| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mari T Kaartinen, Sherif El-Maadawy, Niina H Räsänen, Marc D McKe. Tissue transglutaminase and its substrates in bone. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. vol 17. issue 12. 2003-05-16. PMID:12469910. |
tissue transglutaminase (ttg) is an intra- and extracellular, protein-cross-linking enzyme that has been implicated in apoptosis, matrix stabilization, and cell attachment in a variety of tissues. |
2003-05-16 |
2023-08-12 |
rat |
| Sung-Yu Hong, Hyeryung Lee, Weon-Kyoo You, Kwang-Hoe Chung, Doo-Sik Kim, Kiwon Son. The snake venom disintegrin salmosin induces apoptosis by disassembly of focal adhesions in bovine capillary endothelial cells. Biochemical and biophysical research communications. vol 302. issue 3. 2003-05-13. PMID:12615062. |
these observations strongly suggest that salmosin disorganizes focal contacts to detach cells by competing with the extracellular matrix (ecm) for direct binding to integrin alpha(v)beta(3) on the cell surface, eventually leading to apoptosis. |
2003-05-13 |
2023-08-12 |
cattle |
| L V Kremneva, O V Abaturov. [Molecular and cellular mechanisms of myocardial remodeling in heart failure]. Klinicheskaia meditsina. vol 81. issue 2. 2003-05-07. PMID:12685226. |
the apoptosis of smooth muscle cells, the translocation, structural and functional impairments of remaining cardiomyocytes, ventricular dilatation, and the altered extracellular matrix underlie myocardial remodeling in chronic heart failure (chf). |
2003-05-07 |
2023-08-12 |
Not clear |
| Sarah A Kopecky, Douglas S Lyle. Contrasting effects of matrix protein on apoptosis in HeLa and BHK cells infected with vesicular stomatitis virus are due to inhibition of host gene expression. Journal of virology. vol 77. issue 8. 2003-05-05. PMID:12663772. |
contrasting effects of matrix protein on apoptosis in hela and bhk cells infected with vesicular stomatitis virus are due to inhibition of host gene expression. |
2003-05-05 |
2023-08-12 |
Not clear |
| Sarah A Kopecky, Douglas S Lyle. Contrasting effects of matrix protein on apoptosis in HeLa and BHK cells infected with vesicular stomatitis virus are due to inhibition of host gene expression. Journal of virology. vol 77. issue 8. 2003-05-05. PMID:12663772. |
recently, it has been shown that two vsv products are involved in the induction of apoptosis, the matrix (m) protein, and another viral product that has yet to be identified (s. a. kopecky et. |
2003-05-05 |
2023-08-12 |
Not clear |
| b' Z Humlov\\xc3\\xa. Protooncogene bcl-2 in process of apoptosis. Review article. Sbornik lekarsky. vol 103. issue 4. 2003-04-29. PMID:12688154.' |
changes in the flux of ions and water across the inner mitochondrial membrane characterize the early phase of apoptosis, during which an increase in matrix volume may precede a collapse of mitochondrial membrane potential (delta psi m). |
2003-04-29 |
2023-08-12 |
Not clear |
| Victoria M L Herrera, Tamara Didishvili, Lyle V Lopez, Nelson Ruiz-Opaz. Differential regulation of functional gene clusters in overt coronary artery disease in a transgenic atherosclerosis-hypertensive rat model. Molecular medicine (Cambridge, Mass.). vol 8. issue 7. 2003-04-16. PMID:12393934. |
typically studied as distinct pathologies, emerging pathogenic paradigms implicate multiple processes beyond thrombosis and ischemic cell injury respectively, with significant pathway overlap involving inflammation, apoptosis, matrix degradation, and oxidative stress. |
2003-04-16 |
2023-08-12 |
human |
| Ding Yu, Zihui Wang, Liyuan Zhu, E C Che. Nuclear matrix associated protein PML: an arsenic trioxide apoptosis therapeutic target protein in HepG2 cells. Chinese medical journal. vol 116. issue 1. 2003-04-15. PMID:12667397. |
nuclear matrix associated protein pml: an arsenic trioxide apoptosis therapeutic target protein in hepg2 cells. |
2003-04-15 |
2023-08-12 |
Not clear |
| Ding Yu, Zihui Wang, Liyuan Zhu, E C Che. Nuclear matrix associated protein PML: an arsenic trioxide apoptosis therapeutic target protein in HepG2 cells. Chinese medical journal. vol 116. issue 1. 2003-04-15. PMID:12667397. |
to investigate arsenic trioxide (as(2)o(3))-induced apoptosis and the effects on cell nuclear matrix related protein promyelocytic leukaemia (pml). |
2003-04-15 |
2023-08-12 |
Not clear |
| Feng Jiang, Zhou Wan. Identification of androgen-responsive genes in the rat ventral prostate by complementary deoxyribonucleic acid subtraction and microarray. Endocrinology. vol 144. issue 4. 2003-04-10. PMID:12639908. |
the identified genes can be classified into several functional groups, including metabolism, protein chaperoning and trafficking, protein synthesis, secretions, cell cycle and apoptosis, structural and extracellular matrix proteins, and novel proteins. |
2003-04-10 |
2023-08-12 |
rat |
| Inder S Anan. Ventricular remodeling without cellular contractile dysfunction. Journal of cardiac failure. vol 8. issue 6 Suppl. 2003-04-08. PMID:12555152. |
important among these are loss of myocytes from necrosis or apoptosis, changes in the extracellular matrix (ecm), myocyte contractile dysfunction, and the purely geometric or mechanical effects of structural alterations in the lv. |
2003-04-08 |
2023-08-12 |
Not clear |
| Juan Arredondo, Vu Thuong Nguyen, Alexander I Chernyavsky, Dani Bercovich, Avi Orr-Urtreger, Douglas E Vetter, Sergei A Grand. Functional role of alpha7 nicotinic receptor in physiological control of cutaneous homeostasis. Life sciences. vol 72. issue 18-19. 2003-04-04. PMID:12628457. |
we studied in vitro effects of functional inactivation of alpha7 receptor on the expression of apoptosis regulators in keratinocytes (kc) lacking alpha7 nachr, and extracellular matrix regulators in the skin of alpha7 knockout (ko) mice. |
2003-04-04 |
2023-08-12 |
mouse |
| Christopher S Adams, Irving M Shapir. The fate of the terminally differentiated chondrocyte: evidence for microenvironmental regulation of chondrocyte apoptosis. Critical reviews in oral biology and medicine : an official publication of the American Association of Oral Biologists. vol 13. issue 6. 2003-03-28. PMID:12499240. |
since the induction of apoptosis is spatially and temporally linked to the removal of the cartilage matrix, current studies have examined the apoptogenic activity of ca(2+)-, pi-, and rgd-containing peptides of extracellular matrix proteins. |
2003-03-28 |
2023-08-12 |
Not clear |
| G R Nigri, C Brini, G M LaMuraglia, F Vietr. [Photodynamic therapy in cardiac and vascular surgery]. Il Giornale di chirurgia. vol 23. issue 8-9. 2003-03-26. PMID:12564301. |
these free radicals are able to induce apoptosis of the smooth muscle cells that had absorbed the photosensitizer; they also induce changes in the extracellular matrix, reducing cell migration. |
2003-03-26 |
2023-08-12 |
Not clear |
| Emilia Maneiro, Miguel A Martín, María C de Andres, Maria J López-Armada, José L Fernández-Sueiro, Pilar del Hoyo, Fausto Galdo, Joaquin Arenas, Francisco J Blanc. Mitochondrial respiratory activity is altered in osteoarthritic human articular chondrocytes. Arthritis and rheumatism. vol 48. issue 3. 2003-03-25. PMID:12632423. |
osteoarthritis (oa) is a degenerative rheumatic disease that is associated with extracellular matrix degradation and chondrocyte apoptosis in the articular cartilage. |
2003-03-25 |
2023-08-12 |
human |
| Hafiz Ahmed, Mario A Bianchet, L Mario Amzel, Jun Hirabayashi, Ken-Ichi Kasai, Yuko Giga-Hama, Hideki Tohda, Gerardo R Vast. Novel carbohydrate specificity of the 16-kDa galectin from Caenorhabditis elegans: binding to blood group precursor oligosaccharides (type 1, type 2, Talpha, and Tbeta) and gangliosides. Glycobiology. vol 12. issue 8. 2003-03-20. PMID:12145186. |
galectins, a family of soluble beta-galactosyl-binding lectins, are believed to mediate cell-cell and cell-extracellular matrix interactions during development, inflammation, apoptosis, and tumor metastasis. |
2003-03-20 |
2023-08-12 |
caenorhabditis_elegans |
| V A Tronov, E M Konstantinov, I I Kramarenk. [Hyperthermia induced signal for apoptosis and pathways of its transduction in the cell]. Tsitologiia. vol 44. issue 11. 2003-03-19. PMID:12561728. |
in this regard we analyse the membrane effect of ht, ht-induced chromatin and nuclear matrix structure changes, dna damage, effect of ht on dna-repair mechanism, and the role of heat shock proteins in apoptosis and cancerogenesis. |
2003-03-19 |
2023-08-12 |
Not clear |
| Philippe Clézardi. The antitumor potential of bisphosphonates. Seminars in oncology. vol 29. issue 6 Suppl 21. 2003-03-18. PMID:12584693. |
bisphosphonates reduce proliferation and induce apoptosis of tumor cell lines, and they inhibit tumor cell adhesion and invasion of the extracellular matrix in vitro. |
2003-03-18 |
2023-08-12 |
Not clear |
| Ze'ev Hochber. Mechanisms of steroid impairment of growth. Hormone research. vol 58 Suppl 1. 2003-03-17. PMID:12373012. |
direct effects at the growth plate include the suppression of multiple gene expression, chondrocyte proliferation and matrix proteoglycan synthesis, sulfation, release and mineralization as well as the augmentation of hypertrophic cell apoptosis. |
2003-03-17 |
2023-08-12 |
Not clear |
| Vincent H Gattone, Justin L Ricker, Chad M Trambaugh, Robert M Klei. Multiorgan mRNA misexpression in murine autosomal recessive polycystic kidney disease. Kidney international. vol 62. issue 5. 2003-03-12. PMID:12371956. |
in cystic kidneys, misexpressed mrnas were found in one of four general groups: proliferation/cell growth, apoptosis, differentiation or extracellular matrix. |
2003-03-12 |
2023-08-12 |
mouse |