| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| L Delgado, E R Parra, V L Capelozz. Apoptosis and extracellular matrix remodelling in human silicosis. Histopathology. vol 49. issue 3. 2006-10-25. PMID:16918975. |
apoptosis and extracellular matrix remodelling in human silicosis. |
2006-10-25 |
2023-08-12 |
human |
| Mala R Chinoy, Shane A Mille. Relevance of tenascin-C and matrix metalloproteinases in vascular abnormalities in murine hypoplastic lungs. Biology of the neonate. vol 90. issue 3. 2006-10-24. PMID:16699260. |
tenascin-c (tn-c), an extracellular matrix glycoprotein, is crucial to cell-migration, proliferation, apoptosis and remodeling of tissues, with a potential role in pathobiology of pulmonary hypertension. |
2006-10-24 |
2023-08-12 |
Not clear |
| Julie Rice, Donald L Courter, Cecilia M Giachelli, Marta Scaten. Molecular mediators of alphavbeta3-induced endothelial cell survival. Journal of vascular research. vol 43. issue 5. 2006-10-24. PMID:16888388. |
the alphavbeta3 integrin interaction with the extracellular matrix (ecm) plays an essential role in inhibiting apoptosis in endothelial cells. |
2006-10-24 |
2023-08-12 |
rat |
| Ki-Kyung Jung, Xu-Wen Liu, Rosemarie Chirco, Rafael Fridman, Hyeong-Reh Choi Ki. Identification of CD63 as a tissue inhibitor of metalloproteinase-1 interacting cell surface protein. The EMBO journal. vol 25. issue 17. 2006-10-24. PMID:16917503. |
while mcf10a cells within a three-dimensional (3d) matrigel matrix form polarized acinar-like structures, timp-1 overexpression disrupted breast epithelial cell polarization and inhibited caspase-mediated apoptosis in centrally located cells, necessary for the formation and maintenance of the hollow acinar-like structures. |
2006-10-24 |
2023-08-12 |
human |
| Ki-Kyung Jung, Xu-Wen Liu, Rosemarie Chirco, Rafael Fridman, Hyeong-Reh Choi Ki. Identification of CD63 as a tissue inhibitor of metalloproteinase-1 interacting cell surface protein. The EMBO journal. vol 25. issue 17. 2006-10-24. PMID:16917503. |
cd63 downregulation also restored polarization and apoptosis of timp-1 overexpressing mcf10a cells within a 3d-matrigel matrix. |
2006-10-24 |
2023-08-12 |
human |
| Sandra Cottet, Lydia Michaut, Gaëlle Boisset, Ulrich Schlecht, Walter Gehring, Daniel F Schordere. Biological characterization of gene response in Rpe65-/- mouse model of Leber's congenital amaurosis during progression of the disease. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 20. issue 12. 2006-10-20. PMID:17012256. |
microarray analysis demonstrates altered expression of genes involved in phototransduction, apoptosis regulation, cytoskeleton organization, and extracellular matrix (ecm) constituents. |
2006-10-20 |
2023-08-12 |
mouse |
| Carsten Bergmann, Valeska Frank, Fabian Küpper, Dirk Kamitz, Jens Hanten, Peter Berges, Silke Mager, Markus Moser, Jutta Kirfel, Reinhard Büttner, Jan Senderek, Klaus Zerre. Diagnosis, pathogenesis, and treatment prospects in cystic kidney disease. Molecular diagnosis & therapy. vol 10. issue 3. 2006-10-16. PMID:16771602. |
recent findings have proven the cystogenic process to be compatible with cellular dedifferentiation, i. e. increased apoptosis and proliferation rates, altered protein sorting and secretory characteristics, as well as disorganization of the extracellular matrix. |
2006-10-16 |
2023-08-12 |
Not clear |
| Maike Gallwitz, Jenny M Reimer, Lars Hellma. Expansion of the mast cell chymase locus over the past 200 million years of mammalian evolution. Immunogenetics. vol 58. issue 8. 2006-10-05. PMID:16807745. |
functionally, these proteases are involved, e.g., in the induction of apoptosis, the recruitment of inflammatory cells, and the remodeling of extra-cellular matrix. |
2006-10-05 |
2023-08-12 |
cattle |
| Claudia María Valverde, Teresa Macarulla, Esther Casado, Francisco Javier Ramos, Erika Martinelli, Josep Taberner. Novel targets in gastric and esophageal cancer. Critical reviews in oncology/hematology. vol 59. issue 2. 2006-10-05. PMID:16829119. |
in this review we describe the current status of targeted therapies in the treatment of ec and gc, including egfr inhibitors, antiangiogenic agents, cell cycle inhibitors, apoptosis promoters and matrix metalloproteinases inhibitors. |
2006-10-05 |
2023-08-12 |
Not clear |
| Farshid Saadat, Mohammad Reza Khorramizadeh, Abbas Mirshafie. Chemoprevention by pyrimethamine. Immunopharmacology and immunotoxicology. vol 27. issue 2. 2006-09-28. PMID:16114507. |
the fibrosarcoma (wehi-164) cell line was used for evaluating cytotoxicity, matrix metalloproteinase 2 (mmp-2) activity, and apoptosis. |
2006-09-28 |
2023-08-12 |
Not clear |
| Zhiwei Wang, Radha Sengupta, Sanjeev Banerjee, Yiwei Li, Yuxiang Zhang, K M Wahidur Rahman, Amro Aboukameel, Ramzi Mohammad, Adhip P N Majumdar, James L Abbruzzese, Fazlul H Sarka. Epidermal growth factor receptor-related protein inhibits cell growth and invasion in pancreatic cancer. Cancer research. vol 66. issue 15. 2006-09-28. PMID:16885366. |
this was accompanied by increased apoptosis and concomitant attenuation of notch-1 and nf-kappab and down-regulation of nf-kappab downstream genes, such as matrix metalloproteinase-9 and vascular endothelial growth factor, resulting in the inhibition of pancreatic cancer cell invasion through the matrigel. |
2006-09-28 |
2023-08-12 |
human |
| Eric W Olle, Xiaodan Ren, Shannon D McClintock, Roscoe L Warner, Michael P Deogracias, Kent J Johnson, Lisa M Collett. Matrix metalloproteinase-9 is an important factor in hepatic regeneration after partial hepatectomy in mice. Hepatology (Baltimore, Md.). vol 44. issue 3. 2006-09-28. PMID:16941692. |
partial hepatectomy triggers hepatocyte proliferation, hepatic matrix remodeling, and hepatocyte apoptosis, all of which are important processes in the regenerating liver. |
2006-09-28 |
2023-08-12 |
mouse |
| Olivier Morel, Florence Toti, Babé Bakouboula, Lélia Grunebaum, Jean-Marie Freyssine. Procoagulant microparticles: 'criminal partners' in atherothrombosis and deleterious cellular exchanges. Pathophysiology of haemostasis and thrombosis. vol 35. issue 1-2. 2006-09-22. PMID:16855341. |
besides this procoagulant potential, trapped mp could contribute to plaque vulnerability through multiple pathways including angiogenesis, extracellular matrix proteolysis, recruitment of inflammatory cells, smooth muscle cell and endothelial apoptosis. |
2006-09-22 |
2023-08-12 |
human |
| Livia S Machado, Anna Kozak, Adviye Ergul, David C Hess, Cesario V Borlongan, Susan C Faga. Delayed minocycline inhibits ischemia-activated matrix metalloproteinases 2 and 9 after experimental stroke. BMC neuroscience. vol 7. 2006-09-20. PMID:16846501. |
minocycline inhibits inflammation, apoptosis and extracellular matrix degradation. |
2006-09-20 |
2023-08-12 |
rat |
| Hiroyuki Tsutsu. Mitochondrial oxidative stress and heart failure. Internal medicine (Tokyo, Japan). vol 45. issue 13. 2006-09-15. PMID:16880705. |
reactive oxygen species induce myocyte hypertrophy, apoptosis, and interstitial fibrosis by activating matrix metalloproteinases. |
2006-09-15 |
2023-08-12 |
Not clear |
| S Viappiani, M Sariahmetoglu, R Schul. The role of matrix metalloproteinase inhibitors in ischemia-reperfusion injury in the liver. Current pharmaceutical design. vol 12. issue 23. 2006-09-15. PMID:16918422. |
liver ischemia-reperfusion injury is characterized by cell necrosis and apoptosis and by profound modifications in the extracellular matrix (ecm). |
2006-09-15 |
2023-08-12 |
Not clear |
| S Viappiani, M Sariahmetoglu, R Schul. The role of matrix metalloproteinase inhibitors in ischemia-reperfusion injury in the liver. Current pharmaceutical design. vol 12. issue 23. 2006-09-15. PMID:16918422. |
several experimental models of liver ischemia-reperfusion injury have demonstrated protective effects of mmp inhibitors in terms of cell necrosis, apoptosis and rearrangement of the extracellular matrix. |
2006-09-15 |
2023-08-12 |
Not clear |
| Roland D Chapurlat, Pierre D Delma. Drug insight: Bisphosphonates for postmenopausal osteoporosis. Nature clinical practice. Endocrinology & metabolism. vol 2. issue 4. 2006-09-15. PMID:16932286. |
when embedded in bone matrix, bisphosphonates are taken up by osteoclasts engaged in bone resorption, leading--mainly by inhibition of farnesyl diphosphate synthase, a key enzyme of the mevalonate pathway--to osteoclast apoptosis. |
2006-09-15 |
2023-08-12 |
Not clear |
| K Boisvert-Adamo, A E Apli. B-RAF and PI-3 kinase signaling protect melanoma cells from anoikis. Oncogene. vol 25. issue 35. 2006-09-13. PMID:16547495. |
a hallmark feature of cancer is resistance to anoikis, apoptosis induced when cells either lose contact with or encounter an inappropriate extracellular matrix. |
2006-09-13 |
2023-08-12 |
Not clear |
| Jie Shen, Darryl O'Brien, Yi X. Matrix metalloproteinase-2 contributes to tumor necrosis factor alpha induced apoptosis in cultured rat cardiac myocytes. Biochemical and biophysical research communications. vol 347. issue 4. 2006-09-13. PMID:16857167. |
matrix metalloproteinase-2 contributes to tumor necrosis factor alpha induced apoptosis in cultured rat cardiac myocytes. |
2006-09-13 |
2023-08-12 |
human |