| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Michael Ntim, Qi-Fa Li, Yue Zhang, Xiao-Da Liu, Na Li, Hai-Lun Sun, Xuan Zhang, Bakhtawar Khan, Bin Wang, Qiong Wu, Xue-Fei Wu, Williams Walana, Khizar Khan, Quan-Hong Ma, Jie Zhao, Shao L. TRIM32 Deficiency Impairs Synaptic Plasticity by Excitatory-Inhibitory Imbalance via Notch Pathway. Cerebral cortex (New York, N.Y. : 1991). vol 30. issue 8. 2021-11-29. PMID:32219328. |
trim32 has been linked to several nervous system diseases including autism spectrum disorder, depression, anxiety, and alzheimer's disease. |
2021-11-29 |
2023-08-13 |
mouse |
| Hector Gonzalez, Richard George, Shahzad Muzaffar, Javier Acevedo, Sebastian Hoppner, Christian Mayr, Jerald Yoo, Frank Fitzek, Ibrahim Elfade. Hardware Acceleration of EEG-Based Emotion Classification Systems: A Comprehensive Survey. IEEE transactions on biomedical circuits and systems. vol 15. issue 3. 2021-11-25. PMID:34125683. |
recent years have witnessed a growing interest in eeg-based wearable classifiers of emotions, which could enable the real-time monitoring of patients suffering from neurological disorders such as amyotrophic lateral sclerosis (als), autism spectrum disorder (asd), or alzheimer's. |
2021-11-25 |
2023-08-13 |
Not clear |
| Jessica Cornell, Shelbi Salinas, Hou-Yuan Huang, Miou Zho. Microglia regulation of synaptic plasticity and learning and memory. Neural regeneration research. vol 17. issue 4. 2021-11-10. PMID:34472455. |
these molecules released by microglia can lead to synaptic plasticity and learning and memory deficits associated with aging, alzheimer's disease, traumatic brain injury, hiv-associated neurocognitive disorder, and other neurological or mental disorders such as autism, depression and post-traumatic stress disorder. |
2021-11-10 |
2023-08-13 |
Not clear |
| Yanina Ivashko-Pachima, Illana Goze. Activity-dependent neuroprotective protein (ADNP)-end-binding protein (EB) interactions regulate microtubule dynamics toward protection against tauopathy. Progress in molecular biology and translational science. vol 177. 2021-11-05. PMID:33453943. |
adnp has been found to be mutated in autism, with an estimated prevalence of 0.17% (together, these autism cases now constitute adnp syndrome cases) and our recent results showed somatic mutations in adnp in alzheimer's disease brains correlating with tauopathy. |
2021-11-05 |
2023-08-13 |
mouse |
| Zhen Yan, Benjamin Rei. Mechanisms of synaptic transmission dysregulation in the prefrontal cortex: pathophysiological implications. Molecular psychiatry. 2021-11-05. PMID:33875802. |
dysregulation of pfc synaptic transmission is strongly linked to social deficits, affective disturbance, and memory loss in brain disorders, including autism, schizophrenia, depression, and alzheimer's disease. |
2021-11-05 |
2023-08-13 |
human |
| Kazuya Miyanishi, Arisa Sato, Nanako Kihara, Ryo Utsunomiya, Junya Tanak. Synaptic elimination by microglia and disturbed higher brain functions. Neurochemistry international. vol 142. 2021-10-27. PMID:33181238. |
in addition to the roles of microglia in normal developing and mature brains, impaired microglial phagocytosis functions also correlate with disturbances to these higher brain functions that are caused by neurological, mental, and developmental disorders; parkinson's and alzheimer's diseases, autism spectrum disorder, attention deficit/hyperactivity disorder, and schizophrenia. |
2021-10-27 |
2023-08-13 |
Not clear |
| Valerie F Reyna, Charles J Brainer. Dual Processes in Decision Making and Developmental Neuroscience: A Fuzzy-Trace Model. Developmental review : DR. vol 31. issue 2-3. 2021-10-21. PMID:22096268. |
drawing on research on logical and quantitative reasoning, as well as on risky decision making in the laboratory and in life, we illustrate how the same small set of theoretical principles apply to typical neurodevelopment, encompassing childhood, adolescence, and adulthood, and to neurological conditions such as autism and alzheimer's disease. |
2021-10-21 |
2023-08-12 |
human |
| Cara J Westmark, Crystal M Hervey, Elizabeth M Berry-Kravis, James S Malte. Effect of Anticoagulants on Amyloid β-Protein Precursor and Amyloid Beta Levels in Plasma. Journal of Alzheimer's disease & Parkinsonism. vol 1. 2021-10-21. PMID:23459194. |
altered levels of amyloid β-protein precursor (aβpp) and/or amyloid beta (aβ) are characteristic of several neurological disorders including alzheimer's disease (ad), down syndrome (ds), fragile x syndrome (fxs), parkinson's disease (pd), autism and epilepsy. |
2021-10-21 |
2023-08-12 |
Not clear |
| Subhiksha Subramania. Zebrafish as a model organism - can a fish mimic human? Journal of basic and clinical physiology and pharmacology. 2021-10-18. PMID:34662932. |
this review will try to shed light on the early stages of zebrafish as a model organism and will try to cover the journey of it developing as a successful model organism to map many diseases like diabetes, alzheimer's and autism describing the rationale for using this specific model and briefly the techniques under each category and finally will summarize the pros and cons of the model with its expected future directions. |
2021-10-18 |
2023-08-13 |
human |
| Shira Mencer, Maryam Kartawy, Felix Lendenfeld, Huda Soluh, Manish Kumar Tripathi, Igor Khaliulin, Haitham Ama. Proteomics of autism and Alzheimer's mouse models reveal common alterations in mTOR signaling pathway. Translational psychiatry. vol 11. issue 1. 2021-10-11. PMID:34535637. |
proteomics of autism and alzheimer's mouse models reveal common alterations in mtor signaling pathway. |
2021-10-11 |
2023-08-13 |
mouse |
| Shira Mencer, Maryam Kartawy, Felix Lendenfeld, Huda Soluh, Manish Kumar Tripathi, Igor Khaliulin, Haitham Ama. Proteomics of autism and Alzheimer's mouse models reveal common alterations in mTOR signaling pathway. Translational psychiatry. vol 11. issue 1. 2021-10-11. PMID:34535637. |
autism spectrum disorder (asd) and alzheimer's disease (ad) are two different neurological disorders that share common clinical features, such as language impairment, executive functions, and motor problems. |
2021-10-11 |
2023-08-13 |
mouse |
| Marco Solmi, Luca Bodini, Susanna Cocozza, Mary V Seeman, Eduard Vieta, Elena Dragioti, Andre F Carvalho, Paolo Fusar-Pol. Aripiprazole monotherapy as transdiagnostic intervention for the treatment of mental disorders: An umbrella review according to TRANSD criteria. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 41. 2021-09-23. PMID:33077324. |
aripiprazole outperformed placebo on primary outcomes in alzheimer's disease with behavioral disturbance (ad) (neuropsychiatric symptoms smd 0.20, 95%ci 0.05-0.35, max 15 mg/day), autism spectrum disorder (asd) (severity of symptoms smd 0.39, 95%ci 0.30-0.48, max 15 mg/day), bipolar i disorder (bd) (severity of manic symptoms smd 0.30, 95%ci 0.12-0.47, max 30 mg/day), and schizophrenia/schizoaffective disorder (response rate rr 0.84, 95%ci 0.78-0.92, max 30 mg/day). |
2021-09-23 |
2023-08-13 |
Not clear |
| Zhao Zhang, Guangfei Li, Yong Xu, Xiaoying Tan. Application of Artificial Intelligence in the MRI Classification Task of Human Brain Neurological and Psychiatric Diseases: A Scoping Review. Diagnostics (Basel, Switzerland). vol 11. issue 8. 2021-08-30. PMID:34441336. |
then, the application of ml and dl methods to six typical neurological and psychiatric diseases is summarized, including alzheimer's disease (ad), parkinson's disease (pd), major depressive disorder (mdd), schizophrenia (scz), attention-deficit/hyperactivity disorder (adhd), and autism spectrum disorder (asd). |
2021-08-30 |
2023-08-13 |
human |
| Jian-Wei Zhu, Wei-Qiang Jia, Hui Zhou, Yi-Fei Li, Ming-Ming Zou, Zhao-Tao Wang, Bing-Shan Wu, Ru-Xiang X. Deficiency of TRIM32 Impairs Motor Function and Purkinje Cells in Mid-Aged Mice. Frontiers in aging neuroscience. vol 13. 2021-08-24. PMID:34421574. |
tripartite motif-containing protein 32 (trim32) is an e3 ubiquitin ligase that is involved in balance activities of neurogenesis in the subventricular zone of the mammalian brain and in the development of many nervous system diseases, such as alzheimer's disease, autism spectrum disorder, attention deficit hyperactivity disorder. |
2021-08-24 |
2023-08-13 |
mouse |
| Wen Zhang, Bing-Rui Xiong, Long-Qing Zhang, Xian Huang, Xiaoman Yuan, Yu-Ke Tian, Xue-Bi Tia. The Role of the GABAergic System in Diseases of the Central Nervous System. Neuroscience. vol 470. 2021-08-18. PMID:34242730. |
have also been shown to emerge after abnormalities in the gabaergic system accompanied with concomitant diseases, that include alzheimer's disease (ad), parkinson's disease (pd), autism spectrum disorder (asd), schizophrenia, etc. |
2021-08-18 |
2023-08-13 |
Not clear |
| Martin L Tomov, Alison O'Neil, Hamdah S Abbasi, Beth A Cimini, Anne E Carpenter, Lee L Rubin, Mark Bath. Resolving cell state in iPSC-derived human neural samples with multiplexed fluorescence imaging. Communications biology. vol 4. issue 1. 2021-08-16. PMID:34168275. |
human induced pluripotent stem cell-derived (ipsc) neural cultures offer clinically relevant models of human diseases, including amyotrophic lateral sclerosis, alzheimer's, and autism spectrum disorder. |
2021-08-16 |
2023-08-13 |
human |
| Pradeep Reddy Raamana, Stephen C Strothe. Does size matter? The relationship between predictive power of single-subject morphometric networks to spatial scale and edge weight. Brain structure & function. vol 225. issue 8. 2021-08-11. PMID:32945910. |
an interesting insight generated is that changes in nodal size (spatial scale) have no significant impact on predictive power among the three classification experiments and two disease cohorts studied, i.e., mild cognitive impairment and alzheimer's disease from adni, and autism from the abide dataset. |
2021-08-11 |
2023-08-13 |
Not clear |
| Mattias F Lindberg, Laurent Meije. Dual-Specificity, Tyrosine Phosphorylation-Regulated Kinases (DYRKs) and cdc2-Like Kinases (CLKs) in Human Disease, an Overview. International journal of molecular sciences. vol 22. issue 11. 2021-07-13. PMID:34205123. |
abnormal expression and/or activity of some of these kinases, dyrk1a in particular, is seen in many human nervous system diseases, such as cognitive deficits associated with down syndrome, alzheimer's disease and related diseases, tauopathies, dementia, pick's disease, parkinson's disease and other neurodegenerative diseases, phelan-mcdermid syndrome, autism, and cdkl5 deficiency disorder. |
2021-07-13 |
2023-08-13 |
human |
| Sherri Cofield Kroll, Carole Frances Bennett, Tarah Winter Klinefelte. Update on Neurodegenerative Diseases and Glutamate: A PMHNP Single Case Study Report of a Diagnostically Complex Adult Patient, Interventions, and Unexpected Outcomes. Journal of the American Psychiatric Nurses Association. 2021-07-09. PMID:34238041. |
while dysfunction of serotonin and dopamine neurotransmitters has been studied in depth, in regard to the etiology of mental illness, the neurotransmitter glutamate and its dysfunction is now being explored as contributing to neurodegenerative psychiatric diseases, schizophrenia, autism, depression, and alzheimer's disease. |
2021-07-09 |
2023-08-13 |
Not clear |
| Mingze Yao, Qian Yang, Mengqiao Lian, Pengfei Su, Xiaogang Cui, Tinglin Ren, Xiedong Wang, Changxin Wu, Yaowu Zhen. Generation of Dip2a homozygous knockout murine ES cell line IBMSe001-A-1 via CRISPR/Cas9 technology. Stem cell research. vol 45. 2021-06-21. PMID:32361465. |
dip2a mutation is associated with abnormal brain development and diseases including dyslexia, autism and alzheimer's disease. |
2021-06-21 |
2023-08-13 |
mouse |