| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| D J Heal, S L Smith, R S Kulkarni, H L Rowle. New perspectives from microdialysis studies in freely-moving, spontaneously hypertensive rats on the pharmacology of drugs for the treatment of ADHD. Pharmacology, biochemistry, and behavior. vol 90. issue 2. 2008-08-12. PMID:18456311. |
in this review, these three topics are brought together to explore the contribution of in vivo microdialysis studies in spontaneously hypertensive (sh) rats to our understanding of the neurochemical deficits in this rat strain and the actions of adhd drugs on catecholaminergic function in the prefrontocortex (pfc), striatum and nucleus accumbens. |
2008-08-12 |
2023-08-12 |
rat |
| Avis R Brennan, Amy F T Arnste. Neuronal mechanisms underlying attention deficit hyperactivity disorder: the influence of arousal on prefrontal cortical function. Annals of the New York Academy of Sciences. vol 1129. 2008-07-18. PMID:18591484. |
neuropsychological and imaging studies indicate that attention deficit hyperactivity disorder (adhd) is associated with alterations in prefrontal cortex (pfc) and its connections to striatum and cerebellum. |
2008-07-18 |
2023-08-12 |
monkey |
| Avis R Brennan, Amy F T Arnste. Neuronal mechanisms underlying attention deficit hyperactivity disorder: the influence of arousal on prefrontal cortical function. Annals of the New York Academy of Sciences. vol 1129. 2008-07-18. PMID:18591484. |
alpha2a-adrenoceptor stimulation strengthens the functional connectivity of pfc networks, while blockade of alpha2 receptors in the monkey pfc recreates the symptoms of adhd, resulting in impaired working memory, increased impulsivity, and locomotor hyperactivity. |
2008-07-18 |
2023-08-12 |
monkey |
| Li-Li Liu, Jie Yang, Ge-Fei Lei, Gui-Ju Wang, Yu-Wei Wang, Ruo-Peng Su. Atomoxetine increases histamine release and improves learning deficits in an animal model of attention-deficit hyperactivity disorder: the spontaneously hypertensive rat. Basic & clinical pharmacology & toxicology. vol 102. issue 6. 2008-06-12. PMID:18346050. |
our data confirmed that atomoxetine increases extracellular levels of histamine in the prefrontal cortex, a brain region that is implicated in the pathophysiology of adhd. |
2008-06-12 |
2023-08-12 |
rat |
| K M Kantak, T Singh, K A Kerstetter, K A Dembro, M M Mutebi, R C Harvey, C F Deschepper, L P Dwoski. Advancing the spontaneous hypertensive rat model of attention deficit/hyperactivity disorder. Behavioral neuroscience. vol 122. issue 2. 2008-06-03. PMID:18410173. |
to advance the spontaneous hypertensive rat (shr) model of attention deficit/hyperactivity disorder (adhd), experiments examined the shr in tasks recognized to assess functioning of the prefrontal cortex or dorsal striatal. |
2008-06-03 |
2023-08-12 |
rat |
| Chao-Zhe Zhu, Yu-Feng Zang, Qing-Jiu Cao, Chao-Gan Yan, Yong He, Tian-Zi Jiang, Man-Qiu Sui, Yu-Feng Wan. Fisher discriminative analysis of resting-state brain function for attention-deficit/hyperactivity disorder. NeuroImage. vol 40. issue 1. 2008-04-23. PMID:18191584. |
moreover, some highly discriminative brain regions, like the prefrontal cortex and anterior cingulate cortex, well confirmed the previous findings on adhd. |
2008-04-23 |
2023-08-12 |
Not clear |
| Joel Nigg, Molly Nikolas, Karen Friderici, Leeyoung Park, Robert A Zucke. Genotype and neuropsychological response inhibition as resilience promoters for attention-deficit/hyperactivity disorder, oppositional defiant disorder, and conduct disorder under conditions of psychosocial adversity. Development and psychopathology. vol 19. issue 3. 2008-01-18. PMID:17705902. |
results illustrate potential neurobiological protective factors related to development of prefrontal cortex that may enable children to avoid developing adhd and cd in the presence of psychosocial adversity. |
2008-01-18 |
2023-08-12 |
Not clear |
| Xiaobo Li, Jiefeng Jiang, Wanlin Zhu, Chunshui Yu, Manqiu Sui, Yufeng Wang, Tianzi Jian. Asymmetry of prefrontal cortical convolution complexity in males with attention-deficit/hyperactivity disorder using fractal information dimension. Brain & development. vol 29. issue 10. 2008-01-09. PMID:17573219. |
prefrontal cortex, known to be a crucial region for the function of attention, is generally thought to be largely associated with the pathogenesis of attention-deficit hyperactivity disorder (adhd). |
2008-01-09 |
2023-08-12 |
Not clear |
| Amy F Arnsten, Lawrence Scahill, Robert L Findlin. alpha2-Adrenergic receptor agonists for the treatment of attention-deficit/hyperactivity disorder: emerging concepts from new data. Journal of child and adolescent psychopharmacology. vol 17. issue 4. 2007-11-13. PMID:17822336. |
the following provides a brief review of this field, explaining how compounds like guanfacine and the traditional stimulant medications can reduce the core symptoms of adhd by optimizing the neurochemical environment in the prefrontal cortex (pfc). |
2007-11-13 |
2023-08-12 |
Not clear |
| Margaret A Sheridan, Stephen Hinshaw, Mark D'Esposit. Efficiency of the prefrontal cortex during working memory in attention-deficit/hyperactivity disorder. Journal of the American Academy of Child and Adolescent Psychiatry. vol 46. issue 10. 2007-11-08. PMID:17885578. |
previous research has demonstrated that during task conditions requiring an increase in inhibitory function or working memory, children and adults with attention-deficit/hyperactivity disorder (adhd) exhibit greater and more varied prefrontal cortical (pfc) activation compared to age-matched control participants. |
2007-11-08 |
2023-08-12 |
human |
| R Rodriguez-Jimenez, C Avila, M A Jimenez-Arriero, G Ponce, R Monasor, M Jimenez, M Aragües, J Hoenicka, G Rubio, T Palom. Impulsivity and sustained attention in pathological gamblers: influence of childhood ADHD history. Journal of gambling studies. vol 22. issue 4. 2007-11-01. PMID:16912931. |
our results suggest a possible selective implication of the prefrontal cortex in pg, which would be especially evident in those with a childhood history of adhd. |
2007-11-01 |
2023-08-12 |
Not clear |
| Augusto Pasini, Claudio Paloscia, Riccardo Alessandrelli, Maria Cristina Porfirio, Paolo Curatol. Attention and executive functions profile in drug naive ADHD subtypes. Brain & development. vol 29. issue 7. 2007-10-10. PMID:17207595. |
since right prefrontal cortex seems to be crucial in controlling response inhibition, while left dorsolateral prefrontal cortex seems important in modulating divided attention, these areas are deputated to be involved in the pathogenesis of neuropsychological deficits in adhd subtypes. |
2007-10-10 |
2023-08-12 |
human |
| Katherine A Johnson, Ian H Robertson, Simon P Kelly, Timothy J Silk, Edwina Barry, Aoife Dáibhis, Amy Watchorn, Michelle Keavey, Michael Fitzgerald, Louise Gallagher, Michael Gill, Mark A Bellgrov. Dissociation in performance of children with ADHD and high-functioning autism on a task of sustained attention. Neuropsychologia. vol 45. issue 10. 2007-07-24. PMID:17433378. |
these data imply involvement of fronto-parietal attentional networks and sub-cortical arousal systems in the pathology of adhd and prefrontal cortex dysfunction in children with hfa. |
2007-07-24 |
2023-08-12 |
Not clear |
| Benjamin Charles Campbell, Dan Eisenber. Obesity, attention deficit-hyperactivity disorder and the dopaminergic reward system. Collegium antropologicum. vol 31. issue 1. 2007-07-20. PMID:17600916. |
detailed consideration suggests that dopaminergic changes in the prefrontal cortex among individuals with the adhd subtype attention deficit disorder (add) may increase their risk for obesity. |
2007-07-20 |
2023-08-12 |
Not clear |
| Marc Schneider, Wolfgang Retz, Andrew Coogan, Johannes Thome, Michael Rösle. Anatomical and functional brain imaging in adult attention-deficit/hyperactivity disorder (ADHD)--a neurological view. European archives of psychiatry and clinical neuroscience. vol 256 Suppl 1. 2007-06-27. PMID:16977550. |
the core findings in adhd imaging are alterations in the architecture and function of prefrontal cortex and cerebellum. |
2007-06-27 |
2023-08-12 |
Not clear |
| George Bush, Paul J Whalen, Lisa M Shin, Scott L Rauc. The counting Stroop: a cognitive interference task. Nature protocols. vol 1. issue 1. 2007-06-21. PMID:17406237. |
initially designed as a functional magnetic resonance imaging (fmri) task for identifying brain regions subserving cognition and attention (dorsal anterior midcingulate cortex (damcc) and dorsolateral prefrontal cortex (dlpfc)), it has been used to study cognition in healthy volunteers and to identify functional brain abnormalities in neuropsychiatric disorders, such as attention deficit hyperactivity disorder (adhd). |
2007-06-21 |
2023-08-12 |
human |
| Neil Easton, Fiona Marshall, Kevin Fone, Charles Marsde. Atomoxetine produces changes in cortico-basal thalamic loop circuits: assessed by phMRI BOLD contrast. Neuropharmacology. vol 52. issue 3. 2007-05-01. PMID:17140608. |
although positive bold changes in the prefrontal cortex were limited to the ventral orbital cortex this is an area associated with behavioral control and may be of relevance to the use of the drug in adhd. |
2007-05-01 |
2023-08-12 |
rat |
| Weldon E Horner, David E Johnson, Anne W Schmidt, Hans Rollem. Methylphenidate and atomoxetine increase histamine release in rat prefrontal cortex. European journal of pharmacology. vol 558. issue 1-3. 2007-04-04. PMID:17198700. |
using microdialysis in rat prefrontal cortex, we found that 1 mg/kg of the stimulant methylphenidate and the non-stimulant atomoxetine, two widely used treatments for attention deficit/hyperactivity disorder (adhd), produce robust increases in the extracellular levels of histamine, which plays a key role in attention, learning and memory. |
2007-04-04 |
2023-08-12 |
rat |
| Jeffrey A Stanley, Heidi Kipp, Erika Greisenegger, Frank P MacMaster, K Panchalingam, Jay W Pettegrew, Matcheri S Keshavan, Oscar G Bukstei. Regionally specific alterations in membrane phospholipids in children with ADHD: An in vivo 31P spectroscopy study. Psychiatry research. vol 148. issue 2-3. 2007-02-12. PMID:17095197. |
this multi-voxel, phosphorus magnetic resonance spectroscopy ((31)p mrs) study examined the prefrontal cortex (pfc), basal ganglia (bg) and superior temporal (st) region in 10 children with attention-deficit/hyperactivity disorder (adhd) and 15 healthy controls. |
2007-02-12 |
2023-08-12 |
Not clear |
| Jeffrey A Stanley, Heidi Kipp, Erika Greisenegger, Frank P MacMaster, K Panchalingam, Jay W Pettegrew, Matcheri S Keshavan, Oscar G Bukstei. Regionally specific alterations in membrane phospholipids in children with ADHD: An in vivo 31P spectroscopy study. Psychiatry research. vol 148. issue 2-3. 2007-02-12. PMID:17095197. |
adhd patients had lower pfc and bg phosphomonoester (pme) levels compared to healthy children. |
2007-02-12 |
2023-08-12 |
Not clear |