| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Q S Yan, M E Reith, P C Jobe, J W Daile. Focal ethanol elevates extracellular dopamine and serotonin concentrations in the rat ventral tegmental area. European journal of pharmacology. vol 301. issue 1-3. 1997-02-04. PMID:8773446. |
focal ethanol elevates extracellular dopamine and serotonin concentrations in the rat ventral tegmental area. |
1997-02-04 |
2023-08-12 |
rat |
| Q S Yan, M E Reith, P C Jobe, J W Daile. Focal ethanol elevates extracellular dopamine and serotonin concentrations in the rat ventral tegmental area. European journal of pharmacology. vol 301. issue 1-3. 1997-02-04. PMID:8773446. |
the present study describes the effects of local perfusion with ethanol on extracellular dopamine and serotonin (5-hydroxytryptamine, 5-ht) concentrations in the ventral tegmental area. |
1997-02-04 |
2023-08-12 |
rat |
| Q S Yan, M E Reith, P C Jobe, J W Daile. Focal ethanol elevates extracellular dopamine and serotonin concentrations in the rat ventral tegmental area. European journal of pharmacology. vol 301. issue 1-3. 1997-02-04. PMID:8773446. |
perfusion with 100 mm k+ before and after infusion of 10% ethanol revealed that the second perfusion with high k+ solution still produced an increase in dopamine and serotonin concentration, similar in magnitude to the first response, indicating that perfusion with 10% ethanol did not cause irreversible damage to either dopamine cell bodies or serotonin terminals in the ventral tegmental area. |
1997-02-04 |
2023-08-12 |
rat |
| Q S Yan, M E Reith, P C Jobe, J W Daile. Focal ethanol elevates extracellular dopamine and serotonin concentrations in the rat ventral tegmental area. European journal of pharmacology. vol 301. issue 1-3. 1997-02-04. PMID:8773446. |
these results suggest that dopamine and serotonin release from the ventral tegmental area produced by focal application of 10% ethanol is mediated, at least in part, by a non-exocytotic mechanism. |
1997-02-04 |
2023-08-12 |
rat |
| J M Woods, M J Drus. Effects of chronic ethanol consumption and aging on dopamine, serotonin, and metabolites. Journal of neurochemistry. vol 66. issue 5. 1997-01-14. PMID:8780050. |
ethanol also significantly lowered 5-ht and 5-hiaa contents in the vta and reduced dopac and 5-hiaa levels in the vp. |
1997-01-14 |
2023-08-12 |
rat |
| E J Mylecharan. Ventral tegmental area 5-HT receptors: mesolimbic dopamine release and behavioural studies. Behavioural brain research. vol 73. issue 1-2. 1996-12-04. PMID:8788468. |
ventral tegmental area 5-ht receptors: mesolimbic dopamine release and behavioural studies. |
1996-12-04 |
2023-08-12 |
rat |
| E J Mylecharan. Ventral tegmental area 5-HT receptors: mesolimbic dopamine release and behavioural studies. Behavioural brain research. vol 73. issue 1-2. 1996-12-04. PMID:8788468. |
this raises the possibility of a vta site of action; as yet, however, relatively little is specifically known about 5-ht receptors and function in the vta. |
1996-12-04 |
2023-08-12 |
rat |
| Y Minabe, K Emori, C R Ashb. The depletion of brain serotonin levels by para-chlorophenylalanine administration significantly alters the activity of midbrain dopamine cells in rats: an extracellular single cell recording study. Synapse (New York, N.Y.). vol 22. issue 1. 1996-11-08. PMID:8822477. |
in this study, we examined the effect of 5-ht depletion produced by the acute administration of para-chlorophenylalanine (pcpa) on the number of spontaneously active dopamine (da) cells in the ventral tegmental area (vta or a10) and substantia nigra pars compacta (snc or a9) in the rat. |
1996-11-08 |
2023-08-12 |
rat |
| D Martin, G Miller, N Fischer, D Diz, T Cullen, D Russel. Glial cell line-derived neurotrophic factor: the lateral cerebral ventricle as a site of administration for stimulation of the substantia nigra dopamine system in rats. The European journal of neuroscience. vol 8. issue 6. 1996-11-06. PMID:8752595. |
rhgdnf had no effect on striatal or substantia nigral serotonin (5-ht) and 5-hydroxyindoleacetic acid levels, but these levels were significantly increased in the ventral tegmental area and hypothalamus respectively. |
1996-11-06 |
2023-08-12 |
human |
| D L Cameron, J T William. Opposing roles for dopamine and serotonin at presynaptic receptors in the ventral tegmental area. Clinical and experimental pharmacology & physiology. vol 22. issue 11. 1996-04-09. PMID:8593741. |
opposing roles for dopamine and serotonin at presynaptic receptors in the ventral tegmental area. |
1996-04-09 |
2023-08-12 |
Not clear |
| D L Cameron, J T William. Opposing roles for dopamine and serotonin at presynaptic receptors in the ventral tegmental area. Clinical and experimental pharmacology & physiology. vol 22. issue 11. 1996-04-09. PMID:8593741. |
the results of this study suggest that dopamine and 5ht have opposing roles in modulating gaba input into vta dopamine neurons. |
1996-04-09 |
2023-08-12 |
Not clear |
| A W Deckel, E Vavrousek-Jakuba, W J Shoemake. Prefrontal levels of 5-HIAA, but not dopamine, predict alcohol consumption in male Wistar rats following 6-OHDA lesions. Alcohol (Fayetteville, N.Y.). vol 12. issue 6. 1996-04-03. PMID:8590620. |
post hoc analyses were run examining the relationship of da and its metabolites, 5-ht and its metabolite (5-hiaa), and norepinephrine (ne) in the mpfc, na, and vta with alcohol consumption. |
1996-04-03 |
2023-08-12 |
rat |
| R D Trifunović, M S Brodi. The effects of clomipramine on the excitatory action of ethanol on dopaminergic neurons of the ventral tegmental area in vitro. The Journal of pharmacology and experimental therapeutics. vol 276. issue 1. 1996-02-26. PMID:8558452. |
we have demonstrated in electrophysiological experiments in brain slices that serotonin potentiates the excitatory effect of ethanol on putative dopaminergic neurons of the vta. |
1996-02-26 |
2023-08-12 |
Not clear |
| R D Trifunović, M S Brodi. The effects of clomipramine on the excitatory action of ethanol on dopaminergic neurons of the ventral tegmental area in vitro. The Journal of pharmacology and experimental therapeutics. vol 276. issue 1. 1996-02-26. PMID:8558452. |
inasmuch as serotonin reuptake inhibitors have been shown to reduce ethanol intake in clinical studies, we investigated the effect of two serotonin reuptake inhibitors, clomipramine and zimelidine, on ethanol-induced excitation of vta neurons recorded in vitro. |
1996-02-26 |
2023-08-12 |
Not clear |
| S Prisco, E Esposit. Differential effects of acute and chronic fluoxetine administration on the spontaneous activity of dopaminergic neurones in the ventral tegmental area. British journal of pharmacology. vol 116. issue 2. 1996-02-01. PMID:8528581. |
5 it is concluded that fluoxetine inhibits dopaminergic function in the vta by enhancing the synaptic levels of 5-ht, which possibly acts through the 5-ht2c/2b receptor subtype. |
1996-02-01 |
2023-08-12 |
rat |
| C F Phelix, P A Broderic. Light microscopic immunocytochemical evidence of converging serotonin and dopamine terminals in ventrolateral nucleus accumbens. Brain research bulletin. vol 37. issue 1. 1995-08-15. PMID:7606477. |
these monoaminergic neurons consist of the serotonergic (5-ht) neurons of the dorsal and median raphe and the dopaminergic (da) neurons of the ventral tegmental area (vta). |
1995-08-15 |
2023-08-12 |
rat |
| N Bonhomme, M Cador, L Stinus, M Le Moal, U Spampinat. Short and long-term changes in dopamine and serotonin receptor binding sites in amphetamine-sensitized rats: a quantitative autoradiographic study. Brain research. vol 675. issue 1-2. 1995-08-03. PMID:7796132. |
quantitative autoradiographic analysis of da and serotonin 5-ht receptor subtypes was performed in the following brain regions: medial prefrontal cortex, nucleus accumbens, striatum, substantia nigra, ventral tegmental area, dorsal and median raphe nuclei. |
1995-08-03 |
2023-08-12 |
rat |
| M S Brodie, R D Trifunović, S A Shefne. Serotonin potentiates ethanol-induced excitation of ventral tegmental area neurons in brain slices from three different rat strains. The Journal of pharmacology and experimental therapeutics. vol 273. issue 3. 1995-07-21. PMID:7791084. |
serotonin potentiates ethanol-induced excitation of ventral tegmental area neurons in brain slices from three different rat strains. |
1995-07-21 |
2023-08-12 |
rat |
| M S Brodie, R D Trifunović, S A Shefne. Serotonin potentiates ethanol-induced excitation of ventral tegmental area neurons in brain slices from three different rat strains. The Journal of pharmacology and experimental therapeutics. vol 273. issue 3. 1995-07-21. PMID:7791084. |
in the present study, we tested the interaction between serotonin and ethanol on putative dopamine neurons of the vta. |
1995-07-21 |
2023-08-12 |
rat |
| M S Brodie, R D Trifunović, S A Shefne. Serotonin potentiates ethanol-induced excitation of ventral tegmental area neurons in brain slices from three different rat strains. The Journal of pharmacology and experimental therapeutics. vol 273. issue 3. 1995-07-21. PMID:7791084. |
this potentiation of ethanol excitation by serotonin was seen in vta slices taken from sprague-dawley, fischer 344 and lewis rats. |
1995-07-21 |
2023-08-12 |
rat |