| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Wei Li, Anna Hellsten, Leif S Jacobsson, Henrik M Blomqvist, Anders G Olsson, Xi-Ming Yua. Alpha-tocopherol and astaxanthin decrease macrophage infiltration, apoptosis and vulnerability in atheroma of hyperlipidaemic rabbits. Journal of molecular and cellular cardiology. vol 37. issue 5. 2005-03-25. PMID:15522274. |
both antioxidants also improved plaque stability and significantly diminished apoptosis, which mainly occurred in macrophages, matrix metalloproteinase three expressions and plaque ruptures. |
2005-03-25 |
2023-08-12 |
Not clear |
| Atsushi Takeda, Haruna Tamano, Yuko Ibuk. Change of zinc uptake under growth arrest and apoptosis. Anticancer research. vol 24. issue 6. 2005-03-22. PMID:15736424. |
when apoptosis was induced in the cells detached from the extracellular matrix under serum-free condition, 65zn uptake by the cells led to apoptosis which was significantly higher than that by the control cells. |
2005-03-22 |
2023-08-12 |
Not clear |
| Jae-Bum Jun, Melanie Kuechle, Junki Min, Seung Cheol Shim, Giok Kim, Vivianne Montenegro, Joseph H Korn, Keith B Elko. Scleroderma fibroblasts demonstrate enhanced activation of Akt (protein kinase B) in situ. The Journal of investigative dermatology. vol 124. issue 2. 2005-03-21. PMID:15675946. |
recent studies suggest that, in addition to activation and hypersecretion of matrix components, fibroblasts from patients with systemic sclerosis (ssc) are relatively resistant to apoptosis. |
2005-03-21 |
2023-08-12 |
Not clear |
| Rosa Serra, Michael R Crowle. TGF-beta in mammary gland development and breast cancer. Breast disease. vol 18. 2005-03-21. PMID:15687689. |
tgf-beta also regulates apoptosis and matrix remodeling during involution at the end of the pregnancy cycle. |
2005-03-21 |
2023-08-12 |
Not clear |
| Frédéric Chiambaretta, Fabienne De Graeve, Gilles Turet, Geoffroy Marceau, Philippe Gain, Bernard Dastugue, Daniéle Rigal, Vincent Sapi. Cell and tissue specific expression of human Krüppel-like transcription factors in human ocular surface. Molecular vision. vol 10. 2005-03-17. PMID:15570219. |
its integrity depends on numerous molecular and cellular processes such as proliferation, differentiation, apoptosis, adhesion, and extracellular matrix homeostasis, whose deregulation can induce ophthalmological pathologies. |
2005-03-17 |
2023-08-12 |
human |
| Xu-Wen Liu, Marcus E Taube, Ki-Kyung Jung, Zhong Dong, Yong J Lee, Stefanie Roshy, Bonnie F Sloane, Rafael Fridman, Hyeong-Reh Choi Ki. Tissue inhibitor of metalloproteinase-1 protects human breast epithelial cells from extrinsic cell death: a potential oncogenic activity of tissue inhibitor of metalloproteinase-1. Cancer research. vol 65. issue 3. 2005-03-14. PMID:15705888. |
timp-1 inhibition of trail-induced apoptosis does not depend on its ability to inhibit matrix metalloproteinases or adam activities and is unrelated to its ability to stabilize active or decoy death receptors. |
2005-03-14 |
2023-08-12 |
human |
| Ramkumar Menon, Stephen J Fortunat. The role of matrix degrading enzymes and apoptosis in rupture of membranes. Journal of the Society for Gynecologic Investigation. vol 11. issue 7. 2005-03-10. PMID:15458739. |
the role of matrix degrading enzymes and apoptosis in rupture of membranes. |
2005-03-10 |
2023-08-12 |
human |
| R Mezencev, A Kohú. [Apoptosis, tumor phenotype and pathogenesis of malignant tumors]. Ceskoslovenska fysiologie. vol 53. issue 2. 2005-03-10. PMID:15709640. |
that results in dysregulation of the cell cycle and apoptosis and in the development of other signs of tumour phenotype (chromosomal instability, disruption of dna repair, disruption of cell-cell communications and interactions between cells and extracellular matrix, suppression of the cell differentiation and replicative senescence, angiogenesis and changes in cell motile activity). |
2005-03-10 |
2023-08-12 |
Not clear |
| Wilfred D Stein, Thomas Litman, Tito Fojo, Susan E Bate. Differential expression of cell adhesion genes: implications for drug resistance. International journal of cancer. vol 113. issue 6. 2005-03-07. PMID:15514970. |
studies that compare cells grown in suspension to similar cells grown attached to one another as aggregates have suggested that it is adhesion to the extracellular matrix of the basal membrane that confers resistance to apoptosis and, hence, resistance to cytotoxins. |
2005-03-07 |
2023-08-12 |
Not clear |
| Toshiaki Takahashi, Ken-Ichi Kitaoka, Yasuhiro Ogawa, Toshihiro Kobayashi, Harumichi Seguchi, Toshikazu Tani, Shoji Yoshid. Lysosomal dysfunction on hydrogen peroxide-induced apoptosis of osteoarthritic chondrocytes. International journal of molecular medicine. vol 14. issue 2. 2005-03-04. PMID:15254765. |
anti-oxidants may have a therapeutic application in the prevention of lysosomal dysfunction to inhibit chondrocyte apoptosis and degradation of the cartilage matrix. |
2005-03-04 |
2023-08-12 |
Not clear |
| Tosikazu Amano, Liezhen Fu, Shelley Sahu, Meghan Markey, Yun-Bo Sh. Substrate specificity of Xenopus matrix metalloproteinase stromelysin-3. International journal of molecular medicine. vol 14. issue 2. 2005-03-04. PMID:15254771. |
the matrix metalloproteinase stromelysin-3 (st3 or mmp11) was initially identified as a breast carcinoma associated protease and has since been shown to be highly expressed in diverse carcinomas and in developmental processes that involve extensive cell death (apoptosis) and tissue remodeling. |
2005-03-04 |
2023-08-12 |
human |
| Jan Pinkas, Stuart S Martin, Philip Lede. Bcl-2-mediated cell survival promotes metastasis of EpH4 betaMEKDD mammary epithelial cells. Molecular cancer research : MCR. vol 2. issue 10. 2005-03-04. PMID:15498929. |
detachment of epithelial cells from the extracellular matrix causes disruption of the actin cytoskeleton and induces apoptosis. |
2005-03-04 |
2023-08-12 |
mouse |
| Chikako Odaka, Masatoshi Tanioka, Takeshi Ito. Matrix metalloproteinase-9 in macrophages induces thymic neovascularization following thymocyte apoptosis. Journal of immunology (Baltimore, Md. : 1950). vol 174. issue 2. 2005-03-03. PMID:15634906. |
matrix metalloproteinase-9 in macrophages induces thymic neovascularization following thymocyte apoptosis. |
2005-03-03 |
2023-08-12 |
mouse |
| Chikako Odaka, Masatoshi Tanioka, Takeshi Ito. Matrix metalloproteinase-9 in macrophages induces thymic neovascularization following thymocyte apoptosis. Journal of immunology (Baltimore, Md. : 1950). vol 174. issue 2. 2005-03-03. PMID:15634906. |
these studies demonstrate a potential role of macrophage mmp-9 in the remodeling of thymic extracellular matrix following thymocyte apoptosis. |
2005-03-03 |
2023-08-12 |
mouse |
| Rujun Gong, Abdalla Rifai, Evelyn M Tolbert, Purba Biswas, Jason N Centracchio, Lance D Dworki. Hepatocyte growth factor ameliorates renal interstitial inflammation in rat remnant kidney by modulating tubular expression of macrophage chemoattractant protein-1 and RANTES. Journal of the American Society of Nephrology : JASN. vol 15. issue 11. 2005-03-02. PMID:15504940. |
suggested mechanisms to explain this action include prevention of tubular cell apoptosis, blocking epithelial-to-mesenchymal transition, and promotion of extracellular matrix degradation. |
2005-03-02 |
2023-08-12 |
rat |
| Pauli A Puolakkainen, Rolf A Brekken, Sabeeha Muneer, E Helene Sag. Enhanced growth of pancreatic tumors in SPARC-null mice is associated with decreased deposition of extracellular matrix and reduced tumor cell apoptosis. Molecular cancer research : MCR. vol 2. issue 4. 2005-02-18. PMID:15140943. |
enhanced growth of pancreatic tumors in sparc-null mice is associated with decreased deposition of extracellular matrix and reduced tumor cell apoptosis. |
2005-02-18 |
2023-08-12 |
mouse |
| Harald Bradl, Wolfgang Schuh, Hans-Martin Jäc. CD44 is dispensable for B lymphopoiesis. Immunology letters. vol 95. issue 1. 2005-02-11. PMID:15325800. |
several studies have implicated a role for the cell surface glycoprotein cd44 in lymphocyte differentiation, adhesion to the matrix, homing, activation and apoptosis. |
2005-02-11 |
2023-08-12 |
mouse |
| Li Guo, Stephen E Moss, Robert A Alexander, Robin R Ali, Frederick W Fitzke, M Francesca Cordeir. Retinal ganglion cell apoptosis in glaucoma is related to intraocular pressure and IOP-induced effects on extracellular matrix. Investigative ophthalmology & visual science. vol 46. issue 1. 2005-02-10. PMID:15623771. |
retinal ganglion cell apoptosis in glaucoma is related to intraocular pressure and iop-induced effects on extracellular matrix. |
2005-02-10 |
2023-08-12 |
rat |
| Li Guo, Stephen E Moss, Robert A Alexander, Robin R Ali, Frederick W Fitzke, M Francesca Cordeir. Retinal ganglion cell apoptosis in glaucoma is related to intraocular pressure and IOP-induced effects on extracellular matrix. Investigative ophthalmology & visual science. vol 46. issue 1. 2005-02-10. PMID:15623771. |
to investigate the effect of iop on retinal ganglion cell (rgc) apoptosis and correlate the effects with iop-induced changes in extracellular matrix (ecm) in the retina and optic nerve head (onh) in glaucomatous rat eyes. |
2005-02-10 |
2023-08-12 |
rat |
| Moisés Selman, Annie Pard. Idiopathic pulmonary fibrosis: misunderstandings between epithelial cells and fibroblasts? Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG. vol 21. issue 3. 2005-02-07. PMID:15554072. |
active fibroblasts/myofibroblasts from these foci may in turn disturb alveolar re-epithelialization, by provoking basement membrane disruption and epithelial cell apoptosis finally resulting in exaggerated extracellular matrix accumulation. |
2005-02-07 |
2023-08-12 |
Not clear |