| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hideki Miura, Hong Qiao, Tatsuro Oht. Influence of aging and social isolation on changes in brain monoamine turnover and biosynthesis of rats elicited by novelty stress. Synapse (New York, N.Y.). vol 46. issue 2. 2002-11-19. PMID:12211090. |
changes in brain monoamines and their metabolites such as dopamine (da), serotonin (5-ht), dihydroxyphenylacetic acid (dopac), homovanilic acid (hva), and 5-hydroxyindoleacetic acid (5-hiaa) were measured in six regions: the prefrontal cortex, nucleus accumbens, hippocampus, amygdala, midbrain, and raphe nuclei. |
2002-11-19 |
2023-08-12 |
human |
| M Kamali, M A Oquendo, J J Man. Understanding the neurobiology of suicidal behavior. Depression and anxiety. vol 14. issue 3. 2002-04-18. PMID:11747126. |
the main regions of interest in the cns have been the dorsal and median raphe nuclei in the midbrain that host the main serotonergic cell bodies and the prefrontal cortex, particularly the ventral pfc, innervated by the serotonergic system. |
2002-04-18 |
2023-08-12 |
Not clear |
| N Brunel, X J Wan. Effects of neuromodulation in a cortical network model of object working memory dominated by recurrent inhibition. Journal of computational neuroscience. vol 11. issue 1. 2001-12-04. PMID:11524578. |
these mechanisms could be implemented in the prefrontal cortex by dopaminergic projections from the midbrain. |
2001-12-04 |
2023-08-12 |
Not clear |
| M E Hamilton, F K Weddige, A S Freema. Effects of forebrain microinjection of cholecystokinin on dopamine cell firing rate. Peptides. vol 22. issue 7. 2001-11-01. PMID:11445235. |
in anesthetized rats, midbrain dopamine (da) neuronal firing rate was differentially sensitive to focal brain microinjection of cholecystokinin peptides (cck-4 and cck-8) and n-methyl-d-aspartate (nmda) into nucleus accumbens, amygdala and prefrontal cortex. |
2001-11-01 |
2023-08-12 |
rat |
| E A Zahalka, D H Ellis, E S Goldey, M E Stanton, C La. Perinatal exposure to polychlorinated biphenyls Aroclor 1016 or 1254 did not alter brain catecholamines nor delayed alternation performance in Long-Evans rats. Brain research bulletin. vol 55. issue 4. 2001-10-18. PMID:11543949. |
at various age intervals, rats were sacrificed and six brain regions (prefrontal cortex, striatum, hippocampus, diencephalon, cerebellum, midbrain + brain stem) were removed and analyzed for dopamine (da) and norepinephrine (ne) levels by high-performance liquid chromatography. |
2001-10-18 |
2023-08-12 |
rat |
| M E Jackson, A S Frost, B Moghadda. Stimulation of prefrontal cortex at physiologically relevant frequencies inhibits dopamine release in the nucleus accumbens. Journal of neurochemistry. vol 78. issue 4. 2001-09-20. PMID:11520912. |
the evidence for this influence primarily arises from findings in the rat that chemical or high-intensity and high-frequency (60-200 hz) electrical stimulations of pfc increase burst activity of midbrain dopamine neurons, and augment terminal release of dopamine in the nucleus accumbens. |
2001-09-20 |
2023-08-12 |
rat |
| K Sidiropoulou, S Chao, W Lu, M E Wol. Amphetamine administration does not alter protein levels of the GLT-1 and EAAC1 glutamate transporter subtypes in rat midbrain, nucleus accumbens, striatum, or prefrontal cortex. Brain research. Molecular brain research. vol 90. issue 2. 2001-09-13. PMID:11406296. |
amphetamine administration does not alter protein levels of the glt-1 and eaac1 glutamate transporter subtypes in rat midbrain, nucleus accumbens, striatum, or prefrontal cortex. |
2001-09-13 |
2023-08-12 |
rat |
| A Scandroglio, E Monferini, F Borsin. Ex vivo binding of flibanserin to serotonin 5-HT1A and 5-HT2A receptors. Pharmacological research. vol 43. issue 2. 2001-05-17. PMID:11243720. |
this interaction was evaluated in the prefrontal cortex, hippocampus and midbrain by using [3h]8-oh-dpat and [3h]ketanserin to label 5-ht1a and 5-ht2a receptors, respectively. |
2001-05-17 |
2023-08-12 |
Not clear |
| D P Hanes, R H Wurt. Interaction of the frontal eye field and superior colliculus for saccade generation. Journal of neurophysiology. vol 85. issue 2. 2001-04-19. PMID:11160514. |
both the frontal eye field (fef) in the prefrontal cortex and the superior colliculus (sc) on the roof of the midbrain participate in the generation of rapid or saccadic eye movements and both have projections to the premotor circuits of the brain stem where saccades are ultimately generated. |
2001-04-19 |
2023-08-12 |
monkey |
| L S Kegeles, A Abi-Dargham, Y Zea-Ponce, J Rodenhiser-Hill, J J Mann, R L Van Heertum, T B Cooper, A Carlsson, M Laruell. Modulation of amphetamine-induced striatal dopamine release by ketamine in humans: implications for schizophrenia. Biological psychiatry. vol 48. issue 7. 2000-12-05. PMID:11032974. |
the activity of midbrain dopaminergic neurons is regulated, in part, by glutamatergic projections from the pfc acting via glutamatergic n-methyl-d-aspartate (nmda) receptors. |
2000-12-05 |
2023-08-12 |
Not clear |
| I Liberzon, S F Taylor, L M Fig, L R Decker, R A Koeppe, S Minoshim. Limbic activation and psychophysiologic responses to aversive visual stimuli. Interaction with cognitive task. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 23. issue 5. 2000-11-21. PMID:11027916. |
aversive pictures, relative to neutral pictures, increased cerebral activity in bilateral amygdala, thalamic/hypothalamic area, midbrain, and left lateral prefrontal cortex, along with greater skin conductance responses (scr). |
2000-11-21 |
2023-08-12 |
human |
| b' M D Fatigati, R M Anderson, P Rompr\\xc3\\xa. Effects of prefrontal cortex microinjection of neurotensin-(8-13) on midbrain dopamine and non-dopamine cell firing. Brain research. vol 876. issue 1-2. 2000-10-18. PMID:10973609.' |
effects of prefrontal cortex microinjection of neurotensin-(8-13) on midbrain dopamine and non-dopamine cell firing. |
2000-10-18 |
2023-08-12 |
rat |
| b' M D Fatigati, R M Anderson, P Rompr\\xc3\\xa. Effects of prefrontal cortex microinjection of neurotensin-(8-13) on midbrain dopamine and non-dopamine cell firing. Brain research. vol 876. issue 1-2. 2000-10-18. PMID:10973609.' |
effects of prefrontal cortex microinjections of 0.3 and 3 nmol/0.5 microl of neurotensin-(8-13) on the firing rate of midbrain dopamine and non-dopamine cells were studied in urethane-anesthetized rats. |
2000-10-18 |
2023-08-12 |
rat |
| b' M D Fatigati, R M Anderson, P Rompr\\xc3\\xa. Effects of prefrontal cortex microinjection of neurotensin-(8-13) on midbrain dopamine and non-dopamine cell firing. Brain research. vol 876. issue 1-2. 2000-10-18. PMID:10973609.' |
these results show that prefrontal cortex neurotensin can modulate both dopamine and non-dopamine neurotransmission in the ventral midbrain. |
2000-10-18 |
2023-08-12 |
rat |
| W Lu, L M Monteggia, M E Wol. Withdrawal from repeated amphetamine administration reduces NMDAR1 expression in the rat substantia nigra, nucleus accumbens and medial prefrontal cortex. The European journal of neuroscience. vol 11. issue 9. 1999-11-24. PMID:10510180. |
we quantified nmdar1 mrna (using in situ hybridization with 35s-labelled oligonucleotide probes) and immunolabelling (using immunocytochemistry with 35s-labelled secondary antibodies) in rat ventral midbrain, nucleus accumbens and prefrontal cortex after 3 or 14 days of withdrawal from five daily injections of saline or amphetamine sulphate (5 mg/kg/day). |
1999-11-24 |
2023-08-12 |
rat |
| S K Michelhaugh, G Pimputkar, M E Gneg. Alterations in calmodulin mRNA expression and calmodulin content in rat brain after repeated, intermittent amphetamine. Brain research. Molecular brain research. vol 62. issue 1. 1999-06-10. PMID:9795121. |
cam protein and mrna were measured in dorsal striatum, limbic forebrain, prefrontal cortex, ventral mesencephalon and piriform cortex. |
1999-06-10 |
2023-08-12 |
rat |
| D A Loeffler, P A LeWitt, P L Juneau, D M Camp, L A Arnold, K Hylan. Time-dependent effects of levodopa on regional brain dopamine metabolism and lipid peroxidation. Brain research bulletin. vol 47. issue 6. 1999-05-06. PMID:10078623. |
at 1, 4, 8, and 12 h after levodopa administration (100 mg/kg), dopamine, dihydroxyphenylacetic acid, and homovanillic acid were measured in striatum and ventral midbrain, regions containing marked dopaminergic innervation, and in prefrontal cortex and cerebellum, which possess little dopaminergic innervation. |
1999-05-06 |
2023-08-12 |
rat |
| A Bortolozzi, R O Duffard, M Rubio, N Sturtz, A M Evangelista de Duffar. Regionally specific changes in central brain monoamine levels by 2,4-dichlorophenoxyacetic acid in acute treated rats. Neurotoxicology. vol 19. issue 6. 1999-03-16. PMID:9863773. |
the prefrontal cortex (pfc), striatum, nucleus accumbens (na), midbrain, ventral tegmental area (vta), substantia nigra (sn) and cerebellum were assayed. |
1999-03-16 |
2023-08-12 |
rat |
| A Bortolozzi, R O Duffard, M Rubio, N Sturtz, A M Evangelista de Duffar. Regionally specific changes in central brain monoamine levels by 2,4-dichlorophenoxyacetic acid in acute treated rats. Neurotoxicology. vol 19. issue 6. 1999-03-16. PMID:9863773. |
we are demonstrating a correlation between rat behavior altered by the herbicide's treatment and the contents of 5-ht and da in brain areas, such as pfc, vta, sn, striatum, na, midbrain and cerebellum. |
1999-03-16 |
2023-08-12 |
rat |
| C A Stockmeier, L A Shapiro, G E Dilley, T N Kolli, L Friedman, G Rajkowsk. Increase in serotonin-1A autoreceptors in the midbrain of suicide victims with major depression-postmortem evidence for decreased serotonin activity. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 18. issue 18. 1998-10-02. PMID:9736659. |
serotonin-1a receptors are located on serotonin cell bodies in the midbrain dorsal raphe (dr) nucleus, and the activation of these receptors inhibits the firing of serotonin neurons and diminishes the release of this neurotransmitter in the prefrontal cortex. |
1998-10-02 |
2023-08-12 |
human |