the detection of gfap mrna as a marker of astrocyte) and non-radioactive (for the detection of gap-43 mrna) probes was carried out. |
1995-09-13 |
2023-08-12 |
rat |