| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Zong-Bo Wei, Ye-Feng Yuan, Florence Jaouen, Mei-Sheng Ma, Chan-Juan Hao, Zhe Zhang, Quan Chen, Zengqiang Yuan, Li Yu, Corinne Beurrier, Wei L. SLC35D3 increases autophagic activity in midbrain dopaminergic neurons by enhancing BECN1-ATG14-PIK3C3 complex formation. Autophagy. vol 12. issue 7. 2018-01-16. PMID:27171858. |
loss of slc35d3 in ros (roswell mutant) mice showed a reduction of 11.9% da neurons in the snc and 15.5% da neuron loss in the vta with impaired autophagy. |
2018-01-16 |
2023-08-13 |
mouse |
| Wendy Xin, Nicholas Edwards, Antonello Bonc. VTA dopamine neuron plasticity - the unusual suspects. The European journal of neuroscience. vol 44. issue 12. 2017-11-13. PMID:27711998. |
we summarize the findings within the vta as well as observations made in other brain regions that have important implications for plasticity in general and should be considered in the context of da neuron plasticity. |
2017-11-13 |
2023-08-13 |
Not clear |
| Lei Xiao, Michael F Priest, Jordan Nasenbeny, Ting Lu, Yevgenia Kozorovitski. Biased Oxytocinergic Modulation of Midbrain Dopamine Systems. Neuron. vol 95. issue 2. 2017-09-14. PMID:28669546. |
electrophysiological recordings of da neurons reveal that both the application of oxytocin and optogenetic stimulation of oxytocinergic terminals suffice to increase da neuron activity in the vta but downregulate it in snc. |
2017-09-14 |
2023-08-13 |
Not clear |
| Ekaterina O Morozova, Maxym Myroshnychenko, Denis Zakharov, Matteo di Volo, Boris Gutkin, Christopher C Lapish, Alexey Kuznetso. Contribution of synchronized GABAergic neurons to dopaminergic neuron firing and bursting. Journal of neurophysiology. vol 116. issue 4. 2017-09-05. PMID:27440240. |
in the ventral tegmental area (vta), interactions between dopamine (da) and γ-aminobutyric acid (gaba) neurons are critical for regulating da neuron activity and thus da efflux. |
2017-09-05 |
2023-08-13 |
Not clear |
| Ekaterina O Morozova, Maxym Myroshnychenko, Denis Zakharov, Matteo di Volo, Boris Gutkin, Christopher C Lapish, Alexey Kuznetso. Contribution of synchronized GABAergic neurons to dopaminergic neuron firing and bursting. Journal of neurophysiology. vol 116. issue 4. 2017-09-05. PMID:27440240. |
to provide a mechanistic explanation of how gaba neurons influence da neuron firing, we developed a circuit model of the vta. |
2017-09-05 |
2023-08-13 |
Not clear |
| Barbara Juarez, Ming-Hu Ha. Diversity of Dopaminergic Neural Circuits in Response to Drug Exposure. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 41. issue 10. 2017-08-30. PMID:26934955. |
this review hopes to describe the projection-specific intrinsic characteristics of these subpopulations, the differential afferent inputs onto these vta da neuron subpopulations, and consolidate findings of drug-induced plasticity of vta da neurons and highlight the importance of future projection-based studies of this system. |
2017-08-30 |
2023-08-13 |
Not clear |
| Eric C Zimmerman, Anthony A Grac. The Nucleus Reuniens of the Midline Thalamus Gates Prefrontal-Hippocampal Modulation of Ventral Tegmental Area Dopamine Neuron Activity. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 36. issue 34. 2017-07-17. PMID:27559178. |
previous work suggests that the medial prefrontal cortex (mpfc) exerts a profound influence on vta da neuron firing. |
2017-07-17 |
2023-08-13 |
rat |
| Eric C Zimmerman, Anthony A Grac. The Nucleus Reuniens of the Midline Thalamus Gates Prefrontal-Hippocampal Modulation of Ventral Tegmental Area Dopamine Neuron Activity. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 36. issue 34. 2017-07-17. PMID:27559178. |
here, we used in vivo electrophysiological and behavioral approaches in rats to explore the role of the re in the circuitry governing vta da neuron firing. |
2017-07-17 |
2023-08-13 |
rat |
| Eric C Zimmerman, Anthony A Grac. The Nucleus Reuniens of the Midline Thalamus Gates Prefrontal-Hippocampal Modulation of Ventral Tegmental Area Dopamine Neuron Activity. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 36. issue 34. 2017-07-17. PMID:27559178. |
we show that pharmacological stimulation of the re enhances vta da neuron population activity and amphetamine-induced hyperlocomotion, a behavioral indicator of an over-responsive da system. |
2017-07-17 |
2023-08-13 |
rat |
| Eric C Zimmerman, Anthony A Grac. The Nucleus Reuniens of the Midline Thalamus Gates Prefrontal-Hippocampal Modulation of Ventral Tegmental Area Dopamine Neuron Activity. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 36. issue 34. 2017-07-17. PMID:27559178. |
finally, pharmacological inhibition of ilpfc enhances vta da neuron population activity, but this effect does not occur if re is also inhibited. |
2017-07-17 |
2023-08-13 |
rat |
| Felipe V Gomes, Anthony A Grac. Prefrontal Cortex Dysfunction Increases Susceptibility to Schizophrenia-Like Changes Induced by Adolescent Stress Exposure. Schizophrenia bulletin. vol 43. issue 3. 2017-05-10. PMID:28003467. |
at adulthood, animals were tested for anxiety responses (elevated plus-maze), cognitive function (novel-object recognition test) and dopamine (da) system responsivity (locomotor response to amphetamine and da neuron activity in the ventral tegmental area (vta) using in vivo electrophysiology). |
2017-05-10 |
2023-08-13 |
rat |
| Pauline Belujon, Nicole L Jakobowski, Hannah K Dollish, Anthony A Grac. Withdrawal from Acute Amphetamine Induces an Amygdala-Driven Attenuation of Dopamine Neuron Activity: Reversal by Ketamine. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 41. issue 2. 2016-09-20. PMID:26129677. |
the effects of inactivation of the basolateral amygdala (bla) and ketamine administration on vta da neuron activity and passivity in the modified fst were examined. |
2016-09-20 |
2023-08-13 |
rat |
| Ji Zhang, Beibei Yang, Hongbin Sun, Yan Zhou, Mengdi Liu, Jianhua Ding, Feng Fang, Yi Fan, Gang H. Aquaporin-4 deficiency diminishes the differential degeneration of midbrain dopaminergic neurons in experimental Parkinson's disease. Neuroscience letters. vol 614. 2016-06-29. PMID:26748031. |
here, we further observe that aqp4 deficiency resulted in the same susceptible to mptp between sn da neuron and vta neurons both in acute and chronic pd model. |
2016-06-29 |
2023-08-13 |
mouse |
| Kathryn Hausknecht, Samir Haj-Dahmane, Ying-Ling Shen, Paul Vezina, Cynthia Dlugos, Roh-Yu She. Excitatory synaptic function and plasticity is persistently altered in ventral tegmental area dopamine neurons after prenatal ethanol exposure. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 40. issue 4. 2016-01-05. PMID:25284318. |
in pe animals, we observed a persistent augmentation in calcium-permeable ampa receptor (cp-ampar) expression, indicated by increased rectification and reduced decay time of ampar-mediated excitatory postsynaptic currents (ampar-epscs), enhanced depression of ampar-epscs by naspm (a selective cp-ampar antagonist), and increased glua3 subunits in vta da neuron dendrites. |
2016-01-05 |
2023-08-13 |
rat |
| A Mrejeru, L Martí-Prats, E M Avegno, N L Harrison, D Sulze. A subset of ventral tegmental area dopamine neurons responds to acute ethanol. Neuroscience. vol 290. 2015-12-15. PMID:25660505. |
these findings are consistent with evidence for heterogeneity among midbrain da neurons and provide an anatomical and pharmacological distinction between da neuron sub-populations that will facilitate future mechanistic studies on the actions of etoh in the vta. |
2015-12-15 |
2023-08-13 |
mouse |
| Melissa A Herman, Harpreet Sidhu, David G Stouffer, Max Kreifeldt, David Le, Chelsea Cates-Gatto, Michaelanne B Munoz, Amanda J Roberts, Loren H Parsons, Marisa Roberto, Kevin Wickman, Paul A Slesinger, Candice Conte. GIRK3 gates activation of the mesolimbic dopaminergic pathway by ethanol. Proceedings of the National Academy of Sciences of the United States of America. vol 112. issue 22. 2015-10-13. PMID:25964320. |
these findings support the notion that the subunit composition of vta girk channels is a critical determinant of da neuron sensitivity to drugs of abuse. |
2015-10-13 |
2023-08-13 |
mouse |
| Judith V Schweimer, Gaelle S L Coullon, Jill F Betts, Philip W J Burnet, Sandra J Engle, Nicholas J Brandon, Paul J Harrison, Trevor Shar. Increased burst-firing of ventral tegmental area dopaminergic neurons in D-amino acid oxidase knockout mice in vivo. The European journal of neuroscience. vol 40. issue 7. 2015-06-29. PMID:25040393. |
these data provide the first direct evidence that dao modulates vta da neuron activity, which is of interest for understanding both the glutamatergic regulation of dopamine function and the therapeutic potential of dao inhibitors. |
2015-06-29 |
2023-08-13 |
mouse |
| Judith V Schweimer, Gaelle S L Coullon, Jill F Betts, Philip W J Burnet, Sandra J Engle, Nicholas J Brandon, Paul J Harrison, Trevor Shar. Increased burst-firing of ventral tegmental area dopaminergic neurons in D-amino acid oxidase knockout mice in vivo. The European journal of neuroscience. vol 40. issue 7. 2015-06-29. PMID:25040393. |
the increased da neuron burst-firing probably reflects increased availability of d-serine at vta nmda receptors, but the site, mechanism and mediation of the effect requires further investigation, and may include both direct and indirect processes. |
2015-06-29 |
2023-08-13 |
mouse |
| Brittany Draycott, Michael Loureiro, Tasha Ahmad, Huibing Tan, Jordan Zunder, Steven R Laviolett. Cannabinoid transmission in the prefrontal cortex bi-phasically controls emotional memory formation via functional interactions with the ventral tegmental area. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 39. 2014-11-25. PMID:25253856. |
we report that direct intra-mpfc cb1 activation biphasically modulates spontaneous, subcortical vta da neuron activity in a dose-dependent fashion; while lower doses of a cb1 receptor agonist, win 55,212-2, significantly increased spontaneous firing and bursting rates of vta da neurons, higher doses strongly inhibited spontaneous da neuron activity. |
2014-11-25 |
2023-08-13 |
rat |
| Jordan T Yorgason, Mark J Ferris, Scott C Steffensen, Sara R Jone. Frequency-dependent effects of ethanol on dopamine release in the nucleus accumbens. Alcoholism, clinical and experimental research. vol 38. issue 2. 2014-09-29. PMID:24117706. |
ethanol (etoh) is known to have excitatory effects on dopamine (da) release, with moderate-to-high doses (0.5 to 2.5 g/kg) of acute etoh enhancing da neuron firing rates in the ventral tegmental area (vta) and da levels in the nucleus accumbens (nac). |
2014-09-29 |
2023-08-12 |
Not clear |