| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| X M Guan, W J McBrid. Serotonin microinfusion into the ventral tegmental area increases accumbens dopamine release. Brain research bulletin. vol 23. issue 6. 1990-03-08. PMID:2575444. |
the effects of microinfusion of serotonin (5-ht) agents as well as glutamate and muscimol into the ventral tegmental area (vta) on dopamine (da) release in the ipsilateral nucleus accumbens (acc) were investigated in freely moving rats, using a push-pull perfusion procedure. |
1990-03-08 |
2023-08-11 |
rat |
| X M Guan, W J McBrid. Serotonin microinfusion into the ventral tegmental area increases accumbens dopamine release. Brain research bulletin. vol 23. issue 6. 1990-03-08. PMID:2575444. |
administration of 2 micrograms 5-ht into the vta caused a significant (p less than 0.05) elevation in the perfusate levels of dopac (80%) and hva (70%) over baseline values. |
1990-03-08 |
2023-08-11 |
rat |
| X M Guan, W J McBrid. Serotonin microinfusion into the ventral tegmental area increases accumbens dopamine release. Brain research bulletin. vol 23. issue 6. 1990-03-08. PMID:2575444. |
the results suggest that 5-ht innervations in the vta may have an excitatory action possibly via 5-ht1b rather than 5-ht1a receptors on the mesolimbic da system projecting to the acc and that this da system may also be regulated by glutamatergic and gabaergic (via gabaa receptors) inputs. |
1990-03-08 |
2023-08-11 |
rat |
| B E Jones, A C Cuell. Afferents to the basal forebrain cholinergic cell area from pontomesencephalic--catecholamine, serotonin, and acetylcholine--neurons. Neuroscience. vol 31. issue 1. 1989-10-06. PMID:2475819. |
of the total population of retrogradely labelled neurons, a significant (approximately 25%) proportion were tyrosine hydroxylase-immunoreactive and found in the ventral tegmental area (a10), the substantia nigra (a9), the retrorubral field (a8), the raphe nuclei (dorsalis, linearis and interfascicularis) and the locus coeruleus nucleus (a6), another important contingent (approximately 10%) was represented by serotonin neurons of the dorsal raphe nucleus (b7), the central superior nucleus (b8) and ventral tegmentum (b9). |
1989-10-06 |
2023-08-11 |
Not clear |
| A Kalsbeek, J P de Bruin, M A Matthijssen, H B Uyling. Ontogeny of open field activity in rats after neonatal lesioning of the mesocortical dopaminergic projection. Behavioural brain research. vol 32. issue 2. 1989-05-04. PMID:2923656. |
medial vta lesions caused a moderate dopamine depletion in the prefrontal cortex and an almost complete cortical serotonin depletion, and resulted in transient hyperactivity in the open field at postnatal day 25. |
1989-05-04 |
2023-08-11 |
rat |
| D Hervé, V M Pickel, T H Joh, A Beaude. Serotonin axon terminals in the ventral tegmental area of the rat: fine structure and synaptic input to dopaminergic neurons. Brain research. vol 435. issue 1-2. 1988-03-10. PMID:2892580. |
the serotoninergic (5-hydroxytryptamine, 5-ht) innervation of the rat ventral tegmental area (vta) was examined by light and electron microscopic radioautography following intraventricular infusion of [3h]5-ht. |
1988-03-10 |
2023-08-11 |
rat |
| D Hervé, V M Pickel, T H Joh, A Beaude. Serotonin axon terminals in the ventral tegmental area of the rat: fine structure and synaptic input to dopaminergic neurons. Brain research. vol 435. issue 1-2. 1988-03-10. PMID:2892580. |
by light microscopy, [3h]5-ht labeled axons and axonal varicosities were detected throughout the interfascicular nucleus and ventral portion of the vta. |
1988-03-10 |
2023-08-11 |
rat |
| D Hervé, V M Pickel, T H Joh, A Beaude. Serotonin axon terminals in the ventral tegmental area of the rat: fine structure and synaptic input to dopaminergic neurons. Brain research. vol 435. issue 1-2. 1988-03-10. PMID:2892580. |
based on the probability of seeing such synaptic specializations in single thin sections, it was estimated that as many as 50% of the labeled 5-ht terminals formed synaptic contacts in the vta. |
1988-03-10 |
2023-08-11 |
rat |
| D Hervé, V M Pickel, T H Joh, A Beaude. Serotonin axon terminals in the ventral tegmental area of the rat: fine structure and synaptic input to dopaminergic neurons. Brain research. vol 435. issue 1-2. 1988-03-10. PMID:2892580. |
electron microscopy demonstrated that terminals with radioautographic labeling for 5-ht formed conventional synapses both with th-labeled and unlabeled dendrites in the vta. |
1988-03-10 |
2023-08-11 |
rat |
| D Hervé, V M Pickel, T H Joh, A Beaude. Serotonin axon terminals in the ventral tegmental area of the rat: fine structure and synaptic input to dopaminergic neurons. Brain research. vol 435. issue 1-2. 1988-03-10. PMID:2892580. |
these results suggest that 5-ht neurons innervate both dopaminergic and non-dopaminergic neurons in the vta and may influence mesocortical and mesolimbic efferent systems through synaptic as well as non-synaptic mechanisms. |
1988-03-10 |
2023-08-11 |
rat |
| M D Diaz Palarea, M C Gonzalez, M Rodrigue. Behavioral lateralization in the T-maze and monoaminergic brain asymmetries. Physiology & behavior. vol 40. issue 6. 1987-12-15. PMID:3671548. |
there were no significant differences for serotonin or norepinephrine between the t-maze preferred and non-preferred brain sides in the s. nigra, ventral tegmental area, striatum, acumbens, frontal lobe or hippocampus. |
1987-12-15 |
2023-08-11 |
rat |
| K Mori, H Shimabukuro, K Yamashiro, H Miyake, T Kawan. Spasmodic head movements produced by destruction of unilateral ventromedial tegmentum in cats. Applied neurophysiology. vol 48. issue 1-6. 1986-09-16. PMID:2427026. |
in cats, unilateral electrolytic destruction in the dorsomedial parts of the ventral tegmental area (vta) (tsai) led to the appearance of torticollic rotatory head postures associated with a marked drop of the corresponding caudate serotonin. |
1986-09-16 |
2023-08-11 |
Not clear |
| E Widerlöv, P W Kalivas, M H Lewis, A J Prange, G R Brees. Influence of cholecystokinin on central monoaminergic pathways. Regulatory peptides. vol 6. issue 2. 1983-09-23. PMID:6308717. |
the contents of da and its main metabolites, dihydroxyphenylacetic acid and homovanillic acid, together with serotonin and its main metabolite, 5-hydroxyindoleacetic acid (5-hiaa), were measured in different brain areas after direct injection of cck-8 into the ventral tegmental area (a10) or nucleus accumbens. |
1983-09-23 |
2023-08-12 |
rat |
| M L Maye. Electrophysiological analysis of inhibitory synaptic mechanisms in the preoptic area of the rat. The Journal of physiology. vol 316. 1982-03-13. PMID:7320870. |
reduction of hypothalamic serotonin (5-ht) levels to about 40% of control values by micro-injection of 5,7-dihydroxytryptamine into the ventral tegmental area, or parenteral injection of parachlorophenylalanine, did not alter the profile of responses evoked by either arcuate-ventromedial or periaqueductal grey stimulation. |
1982-03-13 |
2023-08-12 |
rat |
| W R Crowley, T L O'Donohue, E A Muth, D M Jacobowit. Effects of ovarian hormones on levels of luteinizing hormone in plasma and on serotonin concentrations in discrete brain nuclei. Brain research bulletin. vol 4. issue 4. 1979-12-20. PMID:487210. |
progesterone alone elevated serotonin content in the nucleus tractus diagonalis and ventral tegmental area. |
1979-12-20 |
2023-08-11 |
rat |
| R Y Moore, A E Halaris, B E Jone. Serotonin neurons of the midbrain raphe: ascending projections. The Journal of comparative neurology. vol 180. issue 3. 1978-09-01. PMID:77865. |
axons of raphe serotonin neurons ascend in the ventral tegmental area and enter the medial forebrain bundle. |
1978-09-01 |
2023-08-11 |
rat |