Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
J Barry Wright, Kan Lam, Andre G Buret, Merle E Olson, Robert E Burrel. Early healing events in a porcine model of contaminated wounds: effects of nanocrystalline silver on matrix metalloproteinases, cell apoptosis, and healing. Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society. vol 10. issue 3. 2002-09-27. PMID:12100375. |
these benefits are associated with reduced local matrix metalloproteinase levels and enhanced cellular apoptosis. |
2002-09-27 |
2023-08-12 |
Not clear |
Anne-Marie Preaux, Marie-Pia D'ortho, Marie-Pierre Bralet, Yannick Laperche, Philippe Mavie. Apoptosis of human hepatic myofibroblasts promotes activation of matrix metalloproteinase-2. Hepatology (Baltimore, Md.). vol 36. issue 3. 2002-09-27. PMID:12198653. |
apoptosis of human hepatic myofibroblasts promotes activation of matrix metalloproteinase-2. |
2002-09-27 |
2023-08-12 |
human |
Anne-Marie Preaux, Marie-Pia D'ortho, Marie-Pierre Bralet, Yannick Laperche, Philippe Mavie. Apoptosis of human hepatic myofibroblasts promotes activation of matrix metalloproteinase-2. Hepatology (Baltimore, Md.). vol 36. issue 3. 2002-09-27. PMID:12198653. |
fibrosis resolution is characterized by apoptosis of hepatic myofibroblasts and degradation of extracellular matrix components. |
2002-09-27 |
2023-08-12 |
human |
Justus Gille, Eva-M Ehlers, Mathias Okroi, Martin Russlies, Peter Behren. Apoptotic chondrocyte death in cell-matrix biocomposites used in autologous chondrocyte transplantation. Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft. vol 184. issue 4. 2002-09-24. PMID:12201041. |
it is known that matrix provides a trophic signal for the cells and an altered matrix may influence the availability of factors that regulate apoptosis. |
2002-09-24 |
2023-08-12 |
Not clear |
Johanna Laukkanen, Seppo Ylä-Herttual. Genes involved in atherosclerosis. Experimental nephrology. vol 10. issue 2. 2002-09-17. PMID:11937762. |
the purpose of this article is to focus on the arterial wall and to review lipoprotein receptors, growth factors, cytokines, chemokines, matrix metalloproteinases, adhesion molecules, and apoptosis genes and their involvement in atherogenesis. |
2002-09-17 |
2023-08-12 |
Not clear |
X Luan, T G H Diekwisc. CP27 affects viability, proliferation, attachment and gene expression in embryonic fibroblasts. Cell proliferation. vol 35. issue 4. 2002-09-13. PMID:12153613. |
following cell culture, cell viability, apoptosis, cell proliferation, cell shape, cellular attachment and fibronectin matrix production were assayed using mtt colourimetric assay, brdu staining, morphometry, immunostaining and western blot analysis. |
2002-09-13 |
2023-08-12 |
rabbit |
Maria P Morgan, Geraldine M McCarth. Signaling mechanisms involved in crystal-induced tissue damage. Current opinion in rheumatology. vol 14. issue 3. 2002-09-12. PMID:11981329. |
some of the downstream effects known to date include increased mitogenesis, up-regulation of members of the matrix metalloproteinase family, down-regulation of tissue inhibitor of metalloproteinase-1 and -2 in fibroblasts, induction of neutrophil chemotactic chemokines such as interleukin-8, activation and degranulation of neutrophils, and inhibition of neutrophil apoptosis. |
2002-09-12 |
2023-08-12 |
Not clear |
S Yamasaki, T Nakashima, A Kawakami, T Miyashita, H Ida, K Migita, K Nakata, K Eguch. Functional changes in rheumatoid fibroblast-like synovial cells through activation of peroxisome proliferator-activated receptor gamma-mediated signalling pathway. Clinical and experimental immunology. vol 129. issue 2. 2002-09-11. PMID:12165097. |
incubation of fls with a synthetic ppargamma ligand, troglitazone, inhibited endogenous production of tnf-alpha, il-6 and il-8, as well as matrix metalloprotease-3 (mmp-3), without inducing apoptosis of the cells. |
2002-09-11 |
2023-08-12 |
Not clear |
William A Ricke, George W Smith, Eric W McIntush, Michael F Smit. Analysis of luteal tissue inhibitor of metalloproteinase-1, -2, and -3 during prostaglandin F(2alpha)-induced luteolysis. Biology of reproduction. vol 66. issue 5. 2002-09-10. PMID:11967202. |
increased matrix metalloproteinase (mmp) expression and activities help to mediate tissue involution through increasing extracellular matrix remodeling and promoting dedifferentiation and, ultimately, apoptosis. |
2002-09-10 |
2023-08-12 |
Not clear |
F Luchetti, S Burattini, P Ferri, S Papa, E Falcier. Actin involvement in apoptotic chromatin changes of hemopoietic cells undergoing hyperthermia. Apoptosis : an international journal on programmed cell death. vol 7. issue 2. 2002-08-30. PMID:11865198. |
we suggest that, similarly to the role played by nuclear matrix in interphase and mitotic nucleus, actin could be directly involved in chromatin rearrangement occurring in apoptosis. |
2002-08-30 |
2023-08-12 |
Not clear |
Marc J Curtis, Thomas J Wolper. The oat mitochondrial permeability transition and its implication in victorin binding and induced cell death. The Plant journal : for cell and molecular biology. vol 29. issue 3. 2002-08-16. PMID:11844107. |
previous results suggest that a mpt may facilitate victorin's access to the mitochondrial matrix and binding to the p-protein: (i) victorin-induced cell death displays features similar to apoptosis; (ii) in vivo, victorin binds to the mitochondrial p-protein only in toxin-sensitive genotypes whereas victorin binds equally well to p-protein isolated from toxin-sensitive and insensitive oats; (iii) isolated, untreated mitochondria are impermeable to victorin. |
2002-08-16 |
2023-08-12 |
rat |
Wenbiao Liu, Niels Reinmuth, Oliver Stoeltzing, Alexander A Parikh, Fan Fan, Syed A Ahmad, Young D Jung, Lee M Elli. Antiangiogenic therapy targeting factors that enhance endothelial cell survival. Seminars in oncology. vol 29. issue 3 Suppl 11. 2002-08-14. PMID:12138403. |
integrins may function as ec survival factors by preventing apoptosis by numerous mechanisms mediated by binding to the extracellular matrix. |
2002-08-14 |
2023-08-12 |
Not clear |
Matthew J Hunt, Giorgio M Aru, Melvin R Hayden, Charles K Moore, Brian D Hoit, Suresh C Tyag. Induction of oxidative stress and disintegrin metalloproteinase in human heart end-stage failure. American journal of physiology. Lung cellular and molecular physiology. vol 283. issue 2. 2002-08-12. PMID:12114184. |
however, a complete separation between the matrix and the cell leads to apoptosis, dilatation, and failure. |
2002-08-12 |
2023-08-12 |
human |
Magdalena M Serewko, Claudia Popa, Alison L Dahler, Louise Smith, Geoff M Strutton, William Coman, Anthony J Dicker, Nicholas A Saunder. Alterations in gene expression and activity during squamous cell carcinoma development. Cancer research. vol 62. issue 13. 2002-08-08. PMID:12097286. |
our analysis indicated that alterations in genes associated with extracellular matrix production and apoptosis are disrupted in preneoplastic cells, whereas later stages of neoplasia are associated with alterations in gene expression for genes involved in dna repair or epidermal growth factor (egf) receptor/mitogen-activated protein kinase kinase (mapkk)/mapk/activator protein-1 (ap-1) signaling. |
2002-08-08 |
2023-08-12 |
human |
K Takamura, N Oka, A Akagi, K Okamoto, T Okada, T Fukuoka, A Hogaki, D Naito, Y Oobayashi, N Sato. EST analysis of genes that are expressed in the neural complex of Ciona intestinalis adults. Zoological science. vol 18. issue 9. 2002-08-06. PMID:11911079. |
among the clones matching previously identified proteins, about 80 clones represented proteins that are involved in the formation, maintenance of the structure, and function of the nervous system: 22 proteins are associated with signal transduction, five proteins are related to the synapse, 11 to transcription factors, nine to transporters, five to enzymes, and 13 to extracellular matrix and cytoskeletal components, and six to apoptosis. |
2002-08-06 |
2023-08-12 |
Not clear |
Janine M Prince, Teresa C M Klinowska, Emma Marshman, Emma T Lowe, Ulrike Mayer, Jeff Miner, Daniel Aberdam, Dietmar Vestweber, Barry Gusterson, Charles H Streul. Cell-matrix interactions during development and apoptosis of the mouse mammary gland in vivo. Developmental dynamics : an official publication of the American Association of Anatomists. vol 223. issue 4. 2002-08-06. PMID:11921338. |
to explore the possibility that dynamic changes in cell-matrix interactions contribute to the onset of apoptosis during mammary involution in vivo, a detailed immunohistochemical analysis of the expression of integrin subunits and their extracellular matrix ligands during mouse mammary gland development has been performed. |
2002-08-06 |
2023-08-12 |
mouse |
Janine M Prince, Teresa C M Klinowska, Emma Marshman, Emma T Lowe, Ulrike Mayer, Jeff Miner, Daniel Aberdam, Dietmar Vestweber, Barry Gusterson, Charles H Streul. Cell-matrix interactions during development and apoptosis of the mouse mammary gland in vivo. Developmental dynamics : an official publication of the American Association of Anatomists. vol 223. issue 4. 2002-08-06. PMID:11921338. |
this finding may provide a novel dynamic mechanism for inhibiting the transduction of extracellular matrix survival signals, thereby contributing to the onset of apoptosis in a developmental context in vivo. |
2002-08-06 |
2023-08-12 |
mouse |
Suyun Huang, Lisa Mills, Badar Mian, Carmen Tellez, Marya McCarty, X-D Yang, Jean M Gudas, Menashe Bar-El. Fully humanized neutralizing antibodies to interleukin-8 (ABX-IL8) inhibit angiogenesis, tumor growth, and metastasis of human melanoma. The American journal of pathology. vol 161. issue 1. 2002-08-06. PMID:12107097. |
in vivo, abx-il8 treatment resulted in decreased expression of matrix metalloproteinase-2, and decreased vascularization (angiogenesis) of tumors concomitant with increased apoptosis of tumor cells. |
2002-08-06 |
2023-08-12 |
mouse |
L A Hazlehurst, W S Dalto. Mechanisms associated with cell adhesion mediated drug resistance (CAM-DR) in hematopoietic malignancies. Cancer metastasis reviews. vol 20. issue 1-2. 2002-07-30. PMID:11831646. |
for hematopoietic tumors, cell adhesion to a single matrix, fibronectin is sufficient to inhibit apoptosis induced by mechanistically distinct cyctotoxics. |
2002-07-30 |
2023-08-12 |
human |
Ursula Mirastschijski, Ulla Impola, Morten A Karsdal, Ulpu Saarialho-Kere, Magnus S Agre. Matrix metalloproteinase inhibitor BB-3103 unlike the serine proteinase inhibitor aprotinin abrogates epidermal healing of human skin wounds ex vivo. The Journal of investigative dermatology. vol 118. issue 1. 2002-07-25. PMID:11851876. |
lack of epithelialization was unlikely due to cytotoxicity because the matrix metalloproteinase inhibitor did neither influence viability of cultured epidermal keratinocytes nor apoptosis in wounds. |
2002-07-25 |
2023-08-12 |
human |