| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Miguel Ángel López-Vázquez, Elisa López-Loeza, Naima Lajud Ávila, Blanca Erika Gutiérrez-Guzmán, J Jesús Hernández-Pérez, Yoana Estrada Reyes, María Esther Olvera-Corté. Septal serotonin depletion in rats facilitates working memory in the radial arm maze and increases hippocampal high-frequency theta activity. European journal of pharmacology. vol 734. 2015-01-28. PMID:24742376. |
we addressed whether serotonin depletion of the ms/dbb induces changes in the characteristics of hippocampal theta activity and whether the depletion is associated with learning in a working memory spatial task in the radial arm maze. |
2015-01-28 |
2023-08-13 |
rat |
| Rafael C Almada, Lucas Albrechet-Souza, Marcus L Brandã. Further evidence for involvement of the dorsal hippocampus serotonergic and γ-aminobutyric acid (GABA)ergic pathways in the expression of contextual fear conditioning in rats. Journal of psychopharmacology (Oxford, England). vol 27. issue 12. 2015-01-27. PMID:23535348. |
intra-dorsal hippocampus (dh) injections of 8-hydroxy-2-(di-n-propylamino) tetralin (8-oh-dpat), a serotonin-1a (5-hydroxytryptamine (5-ht)-1a) receptor agonist, were previously shown to inhibit the expression of contextual fear when administered six hours after conditioning. |
2015-01-27 |
2023-08-12 |
rat |
| Fabiana K Ludka, Leandra Celso Constantino, Gislaine Kuminek, Luisa Bandeira Binder, Andréa D E Zomkowski, Maurício P Cunha, Tharine Dal-Cim, Ana Lúcia S Rodrigues, Carla I Tasc. Atorvastatin evokes a serotonergic system-dependent antidepressant-like effect in mice. Pharmacology, biochemistry, and behavior. vol 122. 2015-01-26. PMID:24769309. |
), a serotonin selective reuptake inhibitor (ssri) was able to exert an antidepressant-like effect, but any of them changed 5-ht content in the hippocampus or frontal cortex. |
2015-01-26 |
2023-08-13 |
mouse |
| Balwant P Salunke, Sudhir N Umathe, Jagatpalsingh G Chava. Experimental evidence for involvement of nitric oxide in low frequency magnetic field induced obsessive compulsive disorder-like behavior. Pharmacology, biochemistry, and behavior. vol 122. 2015-01-26. PMID:24780504. |
the neurohumoral studies revealed that exposure to elf mf increased no levels in cortex, hippocampus and hypothalamus, and levels of dopamine and serotonin remain unaffected. |
2015-01-26 |
2023-08-13 |
mouse |
| Bruno P Guiard, Mostafa El Mansari, Dennis L Murphy, Pierre Blie. Altered response to the selective serotonin reuptake inhibitor escitalopram in mice heterozygous for the serotonin transporter: an electrophysiological and neurochemical study. The international journal of neuropsychopharmacology. vol 15. issue 3. 2015-01-22. PMID:21439106. |
in the hippocampus, microdialysis revealed that sustained administration of escitalopram produced a greater increase in extracellular 5-ht ([5-ht]ext) outflow in sert+/- than in the wild-types with or without a washout of the ssri. |
2015-01-22 |
2023-08-12 |
mouse |
| Bruno P Guiard, Mostafa El Mansari, Dennis L Murphy, Pierre Blie. Altered response to the selective serotonin reuptake inhibitor escitalopram in mice heterozygous for the serotonin transporter: an electrophysiological and neurochemical study. The international journal of neuropsychopharmacology. vol 15. issue 3. 2015-01-22. PMID:21439106. |
nevertheless, the ability of microiontophoretically applied 5-ht to inhibit the firing rate of ca3 pyramidal neurons was not different between sert+/+ and sert+/- mice given escitalopram for 21 d. the data indicate that the poor response to ssris of depressive patients with short allele(s) of sert is not attributable to a lesser increase in 5-ht transmission in the hippocampus. |
2015-01-22 |
2023-08-12 |
mouse |
| Yoon Hee Chung, Young Joo Lee, Ho Sung Lee, Su Jin Chung, Cheol Hee Lim, Keon Woong Oh, Uy Dong Sohn, Eon Sub Park, Ji Hoon Jeon. Extremely low frequency magnetic field modulates the level of neurotransmitters. The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology. vol 19. issue 1. 2015-01-21. PMID:25605992. |
significant increases in the levels of serotonin and 5-hydroxyindoleacetic acid were also observed in the striatum, thalamus or hippocampus. |
2015-01-21 |
2023-08-13 |
rat |
| Maryam S Vasefi, Kai Yang, Jerry Li, Jeff S Kruk, John J Heikkila, Michael F Jackson, John F MacDonald, Michael A Beazel. Acute 5-HT7 receptor activation increases NMDA-evoked currents and differentially alters NMDA receptor subunit phosphorylation and trafficking in hippocampal neurons. Molecular brain. vol 6. 2015-01-21. PMID:23672716. |
serotonin (5-ht) type 7 receptors are expressed throughout the brain including the thalamus and hippocampus. |
2015-01-21 |
2023-08-12 |
Not clear |
| Li Wen, Yahong Jin, Lei Li, Shuangyu Sun, Shixiang Cheng, Sai Zhang, Yong Zhang, Per Svenningsso. Exercise prevents raphe nucleus mitochondrial overactivity in a rat depression model. Physiology & behavior. vol 132. 2015-01-21. PMID:24813829. |
serotonin levels were measured in the raphe nuclei and hippocampus. |
2015-01-21 |
2023-08-13 |
rat |
| Li Wen, Yahong Jin, Lei Li, Shuangyu Sun, Shixiang Cheng, Sai Zhang, Yong Zhang, Per Svenningsso. Exercise prevents raphe nucleus mitochondrial overactivity in a rat depression model. Physiology & behavior. vol 132. 2015-01-21. PMID:24813829. |
hippocampal serotonin was lower in group d than in the other groups (p<0.01); levels in the raphe nuclei were elevated in group de compared with the remaining groups (p<0.001). |
2015-01-21 |
2023-08-13 |
rat |
| S Graziani, D Christin, S Daulon, P Breton, N Perrier, L Tayss. Effects of repeated low-dose exposure of the nerve agent VX on monoamine levels in different brain structures in mice. Neurochemical research. vol 39. issue 5. 2015-01-16. PMID:24676701. |
during the toxic challenge, an increase of the serotonin metabolism was noted in hippocampus (hpc), hypothalamus/thalamus, pons medulla and cerebellum (cer). |
2015-01-16 |
2023-08-12 |
mouse |
| Zhang Tianzhu, Yang Shihai, Du Jua. Antidepressant-like effects of cordycepin in a mice model of chronic unpredictable mild stress. Evidence-based complementary and alternative medicine : eCAM. vol 2014. 2015-01-14. PMID:25587342. |
then the serotonin (5-ht) and noradrenaline (ne) concentrations in hippocampal were evaluated by hplc; tumor necrosis factor-α (tnf-α) and interleukin-6 (il-6) in hippocampal were evaluated, and the proteins of tnf-α, il-6, nf-κbp65 5-ht2a receptor (5-ht2ar), and brain-derived neurotrophic factor (bdnf) in hippocampal were evaluated by western blot. |
2015-01-14 |
2023-08-13 |
mouse |
| Zhang Tianzhu, Yang Shihai, Du Jua. Antidepressant-like effects of cordycepin in a mice model of chronic unpredictable mild stress. Evidence-based complementary and alternative medicine : eCAM. vol 2014. 2015-01-14. PMID:25587342. |
our results indicated that 6 weeks of cums exposure induced significant depression-like behavior, with low 5-ht and ne levels, high tnf-α and il-6 in brain and high hippocampal tnf-α, il-6, p-nf-κbp65, and 5-ht2ar levels, and low bdnf expression levels. |
2015-01-14 |
2023-08-13 |
mouse |
| Cédric B P Martin, Martin Gassmann, Caroline Chevarin, Michel Hamon, Uwe Rudolph, Bernhard Bettler, Laurence Lanfumey, Raymond Mongea. Effect of genetic and pharmacological blockade of GABA receptors on the 5-HT2C receptor function during stress. Journal of neurochemistry. vol 131. issue 5. 2015-01-14. PMID:25113583. |
to address this question, we assessed the inhibition of 5-ht turnover by a 5-ht2c receptor agonist (ro 60-0175) at the hippocampal level and under conditions of stress, after pharmacological or genetic inactivation of either gaba-a or gaba-b receptors in mice. |
2015-01-14 |
2023-08-13 |
mouse |
| Cédric B P Martin, Martin Gassmann, Caroline Chevarin, Michel Hamon, Uwe Rudolph, Bernhard Bettler, Laurence Lanfumey, Raymond Mongea. Effect of genetic and pharmacological blockade of GABA receptors on the 5-HT2C receptor function during stress. Journal of neurochemistry. vol 131. issue 5. 2015-01-14. PMID:25113583. |
it can be inferred that non-α3 subunit-containing gaba-a receptors, but not gaba-b receptors, mediate the 5-ht2c -induced inhibition of stress-induced increase in hippocampal 5-ht turnover in mice. |
2015-01-14 |
2023-08-13 |
mouse |
| Jeremy D Coplan, Sasha L Fulton, Wade Reiner, Andrea Jackowski, Venkatesh Panthangi, Tarique D Perera, Jack M Gorman, Yung-Yu Huang, Cheuk Y Tang, Patrick R Hof, Arie Kaffman, Andrew J Dwork, Sanjay J Mathew, Joan Kaufman, J John Man. Elevated cerebrospinal fluid 5-hydroxyindoleacetic acid in macaques following early life stress and inverse association with hippocampal volume: preliminary implications for serotonin-related function in mood and anxiety disorders. Frontiers in behavioral neuroscience. vol 8. 2015-01-08. PMID:25566007. |
a putatively decreased serotonin neurotransmission would be reflected by reductions in hippocampal volume and white matter (wm) fractional anisotropy (fa). |
2015-01-08 |
2023-08-13 |
monkey |
| Ronise M Santiago, Janaína Barbiero, Bruno J Martynhak, Suelen L Boschen, Luisa M da Silva, Maria F P Werner, Claudio Da Cunha, Roberto Andreatini, Marcelo M S Lima, Maria A B F Vita. Antidepressant-like effect of celecoxib piroxicam in rat models of depression. Journal of neural transmission (Vienna, Austria : 1996). vol 121. issue 6. 2015-01-07. PMID:24463888. |
piroxicam increased serotonin and norepinephrine levels in the hippocampus. |
2015-01-07 |
2023-08-12 |
rat |
| Ariana Ern Schmitz, Paulo Alexandre de Oliveira, Luiz F de Souza, Danilo Grünig Humberto da Silva, Samara Danielski, Danúbia Bonfanti Santos, Eduardo Alves de Almeida, Rui Daniel Prediger, Andrew Fisher, Marcelo Farina, Alcir Luiz Dafr. Interaction of curcumin with manganese may compromise metal and neurotransmitter homeostasis in the hippocampus of young mice. Biological trace element research. vol 158. issue 3. 2014-12-19. PMID:24723215. |
moreover, the association of mn plus curcumin significantly increased the levels of mn and iron, and decreased the levels of dopamine and serotonin in the hippocampus. |
2014-12-19 |
2023-08-13 |
mouse |
| Fei Huang, Jia Li, Hai-Lian Shi, Ting-ting Wang, Wahaf Muhtar, Min Du, Bei-bei Zhang, Hui Wu, Li Yang, Zhi-bi Hu, Xiao-jun W. Simultaneous quantification of seven hippocampal neurotransmitters in depression mice by LC-MS/MS. Journal of neuroscience methods. vol 229. 2014-12-16. PMID:24735530. |
there is no method available to simultaneously detect gaba, glu, epi, ne, da, 5-ht and 5-hiaa in mouse hippocampus. |
2014-12-16 |
2023-08-13 |
mouse |
| Michelle G Baladi, Amy H Newman, Shannon M Nielsen, Glen R Hanson, Annette E Fleckenstei. Dopamine D(3) receptors contribute to methamphetamine-induced alterations in dopaminergic neuronal function: role of hyperthermia. European journal of pharmacology. vol 732. 2014-12-09. PMID:24685638. |
results indicate that the dopamine d3 receptor selective antagonist, pg01037, attenuated methamphetamine-induced decreases in striatal dat, but not hippocampal serotonin (5ht) transporter (sert), function, as assessed 7 days after treatment. |
2014-12-09 |
2023-08-12 |
rat |