| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Bernardo Lopez-Torres, Irma Ares, Marta Martínez, Jorge-Enrique Maximiliano, María-Rosa Martínez-Larrañaga, Arturo Anadón, María-Aránzazu Martíne. Neurotoxicity induced by the pyrethroid lambda-cyhalothrin: Alterations in monoaminergic systems and dopaminergic and serotoninergic pathways in the rat brain. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2022-09-20. PMID:36126889. |
the effects of type ii pyrethroid lambda-cyhalothrin on dopamine (da) and serotonin (5-ht) synthesis in rat brain regions (striatum, hippocampus, prefrontal cortex, hypothalamus and midbrain) were studied. |
2022-09-20 |
2023-08-14 |
rat |
| Christopher J O'Connell, Evan L Reeder, Sean M Collins, Kainat Lungani, Sophia V Norman, Matthew J Robso. Mild traumatic brain injury elicits time- and region-specific reductions in serotonin transporter protein expression and uptake capacity. Neuroreport. vol 33. issue 14. 2022-09-05. PMID:36062511. |
concomitant reductions in midbrain sert-dependent radiolabeled 5-ht uptake were observed 3 dpi (≈24%). |
2022-09-05 |
2023-08-14 |
Not clear |
| Krishnan Sriram, Gary X Lin, Amy M Jefferson, Walter McKinney, Mark C Jackson, Jared L Cumpston, James B Cumpston, Howard D Leonard, Michael L Kashon, Jeffrey S Feda. Biological effects of inhaled crude oil vapor VI. Altered biogenic amine neurotransmitters and neural protein expression. Toxicology and applied pharmacology. 2022-06-24. PMID:35750205. |
sub-chronic cov exposure caused significant reductions in ne, epi and da in the dopaminergic brain regions, striatum (str) and midbrain (mb), and a large increase in 5-ht in the str. |
2022-06-24 |
2023-08-14 |
rat |
| Xing Cai, Hailan Liu, Bing Feng, Meng Yu, Yang He, Hesong Liu, Chen Liang, Yongjie Yang, Longlong Tu, Nan Zhang, Lina Wang, Na Yin, Junying Han, Zili Yan, Chunmei Wang, Pingwen Xu, Qi Wu, Qingchun Tong, Yanlin He, Yong X. Publisher Correction: A D2 to D1 shift in dopaminergic inputs to midbrain 5-HT neurons causes anorexia in mice. Nature neuroscience. 2022-06-21. PMID:35729403. |
publisher correction: a d2 to d1 shift in dopaminergic inputs to midbrain 5-ht neurons causes anorexia in mice. |
2022-06-21 |
2023-08-14 |
mouse |
| Khurshid Jalal, Faisal Khan, Shazia Nawaz, Rushda Afroz, Kanwal Khan, Sadia Basharat Ali, Liangliang Hao, Saeed Ahmad Khan, Mohsin Kazi, Reaz Uddin, Darakhshan Jabeen Halee. Anxiolytic, anti-nociceptive and body weight reducing effects of L-lysine in rats: Relationship with brain serotonin an In-Vivo and In-Silico study. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 152. 2022-06-13. PMID:35696944. |
5-hydroxytryptamine (5-ht, serotonin) metabolism, and tryptophan (trp) levels in the midbrain (mb), hippocampus (hp), and prefrontal cortex (pfc) were also determined. |
2022-06-13 |
2023-08-14 |
rat |
| Hailan Liu, Xing Cai, Yanlin He, Yong X. Hyperactivity of a midbrain dopamine to 5-HT circuit causes anorexia. Journal of molecular cell biology. 2022-05-25. PMID:35612989. |
hyperactivity of a midbrain dopamine to 5-ht circuit causes anorexia. |
2022-05-25 |
2023-08-13 |
Not clear |
| Tetsuo Ono, Kodai Hino, Tomoko Kimura, Yasuhiro Uchimura, Takashi Ashihara, Takako Higa, Hideto Kojima, Takashi Murakami, Jun Udagaw. Excessive folic acid intake combined with undernutrition during gestation alters offspring behavior and brain monoamine profiles. Congenital anomalies. 2022-05-09. PMID:35531602. |
these behavioral changes were accompanied by reduced dopamine in the prefrontal cortex (pfc), norepinephrine in the amygdala, and 5-hydroxytryptamine (5-ht) in the dorsal midbrain (dm), pfc, and amygdala where 5-ht neurons project from the dm. |
2022-05-09 |
2023-08-13 |
Not clear |
| Xing Cai, Hailan Liu, Bing Feng, Meng Yu, Yang He, Hesong Liu, Chen Liang, Yongjie Yang, Longlong Tu, Nan Zhang, Lina Wang, Na Yin, Junying Han, Zili Yan, Chunmei Wang, Pingwen Xu, Qi Wu, Qingchun Tong, Yanlin He, Yong X. A D2 to D1 shift in dopaminergic inputs to midbrain 5-HT neurons causes anorexia in mice. Nature neuroscience. 2022-05-02. PMID:35501380. |
a d2 to d1 shift in dopaminergic inputs to midbrain 5-ht neurons causes anorexia in mice. |
2022-05-02 |
2023-08-13 |
mouse |
| Xing Cai, Hailan Liu, Bing Feng, Meng Yu, Yang He, Hesong Liu, Chen Liang, Yongjie Yang, Longlong Tu, Nan Zhang, Lina Wang, Na Yin, Junying Han, Zili Yan, Chunmei Wang, Pingwen Xu, Qi Wu, Qingchun Tong, Yanlin He, Yong X. A D2 to D1 shift in dopaminergic inputs to midbrain 5-HT neurons causes anorexia in mice. Nature neuroscience. 2022-05-02. PMID:35501380. |
midbrain dopamine (da) and serotonin (5-ht) neurons regulate motivated behaviors, including feeding, but less is known about how these circuits may interact. |
2022-05-02 |
2023-08-13 |
mouse |
| Divya Yadav, Pravir Kuma. Restoration and targeting of aberrant neurotransmitters in Parkinson's disease therapeutics. Neurochemistry international. 2022-03-25. PMID:35331828. |
parkinson's disease (pd) occurs due to extensive damage of dopamine-producing neurons; this causes dopamine deficits in the midbrain, followed by the alternation of various other neurotransmitters (glutamate, gaba, serotonin, etc.). |
2022-03-25 |
2023-08-13 |
Not clear |
| Merel Dagher, Katie A Perrotta, Sara A Erwin, Ayaka Hachisuka, Rahul Iyer, Sotiris C Masmanidis, Hongyan Yang, Anne M Andrew. Optogenetic Stimulation of Midbrain Dopamine Neurons Produces Striatal Serotonin Release. ACS chemical neuroscience. 2022-03-21. PMID:35312275. |
optogenetic stimulation of midbrain dopamine neurons produces striatal serotonin release. |
2022-03-21 |
2023-08-13 |
mouse |
| Blake A Kimmey, Ruthie E Wittenberg, Alexandra Croicu, Nikita Shadani, Alexey Ostroumov, John A Dan. The serotonin 2A receptor agonist TCB-2 attenuates heavy alcohol drinking and alcohol-induced midbrain inhibitory plasticity. Addiction biology. vol 27. issue 2. 2022-03-01. PMID:35229942. |
the serotonin 2a receptor agonist tcb-2 attenuates heavy alcohol drinking and alcohol-induced midbrain inhibitory plasticity. |
2022-03-01 |
2023-08-13 |
Not clear |
| Hidenao Kimijima, Kazuya Miyagawa, Kazuhiro Kurokawa, Atsumi Mochida-Saito, Kohei Takahashi, Hiroshi Takeda, Minoru Tsuj. Trichostatin A, a histone deacetylase inhibitor, alleviates the emotional abnormality induced by maladaptation to stress in mice. Neuroscience letters. vol 766. 2021-12-01. PMID:34774702. |
a biochemical study showed that tryptophan hydroxylase, the rate-limiting enzyme in serotonin (5-ht) synthesis, was increased in midbrain containing raphe nuclei obtained from stress-adapted mice that were chronically treated with tsa 2 h before daily stress exposure. |
2021-12-01 |
2023-08-13 |
mouse |
| Olga E Redina, Vladimir N Babenko, Dmitry A Smagin, Irina L Kovalenko, Anna G Galyamina, Natalia N Kudryavtsev. Correlation of Expression Changes between Genes Controlling 5-HT Synthesis and Genes Genes. vol 12. issue 11. 2021-11-29. PMID:34828419. |
correlation of expression changes between genes controlling 5-ht synthesis and genes midbrain raphe nuclei (mrns) contain a large number of serotonergic neurons associated with the regulation of numerous types of psychoemotional states and physiological processes. |
2021-11-29 |
2023-08-13 |
mouse |
| Nora L Salaberry, Jorge Mendoz. The circadian clock in the mouse habenula is set by catecholamines. Cell and tissue research. 2021-11-24. PMID:34816282. |
anatomically, the hb projects to the midbrain dopamine (da) and serotonin (5-ht) systems, and it receives inputs from the forebrain, midbrain, and brainstem. |
2021-11-24 |
2023-08-13 |
mouse |
| Jana Haase, Aimée K C Jones, Conor J Mc Veigh, Eric Brown, Gerard Clarke, Gudrun Ahnert-Hilge. Sex and brain region-specific regulation of serotonin transporter activity in synaptosomes in guanine nucleotide-binding protein G(q) alpha knockout mice. Journal of neurochemistry. vol 159. issue 1. 2021-11-17. PMID:34309872. |
in the absence of gαq, sert-mediated uptake of 5-hydroxytryptamine (5ht) was enhanced in midbrain and frontal cortex synaptosomes, but only in female mice. |
2021-11-17 |
2023-08-13 |
mouse |
| Zachary A Grieb, Emma G Ford, Mahircan Yagan, Billy Y B Lau, Fredric P Manfredsson, Keerthi Krishnan, Joseph S Lonstei. Oxytocin receptors in the midbrain dorsal raphe are essential for postpartum maternal social and affective behaviors. Psychoneuroendocrinology. vol 131. 2021-11-12. PMID:34182251. |
oxytocin receptors (otrs) in the midbrain dorsal raphe (dr; the source of most forebrain serotonin) have recently been identified as a potential pharmacological target for treating numerous psychiatric disorders. |
2021-11-12 |
2023-08-13 |
Not clear |
| Seong W Kan. Central Nervous System Associated With Light Perception and Physiological Responses of Birds. Frontiers in physiology. vol 12. 2021-11-10. PMID:34744764. |
although further research is required to establish the functional role of opn4 in the ventral tegmental area (vta), dorsal raphe nucleus, and caudal raphe nucleus in the light perception and physiological responses of birds, it is an exciting prospect because the previous results in birds support this hypothesis that opn4 in the midbrain da and serotonin neurons may play significant roles on the light-induced welfare of birds. |
2021-11-10 |
2023-08-13 |
Not clear |
| Xiaohong Huang, Shihuan Kuang, Todd J Applegate, Tsang-Long Lin, Heng-Wei Chen. Prenatal Serotonin Fluctuation Affects Serotoninergic Development and Related Neural Circuits in Chicken Embryos. Neuroscience. vol 473. 2021-10-01. PMID:34425158. |
5-ht exposure mainly affected the neural development in the pons and midbrain, altered the serotoninergic and dopaminergic (daergic) neuronal morphology, nucleus distribution, and their metabolisms and related gene expressions. |
2021-10-01 |
2023-08-13 |
chicken |
| Iulia Zoicas, Sabine E Huber, Liubov S Kalinichenko, Erich Gulbins, Christian P Müller, Johannes Kornhube. Ceramides affect alcohol consumption and depressive-like and anxiety-like behavior in a brain region- and ceramide species-specific way in male mice. Addiction biology. vol 25. issue 6. 2021-09-28. PMID:31828921. |
our results revealed that c16, but not c8 and c20, ceramide altered alcohol drinking and emotional behavior in a brain region-specific way without altering tissue noradrenaline, dopamine, and serotonin levels in the prefrontal cortex, ventral striatum, and dorsal mesencephalon. |
2021-09-28 |
2023-08-13 |
mouse |