| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ute Oltmanns, Maria B Sukkar, Shaoping Xie, Matthias John, K Fan Chun. Induction of human airway smooth muscle apoptosis by neutrophils and neutrophil elastase. American journal of respiratory cell and molecular biology. vol 32. issue 4. 2005-04-28. PMID:15653931. |
the local release of proteases from neutrophils present in airway smooth muscle cells may lead to hasmc apoptosis as a result of matrix degradation and loss of cell attachment. |
2005-04-28 |
2023-08-12 |
human |
| Asha Manohar, Swati Ghosh Shome, John Lamar, Lee Stirling, Vandana Iyer, Kevin Pumiglia, C Michael DiPersi. Alpha 3 beta 1 integrin promotes keratinocyte cell survival through activation of a MEK/ERK signaling pathway. Journal of cell science. vol 117. issue Pt 18. 2005-04-26. PMID:15280429. |
inadequate or inappropriate adhesion of epithelial cells to extracellular matrix leads to a form of apoptosis known as anoikis. |
2005-04-26 |
2023-08-12 |
mouse |
| Asha Manohar, Swati Ghosh Shome, John Lamar, Lee Stirling, Vandana Iyer, Kevin Pumiglia, C Michael DiPersi. Alpha 3 beta 1 integrin promotes keratinocyte cell survival through activation of a MEK/ERK signaling pathway. Journal of cell science. vol 117. issue Pt 18. 2005-04-26. PMID:15280429. |
we show that alpha 3 beta 1-mediated adhesion to laminin-5 extracellular matrix inhibits proteolytic activation of caspase-3 and tunel-staining, both hallmarks of apoptosis. |
2005-04-26 |
2023-08-12 |
mouse |
| Daniel F Gaddy, Douglas S Lyle. Vesicular stomatitis viruses expressing wild-type or mutant M proteins activate apoptosis through distinct pathways. Journal of virology. vol 79. issue 7. 2005-04-26. PMID:15767418. |
the viral matrix (m) protein induces apoptosis via the mitochondrial pathway due to the inhibition of host gene expression. |
2005-04-26 |
2023-08-12 |
Not clear |
| Sheng-Bin Peng, Lei Yan, Xiaoling Xia, Scott A Watkins, Harold B Brooks, Douglas Beight, David K Herron, Michael L Jones, John W Lampe, William T McMillen, Nicholas Mort, J Scott Sawyer, Jonathan M Yinglin. Kinetic characterization of novel pyrazole TGF-beta receptor I kinase inhibitors and their blockade of the epithelial-mesenchymal transition. Biochemistry. vol 44. issue 7. 2005-04-25. PMID:15709742. |
transforming growth factor beta (tgf-beta) signaling pathways regulate a wide variety of cellular processes including cell proliferation, differentiation, extracellular matrix deposition, development, and apoptosis. |
2005-04-25 |
2023-08-12 |
human |
| Donatella Del Bufalo, Daniela Trisciuoglio, Marco Scarsella, Giulia D'Amati, Antonio Candiloro, Angela Iervolino, Carlo Leonetti, Gabriella Zup. Lonidamine causes inhibition of angiogenesis-related endothelial cell functions. Neoplasia (New York, N.Y.). vol 6. issue 5. 2005-04-21. PMID:15548359. |
the viability, migration, invasion, and matrix metalloproteinase production of different tumor cell lines were not affected by low doses of lnd (1-10 microg/ml), whereas 50 microg/ml lnd, which corresponds to the dose used in clinical management of tumors, triggered apoptosis both in endothelial and tumor cells. |
2005-04-21 |
2023-08-12 |
Not clear |
| D R Clemmons, L A Mail. Interaction between insulin-like growth factor-I receptor and alphaVbeta3 integrin linked signaling pathways: cellular responses to changes in multiple signaling inputs. Molecular endocrinology (Baltimore, Md.). vol 19. issue 1. 2005-04-20. PMID:15528274. |
integrins are heterodimeric transmembrane proteins that mediate cell attachment to extracellular matrix, migration, division, and inhibition of apoptosis. |
2005-04-20 |
2023-08-12 |
Not clear |
| Maria R Zocchi, A Pogg. PECAM-1, apoptosis and CD34+ precursors. Leukemia & lymphoma. vol 45. issue 11. 2005-04-18. PMID:15512808. |
apoptosis is a physiological process that controls tissue homeostasis, in combination with survival signals delivered by distinct receptors that bind hormones, growth factors or extracellular matrix components. |
2005-04-18 |
2023-08-12 |
Not clear |
| A Mirshafiey, F Vaezzadeh, M R Khorramizadeh, F Saada. Effect of piroxicam on matrix metalloproteinase 2 and apoptosis. International journal of tissue reactions. vol 26. issue 1-2. 2005-04-18. PMID:15573686. |
effect of piroxicam on matrix metalloproteinase 2 and apoptosis. |
2005-04-18 |
2023-08-12 |
Not clear |
| A Mirshafiey, F Vaezzadeh, M R Khorramizadeh, F Saada. Effect of piroxicam on matrix metalloproteinase 2 and apoptosis. International journal of tissue reactions. vol 26. issue 1-2. 2005-04-18. PMID:15573686. |
we examined the effect of a nonsteroidal anti-inflammatory drug (nsaid), piroxicam, on apoptosis and matrix metalloproteinase 2 (mmp-2) activity compared with diclofenac and dexamethasone. |
2005-04-18 |
2023-08-12 |
Not clear |
| M Wetzel, J Tibbitts, G A Rosenberg, L A Cunningha. Vulnerability of mouse cortical neurons to doxorubicin-induced apoptosis is strain-dependent and is correlated with mRNAs encoding Fas, Fas-Ligand, and metalloproteinases. Apoptosis : an international journal on programmed cell death. vol 9. issue 5. 2005-04-12. PMID:15314293. |
cell surface death receptor-mediated neuronal apoptosis, which is a critical component of neurodegeneration, is modulated by matrix metalloproteinases (mmps) and their tissue inhibitors (timps). |
2005-04-12 |
2023-08-12 |
mouse |
| Sheba Anin Anin, Gill Vince, Siobhan Quenb. Trophoblast invasion. Human fertility (Cambridge, England). vol 7. issue 3. 2005-04-12. PMID:15590570. |
for successful invasion to occur, extravillous trophoblast has to perform a range of functions; transformation of the maternal spiral arteries, tolerate hypoxia, proliferate and die by apoptosis (programmed cell death), differentiate, adhere to and digest the extracellular matrix, move and interact with the maternal immune system. |
2005-04-12 |
2023-08-12 |
Not clear |
| Amy Meyer, Cynthia M van Golen, Madanamohan Boyanapalli, Bhumsoo Kim, Mary E Soules, Eva L Feldma. Integrin-linked kinase complexes with caveolin-1 in human neuroblastoma cells. Biochemistry. vol 44. issue 3. 2005-04-12. PMID:15654749. |
overexpression of ilk leads to altered expression of cell cycle regulators, a decreased level of cell adhesion to the extracellular matrix, a decreased level of apoptosis, in vitro phosphorylation of akt, and tumor formation in nude mice. |
2005-04-12 |
2023-08-12 |
mouse |
| Tina Gröholm, Piet Finckenberg, Eeva Palojoki, Antti Saraste, Tom Bäcklund, Anders Eriksson, Mika Laine, Eero Mervaala, Ilkka Tikkane. Cardioprotective effects of vasopeptidase inhibition vs. angiotensin type 1-receptor blockade in spontaneously hypertensive rats on a high salt diet. Hypertension research : official journal of the Japanese Society of Hypertension. vol 27. issue 8. 2005-04-06. PMID:15492481. |
cardioprotection was associated with prevention of cardiomyocyte apoptosis and inhibition of extracellular matrix formation. |
2005-04-06 |
2023-08-12 |
rat |
| M S Lee, Y K Tu, C C K Chao, S C Chen, C Y Chen, Y S Chan, W L Yeh, S W N Uen. Inhibition of nitric oxide can ameliorate apoptosis and modulate matrix protein gene expression in bacteria infected chondrocytes in vitro. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. vol 23. issue 2. 2005-03-31. PMID:15734260. |
inhibition of nitric oxide can ameliorate apoptosis and modulate matrix protein gene expression in bacteria infected chondrocytes in vitro. |
2005-03-31 |
2023-08-12 |
Not clear |
| M S Lee, Y K Tu, C C K Chao, S C Chen, C Y Chen, Y S Chan, W L Yeh, S W N Uen. Inhibition of nitric oxide can ameliorate apoptosis and modulate matrix protein gene expression in bacteria infected chondrocytes in vitro. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. vol 23. issue 2. 2005-03-31. PMID:15734260. |
the purpose of the study was to test if inhibition of no could ameliorate apoptosis and modulate matrix protein gene expression in bacteria-infected chondrocytes. |
2005-03-31 |
2023-08-12 |
Not clear |
| M S Lee, Y K Tu, C C K Chao, S C Chen, C Y Chen, Y S Chan, W L Yeh, S W N Uen. Inhibition of nitric oxide can ameliorate apoptosis and modulate matrix protein gene expression in bacteria infected chondrocytes in vitro. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. vol 23. issue 2. 2005-03-31. PMID:15734260. |
inhibition of no after the induction of infection could not decrease the extent of apoptosis and modulate matrix protein gene expression. |
2005-03-31 |
2023-08-12 |
Not clear |
| M S Lee, Y K Tu, C C K Chao, S C Chen, C Y Chen, Y S Chan, W L Yeh, S W N Uen. Inhibition of nitric oxide can ameliorate apoptosis and modulate matrix protein gene expression in bacteria infected chondrocytes in vitro. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. vol 23. issue 2. 2005-03-31. PMID:15734260. |
pre-treatment but not post-treatment could ameliorate the extent of apoptosis and reestablish the cartilage matrix protein gene expression. |
2005-03-31 |
2023-08-12 |
Not clear |
| Hiroyuki Tsutsu. Novel pathophysiological insight and treatment strategies for heart failure--lessons from mice and patients--. Circulation journal : official journal of the Japanese Circulation Society. vol 68. issue 12. 2005-03-29. PMID:15564690. |
oxidative stress causes myocyte hypertrophy, apoptosis, and interstitial fibrosis by activating matrix metalloproteinases, all of which result in myocardial remodeling and failure. |
2005-03-29 |
2023-08-12 |
mouse |
| Toshiaki Endo, Tamotsu Kiya, Yoshimitsu Kitajima, Hiroyuki Honnma, Manabu Chida, Takumi Hayashi, Hirofumi Henmi, Kiyohiro Yamazaki, Takuhiro Hayashi, Kengo Manase, Ryuichi Kud. Identical changes in Bax expression, but not Fas ligand expression, occur in structural luteolysis in gonadotropin releasing hormone agonist- and prolactin-treated superovulated rats. Life sciences. vol 76. issue 19. 2005-03-28. PMID:15733931. |
we reported that one of the mechanisms of structural luteolysis induced by prl was tissue remodeling by matrix metalloproteinase (mmp) and also apoptosis in superovulated rats. |
2005-03-28 |
2023-08-12 |
rat |