| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Se-Jin Chung, Se-Hee Lee, Yong-Jin Lee, Hyoung-Sook Park, Rolf Bünger, Young-Hee Kan. Pyruvate protection against endothelial cytotoxicity induced by blockade of glucose uptake. Journal of biochemistry and molecular biology. vol 37. issue 2. 2004-10-28. PMID:15469702. |
we have previously demonstrated that the redox reactant pyruvate prevents apoptosis in the oxidant model of bovine pulmonary artery endothelial cells (bpaec), and that the anti-apoptotic mechanism of pyruvate is mediated in part via the mitochondrial matrix compartment. |
2004-10-28 |
2023-08-12 |
cattle |
| E Sivridis, A Giatromanolak. New insights into the normal menstrual cycle-regulatory molecules. Histology and histopathology. vol 19. issue 2. 2004-10-25. PMID:15024712. |
at the same time, other proteins promote endometrial cell survival by preventing extracellular matrix degradation and apoptosis. |
2004-10-25 |
2023-08-12 |
Not clear |
| Natsuko Horiguchi, Kei-ichiro Arimoto, Atsushi Mizutani, Yoko Endo-Ichikawa, Hiroshi Nakada, Shigeru Taketan. Galectin-1 induces cell adhesion to the extracellular matrix and apoptosis of non-adherent human colon cancer Colo201 cells. Journal of biochemistry. vol 134. issue 6. 2004-10-21. PMID:14769876. |
galectin-1 induces cell adhesion to the extracellular matrix and apoptosis of non-adherent human colon cancer colo201 cells. |
2004-10-21 |
2023-08-12 |
human |
| Anastasios Tahmatzopoulos, Randall G Rowland, Natasha Kypriano. The role of alpha-blockers in the management of prostate cancer. Expert opinion on pharmacotherapy. vol 5. issue 6. 2004-10-21. PMID:15163273. |
specifically, doxazosin and terazosin can induce apoptosis, inhibit invasion and migration of prostate cancer and endothelial cells, and reduce their adhesion potential to extracellular matrix components, thus enhancing their susceptibility to anoikis. |
2004-10-21 |
2023-08-12 |
Not clear |
| Thomas Pietri, Olivier Eder, Marie Anne Breau, Piotr Topilko, Martine Blanche, Cord Brakebusch, Reinhard Fässler, Jean-Paul Thiery, Sylvie Dufou. Conditional beta1-integrin gene deletion in neural crest cells causes severe developmental alterations of the peripheral nervous system. Development (Cambridge, England). vol 131. issue 16. 2004-10-21. PMID:15253938. |
integrins are transmembrane receptors that are known to interact with the extracellular matrix and to be required for migration, proliferation, differentiation and apoptosis. |
2004-10-21 |
2023-08-12 |
mouse |
| N Philips, D Burchill, D O'Donoghue, T Keller, S Gonzale. Identification of benzene metabolites in dermal fibroblasts as nonphenolic: regulation of cell viability, apoptosis, lipid peroxidation and expression of matrix metalloproteinase 1 and elastin by benzene metabolites. Skin pharmacology and physiology. vol 17. issue 3. 2004-10-19. PMID:15087594. |
identification of benzene metabolites in dermal fibroblasts as nonphenolic: regulation of cell viability, apoptosis, lipid peroxidation and expression of matrix metalloproteinase 1 and elastin by benzene metabolites. |
2004-10-19 |
2023-08-12 |
Not clear |
| Pekka Koistinen, Matti Ahonen, Veli-Matti Kähäri, Jyrki Hein. alphaV integrin promotes in vitro and in vivo survival of cells in metastatic melanoma. International journal of cancer. vol 112. issue 1. 2004-10-19. PMID:15305376. |
in cell culture experiments, the depletion of alphav integrins detached cells from extracellular matrix and induced apoptosis. |
2004-10-19 |
2023-08-12 |
mouse |
| A Mirshafiey, D T Ngoc Dzung, J W Murphy, M R Khorramizadeh, F Saadat, F Mehrabian, P Larsso. Tolerability and anti-inflammatory effects of glucuronoxylomannan in collagen-induced arthritis. Scandinavian journal of immunology. vol 60. issue 3. 2004-10-14. PMID:15320878. |
the wehi-164 cell line was used for assaying tolerability, matrix metalloproteinase type 2 (mmp-2) activity and apoptosis. |
2004-10-14 |
2023-08-12 |
rat |
| Jun Luo, Shang-Tian Yan. Effects of three-dimensional culturing in a fibrous matrix on cell cycle, apoptosis, and MAb production by hybridoma cells. Biotechnology progress. vol 20. issue 1. 2004-10-08. PMID:14763857. |
effects of three-dimensional culturing in a fibrous matrix on cell cycle, apoptosis, and mab production by hybridoma cells. |
2004-10-08 |
2023-08-12 |
Not clear |
| Jun Luo, Shang-Tian Yan. Effects of three-dimensional culturing in a fibrous matrix on cell cycle, apoptosis, and MAb production by hybridoma cells. Biotechnology progress. vol 20. issue 1. 2004-10-08. PMID:14763857. |
the effects of culturing hybridoma cells in a three-dimensional (3-d) poly(ethylene terephthalate) (pet) fibrous matrix on cell cycle, apoptosis, metabolism, and monoclonal antibody (mab) production were evaluated by comparing with two-dimensional (2-d) culturing on microcarrier and multiwell plate surfaces. |
2004-10-08 |
2023-08-12 |
Not clear |
| Jun Luo, Shang-Tian Yan. Effects of three-dimensional culturing in a fibrous matrix on cell cycle, apoptosis, and MAb production by hybridoma cells. Biotechnology progress. vol 20. issue 1. 2004-10-08. PMID:14763857. |
these results suggested that the 3-d fibrous matrix contributed to growth arrest, protected cells to better resist low-serum environments, and reduced apoptosis, all of which contributed to the high viable cell density and volumetric mab productivity in the long-term 3-d culture. |
2004-10-08 |
2023-08-12 |
Not clear |
| Dian J Cao, Yan-Lin Guo, Robert W Colma. Urokinase-type plasminogen activator receptor is involved in mediating the apoptotic effect of cleaved high molecular weight kininogen in human endothelial cells. Circulation research. vol 94. issue 9. 2004-10-07. PMID:15044324. |
we have shown that hka-induced apoptosis correlated with its antiadhesive effect and was regulated by extracellular matrix (ecm) proteins. |
2004-10-07 |
2023-08-12 |
human |
| Tongalp H Tezel, Lucian V Del Priore, Henry J Kapla. Reengineering of aged Bruch's membrane to enhance retinal pigment epithelium repopulation. Investigative ophthalmology & visual science. vol 45. issue 9. 2004-10-07. PMID:15326159. |
the present study was undertaken to determine the effect of cleaning and/or an extracellular matrix (ecm) protein coating on the reattachment, apoptosis, proliferation, and final surface coverage of the transplanted rpe cells. |
2004-10-07 |
2023-08-12 |
human |
| Christina K Yung, Victoria L Halperin, Gordon F Tomaselli, Raimond L Winslo. Gene expression profiles in end-stage human idiopathic dilated cardiomyopathy: altered expression of apoptotic and cytoskeletal genes. Genomics. vol 83. issue 2. 2004-10-06. PMID:14706457. |
these regulated genes take part in diverse cellular processes, including transcription, apoptosis, sarcomeric and cytoskeletal function, remodeling of the extracellular matrix, membrane transport, and metabolism. |
2004-10-06 |
2023-08-12 |
human |
| M Kasper, D Seidel, L Knels, N Morishima, A Neisser, S Bramke, R Koslowsk. Early signs of lung fibrosis after in vitro treatment of rat lung slices with CdCl2 and TGF-beta1. Histochemistry and cell biology. vol 121. issue 2. 2004-10-05. PMID:14752665. |
three days of cdcl(2) exposure in combination with tgf-beta(1) seem to be sufficient to induce lung injury with alterations similar to changes observed in early lung fibrogenesis: (1) extracellular matrix accumulation and myofibroblast transdifferentiation (sirius red staining, collagen type iv, alpha-smooth muscle actin), (2) type i cell injury with loss of type i cell antigens (t1alpha antigen, aquaporin-5, rage), (3) increased apoptosis of pulmonary cells (active caspase-3, vimentin cleavage product v1 of caspase-9), and (4) activation of microvascular endothelial cells (podocalyxin, caveolin-1). |
2004-10-05 |
2023-08-12 |
rat |
| Masaharu Yamazaki, Takemi Akahane, Todd Buck, Hitoshi Yoshiji, Daniel E Gomez, Daniel J Schoeffner, Eijiro Okajima, Steven R Harris, Opal R Bunce, Snorri S Thorgeirsson, Unnur P Thorgeirsso. Long-term exposure to elevated levels of circulating TIMP-1 but not mammary TIMP-1 suppresses growth of mammary carcinomas in transgenic mice. Carcinogenesis. vol 25. issue 9. 2004-10-05. PMID:15166086. |
tissue inhibitor of metalloproteinases-1 (timp-1) regulates matrix metalloproteinase activity, acts as a growth stimulator and inhibits apoptosis. |
2004-10-05 |
2023-08-12 |
mouse |
| Laura de la Cruz, Kristin Steffgen, Andrea Martin, Carli McGee, Helen Hathawa. Apoptosis and involution in the mammary gland are altered in mice lacking a novel receptor, beta1,4-Galactosyltransferase I. Developmental biology. vol 272. issue 2. 2004-10-04. PMID:15282149. |
apoptosis and involution in the mammary gland are altered in mice lacking a novel receptor, beta1,4-galactosyltransferase i. receptor-mediated cell-extracellular matrix (ecm) interactions are critical regulators of cell survival, and perturbing these signaling pathways can disrupt cellular differentiation and function in a variety of tissues, including the mammary gland. |
2004-10-04 |
2023-08-12 |
mouse |
| Sarah Kraus, Gal Levy, Tamar Hanoch, Zvi Naor, Rony Sege. Gonadotropin-releasing hormone induces apoptosis of prostate cancer cells: role of c-Jun NH2-terminal kinase, protein kinase B, and extracellular signal-regulated kinase pathways. Cancer research. vol 64. issue 16. 2004-09-30. PMID:15313914. |
interestingly, extracellular signal-regulated kinase is also activated by gnrh-a, and this occurs via a pathway that involves matrix metalloproteinases and epidermal growth factor receptor, but its activation does not affect jnk activation and the gnrh-a-induced apoptosis. |
2004-09-30 |
2023-08-12 |
Not clear |
| X H Luo, E Y Liao, H J Liao, Y Jin, H D Zhou, G Huan. Recombinant matrix metalloproteinase-14 catalytic domain induces apoptosis in human osteoblastic SaOS-2 cells. Journal of endocrinological investigation. vol 26. issue 11. 2004-09-28. PMID:15008250. |
recombinant matrix metalloproteinase-14 catalytic domain induces apoptosis in human osteoblastic saos-2 cells. |
2004-09-28 |
2023-08-12 |
human |
| Allan Lipto. Pathophysiology of bone metastases: how this knowledge may lead to therapeutic intervention. The journal of supportive oncology. vol 2. issue 3. 2004-09-28. PMID:15328823. |
bisphosphonates bind avidly to the bone matrix, are released during bone resorption, and are subsequently internalized by osteoclasts, where they interfere with biochemical pathways and induce osteoclast apoptosis. |
2004-09-28 |
2023-08-12 |
Not clear |