| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| G Oktem, S Vatansever, S Ayla, A Uysal, S Aktas, B Karabulut, A Bili. Effect of apoptosis and response of extracellular matrix proteins after chemotherapy application on human breast cancer cell spheroids. Oncology reports. vol 15. issue 2. 2006-06-01. PMID:16391851. |
in this study, we examined the effect of apoptosis and proliferation of cells on the human breast cancer cell line, mcf-7, by using p53, bcl-2 and ki67 gene expression, and the tendency to metastasis with extracellular matrix proteins, laminin and type iv collagen after chemotherapy in the spheroid model. |
2006-06-01 |
2023-08-12 |
human |
| Randal A Wolff, Rita L Malinowski, Nicholas S Heaton, Debra A Hullett, John R Hoc. Transforming growth factor-beta1 antisense treatment of rat vein grafts reduces the accumulation of collagen and increases the accumulation of h-caldesmon. Journal of vascular surgery. vol 43. issue 5. 2006-05-30. PMID:16678700. |
transforming growth factor beta-1 (tgf-beta1) is a pleiotropic cytokine known to have powerful effects on cell growth, apoptosis, cell differentiation, and extracellular matrix synthesis. |
2006-05-30 |
2023-08-12 |
rat |
| Hsiu-Wen Chan, Nicola J Smith, Ross D Hannan, Walter G Thoma. Tackling the EGFR in pathological tissue remodelling. Pulmonary pharmacology & therapeutics. vol 19. issue 1. 2006-05-11. PMID:15979363. |
tissue remodelling is an adaptive physiological event initiated by physical and/or hormonal stimuli and characterised by extracellular matrix modifications, inflammation, cellular hypertrophy, proliferation and/or apoptosis. |
2006-05-11 |
2023-08-12 |
Not clear |
| L F A Huitema, A B Vaandrager, P R van Weeren, A Barneveld, J B Helms, C H A van de Les. The nitric oxide donor sodium nitroprusside inhibits mineralization in ATDC5 cells. Calcified tissue international. vol 78. issue 3. 2006-05-11. PMID:16523220. |
these findings indicate that snp can specifically inhibit matrix mineralization via a cgmp-independent pathway and that the effect is not mediated by inhibition of phosphate transport or apoptosis. |
2006-05-11 |
2023-08-12 |
Not clear |
| Soo Jung Cho, Min Jong Kang, Robert J Homer, Hye Ryun Kang, Xuchen Zhang, Patty J Lee, Jack A Elias, Chun Geun Le. Role of early growth response-1 (Egr-1) in interleukin-13-induced inflammation and remodeling. The Journal of biological chemistry. vol 281. issue 12. 2006-05-10. PMID:16439363. |
lastly, they provide insights into the mechanisms of these processes by demonstrating that il-13 stimulates select cc and cxc chemokines (mip-1alpha/ccl-3, mip-1beta/ccl-4, mip-2/cxcl2/3, mcp-1/ccl-2, mcp-2/ccl-8, mcp-3/ccl-7, mcp-5/ccl-12, kc/cxcl-1, and lix/cxcl-5), matrix metalloproteinase-9, tissue inhibitor of metalloproteinase-1, and apoptosis regulators (caspase-3, -6, -8, and -9 and bax) and activates transforming growth factor-beta1 and pulmonary caspases via egr-1-dependent pathways. |
2006-05-10 |
2023-08-12 |
mouse |
| Helen Kalirai, Moshe Phillip, Lars Savendahl, Jan-M Wi. The Fifth European Growth Plate Working Group Symposium. 21st September 2005, Lyon, France. Journal of pediatric endocrinology & metabolism : JPEM. vol 19. issue 2. 2006-05-05. PMID:16562594. |
the result of these events is calcification of the matrix, chondrocyte apoptosis, and the completion of endochondral bone formation. |
2006-05-05 |
2023-08-12 |
human |
| Shufang Wu, Yuji Yoshiko, Francesco De Luc. Stanniocalcin 1 acts as a paracrine regulator of growth plate chondrogenesis. The Journal of biological chemistry. vol 281. issue 8. 2006-05-04. PMID:16377640. |
in cultured chondrocytes, rhstc increased phosphate uptake, reduced chondrocyte proliferation and matrix synthesis, and induced apoptosis. |
2006-05-04 |
2023-08-12 |
mouse |
| Shufang Wu, Yuji Yoshiko, Francesco De Luc. Stanniocalcin 1 acts as a paracrine regulator of growth plate chondrogenesis. The Journal of biological chemistry. vol 281. issue 8. 2006-05-04. PMID:16377640. |
such growth inhibition, likely mediated by an increased chondrocyte phosphate uptake, results from suppressed chondrocyte proliferation, hypertrophy/differentiation, and matrix synthesis and by increased apoptosis. |
2006-05-04 |
2023-08-12 |
mouse |
| Shu Nakamura, Yuji Arai, Kenji A Takahashi, Ryu Terauchi, Suzuyo Ohashi, Osam Mazda, Jiro Imanishi, Atsuo Inoue, Hitoshi Tonomura, Toshikazu Kub. Hydrostatic pressure induces apoptosis of chondrocytes cultured in alginate beads. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. vol 24. issue 4. 2006-05-04. PMID:16514637. |
excessively strong hp could evoke apoptosis when the extracellular matrix did not accumulate around the chondrocytes. |
2006-05-04 |
2023-08-12 |
rabbit |
| Jeremias Wohlschlaeger, Klaus J Schmitz, Christof Schmid, Kurt W Schmid, Petra Keul, Atsushi Takeda, Serge Weis, Bodo Levkau, Hideo A Bab. Reverse remodeling following insertion of left ventricular assist devices (LVAD): a review of the morphological and molecular changes. Cardiovascular research. vol 68. issue 3. 2006-05-03. PMID:16024006. |
aside from describing the morphological changes, this review focuses on the roles of signal transduction, transcriptional regulation, apoptosis, stress proteins, matrix remodeling, and neurohormonal signaling in the failing human heart before and after mechanical circulatory support. |
2006-05-03 |
2023-08-12 |
human |
| John R Davies, James H F Rudd, Peter L Weissberg, Jagat Narul. Radionuclide imaging for the detection of inflammation in vulnerable plaques. Journal of the American College of Cardiology. vol 47. issue 8 Suppl. 2006-05-01. PMID:16631511. |
tracer compounds capable of assessing macrophage recruitment, foam cell generation, matrix metalloproteinase production, macrophage apoptosis, and macrophage metabolism have been developed and tested in the carotid and peripheral circulation. |
2006-05-01 |
2023-08-12 |
Not clear |
| Toshiaki Monkawa, Jeffrey Pippin, Yoshikage Yo, Jeffrey B Kopp, Charles E Alpers, Stuart J Shanklan. The cyclin-dependent kinase inhibitor p21 limits murine mesangial proliferative glomerulonephritis. Nephron. Experimental nephrology. vol 102. issue 1. 2006-04-27. PMID:16179805. |
mesangial cell (mc) proliferation underlies increased matrix accumulation in glomerulonephritis (gn), and the resolution of mc proliferation occurs largely through apoptosis. |
2006-04-27 |
2023-08-12 |
Not clear |
| Fu-Tong Li. Galectins: novel anti-inflammatory drug targets. Expert opinion on therapeutic targets. vol 6. issue 4. 2006-04-26. PMID:16353421. |
extracellularly, they have the potential to bind to various surface receptors on a variety of cell types as well as extracellular matrix (ecm) proteins, thus causing cell activation or apoptosis, modulating cell adhesion and inducing cell migration. |
2006-04-26 |
2023-08-12 |
Not clear |
| Yatsuki Aratake, Hajime Nomura, Tomio Kotani, Kosuke Marutsuka, Kaoru Kobayashi, Kanji Kuma, Akira Miyauchi, Akihiko Okayama, Kazuo Tamur. Coexistent anaplastic and differentiated thyroid carcinoma: an immunohistochemical study. American journal of clinical pathology. vol 125. issue 3. 2006-04-25. PMID:16613343. |
these findings indicate high proliferative properties, suppression of apoptosis, disruption of cell-cell interaction, and induction of matrix metalloproteinases in the undifferentiated areas. |
2006-04-25 |
2023-08-12 |
Not clear |
| Deepak Kumar, Willa Fung, Robert M Moore, Vishal Pandey, Jennifer Fox, Bradley Stetzer, Joseph M Mansour, Brian M Mercer, Raymond W Redline, John J Moor. Proinflammatory cytokines found in amniotic fluid induce collagen remodeling, apoptosis, and biophysical weakening of cultured human fetal membranes. Biology of reproduction. vol 74. issue 1. 2006-04-17. PMID:16148217. |
we have recently reported that fm weaken, at least in part, because of a developmental process of extracellular matrix remodeling and apoptosis. |
2006-04-17 |
2023-08-12 |
human |
| Deepak Kumar, Willa Fung, Robert M Moore, Vishal Pandey, Jennifer Fox, Bradley Stetzer, Joseph M Mansour, Brian M Mercer, Raymond W Redline, John J Moor. Proinflammatory cytokines found in amniotic fluid induce collagen remodeling, apoptosis, and biophysical weakening of cultured human fetal membranes. Biology of reproduction. vol 74. issue 1. 2006-04-17. PMID:16148217. |
matrix metalloproteinase 9 (mmp9) protein increased, tissue inhibitor of matrix metalloproteinase 3 (timp3) protein decreased, and poly (adp-ribose) polymerase (parp1) cleavage increased with increasing tnf or il1b doses (all p < 0.05), suggesting collagen remodeling and apoptosis. |
2006-04-17 |
2023-08-12 |
human |
| Dimcho Bachvarov, Magdalena Bachvarova, Rainelli Koumangaye, Julie Klein, João Bosco Pesquero, Eric Neau, Michael Bader, Joost P Schanstra, Jean Loup Bascand. Renal gene expression profiling using kinin B1 and B2 receptor knockout mice reveals comparable modulation of functionally related genes. Biological chemistry. vol 387. issue 1. 2006-04-17. PMID:16497160. |
recent data evidenced a role for bk in many other biological processes, such as apoptosis, development, extracellular matrix regulation and angiogenesis. |
2006-04-17 |
2023-08-12 |
mouse |
| Angela M Meyer zum Gottesberge, Heidi Feli. Abnormal basement membrane in the inner ear and the kidney of the Mpv17-/- mouse strain: ultrastructural and immunohistochemical investigations. Histochemistry and cell biology. vol 124. issue 6. 2006-04-13. PMID:16041630. |
these studies explain the cellular responses to missing mpv17-protein, such as accumulation of the extracellular matrix, degeneration, and apoptosis in the inner ear. |
2006-04-13 |
2023-08-12 |
mouse |
| A Haisch, U Marzahn, A Mobasheri, G Schulze-Tanzil, M Shakibae. Development and phenotypic characterization of a high density in vitro model of auricular chondrocytes with applications in reconstructive plastic surgery. Histology and histopathology. vol 21. issue 5. 2006-04-13. PMID:16493577. |
western blotting was used to analyse the expression of cartilage-specific markers, such as collagen type ii and cartilage specific proteoglycan, fibronectin, cell adhesion and signal transduction receptor beta1-integrin, matrix metalloproteinases (mmp-9, mmp-13), cyclo-oxygenase (cox)-2 and the apoptosis commitment marker, activated caspase-3. |
2006-04-13 |
2023-08-12 |
Not clear |
| Guixia Wang, Kashif A Ahmad, Khalil Ahme. Modulation of death receptor-mediated apoptosis by CK2. Molecular and cellular biochemistry. vol 274. issue 1-2. 2006-04-10. PMID:16342415. |
we originally documented that removal of survival or growth stimuli resulted in rapid loss of ck2 from the nuclear matrix and chromatin which preceded induction of apoptosis. |
2006-04-10 |
2023-08-12 |
Not clear |