| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M S Brodie, R D Trifunović, S A Shefne. Serotonin potentiates ethanol-induced excitation of ventral tegmental area neurons in brain slices from three different rat strains. The Journal of pharmacology and experimental therapeutics. vol 273. issue 3. 1995-07-21. PMID:7791084. |
the effect of 160 mm ethanol on vta neurons from fischer 344 rats, for example, was increased from 38.5 +/- 6.1% before serotonin to 77.4 +/- 16.7% after administration of 10 microm serotonin. |
1995-07-21 |
2023-08-12 |
rat |
| M S Brodie, R D Trifunović, S A Shefne. Serotonin potentiates ethanol-induced excitation of ventral tegmental area neurons in brain slices from three different rat strains. The Journal of pharmacology and experimental therapeutics. vol 273. issue 3. 1995-07-21. PMID:7791084. |
the action of serotonin to increase the potency of ethanol to excite vta neurons may be an important factor in the rewarding effects of ethanol, and might be exploited to develop effective pharmacotherapeutic agents for the treatment of alcohol craving. |
1995-07-21 |
2023-08-12 |
rat |
| W J McBride, J M Murphy, G J Gatto, A D Levy, K Yoshimoto, L Lumeng, T K L. CNS mechanisms of alcohol self-administration. Alcohol and alcoholism (Oxford, Oxfordshire). Supplement. vol 2. 1995-06-22. PMID:7748340. |
neurochemical and neuropharmacological studies were undertaken to examine the possible involvement of the ventral tegmental area (vta) dopamine (da) system and the dorsal raphe nucleus (drn) serotonin (5-ht) system in regulating oral alcohol self-administration. |
1995-06-22 |
2023-08-12 |
rat |
| W J McBride, J M Murphy, G J Gatto, A D Levy, K Yoshimoto, L Lumeng, T K L. CNS mechanisms of alcohol self-administration. Alcohol and alcoholism (Oxford, Oxfordshire). Supplement. vol 2. 1995-06-22. PMID:7748340. |
overall, these results suggest an innate abnormal functioning of the vta da and drn 5-ht systems may be key factors facilitating the rewarding actions of ethanol in the cns of p rats. |
1995-06-22 |
2023-08-12 |
rat |
| N H Chen, M E Reit. Monoamine interactions measured by microdialysis in the ventral tegmental area of rats treated systemically with (+/-)-8-hydroxy-2-(di-n-propylamino)tetralin. Journal of neurochemistry. vol 64. issue 4. 1995-04-18. PMID:7891086. |
the effect of (+/-)-8-hydroxy-2-(di-n-propyl-amino)tetralin (8-oh-dpat), a selective serotonin 5-ht1a agonist, on levels of extracellular norepinephrine (ne), dopamine (da), and 5-ht (measured simultaneously) was investigated by microdialysis in the ventral tegmental area (vta) of freely moving rats, and their behavioral activity was monitored. |
1995-04-18 |
2023-08-12 |
rat |
| N H Chen, M E Reit. Monoamine interactions measured by microdialysis in the ventral tegmental area of rats treated systemically with (+/-)-8-hydroxy-2-(di-n-propylamino)tetralin. Journal of neurochemistry. vol 64. issue 4. 1995-04-18. PMID:7891086. |
at 50 micrograms/kg s.c., 8-oh-dpat reduced 5-ht levels but enhanced ne and da levels in vta dialysate. |
1995-04-18 |
2023-08-12 |
rat |
| M E Rice, C D Richards, S Nedergaard, J Hounsgaard, C Nicholson, S A Greenfiel. Direct monitoring of dopamine and 5-HT release in substantia nigra and ventral tegmental area in vitro. Experimental brain research. vol 100. issue 3. 1995-02-08. PMID:7813678. |
direct monitoring of dopamine and 5-ht release in substantia nigra and ventral tegmental area in vitro. |
1995-02-08 |
2023-08-12 |
Not clear |
| M E Rice, C D Richards, S Nedergaard, J Hounsgaard, C Nicholson, S A Greenfiel. Direct monitoring of dopamine and 5-HT release in substantia nigra and ventral tegmental area in vitro. Experimental brain research. vol 100. issue 3. 1995-02-08. PMID:7813678. |
fast-scan cyclic voltammetry with carbon fibre microelectrodes was used to detect endogenous dopamine (da) and 5-hydroxytryptamine (5-ht) release from three distinct regions of guinea-pig mid-brain in vitro: rostral and caudal substantia nigra (sn) and the ventral tegmental area (vta). |
1995-02-08 |
2023-08-12 |
Not clear |
| M Fujita, S Shimada, K Fukuchi, M Tohyama, T Nishimur. Distribution of cocaine recognition sites in rat brain: in vitro and ex vivo autoradiography with [125I]RTI-55. Journal of chemical neuroanatomy. vol 7. issue 1-2. 1995-01-31. PMID:7802967. |
further, in the presence of clomipramine, a selective ligand for 5htt, [125i]rti-55 binding was remarkably inhibited in the midline and lateral geniculate nuclei of the thalamus, the hypothalamic nuclei, the superior colliculus, the dorsal raphe nucleus, and the facial nucleus, while [125i]rti-55 binding remained in the olfactory tubercle, the caudate putamen, the accumbens nucleus, the substantia nigra compact part, the subthalamic nucleus, and the ventral tegmental area. |
1995-01-31 |
2023-08-12 |
rat |
| M Gobbi, M C Regondi, M Pompeiano, J M Palacios, T Mennin. Differential effects of 5,7-dihydroxytryptamine-induced serotoninergic degeneration of 5-HT1A receptors and 5-HT uptake sites in the rat brain. Journal of chemical neuroanatomy. vol 7. issue 1-2. 1995-01-31. PMID:7802971. |
in the caudate putamen these binding sites were significantly decreased only 14 days after the lesion, whereas the ventral tegmental area (or the enclosed median forebrain bundle), the dorsal raphe (mainly the ventral portion) and the median raphe maintained their high density of serotonin uptake sites even after 14 days. |
1995-01-31 |
2023-08-12 |
rat |
| N H Chen, M E Reit. Autoregulation and monoamine interactions in the ventral tegmental area in the absence and presence of cocaine: a microdialysis study in freely moving rats. The Journal of pharmacology and experimental therapeutics. vol 271. issue 3. 1995-01-17. PMID:7996474. |
extracellular levels of norepinephrine (ne), dopamine (da) and serotonin (5-ht) were measured simultaneously by microdialysis in the ventral tegmental area (vta) of conscious rats, and locomotor activity was monitored. |
1995-01-17 |
2023-08-12 |
rat |
| M Pessia, Z G Jiang, R A North, S W Johnso. Actions of 5-hydroxytryptamine on ventral tegmental area neurons of the rat in vitro. Brain research. vol 654. issue 2. 1995-01-09. PMID:7987681. |
actions of 5-hydroxytryptamine on ventral tegmental area neurons of the rat in vitro. |
1995-01-09 |
2023-08-12 |
rat |
| D L Cameron, J T William. Cocaine inhibits GABA release in the VTA through endogenous 5-HT. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 14. issue 11 Pt 1. 1994-12-06. PMID:7965077. |
cocaine inhibits gaba release in the vta through endogenous 5-ht. |
1994-12-06 |
2023-08-12 |
Not clear |
| S Prisco, S Pagannone, E Esposit. Serotonin-dopamine interaction in the rat ventral tegmental area: an electrophysiological study in vivo. The Journal of pharmacology and experimental therapeutics. vol 271. issue 1. 1994-11-25. PMID:7965760. |
electrophysiological techniques were used to study the effects of various serotonin (5-ht) agonists and antagonists on the activity of dopamine (da) neurons in the ventral tegmental area (vta) of rats. |
1994-11-25 |
2023-08-12 |
rat |
| E J Van Bockstaele, D M Cestari, V M Picke. Synaptic structure and connectivity of serotonin terminals in the ventral tegmental area: potential sites for modulation of mesolimbic dopamine neurons. Brain research. vol 647. issue 2. 1994-11-10. PMID:7522922. |
synaptic structure and connectivity of serotonin terminals in the ventral tegmental area: potential sites for modulation of mesolimbic dopamine neurons. |
1994-11-10 |
2023-08-12 |
rat |
| E J Van Bockstaele, D M Cestari, V M Picke. Synaptic structure and connectivity of serotonin terminals in the ventral tegmental area: potential sites for modulation of mesolimbic dopamine neurons. Brain research. vol 647. issue 2. 1994-11-10. PMID:7522922. |
microinfusion of serotonin (5-hydroxytryptamine; 5-ht) into the ventral tegmental area enhances the release of dopamine in the nucleus accumbens, a major target of midbrain dopamine neurons. |
1994-11-10 |
2023-08-12 |
rat |
| E J Van Bockstaele, D M Cestari, V M Picke. Synaptic structure and connectivity of serotonin terminals in the ventral tegmental area: potential sites for modulation of mesolimbic dopamine neurons. Brain research. vol 647. issue 2. 1994-11-10. PMID:7522922. |
we examined the synaptic basis for 5-ht modulation of neurons in the ventral tegmental area which either (i) project to the nucleus accumbens or (ii) contain the catecholamine synthesizing enzyme tyrosine hydroxylase, a marker of dopamine neurons in this brain region. |
1994-11-10 |
2023-08-12 |
rat |
| E J Van Bockstaele, D M Cestari, V M Picke. Synaptic structure and connectivity of serotonin terminals in the ventral tegmental area: potential sites for modulation of mesolimbic dopamine neurons. Brain research. vol 647. issue 2. 1994-11-10. PMID:7522922. |
in the first study, immunoperoxidase labeling of 5-ht in the ventral tegmental area was combined with retrograde transport of gold particles following unilateral injections of the tracer into the nucleus accumbens of adult rats. |
1994-11-10 |
2023-08-12 |
rat |
| S Ueda, M Kawat. Regeneration of serotonergic immunoreactive fibers in the brain of 5,6-dihydroxytryptamine treated rat. Journal fur Hirnforschung. vol 35. issue 1. 1994-08-04. PMID:8021452. |
degenerative serotonergic fibers characterized by droplet-like swelling and intense staining by serotonin antiserum were detected in the following discrete areas, e.g., medial forebrain bundle (mfb), cingulate cortex, septal nucleus, diagonal band of broca (dbb), lateral preoptic area, bed nucleus of stria terminalis, perifornical area, stria-terminals, raphe nuclei, ventral tegmental area, periaqueductal gray lateral reticular nucleus and nucleus of the solitary tract. |
1994-08-04 |
2023-08-12 |
rat |
| L H Parsons, J B Justic. Serotonin and dopamine sensitization in the nucleus accumbens, ventral tegmental area, and dorsal raphe nucleus following repeated cocaine administration. Journal of neurochemistry. vol 61. issue 5. 1993-11-29. PMID:7693863. |
serotonin and dopamine sensitization in the nucleus accumbens, ventral tegmental area, and dorsal raphe nucleus following repeated cocaine administration. |
1993-11-29 |
2023-08-12 |
rat |