| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M I Oliverio, K Madsen, C F Best, M Ito, N Maeda, O Smithies, T M Coffma. Renal growth and development in mice lacking AT1A receptors for angiotensin II. The American journal of physiology. vol 274. issue 1. 1998-02-23. PMID:9458822. |
by light microscopy with immunohistochemistry, kidneys from agtr1a-(-/-) were essentially normal, with two exceptions: 1) there was marked hypertrophy of the juxtaglomerular apparatus (jga) and proximal expansion of renin-producing cells along the afferent arterioles, and 2) some glomeruli showed evidence of mesangial expansion. |
1998-02-23 |
2023-08-12 |
mouse |
| O Michel, D Heudes, I Lamarre, C Masurier, M Lavau, J Bariety, J Chevalie. Reduction of insulin and triglycerides delays glomerulosclerosis in obese Zucker rats. Kidney international. vol 52. issue 6. 1998-01-12. PMID:9407498. |
acarbose did not modify the hypertrophy of the glomeruli that developed after three months, but slowed down the expansion of the mesangial domain seen in zo. |
1998-01-12 |
2023-08-12 |
rat |
| O Forpomès, C Combe, J Cambar, M Aparici. Cyclosporin-A- and angiotensin-II-induced vasoreactivity in isolated glomeruli and cultured mesangial cells, 4 and 24 h after renal mass reduction: role of vasodilatory prostaglandins. Nephron. vol 76. issue 3. 1997-09-22. PMID:9226236. |
subtotal nephrectomy in the rat is followed by early hypertrophy and functional adaptation of the remnant glomeruli in which mesangial cells seem to play a leading part. |
1997-09-22 |
2023-08-12 |
rat |
| E Takimoto, J Ishida, F Sugiyama, H Horiguchi, K Murakami, A Fukamiz. Hypertension induced in pregnant mice by placental renin and maternal angiotensinogen. Science (New York, N.Y.). vol 274. issue 5289. 1996-12-06. PMID:8875944. |
histopathologic examination revealed uniform enlargement of glomeruli associated with an increase in urinary protein excretion, myocardial hypertrophy, and necrosis and edema in the placenta. |
1996-12-06 |
2023-08-12 |
mouse |
| A Bataillard, N Blanc-Brunat, G Vivier, I Medeiros, B L Zhang, J L Touraine, J Sassar. Antihypertensive effect of thymectomy in Lyon hypertensive rats. Vascular reactivity, renal histology, and sodium excretion. American journal of hypertension. vol 9. issue 2. 1996-11-13. PMID:8924267. |
histological study showed that kidneys from lh rats exhibited arterial wall hypertrophy, segmental hyalinization of the glomeruli, and were infiltrated by mononuclear cells. |
1996-11-13 |
2023-08-12 |
rat |
| L A Godley, J B Kopp, M Eckhaus, J J Paglino, J Owens, H E Varmu. Wild-type p53 transgenic mice exhibit altered differentiation of the ureteric bud and possess small kidneys. Genes & development. vol 10. issue 7. 1996-10-23. PMID:8846920. |
as a result, p53 transgenic kidneys grow to only half of their expected size and contain about half of the normal number of nephrons, with compensatory hypertrophy of the glomeruli. |
1996-10-23 |
2023-08-12 |
mouse |
| H Trachtman, S Futterweit, J Maesaka, C Ma, E Valderrama, A Fuchs, A A Tarectecan, P S Rao, J A Sturman, T H Bole. Taurine ameliorates chronic streptozocin-induced diabetic nephropathy in rats. The American journal of physiology. vol 269. issue 3 Pt 2. 1995-11-02. PMID:7573492. |
this treatment also prevented glomerular hypertrophy, preserved immunohistochemical staining for type iv collagen in glomeruli, and diminished glomerulosclerosis and tubulointerstitial fibrosis in diabetic animals. |
1995-11-02 |
2023-08-12 |
rat |
| K Akaoka, R H White, F Raafa. Glomerular morphometry in childhood reflux nephropathy, emphasizing the capillary changes. Kidney international. vol 47. issue 4. 1995-07-17. PMID:7783408. |
to examine the relative contributions of capillary dilatation and growth in producing hypertrophy, glomeruli contained in unscarred areas of renal biopsies from 19 children with rn were compared with those in 16 children with minimal change nephrotic syndrome and 16 with recurrent hematuria, who were used as controls representing normal childhood growth. |
1995-07-17 |
2023-08-12 |
Not clear |
| S J Shankland, J W Schole. Expression of growth-related protooncogenes during diabetic renal hypertrophy. Kidney international. vol 47. issue 3. 1995-06-22. PMID:7752577. |
accordingly, we studied c-fos, c-jun, and c-myc expression in glomeruli during the rapid phase of glomerular hypertrophy that follows the onset of hyperglycemia in diabetic rats. |
1995-06-22 |
2023-08-12 |
rat |
| R Tanaka, K Sugihara, A Tatematsu, A Fog. Internephron heterogeneity of growth factors and sclerosis--modulation of platelet-derived growth factor by angiotensin II. Kidney international. vol 47. issue 1. 1995-06-01. PMID:7731138. |
we studied the early phase after 5/6 nephrectomy in munich-wistar rats to determine whether treatment with angiotensin ii receptor antagonist (aiira) modulates the expression of platelet-derived growth factor (pdgf) mrna and its protein among the glomeruli which are undergoing progressive hypertrophy and sclerosis. |
1995-06-01 |
2023-08-12 |
rat |
| S Okuda, K Tamaki, T Ando, A Nagashima, M Nakayama, K Fukuda, H Higashi, M Fujishim. Increased expression of Na+/H+ exchanger in the injured renal tissues of focal glomerulosclerosis in rats. Kidney international. vol 46. issue 6. 1995-05-03. PMID:7700022. |
the high salt diet had a hypertrophic and destructive effect on kidney or glomeruli in the adr rats. |
1995-05-03 |
2023-08-12 |
rat |
| S Ishihara, S Inaba, T Okad. [A study on glomerular hypertrophy in various renal disease]. Nihon Jinzo Gakkai shi. vol 36. issue 10. 1995-02-08. PMID:7815744. |
fgs cases showed no relationship between the ratio of obsolescent glomeruli to whole glomeruli and glomerular hypertrophy. |
1995-02-08 |
2023-08-12 |
Not clear |
| R Vienet, J M Grognet, E Ezan, D Lecaque, G Hamon, B Corma. Effect of chronic converting-enzyme inhibition on kidney function of senescent hypertensive rats. Journal of cardiovascular pharmacology. vol 23 Suppl 4. 1995-01-05. PMID:7527097. |
hypertrophy of the glomeruli with a high incidence of glomerulosclerosis was reported in the 21-month-old animals. |
1995-01-05 |
2023-08-12 |
rat |
| M M Schwartz, J Evans, A K Bidan. The mesangium in the long-term remnant kidney model. The Journal of laboratory and clinical medicine. vol 124. issue 5. 1994-12-21. PMID:7964122. |
the normal mesangial clearance function and the absence of mesangial pathology in the hypertrophic remnant glomeruli mitigate against a role for mesangial injury in this form of experimental renal disease. |
1994-12-21 |
2023-08-12 |
rat |
| J Suzuki, N Yoshikawa, H Nakamur. A quantitative analysis of the glomeruli in focal segmental glomerulosclerosis. Pediatric nephrology (Berlin, Germany). vol 8. issue 4. 1994-12-15. PMID:7947029. |
these findings suggest that both glomerular hypertrophy and mesangial matrix increase in non-sclerotic glomeruli in fsgs may lead to glomerular sclerosis. |
1994-12-15 |
2023-08-12 |
Not clear |
| Q L Cheng, X M Chen, S Z Sh. [Effects of Epimedium sagittatum on immunopathology and extracellular matrices in rats with chronic renal insufficiency]. Zhonghua nei ke za zhi. vol 33. issue 2. 1994-09-28. PMID:8070296. |
ep inhibited the hypertrophy of glomeruli in the rats. |
1994-09-28 |
2023-08-12 |
rat |
| N Marcussen, J R Nyengaard, S Christense. Compensatory growth of glomeruli is accomplished by an increased number of glomerular capillaries. Laboratory investigation; a journal of technical methods and pathology. vol 70. issue 6. 1994-07-28. PMID:8015291. |
in rats with lithium nephropathy, hypertrophy is found in glomeruli with normal tubular connection. |
1994-07-28 |
2023-08-12 |
rat |
| T Ohshima, S Inaba, M Arai, Y Sakai, K Kurose, S Ishihara, T Takahashi, R Takai, H Matukura, R Yoshid. [A case of oligomeganephronia--quantitative measurement of the glomerular surface area and the number of glomeruli with a color image analyzer]. Nihon Jinzo Gakkai shi. vol 36. issue 3. 1994-06-24. PMID:8196224. |
all the scanned glomeruli showed marked hypertrophy; the mean maximal surface area for the 5 glomeruli was 46 x 10(3) microns 2, which is approximately 4 times larger than that of normal children of the same age. |
1994-06-24 |
2023-08-12 |
Not clear |
| S H Park, J G Ch. Oligomeganephronia associated with 4p deletion type chromosomal anomaly. Pediatric pathology. vol 13. issue 6. 1994-03-21. PMID:8108293. |
oligomeganephronia is a rare congenital renal hypoplasia that is characterized histologically by a reduction in the number of reniculi with compensatory hypertrophy of the glomeruli and proximal renal tubules. |
1994-03-21 |
2023-08-12 |
Not clear |
| H Kubosawa, H Nakayama, T Sano, Y Kond. Morphological alterations of glomerulus induced by infusion of cationized ferritin. Acta pathologica japonica. vol 43. issue 9. 1993-12-13. PMID:8237364. |
on the other hand, in severely involved glomeruli, capillary loops were still obstructed even at 24 h by hypertrophic and proliferated endothelial cells as well as mesangial cells, instead of platelets and fibrin strands. |
1993-12-13 |
2023-08-12 |
rat |