| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| P Whitworth, D A Kendal. Effects of lithium on inositol phospholipid hydrolysis and inhibition of dopamine D1 receptor-mediated cyclic AMP formation by carbachol in rat brain slices. Journal of neurochemistry. vol 53. issue 2. 1989-08-25. PMID:2545820. |
the in vitro and ex vivo effects of lithium on muscarinic cholinergic inositol phospholipid hydrolysis and muscarinic cholinergic inhibition of dopamine d1-receptor-stimulated cyclic amp formation were examined in rat brain slices. |
1989-08-25 |
2023-08-11 |
rat |
| P Demol, H J Ruoff, T R Weihrauc. Rational pharmacotherapy of gastrointestinal motility disorders. European journal of pediatrics. vol 148. issue 6. 1989-08-25. PMID:2663504. |
in this review the complex situation is described particularly in relation to receptor populations (cholinergic, adrenergic, dopamine, histamine, 5-hydroxytryptamine, opioid, gamma-aminobutyric acid (gaba), prostanoid and dihydropyridine receptors), therapeutic aspects of drugs and their usefulness in children. |
1989-08-25 |
2023-08-11 |
Not clear |
| J L Cumming. Intellectual impairment in Parkinson's disease: clinical, pathologic, and biochemical correlates. Journal of geriatric psychiatry and neurology. vol 1. issue 1. 1989-08-25. PMID:2908099. |
neuropathologic and neurochemical observations demonstrate that pd is a heterogeneous disorder: the classic subcortical pathology with dopamine deficiency may be complicated by atrophy of nucleus basalis and superimposed cortical cholinergic deficits, and a few patients have the histopathologic hallmarks of alzheimer's disease. |
1989-08-25 |
2023-08-11 |
Not clear |
| S J Boyson, P McGonigle, G R Luthin, B B Wolfe, P B Molinof. Effects of chronic administration of neuroleptic and anticholinergic agents on densities of D2 dopamine and muscarinic cholinergic receptors in rat striatum. The Journal of pharmacology and experimental therapeutics. vol 244. issue 3. 1989-08-10. PMID:2908050. |
effects of chronic administration of neuroleptic and anticholinergic agents on densities of d2 dopamine and muscarinic cholinergic receptors in rat striatum. |
1989-08-10 |
2023-08-11 |
rat |
| W K Debinski, O G Kuche. Responsiveness of noradrenergic neurons in rat experimental hypertension. Hypertension (Dallas, Tex. : 1979). vol 13. issue 6 Pt 2. 1989-08-08. PMID:2737717. |
although endogenous dihydroxyphenylacetic acid content and baseline tyrosine incorporation into dihydroxyphenylacetic acid were lower in 4-week-old spontaneously hypertensive rats than in age-matched wistar-kyoto rats, cholinergic stimulation increased labeled dopamine and dihydroxyphenylacetic acid generation significantly more in juvenile spontaneously hypertensive rats. |
1989-08-08 |
2023-08-11 |
rat |
| A B Norman, M T Borchers, T J Wachendorf, A L Price, P R Sanber. Loss of D1 and D2 dopamine receptors and muscarinic cholinergic receptors in rat brain following in vitro polytron homogenization. Brain research bulletin. vol 22. issue 4. 1989-08-01. PMID:2660951. |
loss of d1 and d2 dopamine receptors and muscarinic cholinergic receptors in rat brain following in vitro polytron homogenization. |
1989-08-01 |
2023-08-11 |
rat |
| K Niijima, M Yoshid. Activation of mesencephalic dopamine neurons by chemical stimulation of the nucleus tegmenti pedunculopontinus pars compacta. Brain research. vol 451. issue 1-2. 1989-07-31. PMID:3251582. |
these facts indicate: (1) the tpc-derived circling behavior is mediated by the dopamine system, (2) the chemical stimulation of tpc by ka might produce an activation of midbrain dopamine neurons by excitatory tpc efferents to the dopamine neurons and enhance the dopamine turnover in the nucleus accumbens as well as in the striatum, (3) the excitatory tpc efferents may be muscarinic cholinergic in accordance with previous reports. |
1989-07-31 |
2023-08-11 |
rat |
| V L Coffin, M B Latranyi, R E Chipki. Acute extrapyramidal syndrome in Cebus monkeys: development mediated by dopamine D2 but not D1 receptors. The Journal of pharmacology and experimental therapeutics. vol 249. issue 3. 1989-07-21. PMID:2567351. |
furthermore, the eps is probably due to the selective blockade of dopamine d2 receptors with its associated enhancement of cholinergic neurotransmission. |
1989-07-21 |
2023-08-11 |
monkey |
| J De Keyser, H Walraevens, J P De Backer, G Ebinger, G Vauqueli. D2 dopamine receptors in the human brain: heterogeneity based on differences in guanine nucleotide effect on agonist binding, and their presence on corticostriatal nerve terminals. Brain research. vol 484. issue 1-2. 1989-06-15. PMID:2523750. |
compared to the intact side, d2 receptor densities in striata from the lesioned side were reduced by 46-65%, whereas the densities of the muscarinic cholinergic receptors, dopamine uptake sites, and d1 dopamine receptors were unchanged. |
1989-06-15 |
2023-08-11 |
human |
| E Meller, A Enz, M Goldstei. Absence of receptor reserve at striatal dopamine receptors regulating cholinergic neuronal activity. European journal of pharmacology. vol 155. issue 1-2. 1989-06-06. PMID:2907486. |
absence of receptor reserve at striatal dopamine receptors regulating cholinergic neuronal activity. |
1989-06-06 |
2023-08-11 |
rat |
| T Wichmann, K Wictorin, A Björklund, K Stark. Release of acetylcholine and its dopaminergic control in slices from striatal grafts in the ibotenic acid-lesioned rat striatum. Naunyn-Schmiedeberg's archives of pharmacology. vol 338. issue 6. 1989-05-31. PMID:3149721. |
functional d2-receptors are present on graft cholinergic cells, but are not activated by endogenous dopamine under the present in vitro conditions. |
1989-05-31 |
2023-08-11 |
rat |
| M J Iadarola, M M Mouradia. Decrease in a proenkephalin peptide in cerebrospinal fluid in Huntington's disease and progressive supranuclear palsy. Brain research. vol 479. issue 2. 1989-04-28. PMID:2522341. |
the decrease in progressive supranuclear palsy, a disease in which dopamine neurons degenerate but enkephalin levels in the basal ganglia are reportedly not decreased, may reflect a functional decline in enkephalinergic neuronal activity secondary to a striatal cholinergic deficit. |
1989-04-28 |
2023-08-11 |
Not clear |
| S Iyengar, A Hausler, H S Kim, M Marien, C A Altar, P L Woo. The dopamine autoreceptor agonist, (+/-)-trans-1,3,4,4a5,10b-hexahydro-4-propyl-2H [1]benzopyrano [3,4-b] pyridin-9-ol hydrochloride (CGS 15855A), modulates striatal dopamine metabolism and prolactin release. Neuropharmacology. vol 28. issue 1. 1989-04-28. PMID:2522597. |
these data suggest that cgs 15855a is a selective dopamine autoreceptor agonist which preferentially stimulates d2 receptors on lactotrophs and dopaminergic neurons as compared to d2 receptors on cholinergic interneurons in the striatum. |
1989-04-28 |
2023-08-11 |
Not clear |
| A Hamik, S J Peroutk. 1-(m-chlorophenyl)piperazine (mCPP) interactions with neurotransmitter receptors in the human brain. Biological psychiatry. vol 25. issue 5. 1989-04-17. PMID:2537663. |
mcpp is less potent at alpha 1- and beta-adrenergic, dopamine, and muscarinic cholinergic receptors (ic50 values 2500-24,000 nm). |
1989-04-17 |
2023-08-11 |
human |
| T Wetterlin. [Alzheimer's disease. Review of the current status of research]. Fortschritte der Neurologie-Psychiatrie. vol 57. issue 1. 1989-03-27. PMID:2563716. |
the neuropathological changes are not limited to the grey matter and cholinergic system, but the white matter and some neurotransmitter systems (noradrenaline, dopamine, serotonin and somatostatin) are affected too. |
1989-03-27 |
2023-08-11 |
Not clear |
| A S Undie, E Friedma. Differences in the cataleptogenic actions of SCH23390 and selected classical neuroleptics. Psychopharmacology. vol 96. issue 3. 1989-03-23. PMID:2906152. |
it is inferred that sch23390 differs from the classical neuroleptics in its mechanism of cataleptogenicity, that there is a cholinergic link with the d1 dopamine system, and further, that there may be a difference in the nature or impact of the cholinergic interaction with the d1 and d2 dopamine systems. |
1989-03-23 |
2023-08-11 |
rat |
| L Pierot, C Desnos, J Blin, R Raisman, D Scherman, F Javoy-Agid, M Ruberg, Y Agi. D1 and D2-type dopamine receptors in patients with Parkinson's disease and progressive supranuclear palsy. Journal of the neurological sciences. vol 86. issue 2-3. 1989-03-22. PMID:2975699. |
the densities of d1- and d2-type dopamine receptors were measured with [3h]sch23390 and [3h]spiperone, in the caudate nucleus and putamen of a large series of patients with parkinson's disease or progressive supranuclear palsy, in relation to markers of dopaminergic and cholinergic innervation of the striatum ([3h]dihydrotetrabenazine binding and choline acetyltransferase activity). |
1989-03-22 |
2023-08-11 |
Not clear |
| T Aimoto, B H Rohde, G C Chiou, J K Laube. N-acetyltransferase activity and melatonin level in the eyes of glaucomatous chickens. Journal of ocular pharmacology. vol 1. issue 2. 1989-03-17. PMID:3880072. |
no statistical differences in choline acetyltransferase activity, adrenergic transmitter levels or dopamine concentrations could be found in tissues of liag eyes vs control eyes, indicating that cholinergic, adrenergic and dopaminergic mechanisms are probably not involved in liag. |
1989-03-17 |
2023-08-11 |
human |
| J G Hensler, M L Dubocovic. GABAergic modulation of D-1 dopamine receptor-mediated 3H-acetylcholine release from rabbit retina. Naunyn-Schmiedeberg's archives of pharmacology. vol 337. issue 6. 1989-03-02. PMID:3216899. |
picrotoxin and bicuculline (10 microm) increased the spontaneous release of tritium, and potentiated the release of 3h-acetylcholine evoked by 100 microm dopamine consistent with a tonic, inhibitory gabaergic input to the cholinergic amacrine neurons in rabbit retina. |
1989-03-02 |
2023-08-11 |
rabbit |
| L Turski, E A Cavalheiro, Z A Bortolotto, C Ikonomidou-Turski, Z Kleinrok, W A Tursk. Dopamine-sensitive anticonvulsant site in the rat striatum. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 8. issue 11. 1988-12-22. PMID:3183711. |
this work presents evidence that bilateral application of picomole amounts of apomorphine (a dopamine agonist) into the striatum confers protection against seizures produced by pilocarpine (a cholinergic agonist) in rats. |
1988-12-22 |
2023-08-11 |
rat |