| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Galina T Shishkina, Tatyana S Kalinina, Nikolay N Dygal. Serotonergic changes produced by repeated exposure to forced swimming: correlation with behavior. Annals of the New York Academy of Sciences. vol 1148. 2009-01-23. PMID:19120103. |
this stressor also increased the mrna levels for tryptophan hydroxylase-2, the rate-limiting enzyme in neuronal 5-ht synthesis, and 5-ht transporter in the midbrain as well as 5-ht1a receptor in the frontal cortex. |
2009-01-23 |
2023-08-12 |
Not clear |
| Jon R Nash, Peter A Sargent, Eugenii A Rabiner, Sean D Hood, Spilios V Argyropoulos, John P Potokar, Paul M Grasby, David J Nut. Serotonin 5-HT1A receptor binding in people with panic disorder: positron emission tomography study. The British journal of psychiatry : the journal of mental science. vol 193. issue 3. 2009-01-22. PMID:18757983. |
serotonin 5-ht1a receptor binding in people with panic disorder: positron emission tomography study. |
2009-01-22 |
2023-08-12 |
mouse |
| Sanjay J Mathew, Amir Garakani, John F Reinhard, Scott Oshana, Stephen Donahu. Short-term tolerability of a nonazapirone selective serotonin 1A agonist in adults with generalized anxiety disorder: a 28-day, open-label study. Clinical therapeutics. vol 30. issue 9. 2009-01-06. PMID:18840371. |
the serotonin 1a (5-hydroxytryptamine 1a [5-ht1a]) receptor likely plays a critical role in anxiety pathophysiology. |
2009-01-06 |
2023-08-12 |
Not clear |
| Benicio N Frey, Pedro Rosa-Neto, Stuart Lubarsky, Mirko Diksi. Correlation between serotonin synthesis and 5-HT1A receptor binding in the living human brain: a combined alpha-[11C]MT and [18F]MPPF positron emission tomography study. NeuroImage. vol 42. issue 2. 2008-12-08. PMID:18583156. |
correlation between serotonin synthesis and 5-ht1a receptor binding in the living human brain: a combined alpha-[11c]mt and [18f]mppf positron emission tomography study. |
2008-12-08 |
2023-08-12 |
human |
| Nicole T Hatzenbuhler, Reinhardt Baudy, Deborah A Evrard, Amedeo Failli, Boyd L Harrison, Steven Lenicek, Richard E Mewshaw, Annmarie Saab, Uresh Shah, Jean Sze, Minsheng Zhang, Dahui Zhou, Michael Chlenov, Michael Kagan, Jeannette Golembieski, Geoffrey Hornby, Margaret Lai, Deborah L Smith, Kelly M Sullivan, Lee E Schechter, Terrance H Andre. Advances toward new antidepressants with dual serotonin transporter and 5-HT1A receptor affinity within a class of 3-aminochroman derivatives. Part 2. Journal of medicinal chemistry. vol 51. issue 21. 2008-11-28. PMID:18834188. |
advances toward new antidepressants with dual serotonin transporter and 5-ht1a receptor affinity within a class of 3-aminochroman derivatives. |
2008-11-28 |
2023-08-12 |
rat |
| K Wedzony, A Chocyk, M Maćkowia. A search for colocalization of serotonin 5-HT2A and 5-HT1A receptors in the rat medial prefrontal and entorhinal cortices--immunohistochemical studies. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. vol 59. issue 2. 2008-11-25. PMID:18622042. |
a search for colocalization of serotonin 5-ht2a and 5-ht1a receptors in the rat medial prefrontal and entorhinal cortices--immunohistochemical studies. |
2008-11-25 |
2023-08-12 |
rat |
| K Wedzony, A Chocyk, M Maćkowia. A search for colocalization of serotonin 5-HT2A and 5-HT1A receptors in the rat medial prefrontal and entorhinal cortices--immunohistochemical studies. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. vol 59. issue 2. 2008-11-25. PMID:18622042. |
recently developed antipsychotic drugs ameliorating the negative symptoms of schizophrenia act not only on dopamine d2 receptors but also on serotonin 2a (5-ht2a) and 1a (5-ht1a) receptors in specific regions of the cerebral cortex. |
2008-11-25 |
2023-08-12 |
rat |
| K Wedzony, A Chocyk, M Maćkowia. A search for colocalization of serotonin 5-HT2A and 5-HT1A receptors in the rat medial prefrontal and entorhinal cortices--immunohistochemical studies. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. vol 59. issue 2. 2008-11-25. PMID:18622042. |
since it is not yet known whether serotonin 5-ht1a and 5-ht2a receptors coexist in the same population of neurons in the cortex, the present study investigated their colocalization in the rat medial prefrontal (mpc) and entorhinal (ec) cortices. |
2008-11-25 |
2023-08-12 |
rat |
| K Wedzony, A Chocyk, M Maćkowia. A search for colocalization of serotonin 5-HT2A and 5-HT1A receptors in the rat medial prefrontal and entorhinal cortices--immunohistochemical studies. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. vol 59. issue 2. 2008-11-25. PMID:18622042. |
using antibodies that recognize epitopes specific to the serotonin 5-ht2a or 5-ht1a receptors, studies employing confocal microscopy have shown that in the mpc 5-ht2a receptors are preferentially, if not exclusively, present on the pyramidal neurons and that 5-ht1a-immunopositive material is present in the axonal hillocks and, to lower extend, in cytoplasm of presumably pyramidal cell bodies. |
2008-11-25 |
2023-08-12 |
rat |
| K Wedzony, A Chocyk, M Maćkowia. A search for colocalization of serotonin 5-HT2A and 5-HT1A receptors in the rat medial prefrontal and entorhinal cortices--immunohistochemical studies. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. vol 59. issue 2. 2008-11-25. PMID:18622042. |
present in shafts and axonal hillocks) we found that about 38% of neurons positive for the presence of serotonin 5-ht2a receptors, are also positive for serotonin 5-ht1a receptors in the mpc. |
2008-11-25 |
2023-08-12 |
rat |
| K Wedzony, A Chocyk, M Maćkowia. A search for colocalization of serotonin 5-HT2A and 5-HT1A receptors in the rat medial prefrontal and entorhinal cortices--immunohistochemical studies. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. vol 59. issue 2. 2008-11-25. PMID:18622042. |
in the ec, only 22% of serotonin 5-ht2a-positive neurons were positive for serotonin 5-ht1a receptor-immunoreactivity. |
2008-11-25 |
2023-08-12 |
rat |
| K Wedzony, A Chocyk, M Maćkowia. A search for colocalization of serotonin 5-HT2A and 5-HT1A receptors in the rat medial prefrontal and entorhinal cortices--immunohistochemical studies. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. vol 59. issue 2. 2008-11-25. PMID:18622042. |
in the respect of cytoplasmatic serotonin 5-ht1a receptor-immunoreactivity (possibly inactive receptors), 65% and 73% of serotonin 5-ht2a receptor-positive neurons were colocalized with serotonin 5-ht1a receptors in the mpc and ec, respectively. |
2008-11-25 |
2023-08-12 |
rat |
| K Wedzony, A Chocyk, M Maćkowia. A search for colocalization of serotonin 5-HT2A and 5-HT1A receptors in the rat medial prefrontal and entorhinal cortices--immunohistochemical studies. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. vol 59. issue 2. 2008-11-25. PMID:18622042. |
data obtained on serotonin 5-ht2a and 5-ht1a receptor localization provide anatomical grounds for at least three distinct populations of pyramidal neurons, one governed only by 5-ht2a, one only by 5-ht1a and one by both types of serotonin receptors. |
2008-11-25 |
2023-08-12 |
rat |
| Matthew A Cooper, Kathleen E McIntyre, Kim L Huhma. Activation of 5-HT1A autoreceptors in the dorsal raphe nucleus reduces the behavioral consequences of social defeat. Psychoneuroendocrinology. vol 33. issue 9. 2008-11-25. PMID:18692968. |
these data support the hypothesis that the activity of 5-ht cells in the drn, as regulated by 5-ht1a autoreceptors, contributes to the formation and display of conditioned defeat. |
2008-11-25 |
2023-08-12 |
Not clear |
| Zofia Rogó. Effect of repeated co-treatment with imipramine and metyrapone on the behavioral reactivity of the central serotonin, dopamine and alpha 1-adrenergic systems in rats. Pharmacological reports : PR. vol 59. issue 5. 2008-11-18. PMID:18048960. |
the aim of present study was to examine the effect of repeated co-treatment with imipramine and metyrapone on the development of adaptive changes in the function of central serotonin 5-ht1a and 5-ht2a, dopamine d2/3 and alpha 1-adrenergic receptors in rats. |
2008-11-18 |
2023-08-12 |
rat |
| Yukihiro Ohno, Saki Shimizu, Junta Imaki, Shizuka Ishihara, Nobumasa Sofue, Masashi Sasa, Yoshiko Kawa. Evaluation of the antibradykinetic actions of 5-HT1A agonists using the mouse pole test. Progress in neuro-psychopharmacology & biological psychiatry. vol 32. issue 5. 2008-11-05. PMID:18495311. |
the alleviation of haloperidol-induced bradykinesia by 8-oh-dpat was completely antagonized by way-100135 (a selective 5-ht1a antagonist), but was unaffected by cerebral 5-ht depletion with p-chlorophenylalanine (pcpa) treatment (300 mg/kg, i.p. |
2008-11-05 |
2023-08-12 |
mouse |
| Moshe Rav-Acha, Hagai Bergman, Yosef Yaro. Pre- and postsynaptic serotoninergic excitation of globus pallidus neurons. Journal of neurophysiology. vol 100. issue 2. 2008-11-05. PMID:18550726. |
analyzing the effects of specific 5-ht agonists and antagonists on the firing rate of gp neurons showed that the increase in firing rate is due to the activation of 5-ht1b and 5-ht1a receptors. |
2008-11-05 |
2023-08-12 |
rat |
| Moshe Rav-Acha, Hagai Bergman, Yosef Yaro. Pre- and postsynaptic serotoninergic excitation of globus pallidus neurons. Journal of neurophysiology. vol 100. issue 2. 2008-11-05. PMID:18550726. |
postsynaptically, serotonin activates a hyperpolarization-activated cation channel, probably via 5-ht1a receptors. |
2008-11-05 |
2023-08-12 |
rat |
| Maureen L Petrunich, Francisca Garcia, Gonzalo A Carrasco, George Battagli. Prolonged 5-HT1A/5-HT2A receptor cross-talk is absent prior to adulthood in rats. Neuroreport. vol 19. issue 15. 2008-11-03. PMID:18797297. |
in adult rats, serotonin 1a (5-ht1a) receptor activation produces heterologous desensitization of serotonin 2a (5-ht2a) neuroendocrine function at 1 h that persists up to 72 h. this study determined whether prolonged 5-ht1a/5-ht2a cross-talk exists before sexual maturation. |
2008-11-03 |
2023-08-12 |
rat |
| J W Brown, E A Sirlin, A M Benoit, J M Hoffman, R A Darnal. Activation of 5-HT1A receptors in medullary raphé disrupts sleep and decreases shivering during cooling in the conscious piglet. American journal of physiology. Regulatory, integrative and comparative physiology. vol 294. issue 3. 2008-10-31. PMID:18094064. |
we previously showed in conscious piglets that activation of 5-ht1a receptors with (+/-)-8-hydroxy-2-(dipropylamino)-tetralin (8-oh-dpat) in the paragigantocellularis lateralis (pgcl), a medullary region lateral to the raphé that contains substantial numbers of 5-ht neurons, eliminates rapid eye movement (rem) sleep and decreases shivering in a cold environment, but does not attenuate peripheral vasoconstriction. |
2008-10-31 |
2023-08-12 |
Not clear |