| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| William Gordon Frankle, Mark Laruelle, Suzanne N Habe. Prefrontal cortical projections to the midbrain in primates: evidence for a sparse connection. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 31. issue 8. 2006-08-31. PMID:16395309. |
the results show a very limited projection from the pfc to the midbrain da neurons in primates, terminating both within the sn proper as well as in the vta. |
2006-08-31 |
2023-08-12 |
monkey |
| George L Chadderdon, Olaf Sporn. A large-scale neurocomputational model of task-oriented behavior selection and working memory in prefrontal cortex. Journal of cognitive neuroscience. vol 18. issue 2. 2006-05-25. PMID:16494684. |
the model consists of multiple brain regions containing neuronal populations with realistic physiological and anatomical properties, including extrastriate visual cortical regions, the inferotemporal cortex, the pfc, the striatum, and midbrain dopamine (da) neurons. |
2006-05-25 |
2023-08-12 |
Not clear |
| Jean-Claude Dreher, Philip Kohn, Karen Faith Berma. Neural coding of distinct statistical properties of reward information in humans. Cerebral cortex (New York, N.Y. : 1991). vol 16. issue 4. 2006-05-10. PMID:16033924. |
moreover, distinct activity dynamics were observed in post-synaptic midbrain projection sites: the prefrontal cortex responded to the transient error prediction signal while the ventral striatum covaried with the sustained reward uncertainty signal. |
2006-05-10 |
2023-08-12 |
Not clear |
| Björn H Schott, Constanze I Seidenbecher, Daniela B Fenker, Corinna J Lauer, Nico Bunzeck, Hans-Gert Bernstein, Wolfgang Tischmeyer, Eckart D Gundelfinger, Hans-Jochen Heinze, Emrah Düze. The dopaminergic midbrain participates in human episodic memory formation: evidence from genetic imaging. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 26. issue 5. 2006-04-27. PMID:16452664. |
the catechol-o-methyl transferase (comt) val108/158met polymorphism, which is known to modulate enzyme activity, affected encoding-related activity in the right prefrontal cortex (pfc) and in occipital brain regions but not in the midbrain. |
2006-04-27 |
2023-08-12 |
human |
| Björn H Schott, Constanze I Seidenbecher, Daniela B Fenker, Corinna J Lauer, Nico Bunzeck, Hans-Gert Bernstein, Wolfgang Tischmeyer, Eckart D Gundelfinger, Hans-Jochen Heinze, Emrah Düze. The dopaminergic midbrain participates in human episodic memory formation: evidence from genetic imaging. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 26. issue 5. 2006-04-27. PMID:16452664. |
our finding that genetic variations in the dopamine clearance pathways affect encoding-related activation patterns in midbrain and pfc provides strong support for a role of dopaminergic neuromodulation in human episodic memory formation. |
2006-04-27 |
2023-08-12 |
human |
| G F Molodtsov. Metabolism and receptor binding of serotonin in brain structures during performance of a conditioned passive avoidance response. Neuroscience and behavioral physiology. vol 35. issue 7. 2006-03-02. PMID:16433063. |
the levels of serotonin and its metabolite 5-hydroxyindoleacetic acid, monoamine oxidase activity, and the specific binding of the radioligand [3h]serotonin were measured in the prefrontal cortex, striatum, amygdaloid complex, hippocampus, and periacqueductal gray matter of the midbrain in rats at different time points after training to a conditioned passive avoidance reaction. |
2006-03-02 |
2023-08-12 |
rat |
| G F Molodtsov. Changes in serotonin metabolism in the rat brain on presentation of a habituated stimulus. Neuroscience and behavioral physiology. vol 35. issue 6. 2006-01-05. PMID:16342611. |
these experiments showed that presentation of the habituated stimulus was accompanied by increases in serotonin metabolism and the active transport of its metabolite in the amygdaloid complex, striatum, and midbrain, with no significant changes in the hippocampus or prefrontal cortex. |
2006-01-05 |
2023-08-12 |
rat |
| Andreas Meyer-Lindenberg, Philip D Kohn, Bhaskar Kolachana, Shane Kippenhan, Aideen McInerney-Leo, Robert Nussbaum, Daniel R Weinberger, Karen Faith Berma. Midbrain dopamine and prefrontal function in humans: interaction and modulation by COMT genotype. Nature neuroscience. vol 8. issue 5. 2005-07-08. PMID:15821730. |
a common v(108/158)m substitution in the gene for catecholamine-o-methyltransferase (comt), an important enzyme regulating prefrontal dopamine turnover, predicted reduced dopamine synthesis in midbrain and qualitatively affected the interaction with prefrontal cortex. |
2005-07-08 |
2023-08-12 |
Not clear |
| Peter J Morgane, Janina R Galler, David J Mokle. A review of systems and networks of the limbic forebrain/limbic midbrain. Progress in neurobiology. vol 75. issue 2. 2005-05-26. PMID:15784304. |
major interacting structures of the limbic system include the prefrontal cortex, cingulate cortex, amygdaloid nuclear complex, limbic thalamus, hippocampal formation, nucleus accumbens (limbic striatum), anterior hypothalamus, ventral tegmental area and midbrain raphe nuclei; the latter comprising largely serotonergic components of the limbic midbrain system projecting to the forebrain. |
2005-05-26 |
2023-08-12 |
rat |
| Michael Bannon, Gregory Kapatos, Dawn Albertso. Gene expression profiling in the brains of human cocaine abusers. Addiction biology. vol 10. issue 1. 2005-05-19. PMID:15849025. |
finally, the effects of cocaine abuse on the profile of gene expression in some other brain regions critical for addiction (the prefrontal cortex and ventral midbrain) are briefly reviewed. |
2005-05-19 |
2023-08-12 |
human |
| Marcelo Febo, Annabell C Segarra, Govind Nair, Karl Schmidt, Timothy Q Duong, Craig F Ferri. The neural consequences of repeated cocaine exposure revealed by functional MRI in awake rats. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 30. issue 5. 2005-05-12. PMID:15637636. |
acute cocaine produced robust positive bold responses across well-known monoamine-enriched brain regions, such as the prefrontal cortex, nucleus accumbens, dorsal striatum, sensory cortex, hippocampus, thalamus, and midbrain areas. |
2005-05-12 |
2023-08-12 |
rat |
| Eleni T Tzavara, Frank P Bymaster, Richard J Davis, Mark R Wade, Kenneth W Perry, Jurgen Wess, David L McKinzie, Chris Felder, George G Nomiko. M4 muscarinic receptors regulate the dynamics of cholinergic and dopaminergic neurotransmission: relevance to the pathophysiology and treatment of related CNS pathologies. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 18. issue 12. 2005-04-05. PMID:15231726. |
dopaminergic neurons projecting from the midbrain to forebrain regions, such as the nucleus accumbens and the prefrontal cortex, regulate motor and cognitive functions and coordinate the patterned response of the organism to sensory, affective, and rewarding stimuli. |
2005-04-05 |
2023-08-12 |
mouse |
| G F Molodtsov. [Change in serotonin metabolism in the rat brain in response to the repeated stimulus presentation]. Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova. vol 90. issue 1. 2004-08-09. PMID:15143488. |
habituation to the stimulus was accompanied by an increase of 5-ht metabolism and active transport of 5-hiaa in the amygdala, striatum and midbrain, while these changes were not found in the prefrontal cortex and hippocampus. |
2004-08-09 |
2023-08-12 |
rat |
| Cynthia Shannon Weickert, Richard E Straub, Benjamin W McClintock, Mitsuyuki Matsumoto, Ryota Hashimoto, Thomas M Hyde, Mary M Herman, Daniel R Weinberger, Joel E Kleinma. Human dysbindin (DTNBP1) gene expression in normal brain and in schizophrenic prefrontal cortex and midbrain. Archives of general psychiatry. vol 61. issue 6. 2004-06-24. PMID:15184234. |
human dysbindin (dtnbp1) gene expression in normal brain and in schizophrenic prefrontal cortex and midbrain. |
2004-06-24 |
2023-08-12 |
human |
| M Matsumoto, C Shannon Weickert, M Akil, B K Lipska, T M Hyde, M M Herman, J E Kleinman, D R Weinberge. Catechol O-methyltransferase mRNA expression in human and rat brain: evidence for a role in cortical neuronal function. Neuroscience. vol 116. issue 1. 2003-06-24. PMID:12535946. |
in the present study, in situ hybridization histochemistry was employed to determine the mrna expression profile of comt in the human prefrontal cortex, striatum and midbrain and in the rat forebrain. |
2003-06-24 |
2023-08-12 |
human |
| H L Alderson, L F H Faulconbridge, L P Gregory, M P Latimer, P Win. Behavioural sensitisation to repeated d-amphetamine: effects of excitotoxic lesions of the pedunculopontine tegmental nucleus. Neuroscience. vol 118. issue 2. 2003-06-16. PMID:12699767. |
the pptg has direct and indirect connections with the nucleus accumbens and prefrontal cortex, and also influences midbrain dopamine activity through direct projections to substantia nigra and ventral tegmental area. |
2003-06-16 |
2023-08-12 |
rat |
| John Beard, Keith M Erikson, Byron C Jone. Neonatal iron deficiency results in irreversible changes in dopamine function in rats. The Journal of nutrition. vol 133. issue 4. 2003-04-30. PMID:12672939. |
iron repletion at pnd 21-49 normalized d(1)r, d(2)r, and dat levels in the nucleus accumbens, pfc and ventral midbrain but not in the striatum. |
2003-04-30 |
2023-08-12 |
human |
| Analía Bortolozzi, Ricardo Duffard, Ana María Evangelista de Duffar. Asymmetrical development of the monoamine systems in 2,4-dichlorophenoxyacetic acid treated rats. Neurotoxicology. vol 24. issue 1. 2003-03-21. PMID:12564390. |
the decreased dopamine (da), 3,4-dihydroxyphenylacetic acid (dopac) and homovallinic acid (hva) contents in cerebellum, midbrain, ventral tegmental area (vta) and prefrontal cortex (pfc) showed an alteration in the mesocorticolimbic system. |
2003-03-21 |
2023-08-12 |
rat |
| Analía Bortolozzi, Ricardo Duffard, Ana María Evangelista de Duffar. Asymmetrical development of the monoamine systems in 2,4-dichlorophenoxyacetic acid treated rats. Neurotoxicology. vol 24. issue 1. 2003-03-21. PMID:12564390. |
the contents of serotonin (5-hydroxytryptamine, 5-ht) were significantly increased in both sexes in pfc, striatum (st), midbrain, sn and cerebellum. |
2003-03-21 |
2023-08-12 |
rat |
| John L Beard, Keith M Erikson, Byron C Jone. Neurobehavioral analysis of developmental iron deficiency in rats. Behavioural brain research. vol 134. issue 1-2. 2002-11-19. PMID:12191838. |
iron deficient rats also showed significant decrements in brain iron content in the corpus striatum, prefrontal cortex, and midbrain and decreases in dopamine receptors and the transporter in the same areas. |
2002-11-19 |
2023-08-12 |
rat |