| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jean-Michel Paumier, Gopal Thinakara. Matrix metalloproteinase 13, a new target for therapy in Alzheimer's disease. Genes & diseases. vol 6. issue 1. 2020-09-29. PMID:30906825. |
matrix metalloproteinase 13, a new target for therapy in alzheimer's disease. |
2020-09-29 |
2023-08-13 |
Not clear |
| Karolina Minta, Erik Portelius, Shorena Janelidze, Oskar Hansson, Henrik Zetterberg, Kaj Blennow, Ulf Andreasso. Cerebrospinal Fluid Concentrations of Extracellular Matrix Proteins in Alzheimer's Disease. Journal of Alzheimer's disease : JAD. vol 69. issue 4. 2020-09-15. PMID:31156172. |
cerebrospinal fluid concentrations of extracellular matrix proteins in alzheimer's disease. |
2020-09-15 |
2023-08-13 |
Not clear |
| Moira Marizzoni, Clarissa Ferrari, Ambra Macis, Jorge Jovicich, Diego Albani, Claudio Babiloni, Libera Cavaliere, Mira Didic, Gianluigi Forloni, Samantha Galluzzi, Karl-Titus Hoffmann, José Luis Molinuevo, Flavio Nobili, Lucilla Parnetti, Pierre Payoux, Francesca Pizzini, Paolo Maria Rossini, Marco Salvatore, Peter Schönknecht, Andrea Soricelli, Claudio Del Percio, Tilman Hensch, Ulrich Hegerl, Magda Tsolaki, Pieter Jelle Visser, Jens Wiltfang, Jill C Richardson, Régis Bordet, Olivier Blin, Giovanni B Frison. Biomarker Matrix to Track Short Term Disease Progression in Amnestic Mild Cognitive Impairment Patients with Prodromal Alzheimer's Disease. Journal of Alzheimer's disease : JAD. vol 69. issue 1. 2020-09-09. PMID:30958351. |
biomarker matrix to track short term disease progression in amnestic mild cognitive impairment patients with prodromal alzheimer's disease. |
2020-09-09 |
2023-08-13 |
human |
| May J Reed, Mamatha Damodarasamy, William A Bank. The extracellular matrix of the blood-brain barrier: structural and functional roles in health, aging, and Alzheimer's disease. Tissue barriers. vol 7. issue 4. 2020-07-21. PMID:31505997. |
the extracellular matrix of the blood-brain barrier: structural and functional roles in health, aging, and alzheimer's disease. |
2020-07-21 |
2023-08-13 |
Not clear |
| Shumang Zhang, Tongqian Xiao, Yanzhen Yu, Yong Qiao, Zhongjuan Xu, Junsa Geng, Yu Liang, Yan Mei, Qun Dong, Bin Wang, Jiali Wei, Guangli Su. The extracellular matrix enriched with membrane metalloendopeptidase and insulin-degrading enzyme suppresses the deposition of amyloid-beta peptide in Alzheimer's disease cell models. Journal of tissue engineering and regenerative medicine. vol 13. issue 10. 2020-07-16. PMID:31151136. |
the extracellular matrix enriched with membrane metalloendopeptidase and insulin-degrading enzyme suppresses the deposition of amyloid-beta peptide in alzheimer's disease cell models. |
2020-07-16 |
2023-08-13 |
human |
| Juan Du, Sha Li, Yuhong Su, Haidong Wang, Hanjie Liu, Huixian Cu. The role of extracellular matrix metalloproteinase inducer on the action of dihydrotestosterone against the cellular damage induced by Aβ Molecular and cellular endocrinology. vol 498. 2020-06-24. PMID:31401349. |
the role of extracellular matrix metalloproteinase inducer on the action of dihydrotestosterone against the cellular damage induced by aβ clinical studies have revealed that the risk of alzheimer's disease (ad) in men is increased by age-related androgen depletion. |
2020-06-24 |
2023-08-13 |
rat |
| Qi Qiao, Freek G Bouwman, Marleen A van Baak, Johan Renes, Edwin C M Marima. Glucose Restriction Plus Refeeding in Vitro Induce Changes of the Human Adipocyte Secretome with an Impact on Complement Factors and Cathepsins. International journal of molecular sciences. vol 20. issue 16. 2020-01-21. PMID:31434216. |
functional classification revealed gr plus rf-induced changes of enzymes for extracellular matrix modification, complement system factors, cathepsins, and several proteins related to alzheimer's disease. |
2020-01-21 |
2023-08-13 |
human |
| Alessandro Greco, Jon Sanchez Valle, Vera Pancaldi, Anaïs Baudot, Emmanuel Barillot, Michele Caselle, Alfonso Valencia, Andrei Zinovyev, Laura Cantin. Molecular Inverse Comorbidity between Alzheimer's Disease and Lung Cancer: New Insights from Matrix Factorization. International journal of molecular sciences. vol 20. issue 13. 2019-12-06. PMID:31247897. |
molecular inverse comorbidity between alzheimer's disease and lung cancer: new insights from matrix factorization. |
2019-12-06 |
2023-08-13 |
Not clear |
| Ida Emilie Steinmark, Arjuna L James, Pei-Hua Chung, Penny E Morton, Maddy Parsons, Cécile A Dreiss, Christian D Lorenz, Gokhan Yahioglu, Klaus Suhlin. Targeted fluorescence lifetime probes reveal responsive organelle viscosity and membrane fluidity. PloS one. vol 14. issue 2. 2019-11-07. PMID:30763333. |
for demonstration, we image matrix viscosity and membrane fluidity of mitochondria, which have been linked to human diseases, including alzheimer's disease and leigh's syndrome. |
2019-11-07 |
2023-08-13 |
human |
| Jean-Michel Paumier, Nathalie A Py, Laura García-González, Anne Bernard, Delphine Stephan, Laurence Louis, Frédéric Checler, Michel Khrestchatisky, Kévin Baranger, Santiago River. Proamyloidogenic effects of membrane type 1 matrix metalloproteinase involve MMP-2 and BACE-1 activities, and the modulation of APP trafficking. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 33. issue 2. 2019-09-30. PMID:30332299. |
we previously demonstrated that membrane type 1 (mt1) matrix metalloproteinase (mmp) was up-regulated in the hippocampus of the model of transgenic mice bearing 5 familial mutations on human amyloid precursor protein (app) and presenilin 1 of alzheimer disease (ad), and that the proteinase increased the levels of amyloid β peptide (aβ) and its app c-terminal fragment of 99 aa in a heterologous cell system. |
2019-09-30 |
2023-08-13 |
mouse |
| Hedieh Shahpasand-Kroner, Hans-W Klafki, Chris Bauer, Johannes Schuchhardt, Melanie Hüttenrauch, Martina Stazi, Caroline Bouter, Oliver Wirths, Jonathan Vogelgsang, Jens Wiltfan. A two-step immunoassay for the simultaneous assessment of Aβ38, Aβ40 and Aβ42 in human blood plasma supports the Aβ42/Aβ40 ratio as a promising biomarker candidate of Alzheimer's disease. Alzheimer's research & therapy. vol 10. issue 1. 2019-08-30. PMID:30526652. |
the quantification of amyloid-beta (aβ) peptides in blood plasma as potential biomarkers of alzheimer's disease (ad) is hampered by very low aβ concentrations and the presence of matrix components that may interfere with the measurements. |
2019-08-30 |
2023-08-13 |
human |
| Bing-Lin Zhu, Yan Long, Wei Luo, Zhen Yan, Yu-Jie Lai, Li-Ge Zhao, Wei-Hui Zhou, Yan-Jiang Wang, Lin-Lin Shen, Lu Liu, Xiao-Juan Deng, Xue-Feng Wang, Fei Sun, Guo-Jun Che. MMP13 inhibition rescues cognitive decline in Alzheimer transgenic mice via BACE1 regulation. Brain : a journal of neurology. vol 142. issue 1. 2019-08-20. PMID:30596903. |
mmp13 (matrix metallopeptidase 13) plays a key role in bone metabolism and cancer development, but has no known functions in alzheimer's disease. |
2019-08-20 |
2023-08-13 |
mouse |
| Ofek Oren, Victor Banerjee, Ran Taube, Niv Pap. An Aβ42 variant that inhibits intra- and extracellular amyloid aggregation and enhances cell viability. The Biochemical journal. vol 475. issue 19. 2019-05-30. PMID:30213841. |
aggregation and accumulation of the 42-residue amyloid β peptide (aβ42) in the extracellular matrix and within neuronal cells is considered a major cause of neuronal cell cytotoxicity and death in alzheimer's disease (ad) patients. |
2019-05-30 |
2023-08-13 |
Not clear |
| Abhishek Ankur Balmik, Subashchandrabose Chinnathamb. Multi-Faceted Role of Melatonin in Neuroprotection and Amelioration of Tau Aggregates in Alzheimer's Disease. Journal of Alzheimer's disease : JAD. vol 62. issue 4. 2019-05-28. PMID:29562506. |
alzheimer's disease (ad) is one of the major age related neurodegenerative diseases whose pathology arises due to the presence of two distinct protein aggregates, viz., amyloid-β plaques in extracellular matrix and tau neurofibrillary tangles in neurons. |
2019-05-28 |
2023-08-13 |
Not clear |
| Hye Jin Kim, Dongsung Park, Seung Yeop Baek, Seung-Hoon Yang, YoungSoo Kim, Sang Moo Lim, Jinsik Kim, Kyo Seon Hwan. Dielectrophoresis-based filtration effect and detection of amyloid beta in plasma for Alzheimer's disease diagnosis. Biosensors & bioelectronics. vol 128. 2019-05-09. PMID:30660932. |
to demonstrate the filtration effect, the matrix effect was confirmed in standard plasma and in phosphate-buffered saline, based on the detection of amyloid beta (aβ), an alzheimer's disease (ad)-associated peptide. |
2019-05-09 |
2023-08-13 |
Not clear |
| HariOm Singh, Sumitra Nain, Asha Krishnaraj, Sonam Lata, T N Dhol. Genetic variation of matrix metalloproteinase enzyme in HIV-associated neurocognitive disorder. Gene. vol 698. 2019-04-23. PMID:30825593. |
matrix metalloproteinases (mmps) play a key role in several diseases such as rheumatoid arthritis, hiv-associated neurological diseases (hand), multiple sclerosis, osteoporosis, stroke, alzheimer's disease, certain viral infections of the central nervous system, cancer, and hepatitis c virus. |
2019-04-23 |
2023-08-13 |
Not clear |
| Busra Gurel, Mehmet Cansev, Cansu Sevinc, Seda Kelestemur, Busra Ocalan, Aysen Cakir, Sami Aydin, Nevzat Kahveci, Mehmet Ozansoy, Ozlem Taskapilioglu, Ismail Hakki Ulus, Merve Karayel Başar, Betul Sahin, Mete Bora Tuzuner, Ahmet Tarik Bayka. Early Stage Alterations in CA1 Extracellular Region Proteins Indicate Dysregulation of IL6 and Iron Homeostasis in the 5XFAD Alzheimer's Disease Mouse Model. Journal of Alzheimer's disease : JAD. vol 61. issue 4. 2019-01-24. PMID:29376847. |
in recent years, an increasing number of research papers revealed that the compositional and volumetric alterations in the extracellular matrix are the consequences of aging and may be related to alzheimer's disease (ad). |
2019-01-24 |
2023-08-13 |
mouse |
| Feng Ding, Yuna Qian, Zaian Deng, Jitai Zhang, Yongchao Zhou, Lan Yang, Fangyan Wang, Juping Wang, Zhihua Zhou, Jianliang She. Size-selected silver nanoparticles for MALDI-TOF mass spectrometry of amyloid-beta peptides. Nanoscale. vol 10. issue 46. 2018-12-13. PMID:30452045. |
in this study, to explore and compare the efficiency of different sized silver nanoparticles (ag nps) as the maldi matrix for the detection of lmw molecules, three different sized ag nps (2.8 ± 1.0, 12.8 ± 3.2 and 44.2 ± 5.0 nm) have been successfully developed as the maldi time-of-flight ms (maldi-tof ms) matrix and amyloid-beta (aβ) peptides, crucially involved in alzheimer's disease and a variety of cancers, were chosen as an example of lmw molecules in our maldi-tof ms analysis with ag nps as matrices. |
2018-12-13 |
2023-08-13 |
Not clear |
| Manveen K Sethi, Joseph Zai. Extracellular matrix proteomics in schizophrenia and Alzheimer's disease. Analytical and bioanalytical chemistry. vol 409. issue 2. 2018-11-13. PMID:27601046. |
extracellular matrix proteomics in schizophrenia and alzheimer's disease. |
2018-11-13 |
2023-08-13 |
Not clear |
| Mario Díaz, Noemí Fabelo, Isidre Ferrer, Raquel Marí. "Lipid raft aging" in the human frontal cortex during nonpathological aging: gender influences and potential implications in Alzheimer's disease. Neurobiology of aging. vol 67. 2018-10-04. PMID:29627763. |
given the central role of bilayer lipid matrix in lipid rafts functionality and neuronal signaling, we hypothesize that these findings might underlie the higher prevalence of cognitive decline evolving toward alzheimer's disease in postmenopausal women. |
2018-10-04 |
2023-08-13 |
human |