| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hassan Marzban, Maryam Rahimi-Balaei, Richard Hawke. Early trigeminal ganglion afferents enter the cerebellum before the Purkinje cells are born and target the nuclear transitory zone. Brain structure & function. vol 224. issue 7. 2020-02-18. PMID:31256239. |
double immunostaining for naa and markers of the different domains in the cerebellar primordium reveal that afferents first target the nuclear transitory zone (e9-e10), and only later (e10-e11) are the axons, either collaterals from the trigeminal ganglion or a new afferent source (e.g., vestibular ganglia), seen in the purkinje cell plate. |
2020-02-18 |
2023-08-13 |
mouse |
| Shintaro Saegusa, Masahiro Fukaya, Wataru Kakegawa, Manabu Tanaka, Osamu Katsumata, Takeyuki Sugawara, Yoshinobu Hara, Makoto Itakura, Tadashi Okubo, Toshiya Sato, Michisuke Yuzaki, Hiroyuki Sakagam. Mice lacking EFA6C/Psd2, a guanine nucleotide exchange factor for Arf6, exhibit lower Purkinje cell synaptic density but normal cerebellar motor functions. PloS one. vol 14. issue 5. 2020-02-11. PMID:31095630. |
mice lacking efa6c/psd2, a guanine nucleotide exchange factor for arf6, exhibit lower purkinje cell synaptic density but normal cerebellar motor functions. |
2020-02-11 |
2023-08-13 |
mouse |
| Sung Min Nam, Jin Seok Seo, Tae-Hun Go, Sang-Soep Nahm, Byung-Joon Chan. Ascorbic Acid Supplementation Prevents the Detrimental Effects of Prenatal and Postnatal Lead Exposure on the Purkinje Cell and Related Proteins in the Cerebellum of Developing Rats. Biological trace element research. vol 190. issue 2. 2020-02-04. PMID:30488169. |
ascorbic acid supplementation prevents the detrimental effects of prenatal and postnatal lead exposure on the purkinje cell and related proteins in the cerebellum of developing rats. |
2020-02-04 |
2023-08-13 |
rat |
| Regina T Martuscello, Elan D Louis, Phyllis L Faus. A Stainless Protocol for High Quality RNA Isolation from Laser Capture Microdissected Purkinje Cells in the Human Post-Mortem Cerebellum. Journal of visualized experiments : JoVE. issue 143. 2020-01-24. PMID:30735198. |
the purkinje cell of the cerebellum is a good candidate for stainless visualization, due to its size and characteristic location. |
2020-01-24 |
2023-08-13 |
human |
| Katarzyna O Rojek, Joanna Krzemień, Hubert Doleżyczek, Paweł M Boguszewski, Leszek Kaczmarek, Witold Konopka, Marcin Rylski, Jacek Jaworski, Lars Holmgren, Tomasz J Prószyńsk. Amot and Yap1 regulate neuronal dendritic tree complexity and locomotor coordination in mice. PLoS biology. vol 17. issue 5. 2019-12-16. PMID:31042703. |
the conditional deletion of amot and yap1 in neurons led to a decrease in the complexity of purkinje cell dendritic trees, abnormal cerebellar morphology, and impairments in motor coordination. |
2019-12-16 |
2023-08-13 |
mouse |
| Visou Ady, Brenda Toscano-Márquez, Moushumi Nath, Philip K Chang, Jeanette Hui, Anna Cook, François Charron, Roxanne Larivière, Bernard Brais, R Anne McKinney, Alanna J Wat. Altered synaptic and firing properties of cerebellar Purkinje cells in a mouse model of ARSACS. The Journal of physiology. vol 596. issue 17. 2019-12-11. PMID:29928778. |
autosomal recessive spastic ataxia of charlevoix-saguenay (arsacs) is an early-onset neurodegenerative human disease characterized in part by ataxia and purkinje cell loss in anterior cerebellar lobules. |
2019-12-11 |
2023-08-13 |
mouse |
| Kohki Konishi, Masafumi Mimura, Takao Nonaka, Ichiro Sase, Hideo Nishioka, Mitsuo Sug. Practical method of cell segmentation in electron microscope image stack using deep convolutional neural network☆. Microscopy (Oxford, England). vol 68. issue 4. 2019-12-06. PMID:31220299. |
we segmented a cerebellar purkinje cell from an image stack of a mouse cerebellum cortex in less than two working days, which is much shorter than that of the conventional method. |
2019-12-06 |
2023-08-13 |
mouse |
| Alicia K Au, Yaming Chen, Lina Du, Craig M Smith, Mioara D Manole, Sirine A Baltagi, Charleen T Chu, Rajesh K Aneja, Hülya Bayır, Patrick M Kochanek, Robert S B Clar. Ischemia-induced autophagy contributes to neurodegeneration in cerebellar Purkinje cells in the developing rat brain and in primary cortical neurons in vitro. Biochimica et biophysica acta. vol 1852. issue 9. 2019-11-20. PMID:26071643. |
increased autophagy/mitophagy is thought to contribute to cerebellar dysfunction in purkinje cell degeneration mice. |
2019-11-20 |
2023-08-13 |
mouse |
| Alicia K Au, Yaming Chen, Lina Du, Craig M Smith, Mioara D Manole, Sirine A Baltagi, Charleen T Chu, Rajesh K Aneja, Hülya Bayır, Patrick M Kochanek, Robert S B Clar. Ischemia-induced autophagy contributes to neurodegeneration in cerebellar Purkinje cells in the developing rat brain and in primary cortical neurons in vitro. Biochimica et biophysica acta. vol 1852. issue 9. 2019-11-20. PMID:26071643. |
treatment with atg7 sirna: 1) reduced atg7 protein expression in the cerebellum by 56%; 2) prevented the typical ischemia-induced formation of lc3-ii in the cerebellum 24h after asphyxial cardiac arrest; 3) improved performance on the beam-balance apparatus on days 1-5; and 4) increased calbindin-labeled purkinje cell survival assessed on day 14. |
2019-11-20 |
2023-08-13 |
mouse |
| Osamu Kotani, Tadaki Suzuki, Masaru Yokoyama, Naoko Iwata-Yoshikawa, Noriko Nakajima, Hironori Sato, Hideki Hasegawa, Fumihiro Taguchi, Hiroyuki Shimizu, Noriyo Nagat. Intracerebral Inoculation of Mouse-Passaged Saffold Virus Type 3 Affects Cerebellar Development in Neonatal Mice. Journal of virology. vol 90. issue 21. 2019-11-20. PMID:27581974. |
intracerebral inoculation of either the original or the passaged strain affected brain purkinje cell dendrites, and a high titer of the passaged strain induced cerebellar hypoplasia in neonatal mice. |
2019-11-20 |
2023-08-13 |
mouse |
| Samah Kandeel, Naema Mahmoud Elhosary, Mona Mohamed Abo El-Noor, Mohamed Balah. Corrigendum to "Electric injury-induced Purkinje cell apoptosis in rat cerebellum: Histological and immunohistochemical stud" [J. Chem. Neuroanat., 81 (2017) 87-96]. Journal of chemical neuroanatomy. vol 82. 2019-11-20. PMID:28558919. |
corrigendum to "electric injury-induced purkinje cell apoptosis in rat cerebellum: histological and immunohistochemical stud" [j. chem. |
2019-11-20 |
2023-08-13 |
rat |
| I. Torres-Aleman, S. Pons, F. F. Santos-Benit. Survival of Purkinje Cells in Cerebellar Cultures is Increased by Insulin-like Growth Factor I. The European journal of neuroscience. vol 4. issue 9. 2019-11-20. PMID:12106309. |
we conclude that igf-i is a specific promoter of purkinje cell survival and that its effects differ from those produced by bfgf in fetal cerebellar cultures. |
2019-11-20 |
2023-08-12 |
rat |
| I. Torres-Aleman, S. Pons, F. F. Santos-Benit. Survival of Purkinje Cells in Cerebellar Cultures is Increased by Insulin-like Growth Factor I. The European journal of neuroscience. vol 4. issue 9. 2019-11-20. PMID:12106309. |
these findings reinforce our hypothesis that the purkinje cell is a target neuron for igf-i action in the developing cerebellum. |
2019-11-20 |
2023-08-12 |
rat |
| Andrew M. Batchelor, John Garthwait. GABAB Receptors in the Parallel Fibre Pathway of Rat Cerebellum. The European journal of neuroscience. vol 4. issue 11. 2019-11-20. PMID:12106411. |
we conclude that, at least in the immature rat, there are gabab receptors on purkinje cell dendrites and that these receptors can be activated following parallel fibre stimulation; there are also gabab receptors on presynaptic terminals within the molecular layer of immature and adult cerebellum that, when stimulated, inhibit transmitter release. |
2019-11-20 |
2023-08-12 |
rat |
| David J. Linden, John A. Conno. Long-term Depression of Glutamate Currents in Cultured Cerebellar Purkinje Neurons Does Not Require Nitric Oxide Signalling. The European journal of neuroscience. vol 4. issue 1. 2019-11-20. PMID:12106437. |
cerebellar long-term depression (ltd) is produced when conjunctive stimulation of parallel fibre (pf) and climbing fibre (cf) inputs to a purkinje neuron (pn) results in a prolonged decrease in the strength of the pf - pn synapse. |
2019-11-20 |
2023-08-12 |
Not clear |
| Yeming Yang, Kuanxiang Sun, Wenjing Liu, Lin Zhang, Kun Peng, Shanshan Zhang, Shujin Li, Mu Yang, Zhilin Jiang, Fang Lu, Xianjun Zh. Disruption of Tmem30a results in cerebellar ataxia and degeneration of Purkinje cells. Cell death & disease. vol 9. issue 9. 2019-11-15. PMID:30185775. |
to investigate the role of tmem30a in the cerebellum, we developed a tmem30a purkinje cell (pc)-specific knockout (ko) mouse model. |
2019-11-15 |
2023-08-13 |
mouse |
| Hermina Nedelescu, Mohamed Abdelhack, Arwel T Pritchar. Regional differences in Purkinje cell morphology in the cerebellar vermis of male mice. Journal of neuroscience research. vol 96. issue 9. 2019-11-11. PMID:29319237. |
regional differences in purkinje cell morphology in the cerebellar vermis of male mice. |
2019-11-11 |
2023-08-13 |
mouse |
| Michela Ripolone, Valeria Lucchini, Dario Ronchi, Gigliola Fagiolari, Andreina Bordoni, Francesco Fortunato, Stefania Mondello, Sara Bonato, Mirella Meregalli, Yvan Torrente, Stefania Corti, Giacomo P Comi, Maurizio Moggio, Monica Sciacc. Purkinje cell COX deficiency and mtDNA depletion in an animal model of spinocerebellar ataxia type 1. Journal of neuroscience research. vol 96. issue 9. 2019-11-11. PMID:30113722. |
sca1 transgenic mice develop clinical features in the early life stages (around 5 weeks of age) presenting pathological cerebellar signs with concomitant progressive purkinje neuron atrophy and relatively little cell loss; this evidence suggests that the sca1 phenotype is not the result of cell death per se, but a possible effect of cellular dysfunction that occurs before neuronal demise. |
2019-11-11 |
2023-08-13 |
mouse |
| Rong-Jun Ni, Zhao-Huan Huang, Peng-Hao Luo, Xiao-Hong Ma, Tao Li, Jiang-Ning Zho. The tree shrew cerebellum atlas: Systematic nomenclature, neurochemical characterization, and afferent projections. The Journal of comparative neurology. vol 526. issue 17. 2019-10-28. PMID:30155886. |
moreover, distributive maps of calbindin-immunoreactive (-ir) cells in the purkinje cell layer of the cerebellum of tree shrews were depicted using coronal, sagittal, and horizontal schematics. |
2019-10-28 |
2023-08-13 |
human |
| Daniel T Daly, Michael Arie. A novel cerebellar commissure and other myelinated axons in the Purkinje cell layer of a pond turtle (Trachemys scripta elegans). The Journal of comparative neurology. vol 526. issue 17. 2019-10-28. PMID:30173417. |
a novel cerebellar commissure and other myelinated axons in the purkinje cell layer of a pond turtle (trachemys scripta elegans). |
2019-10-28 |
2023-08-13 |
Not clear |