| Reference |
Sentence |
Publish Date |
Extraction Date |
Species |
| Y Kawata, M Okada, T Murakami, K Mizuno, K Wada, T Kondo, S Kanek. Effects of zonisamide on K+ and Ca2+ evoked release of monoamine as well as K+ evoked intracellular Ca2+ mobilization in rat hippocampus. Epilepsy research vol 35 issue 3 1999 10413313 |
to clarify the effects of zonisamide (zns) on neurotransmission and intracellular ca2+ mobilization, both ca2+ and k+ evoked hippocampal releases of dopamine (da) and serotonin (5-ht) were determined by in vivo microdialysis, and k+ (25 and 50 mm) evoked elevation of intracellular ca2+ level was determined by fluorescence microscopy in vitro. |
1999-09-01 |
2022-01-10 |
Not clear |
| M Durand, O Berton, S Aguerre, L Edno, I Combourieu, P Morm\\xc3\\xa8de, F Chaoulof. Effects of repeated fluoxetine on anxiety-related behaviours, central serotonergic systems, and the corticotropic axis axis in SHR and WKY rats. Neuropharmacology vol 38 issue 6 1999 10465693 |
in both strains, the 10 mg/kg dose of fluoxetine decreased hypothalamus 5-ht and 5-hiaa levels, and reduced midbrain and/or hippocampus [3h]citalopram binding at 5-ht transporters, but did not affect [3h]8-hydroxy-2-(di-n-propylamino)tetralin binding at hippocampal 5-ht1a receptors. |
1999-08-25 |
2022-01-10 |
Not clear |
| M Durand, O Berton, S Aguerre, L Edno, I Combourieu, P Morm\\xc3\\xa8de, F Chaoulof. Effects of repeated fluoxetine on anxiety-related behaviours, central serotonergic systems, and the corticotropic axis axis in SHR and WKY rats. Neuropharmacology vol 38 issue 6 1999 10465693 |
however, the fluoxetine-elicited reduction in hippocampal 5-ht transporter binding was much more important in wky than in shr rats, this strain-dependent effect being associated in wky rats with a reduction in cortical [3h]ketanserin binding at 5-ht2a receptors. |
1999-08-25 |
2022-01-10 |
Not clear |
| G F Molodtsov. [Sexual and interhemispheric differences in the involvement of serotonin from the hippocampus and amygdaloid body in the processing of new and repeatedly presented information in rats]. Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova vol 49 issue 3 1999 10420552 |
in male rats, the hippocampal level of 5-ht in response to the novel stimulus increased in the left hemisphere, and the 5-hiaa hippocampal level increased bilaterally in response to irrelevant stimulus. |
1999-08-18 |
2022-01-10 |
Not clear |
| A M Magari\\xc3\\xb1os, A Deslandes, B S McEwe. Effects of antidepressants and benzodiazepine treatments on the dendritic structure of CA3 pyramidal neurons after chronic stress. European journal of pharmacology vol 371 issue 2-3 1999 10357248 |
these findings suggest that the synaptic availability of 5-ht is involved in the mechanism leading to stress-induced dendritic remodeling and supports the idea that the hippocampal inhibitory gabaergic tone may play a regulatory role. |
1999-08-13 |
2022-01-10 |
Not clear |
| C Leranth, R P Verte. Median raphe serotonergic innervation of medial septum/diagonal band of broca (MSDB) parvalbumin-containing neurons: possible involvement of the MSDB in the desynchronization of the hippocampal EEG. The Journal of comparative neurology vol 410 issue 4 1999 10398050 |
this could be a direct effect, because serotonin (5-ht) fibers terminate on a specific population of hippocampal interneurons. |
1999-08-03 |
2022-01-10 |
Not clear |
| C Leranth, R P Verte. Median raphe serotonergic innervation of medial septum/diagonal band of broca (MSDB) parvalbumin-containing neurons: possible involvement of the MSDB in the desynchronization of the hippocampal EEG. The Journal of comparative neurology vol 410 issue 4 1999 10398050 |
these observations indicate that 5-ht has a dual action on the activity of hippocampal principal cells: 1) an inhibition of the input sector by activation of hippocampal gaba neurons that terminate exclusively on apical dendrites of pyramidal cells, and 2) a disinhibition of the output sector of principal neurons. |
1999-08-03 |
2022-01-10 |
Not clear |
| C Gemma, L Imeri, M Manci. Hippocampal type 1 (movement-related) theta rhythm positively correlates with serotonergic activity. Archives italiennes de biologie vol 137 issue 2-3 1999 10349493 |
to investigate the relationship between the hippocampal [symbol: see text] activity (or rhythmical slow activity, rsa) and the hippocampal serotonergic activity during spontaneous behavior, simultaneous recordings of i) hippocampal eeg, ii) sleep-wake activity, and iii) hippocampal levels of the serotonin (5-ht) metabolite 5-hydroxyndolacetic acid (5-hiaa--measured by in vivo voltammetry and infrared telemetry) were performed. |
1999-07-23 |
2022-01-10 |
Not clear |
| C Gemma, L Imeri, M Manci. Hippocampal type 1 (movement-related) theta rhythm positively correlates with serotonergic activity. Archives italiennes de biologie vol 137 issue 2-3 1999 10349493 |
since in the experimental conditions used in the study, 5-hiaa levels are a reliable index of 5-ht release, the results support the hypothesis that hippocampal type 1 rsa is generated by a serotonergic mechanism. |
1999-07-23 |
2022-01-10 |
Not clear |
| C Gemma, L Imeri, M Manci. Hippocampal type 1 (movement-related) theta rhythm positively correlates with serotonergic activity. Archives italiennes de biologie vol 137 issue 2-3 1999 10349493 |
in contrast, hippocampal type 2 rsa recorded during desynchronized sleep is negatively correlated with 5-ht release, suggesting a different neurochemical mechanism for its production. |
1999-07-23 |
2022-01-10 |
Not clear |
| J M Brezun, A Daszut. Depletion in serotonin decreases neurogenesis in the dentate gyrus and the subventricular zone of adult rats. Neuroscience vol 89 issue 4 1999 10362289 |
prenatal depletion in 5-hydroxytryptamine delays the onset of neurogenesis in 5-hydroxytryptamine target regions and 5-hydroxytryptamine promotes the differentiation of cortical and hippocampal neurons. |
1999-07-22 |
2022-01-10 |
Not clear |
| J M Brezun, A Daszut. Depletion in serotonin decreases neurogenesis in the dentate gyrus and the subventricular zone of adult rats. Neuroscience vol 89 issue 4 1999 10362289 |
if further work confirms that new neurons can be produced in the adult human brain as is the case for a variety of species, it is particularly relevant to determine the influence of 5-hydroxytryptamine on neurogenesis in the hippocampal formation, a part of the brain largely implicated in learning and memory processes. |
1999-07-22 |
2022-01-10 |
Not clear |
| E Gur, E Dremencov, B Lerer, M E Newma. Venlafaxine: acute and chronic effects on 5-hydroxytryptamine levels in rat brain in vivo. European journal of pharmacology vol 372 issue 1 1999 10374710 |
injection resulted in dose-dependent increases in cortical and hippocampal 5-ht levels, as measured by in vivo microdialysis, over the range 5-20 mg/kg. |
1999-07-21 |
2022-01-10 |
Not clear |
| F Blomstrand, S Khatibi, H Muyderman, E Hansson, T Olsson, L R\\xc3\\xb6nnb\\xc3\\xa4c. 5-Hydroxytryptamine and glutamate modulate velocity and extent of intercellular calcium signalling in hippocampal astroglial cells in primary cultures. Neuroscience vol 88 issue 4 1999 10336133 |
5-hydroxytryptamine and glutamate modulate velocity and extent of intercellular calcium signalling in hippocampal astroglial cells in primary cultures. |
1999-07-15 |
2022-01-10 |
Not clear |
| E Balse, R Suhr, A Haaf, C Kelche, R Jackisch, J C Casse. The potentiation of amphetamine-induced hyperlocomotion by fimbria-fornix lesions in rats is abolished by intrahippocampal grafts rich in serotonergic neurons. Neuroscience letters vol 265 issue 2 1999 10327173 |
the effects of the lesions and grafts were assessed by measuring the accumulation of [3h]-choline or [3h]-5-hydroxytryptamine (5-ht) by hippocampal slices, and the electrically-evoked release of tritium. |
1999-06-29 |
2022-01-10 |
Not clear |
| M Okada, T Hirano, Y Kawata, T Murakami, K Wada, K Mizuno, T Kondo, S Kanek. Biphasic effects of zonisamide on serotonergic system in rat hippocampus. Epilepsy research vol 34 issue 2-3 1999 10210034 |
zns concentrations of 30-1000 microm did not affect hippocampal 5ht re uptake activity in vitro. |
1999-06-17 |
2022-01-10 |
Not clear |
| J F L\\xc3\\xb3pez, I Liberzon, D M V\\xc3\\xa1zquez, E A Young, S J Watso. Serotonin 1A receptor messenger RNA regulation in the hippocampus after acute stress. Biological psychiatry vol 45 issue 7 1999 10202584 |
when rats are subjected to chronic stress for 2 weeks, a significant decrease in hippocampal serotonin (5-ht)1a messenger rna (mrna) is observed. |
1999-06-14 |
2022-01-10 |
Not clear |
| R Jackisch, A Haaf, H Jeltsch, C Lazarus, C Kelche, J C Casse. Modulation of 5-hydroxytryptamine release in hippocampal slices of rats: effects of fimbria-fornix lesions on 5-HT1B-autoreceptor and alpha2-heteroreceptor function. Brain research bulletin vol 48 issue 1 1999 10210167 |
modulation of 5-hydroxytryptamine release in hippocampal slices of rats: effects of fimbria-fornix lesions on 5-ht1b-autoreceptor and alpha2-heteroreceptor function. |
1999-06-03 |
2022-01-10 |
Not clear |
| R Jackisch, A Haaf, H Jeltsch, C Lazarus, C Kelche, J C Casse. Modulation of 5-hydroxytryptamine release in hippocampal slices of rats: effects of fimbria-fornix lesions on 5-HT1B-autoreceptor and alpha2-heteroreceptor function. Brain research bulletin vol 48 issue 1 1999 10210167 |
hippocampal slices of sham-operated (sham) and fimbria-fornix-lesioned (les) rats (14 months after surgery) were preincubated with [3h]5-ht, superfused continuously, and stimulated electrically using two stimulation conditions: either (a) 360 pulses 3 hz, or (b) 20 pulses 100 hz (2 ms, 28 ma, 4 v/chamber). |
1999-06-03 |
2022-01-10 |
Not clear |
| R Jackisch, A Haaf, H Jeltsch, C Lazarus, C Kelche, J C Casse. Modulation of 5-hydroxytryptamine release in hippocampal slices of rats: effects of fimbria-fornix lesions on 5-HT1B-autoreceptor and alpha2-heteroreceptor function. Brain research bulletin vol 48 issue 1 1999 10210167 |
in les rats, hippocampal 5-ht content was reduced to about 45% of sham levels, whereas that of noradrenaline was increased by about 30% (high-performance liquid chromatography). |
1999-06-03 |
2022-01-10 |
Not clear |