| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jue Wang, Samir Haj-Dahmane, Roh-Yu She. Effects of prenatal ethanol exposure on the excitability of ventral tegmental area dopamine neurons in vitro. The Journal of pharmacology and experimental therapeutics. vol 319. issue 2. 2006-12-04. PMID:16905687. |
taken together, the above results indicate that prenatal ethanol exposure-induced reduction in vta da neuron population activity in vivo is not caused by changes in the intrinsic pacemaker activity or other membrane properties and could instead be caused by altered inputs to vta da neurons. |
2006-12-04 |
2023-08-12 |
Not clear |
| Sandra L Morzorati, Rita L Marund. Comparison of VTA dopamine neuron activity in lines of rats selectively bred to prefer or avoid alcohol. Alcoholism, clinical and experimental research. vol 30. issue 6. 2006-09-05. PMID:16737457. |
the present study sought to extend our previous work and include np rats and to determine whether differences in vta da neuron activity could be generalized to other rat lines selected for high and low alcohol preference, namely the high (had) and low (lad) alcohol-drinking rats. |
2006-09-05 |
2023-08-12 |
rat |
| Lachlan Thompson, Perrine Barraud, Elin Andersson, Deniz Kirik, Anders Björklun. Identification of dopaminergic neurons of nigral and ventral tegmental area subtypes in grafts of fetal ventral mesencephalon based on cell morphology, protein expression, and efferent projections. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 25. issue 27. 2006-02-28. PMID:16000637. |
we show that the snpc and vta neuron subtypes in vm grafts can be identified on the basis of their morphology and location within the graft, and their expression of a g-protein-gated inwardly rectifying k+ channel subunit (girk2) and calbindin, respectively, and also that the axonal projections of the two da neuron types are markedly different. |
2006-02-28 |
2023-08-12 |
mouse |
| Kota Ishida, Mikio Murata, Nobuyuki Katagiri, Masago Ishikawa, Kenji Abe, Masatoshi Kato, Iku Utsunomiya, Kyoji Taguch. Effects of beta-phenylethylamine on dopaminergic neurons of the ventral tegmental area in the rat: a combined electrophysiological and microdialysis study. The Journal of pharmacology and experimental therapeutics. vol 314. issue 2. 2005-09-30. PMID:15879004. |
these findings indicate that beta-phenylethylamine inhibits da neuron activity via da d(2) autoreceptors in the rat vta and that this inhibitory effect is mediated by the somatodendritic da release. |
2005-09-30 |
2023-08-12 |
rat |
| D J Lodge, A A Grac. Acute and chronic corticotropin-releasing factor 1 receptor blockade inhibits cocaine-induced dopamine release: correlation with dopamine neuron activity. The Journal of pharmacology and experimental therapeutics. vol 314. issue 1. 2005-08-26. PMID:15784652. |
in addition, the effect of crf1 receptor antagonism on cocaine-induced da overflow in the acb was examined and correlated with da neuron activity in the ventral tegmental area (vta). |
2005-08-26 |
2023-08-12 |
Not clear |
| Qing-Shan Yan, Shi-Zhong Zheng, Shu-E Ya. Involvement of 5-HT1B receptors within the ventral tegmental area in regulation of mesolimbic dopaminergic neuronal activity via GABA mechanisms: a study with dual-probe microdialysis. Brain research. vol 1021. issue 1. 2004-11-08. PMID:15328035. |
intra-tegmental infusion of cp 93129 (20, 40, and 80 microm), a 5-ht1b receptor agonist, increased extracellular da concentrations in a concentration-dependent manner not only in the nacc but also in the vta, indicating increased mesolimbic da neuron activity. |
2004-11-08 |
2023-08-12 |
rat |
| Qing-Shan Yan, Shi-Zhong Zheng, Shu-E Ya. Involvement of 5-HT1B receptors within the ventral tegmental area in regulation of mesolimbic dopaminergic neuronal activity via GABA mechanisms: a study with dual-probe microdialysis. Brain research. vol 1021. issue 1. 2004-11-08. PMID:15328035. |
the results suggest that activation of vta 5-ht1b receptors increases mesolimbic da neuron activities. |
2004-11-08 |
2023-08-12 |
rat |
| Qing-Shan Yan, Shi-Zhong Zheng, Shu-E Ya. Involvement of 5-HT1B receptors within the ventral tegmental area in regulation of mesolimbic dopaminergic neuronal activity via GABA mechanisms: a study with dual-probe microdialysis. Brain research. vol 1021. issue 1. 2004-11-08. PMID:15328035. |
the increased da neuron activity may be associated, at least in part, with the 5-ht1b receptor-mediated inhibition of vta gaba release. |
2004-11-08 |
2023-08-12 |
rat |
| K Choong, R She. Prenatal ethanol exposure alters the postnatal development of the spontaneous electrical activity of dopamine neurons in the ventral tegmental area. Neuroscience. vol 126. issue 4. 2004-10-08. PMID:15207341. |
because da neuron activity matures into adult pattern during postnatal development, it is possible that reduced activity in vta da neurons after prenatal ethanol exposure is caused by impaired postnatal development. |
2004-10-08 |
2023-08-12 |
Not clear |
| Kar-Chan Choong, Roh-Yu She. Methylphenidate restores ventral tegmental area dopamine neuron activity in prenatal ethanol-exposed rats by augmenting dopamine neurotransmission. The Journal of pharmacology and experimental therapeutics. vol 309. issue 2. 2004-06-21. PMID:14724217. |
we have shown previously that reduced ventral tegmental area (vta) da neuron activity in prenatal ethanol-exposed animals can be normalized by da agonist treatment. |
2004-06-21 |
2023-08-12 |
rat |
| Kar-Chan Choong, Roh-Yu She. Methylphenidate restores ventral tegmental area dopamine neuron activity in prenatal ethanol-exposed rats by augmenting dopamine neurotransmission. The Journal of pharmacology and experimental therapeutics. vol 309. issue 2. 2004-06-21. PMID:14724217. |
we observed that reduced vta da neuron activity in prenatal ethanol-exposed animals was normalized by methylphenidate. |
2004-06-21 |
2023-08-12 |
rat |
| Kar-Chan Choong, Roh-Yu She. Methylphenidate restores ventral tegmental area dopamine neuron activity in prenatal ethanol-exposed rats by augmenting dopamine neurotransmission. The Journal of pharmacology and experimental therapeutics. vol 309. issue 2. 2004-06-21. PMID:14724217. |
these observations support our hypothesis that depolarization inactivation is the cause of prenatal ethanol exposure-induced reduction in vta da neuron activity. |
2004-06-21 |
2023-08-12 |
rat |
| Kar-Chan Choong, Roh-Yu She. Methylphenidate restores ventral tegmental area dopamine neuron activity in prenatal ethanol-exposed rats by augmenting dopamine neurotransmission. The Journal of pharmacology and experimental therapeutics. vol 309. issue 2. 2004-06-21. PMID:14724217. |
the normalized vta da neuron activity in prenatal ethanol-exposed animals may contribute to a restoration of da neurotransmission and the therapeutic effect of methylphenidate in attention problems in children with fasd. |
2004-06-21 |
2023-08-12 |
rat |
| François Georges, Gary Aston-Jone. Prolonged activation of mesolimbic dopaminergic neurons by morphine withdrawal following clonidine: participation of imidazoline and norepinephrine receptors. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 28. issue 6. 2003-08-04. PMID:12700697. |
in contrast, pretreatment with a more selective alpha2r agonist, uk14304, did not prevent the inhibition of vta da neuron activity during withdrawal. |
2003-08-04 |
2023-08-12 |
rat |
| Diego Centonze, Alessandro Usiello, Paolo Gubellini, Antonio Pisani, Emiliana Borrelli, Giorgio Bernardi, Paolo Calabres. Dopamine D2 receptor-mediated inhibition of dopaminergic neurons in mice lacking D2L receptors. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 27. issue 5. 2002-12-26. PMID:12431847. |
to identify which isoform is involved in the autoregulation of midbrain da neuron activity, intracellular electrophysiological recordings were performed from substantia nigra and ventral tegmental area neurons of mice lacking either d2l(d2l-/-) or both d2l and d2s receptors (d2-/-). |
2002-12-26 |
2023-08-12 |
mouse |
| Grégory Porras, Vincenzo Di Matteo, Claudia Fracasso, Guillaume Lucas, Philippe De Deurwaerdère, Silvio Caccia, Ennio Esposito, Umberto Spampinat. 5-HT2A and 5-HT2C/2B receptor subtypes modulate dopamine release induced in vivo by amphetamine and morphine in both the rat nucleus accumbens and striatum. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 26. issue 3. 2002-04-02. PMID:11850146. |
)-induced increase in da neuron firing rate in both the ventral tegmental area and the substantia nigra pars compacta was unaffected by sr 46349b (0.1 mg/kg i.v.) |
2002-04-02 |
2023-08-12 |
rat |
| S B Floresco, C L Todd, A A Grac. Glutamatergic afferents from the hippocampus to the nucleus accumbens regulate activity of ventral tegmental area dopamine neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 13. 2001-07-26. PMID:11425919. |
to examine whether this occurs by activation of da neuron firing, the effects of chemical stimulation of the vsub on ventral tegmental area (vta) da neuron activity were examined using extracellular single-unit recordings. |
2001-07-26 |
2023-08-12 |
Not clear |
| S B Floresco, C L Todd, A A Grac. Glutamatergic afferents from the hippocampus to the nucleus accumbens regulate activity of ventral tegmental area dopamine neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 13. 2001-07-26. PMID:11425919. |
these data show that glutamatergic afferents from the vsub to the nac exert a potent excitatory effect on vta da neurons, influencing both da neuron population activity and the regulation of the firing properties of these neurons. |
2001-07-26 |
2023-08-12 |
Not clear |
| S O Castillo, J S Baffi, M Palkovits, D S Goldstein, I J Kopin, J Witta, M A Magnuson, V M Nikode. Dopamine biosynthesis is selectively abolished in substantia nigra/ventral tegmental area but not in hypothalamic neurons in mice with targeted disruption of the Nurr1 gene. Molecular and cellular neurosciences. vol 11. issue 1-2. 1998-08-07. PMID:9608532. |
dopamine (da) was absent in the substantia nigra (sn) and ventral tegmental area (vta) of nurr1-null mice, consistent with absent tyrosine hydroxylase (th), l-aromatic amino acid decarboxylase, and other da neuron markers. |
1998-08-07 |
2023-08-12 |
mouse |
| S Shimada, M Ishikawa, C Tanak. Histochemical mapping of dopamine neurons and fiber pathways in dog mesencephalon. The Journal of comparative neurology. vol 168. issue 4. 1976-09-25. PMID:939821. |
the extensive da neuron system was found to be located in the ventral and medial regions of the mesencephalon; the pars compacta of the substantia nigra, the area almost corresponding to the ventral tegmental area of tsai (which consists of three groups, a caudal, the nucleus parabrachialis pigmentosus, a ventral, the nucleus paranigralis and a rostral, the caudal part of the nucleus tegmentalis ventralis of tsai), the nucleus linearis of the raphe, and the mesencephalic reticular formation. |
1976-09-25 |
2023-08-11 |
dog |