| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hajime Shiotani, Muneaki Miyata, Takeshi Kameyama, Kenji Mandai, Miwako Yamasaki, Masahiko Watanabe, Kiyohito Mizutani, Yoshimi Taka. Nectin-2α is localized at cholinergic neuron dendrites and regulates synapse formation in the medial habenula. The Journal of comparative neurology. vol 529. issue 2. 2021-07-13. PMID:32452538. |
the medial habenula (mhb) receives afferents from the triangular septum and the medial septal complex, projects efferents to the interpeduncular nucleus (ipn) in the midbrain to regulate dopamine and serotonin levels, and is implicated in stress, depression, memory, and nicotine withdrawal syndrome. |
2021-07-13 |
2023-08-13 |
Not clear |
| Thatiane De Oliveira Sergio, Alana Tercino Frias, Heloisa Helena Vilela-Costa, Danielle Cg De Oliveira, Antônio W Zuardi, Hélio Zangross. Serotonin mediates the panicolytic-like effect of oxytocin in the dorsal periaqueductal gray. Journal of psychopharmacology (Oxford, England). vol 34. issue 4. 2021-06-25. PMID:32108540. |
this study aimed to investigate the consequence of ot injection in the dpag on escape expression and whether facilitation of 5-ht neurotransmission in this midbrain area is implicated in this action. |
2021-06-25 |
2023-08-13 |
Not clear |
| Sarah E Gartside, Abdurrahman Ercan Yurttaser, Amy L Burns, Nebojša Jovanović, Katie J Smith, Nana Shika Amegashiti, Bas M J Oltho. A role for nitric oxide in serotonin neurons of the midbrain raphe nuclei. The European journal of neuroscience. vol 51. issue 9. 2021-06-21. PMID:32115781. |
a role for nitric oxide in serotonin neurons of the midbrain raphe nuclei. |
2021-06-21 |
2023-08-13 |
rat |
| Zachary A Grieb, Joseph S Lonstei. Oxytocin receptor expression in the midbrain dorsal raphe is dynamic across female reproduction in rats. Journal of neuroendocrinology. vol 33. issue 2. 2021-06-15. PMID:33427399. |
overall, these results suggest that the rostral subregion of the midbrain dr is uniquely sensitive to oxytocin around the time of parturition, with subpopulations of cells that become more sensitive (i.e., dopamine), less sensitive (i.e., gaba) and show no change (i.e., serotonin) to this neuropeptide. |
2021-06-15 |
2023-08-13 |
rat |
| Kai-Chun Yang, Mu-N Liu, Ying-Jay Liou, Li-Yu Hu, Bang-Hung Yang, Yuan-Hwa Cho. Interleukin-1 family and serotonin transporter in first-episode, drug-naive major depressive disorder: A pilot study. Journal of psychiatric research. vol 135. 2021-05-14. PMID:33493946. |
the serotonin transporter (sert) availability in midbrain, thalamus, caudate, and putamen was examined by single-photon emission computed tomography with |
2021-05-14 |
2023-08-13 |
Not clear |
| Marta Portero-Tresserra, D Rojic-Becker, C Vega-Carbajal, G Guillazo-Blanch, A Vale-Martínez, M Martí-Nicoloviu. Caloric restriction modulates the monoaminergic system and metabolic hormones in aged rats. Scientific reports. vol 10. issue 1. 2021-05-03. PMID:33168891. |
noradrenaline (na), dopamine (da), serotonin (5-ht) and its metabolites were measured by high-performance liquid chromatography with electrochemical detection (hplc-ed) in nine brain regions: cerebellum, pons, midbrain, hypothalamus, thalamus, hippocampus, striatum, frontal cortex, and occipital cortex. |
2021-05-03 |
2023-08-13 |
rat |
| Dasiel O Borroto-Escuela, Patrizia Ambrogini, Barbara Chruścicka, Maria Lindskog, Minerva Crespo-Ramirez, Juan C Hernández-Mondragón, Miguel Perez de la Mora, Harriët Schellekens, Kjell Fux. The Role of Central Serotonin Neurons and 5-HT Heteroreceptor Complexes in the Pathophysiology of Depression: A Historical Perspective and Future Prospects. International journal of molecular sciences. vol 22. issue 4. 2021-04-23. PMID:33672070. |
reduced 5-ht1a auto-receptor function, increased plasticity and trophic activity in the midbrain raphe 5-ht neurons can develop via agonist activation of allosteric receptor-receptor interactions in the 5-ht1a-fgfr1 heterocomplex. |
2021-04-23 |
2023-08-13 |
Not clear |
| Carina Meinke, Meagan A Quinlan, Krista C Paffenroth, Fiona E Harrison, Cristina Fenollar-Ferrer, Rania M Katamish, Isabel Stillman, Sammanda Ramamoorthy, Randy D Blakel. Serotonin Transporter Ala276 Mouse: Novel Model to Assess the Neurochemical and Behavioral Impact of Thr276 Phosphorylation In Vivo. Neurochemical research. 2021-04-08. PMID:33830406. |
similarly, no genotype differences were evident in midbrain or hippocampal 5-ht levels, midbrain and hippocampal sert mrna or midbrain protein levels, nor in midbrain synaptosomal 5-ht uptake kinetics. |
2021-04-08 |
2023-08-13 |
mouse |
| Chaya Shor, Wanhong Zuo, Jean D Eloy, Jiang-Hong Y. The Emerging Role of LHb CaMKII in the Comorbidity of Depressive and Alcohol Use Disorders. International journal of molecular sciences. vol 21. issue 21. 2021-03-26. PMID:33143210. |
recently, interest in the lateral habenula, a small epithalamic brain structure, has increased because it becomes hyperactive in depression and alcohol use disorders, and can inhibit dopamine and serotonin neurons in the midbrain reward center, the hypofunction of which is believed to be a critical contributor to the etiology of depressive disorders and alcohol use disorders as well as their comorbidities. |
2021-03-26 |
2023-08-13 |
Not clear |
| Nikolay N Dygalo, Tatyana S Kalinina, Galina T Shishkin. Stress-induced expression pattern of glutamate signaling genes associated with anhedonia. Stress (Amsterdam, Netherlands). vol 23. issue 6. 2021-03-24. PMID:32814471. |
main features of the expression patterns include the decrease in mrna levels for ampa and nmda subunits in the midbrain and hippocampus that is consistent with the hypothesis that "monoamine (serotonin)-glutamate/gaba long neural circuit" involved in mood regulation. |
2021-03-24 |
2023-08-13 |
human |
| Justin K Siemann, Piper Williams, Turnee N Malik, Chad R Jackson, Noah H Green, Ronald B Emeson, Pat Levitt, Douglas G McMaho. Photoperiodic effects on monoamine signaling and gene expression throughout development in the serotonin and dopamine systems. Scientific reports. vol 10. issue 1. 2020-12-15. PMID:32963273. |
mice that developed under short photoperiods demonstrated elevated midbrain th expression levels, specifically during perinatal development compared to mice raised under long photoperiods, and significantly decreased serotonin and dopamine content throughout the course of development. |
2020-12-15 |
2023-08-13 |
mouse |
| Ismo Makkonen, Raili Riikonen, Jyrki T Kuikka, Hannu Kokki, Joseph P Bressler, Cathleen Marshall, Walter E Kaufman. Brain derived neurotrophic factor and serotonin transporter binding as markers of clinical response to fluoxetine therapy in children with autism. Journal of pediatric neurology : JPN. vol 9. issue 1. 2020-10-01. PMID:29056860. |
we examined serum brain derived neurotrophic factor (bdnf) concentrations and serotonin transporter (sert) binding in the medial frontal cortex and midbrain, measured by single photon emission computed tomography (spect) scanning, in a group of 13 autistic children and adolescents (12 males, one female; age 5-16 years), who were treated for six months with fluoxetine at a dose range of 10-40 mg/day. |
2020-10-01 |
2023-08-13 |
human |
| Justin K Siemann, Noah H Green, Nikhil Reddy, Douglas G McMaho. Sequential Photoperiodic Programing of Serotonin Neurons, Signaling and Behaviors During Prenatal and Postnatal Development. Frontiers in neuroscience. vol 13. 2020-10-01. PMID:31133791. |
here we sought to investigate sensitive periods of prenatal and postnatal development for photoperiodic programming of drn serotonin neurons, midbrain serotonin and metabolite levels along with affective behaviors in adolescence (p30) or adulthood (p50). |
2020-10-01 |
2023-08-13 |
mouse |
| Chao Wei, Xiao Han, Danwei Weng, Qiru Feng, Xiangbing Qi, Jin Li, Minmin Lu. Response dynamics of midbrain dopamine neurons and serotonin neurons to heroin, nicotine, cocaine, and MDMA. Cell discovery. vol 4. 2020-09-30. PMID:30416749. |
response dynamics of midbrain dopamine neurons and serotonin neurons to heroin, nicotine, cocaine, and mdma. |
2020-09-30 |
2023-08-13 |
Not clear |
| Chao Wei, Xiao Han, Danwei Weng, Qiru Feng, Xiangbing Qi, Jin Li, Minmin Lu. Response dynamics of midbrain dopamine neurons and serotonin neurons to heroin, nicotine, cocaine, and MDMA. Cell discovery. vol 4. 2020-09-30. PMID:30416749. |
they are believed to target midbrain dopamine neurons and/or serotonin neurons, but their effects on the dynamic neuronal activity remain unclear in behaving states. |
2020-09-30 |
2023-08-13 |
Not clear |
| Kyoungjune Pak, Seunghyeon Shin, Keunyoung Kim, Ju Won Seok, Seong Jang Kim, In Joo Ki. Memory performance associates with serotonin transporter in midbrain and pons in healthy subjects. Hellenic journal of nuclear medicine. vol 22. issue 3. 2020-05-04. PMID:31587029. |
memory performance associates with serotonin transporter in midbrain and pons in healthy subjects. |
2020-05-04 |
2023-08-13 |
human |
| Jing Ren, Alina Isakova, Drew Friedmann, Jiawei Zeng, Sophie M Grutzner, Albert Pun, Grace Q Zhao, Sai Saroja Kolluru, Ruiyu Wang, Rui Lin, Pengcheng Li, Anan Li, Jennifer L Raymond, Qingming Luo, Minmin Luo, Stephen R Quake, Liqun Lu. Single-cell transcriptomes and whole-brain projections of serotonin neurons in the mouse dorsal and median raphe nuclei. eLife. vol 8. 2020-03-11. PMID:31647409. |
serotonin neurons of the dorsal and median raphe nuclei (dr, mr) collectively innervate the entire forebrain and midbrain, modulating diverse physiology and behavior. |
2020-03-11 |
2023-08-13 |
mouse |
| Carlos A Rodríguez-Saltos, Susan M Lyons, Keith W Sockman, Donna L Mane. Sound-induced monoaminergic turnover in the auditory forebrain depends on endocrine state in a seasonally-breeding songbird. Journal of neuroendocrinology. 2020-03-06. PMID:29738608. |
we then used high performance liquid chromatography to measure turnover of dopamine, norepinephrine, and serotonin in the auditory midbrain and forebrain. |
2020-03-06 |
2023-08-13 |
Not clear |
| Raúl Vieira, María J Mancebo, Jorge José Pérez-Maceira, Manuel Aldegund. Melatonin synthesis in the optic lobes and midbrain of the grasshopper Oedipoda caerulescens. Archives of insect biochemistry and physiology. vol 102. issue 4. 2020-01-02. PMID:31328825. |
in the present study, the levels of mel, metabolites (5-ht, nas, and 5-hiaa) and enzyme nat were determined in the optic lobes and the midbrain of the grasshopper oedipoda caerulescens, in conditions of light and darkness. |
2020-01-02 |
2023-08-13 |
Not clear |
| Raúl Vieira, María J Mancebo, Jorge José Pérez-Maceira, Manuel Aldegund. Melatonin synthesis in the optic lobes and midbrain of the grasshopper Oedipoda caerulescens. Archives of insect biochemistry and physiology. vol 102. issue 4. 2020-01-02. PMID:31328825. |
also, we observed differences in the metabolism of 5-ht between the optic lobes and the midbrain light/dark-dependent. |
2020-01-02 |
2023-08-13 |
Not clear |