| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Fiona Q Bui, Cassio Luiz Coutinho Almeida-da-Silva, Brandon Huynh, Alston Trinh, Jessica Liu, Jacob Woodward, Homer Asadi, David M Ojciu. Association between periodontal pathogens and systemic disease. Biomedical journal. vol 42. issue 1. 2019-12-12. PMID:30987702. |
these diseases include cardiovascular disease, gastrointestinal and colorectal cancer, diabetes and insulin resistance, and alzheimer's disease, as well as respiratory tract infection and adverse pregnancy outcomes. |
2019-12-12 |
2023-08-13 |
Not clear |
| Firas H Bazzari, Dalaal M Abdallah, Hanan S El-Abha. Chenodeoxycholic Acid Ameliorates AlCl Molecules (Basel, Switzerland). vol 24. issue 10. 2019-11-21. PMID:31137621. |
chenodeoxycholic acid ameliorates alcl insulin resistance is a major risk factor for alzheimer's disease (ad). |
2019-11-21 |
2023-08-13 |
rat |
| Piyali Majumder, Kasturi Roy, Sangram Bagh, Debashis Mukhopadhya. Receptor tyrosine kinases (RTKs) consociate in regulatory clusters in Alzheimer's disease and type 2 diabetes. Molecular and cellular biochemistry. vol 459. issue 1-2. 2019-11-21. PMID:31154588. |
alzheimer's disease (ad) and type 2 diabetes (t2d) share the common hallmark of insulin resistance. |
2019-11-21 |
2023-08-13 |
Not clear |
| Dmitry Petrov, Ignacio Pedrós, Gonzalo Artiach, Francesc X Sureda, Emma Barroso, Mercè Pallàs, Gemma Casadesús, Carlos Beas-Zarate, Eva Carro, Isidro Ferrer, Manuel Vazquez-Carrera, Jaume Folch, Antoni Camin. High-fat diet-induced deregulation of hippocampal insulin signaling and mitochondrial homeostasis deficiences contribute to Alzheimer disease pathology in rodents. Biochimica et biophysica acta. vol 1852. issue 9. 2019-11-20. PMID:26003667. |
high-fat diet-induced deregulation of hippocampal insulin signaling and mitochondrial homeostasis deficiences contribute to alzheimer disease pathology in rodents. |
2019-11-20 |
2023-08-13 |
mouse |
| Bumsup Kwon, Timothy Gamache, Han-Kyu Lee, Henry W Querfurt. Synergistic effects of β-amyloid and ceramide-induced insulin resistance on mitochondrial metabolism in neuronal cells. Biochimica et biophysica acta. vol 1852. issue 9. 2019-11-20. PMID:26022371. |
a large body of evidence support major roles of mitochondrial dysfunction and insulin action in the alzheimer's disease (ad) brain. |
2019-11-20 |
2023-08-13 |
Not clear |
| Masaaki Waragai, Gilbert Ho, Yoshiki Takamatsu, Kazunari Sekiyama, Shuei Sugama, Takato Takenouchi, Eliezer Masliah, Makoto Hashimot. Importance of adiponectin activity in the pathogenesis of Alzheimer's disease. Annals of clinical and translational neurology. vol 4. issue 8. 2019-11-20. PMID:28812049. |
a recent study suggested that insulin resistance may play a central role in the pathogenesis of alzheimer's disease (ad). |
2019-11-20 |
2023-08-13 |
mouse |
| Ramon Velazquez, An Tran, Egide Ishimwe, Larry Denner, Nikhil Dave, Salvatore Oddo, Kelly T Dinele. Corrigendum to "Central insulin dysregulation and energy dyshomeostasis in two mouse models of Alzheimer's disease" [Neurobiol. Aging 58 (2017) 1-13]. Neurobiology of aging. vol 58. 2019-11-20. PMID:28863813. |
corrigendum to "central insulin dysregulation and energy dyshomeostasis in two mouse models of alzheimer's disease" [neurobiol. |
2019-11-20 |
2023-08-13 |
mouse |
| Ramon Velazquez, An Tran, Egide Ishimwe, Larry Denner, Nikhil Dave, Salvatore Oddo, Kelly T Dinele. Corrigendum to "Central insulin dysregulation and energy dyshomeostasis in two mouse models of Alzheimer's disease" [Neurobiol. Aging 58 (2017) 1-13]. Neurobiology of aging. vol 65. 2019-11-20. PMID:29580440. |
corrigendum to "central insulin dysregulation and energy dyshomeostasis in two mouse models of alzheimer's disease" [neurobiol. |
2019-11-20 |
2023-08-13 |
mouse |
| Somayeh Athari Nik Azm, Abolghassem Djazayeri, Majid Safa, Kian Azami, Mahmoud Djalali, Mohammad Sharifzadeh, Mohammadreza Vaf. Probiotics improve insulin resistance status in an experimental model of Alzheimer's disease. Medical journal of the Islamic Republic of Iran. vol 31. 2019-11-20. PMID:29951404. |
probiotics improve insulin resistance status in an experimental model of alzheimer's disease. |
2019-11-20 |
2023-08-13 |
Not clear |
| Ji Yeon Chung, Hyung-Seok Kim, Juhyun Son. Correction to: Iron metabolism in diabetes-induced Alzheimer's disease: a focus on insulin resistance in the brain. Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine. vol 31. issue 6. 2019-11-20. PMID:30225625. |
correction to: iron metabolism in diabetes-induced alzheimer's disease: a focus on insulin resistance in the brain. |
2019-11-20 |
2023-08-13 |
Not clear |
| Soren Hayrabedyan, Krassimira Todorova, Marialuigia Spinelli, Eytan R Barnea, Martin Muelle. The core sequence of PIF competes for insulin/amyloid β in insulin degrading enzyme: potential treatment for Alzheimer's disease. Oncotarget. vol 9. issue 74. 2019-11-20. PMID:30338033. |
the core sequence of pif competes for insulin/amyloid β in insulin degrading enzyme: potential treatment for alzheimer's disease. |
2019-11-20 |
2023-08-13 |
Not clear |
| Gifty M Jojo, Gowthamarajan Kuppusamy, Anindita De, V V S Narayan Reddy Karr. Formulation and optimization of intranasal nanolipid carriers of pioglitazone for the repurposing in Alzheimer's disease using Box-Behnken design. Drug development and industrial pharmacy. vol 45. issue 7. 2019-11-19. PMID:30922126. |
growing evidence suggest that alzheimer's disease (ad), the most common cause of dementia among the elderly is a metabolic disorder associated with impaired brain insulin signaling. |
2019-11-19 |
2023-08-13 |
Not clear |
| Galit Weinstein, Kendra L Davis-Plourde, Sarah Conner, Jayandra J Himali, Alexa S Beiser, Anne Lee, Andreea M Rawlings, Sanaz Sedaghat, Jie Ding, Erin Moshier, Cornelia M van Duijn, Michal S Beeri, Elizabeth Selvin, M Arfan Ikram, Lenore J Launer, Mary N Haan, Sudha Seshadr. Association of metformin, sulfonylurea and insulin use with brain structure and function and risk of dementia and Alzheimer's disease: Pooled analysis from 5 cohorts. PloS one. vol 14. issue 2. 2019-11-18. PMID:30768625. |
association of metformin, sulfonylurea and insulin use with brain structure and function and risk of dementia and alzheimer's disease: pooled analysis from 5 cohorts. |
2019-11-18 |
2023-08-13 |
Not clear |
| Sanaz Nasoohi, Kehkashan Parveen, Tauheed Ishra. Metabolic Syndrome, Brain Insulin Resistance, and Alzheimer's Disease: Thioredoxin Interacting Protein (TXNIP) and Inflammasome as Core Amplifiers. Journal of Alzheimer's disease : JAD. vol 66. issue 3. 2019-11-14. PMID:30372683. |
metabolic syndrome, brain insulin resistance, and alzheimer's disease: thioredoxin interacting protein (txnip) and inflammasome as core amplifiers. |
2019-11-14 |
2023-08-13 |
Not clear |
| Sanaz Nasoohi, Kehkashan Parveen, Tauheed Ishra. Metabolic Syndrome, Brain Insulin Resistance, and Alzheimer's Disease: Thioredoxin Interacting Protein (TXNIP) and Inflammasome as Core Amplifiers. Journal of Alzheimer's disease : JAD. vol 66. issue 3. 2019-11-14. PMID:30372683. |
empirical evidence indicates a strong association between insulin resistance and pathological alterations related to alzheimer's disease (ad) in different cerebral regions. |
2019-11-14 |
2023-08-13 |
Not clear |
| Sho-Ichi Yamagishi, Takanori Matsu. Therapeutic Potential of DNA-aptamers Raised Against AGE-RAGE Axis in Diabetes-related Complications. Current pharmaceutical design. vol 24. issue 24. 2019-10-28. PMID:30156152. |
accumulating evidence has indicated that formation and accumulation of advanced glycation end products (ages) progress under diabetic conditions, thereby contributing to the development and progression of various diabetes- and aging-related disorders, such as diabetic nephropathy, diabetic retinopathy, atherosclerotic cardiovascular disease, insulin resistance, cancer growth and metastasis, osteoporosis, and alzheimer's disease. |
2019-10-28 |
2023-08-13 |
Not clear |
| Rui Lai, Wei-Jen Tang, Hui L. Catalytic Mechanism of Amyloid-β Peptide Degradation by Insulin Degrading Enzyme: Insights from Quantum Mechanics and Molecular Mechanics Style Møller-Plesset Second Order Perturbation Theory Calculation. Journal of chemical information and modeling. vol 58. issue 9. 2019-10-21. PMID:30133282. |
insulin degrading enzyme (ide), a metalloprotease that degrades amyloid-β (aβ) peptides and insulin, is associated with alzheimer's disease and diabetes. |
2019-10-21 |
2023-08-13 |
human |
| Katsura Takano, Keisuke Koarashi, Kenji Kawabe, Masanori Itakura, Hidemitsu Nakajima, Mitsuaki Moriyama, Yoichi Nakamur. Insulin expression in cultured astrocytes and the decrease by amyloid β. Neurochemistry international. vol 119. 2019-09-30. PMID:29108865. |
insulin resistance in brain has been reported in alzheimer's diseases (ad). |
2019-09-30 |
2023-08-13 |
rat |
| Steven E Arnold, Zoe Arvanitakis, Shannon L Macauley-Rambach, Aaron M Koenig, Hoau-Yan Wang, Rexford S Ahima, Suzanne Craft, Sam Gandy, Christoph Buettner, Luke E Stoeckel, David M Holtzman, David M Natha. Brain insulin resistance in type 2 diabetes and Alzheimer disease: concepts and conundrums. Nature reviews. Neurology. vol 14. issue 3. 2019-08-27. PMID:29377010. |
brain insulin resistance in type 2 diabetes and alzheimer disease: concepts and conundrums. |
2019-08-27 |
2023-08-13 |
Not clear |
| Konstantin Bloch, Irit Gil-Ad, Alexey Vanichkin, Shay Henry Hornfeld, Michal Taler, Shira Dar, Dmitry Azarov, Pnina Vardi, Abraham Weizma. Intracranial Transplantation of Pancreatic Islets Attenuates Cognitive and Peripheral Metabolic Dysfunctions in a Rat Model of Sporadic Alzheimer's Disease. Journal of Alzheimer's disease : JAD. vol 65. issue 4. 2019-08-26. PMID:30175977. |
alzheimer's disease (ad) is often associated with brain insulin resistance and peripheral metabolic dysfunctions. |
2019-08-26 |
2023-08-13 |
rat |