| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Tongjun Ma, Chenyu Li, Zeyin Nie, Huachun Miao, Feng W. Regulatory effect of electroacupuncture on hypothalamic serotonin and its receptor in rats with cerebral ischemia. Current neurovascular research. 2023-06-13. PMID:37309759. |
5-hydroxytryptamine (5-ht)/ 5-ht transporter (5-htt) and 5-ht receptor 2a (5-ht2a) are important in the treatment of cerebrovascular diseases. |
2023-06-13 |
2023-08-14 |
rat |
| Yuxiao Chen, Jie Sun, Zhen Yang, Hongyan B. Efficacy and safety of negative allosteric modulators of 5-hydroxytryptamine 2A receptors in the treatment of Alzheimer's disease psychosis: A systematic review and meta-analysis. Advances in clinical and experimental medicine : official organ Wroclaw Medical University. 2023-05-11. PMID:37166012. |
the 5-hydroxytryptamine (5-ht2a) receptors are located postsynaptically to serotonergic neurons in the frontal cortex and mediate both excitatory and inhibitory neurotransmissions. |
2023-05-11 |
2023-08-14 |
Not clear |
| Sandeep Singh, Alexander Botvinnik, Orr Shahar, Gilly Wolf, Corel Yakobi, Michal Saban, Adham Salama, Amit Lotan, Bernard Lerer, Tzuri Lifschyt. Effect of psilocybin on marble burying in ICR mice: role of 5-HT1A receptors and implications for the treatment of obsessive-compulsive disorder. Translational psychiatry. vol 13. issue 1. 2023-05-10. PMID:37164956. |
on this background, we set out to explore (1) the role of serotonin 2a (5-ht2a) and serotonin 1a (5-ht1a) receptors in the effect of psilocybin on marble burying; (2) the effect of staggered versus bolus psilocybin administration and persistence of the effect; (3) the effect of the 5-ht1a partial agonist, buspirone, on marble-burying and the head twitch response (htr) induced by psilocybin, a rodent correlate of psychedelic effects. |
2023-05-10 |
2023-08-14 |
mouse |
| Jignesh H Kamadar, D Roza Kumari, Khushal M Kapadiy. Recent Studies on Serotonin 5-HT2A Receptor Antagonists in Medicinal Chemistry: A Last Decades Survey. Mini reviews in medicinal chemistry. 2023-05-09. PMID:37157202. |
recent studies on serotonin 5-ht2a receptor antagonists in medicinal chemistry: a last decades survey. |
2023-05-09 |
2023-08-14 |
human |
| Jignesh H Kamadar, D Roza Kumari, Khushal M Kapadiy. Recent Studies on Serotonin 5-HT2A Receptor Antagonists in Medicinal Chemistry: A Last Decades Survey. Mini reviews in medicinal chemistry. 2023-05-09. PMID:37157202. |
one of the members of gpcrs is the serotonin 2a (5-ht2a) receptor, which has been associated with complex etiological mental illnesses. |
2023-05-09 |
2023-08-14 |
human |
| Akihito Takeda, Mao Fujita, Kengo Funakosh. Distribution of 5HT Receptors During the Regeneration Process After Spinal Cord Transection in Goldfish. Journal of chemical neuroanatomy. 2023-04-29. PMID:37119932. |
5ht2a was expressed at the luminal surface, suggesting that it is receptive to 5ht in the cerebrospinal fluid. |
2023-04-29 |
2023-08-14 |
Not clear |
| Ewa Ferensztajn-Rochowiak, Monika Dmitrzak-Węglarz, Aleksandra Szczepankiewicz, Maria Skibińska, Sebastian Kliwicki, Agnieszka Permoda-Pachuta, Aleksandra Suwalska, Piotr Czerski, Joanna Pawlak, Joanna Hause. Studies on candidate genes for lithium prophylaxis performed at the Poznan University of Medical Sciences. Psychiatria polska. vol 56. issue 5. 2023-04-19. PMID:37074853. |
the associations with lithium prophylactic efficacy were found for the polymorphisms in 5htt, acp1, arntl, bdnf, comt, drd1, fkbp5, fyn, glcc, nr3c1, and tim, genes, but not those in 5ht2a, 5ht2c, drd2, drd3, drd4, grin2b, gsk-3β, mmp-9, and ntrk2 genes. |
2023-04-19 |
2023-08-14 |
Not clear |
| Octavian Vasili. The pharmacogenetics of the new-generation antipsychotics - A scoping review focused on patients with severe psychiatric disorders. Frontiers in psychiatry. vol 14. 2023-03-06. PMID:36873203. |
allelic variability in genes encoding dopamine d2, d3, and serotonin, 5ht2a, 5ht2c receptors, comt, bdnf, and dopamine transporter dat1 was also associated with different adverse events or variations in the clinical efficacy of aripiprazole. |
2023-03-06 |
2023-08-14 |
Not clear |
| b' Jelena Nikoli\\xc4\\x87, Katarina Vukojevi\\xc4\\x87, Violeta \\xc5\\xa0olji\\xc4\\x87, Josip Mi\\xc5\\xa1kovi\\xc4\\x87, Martina Orlovi\\xc4\\x87 Vlaho, Mirna Saraga-Babi\\xc4\\x87, Natalija Filipovi\\xc4\\x8. Expression Patterns of Serotonin Receptors 5-HT1A, 5-HT2A, and 5-HT3A during Human Fetal Lung Development. International journal of molecular sciences. vol 24. issue 3. 2023-02-11. PMID:36769290.' |
expression patterns of serotonin receptors 5-ht1a, 5-ht2a, and 5-ht3a during human fetal lung development. |
2023-02-11 |
2023-08-14 |
human |
| b' Jelena Nikoli\\xc4\\x87, Katarina Vukojevi\\xc4\\x87, Violeta \\xc5\\xa0olji\\xc4\\x87, Josip Mi\\xc5\\xa1kovi\\xc4\\x87, Martina Orlovi\\xc4\\x87 Vlaho, Mirna Saraga-Babi\\xc4\\x87, Natalija Filipovi\\xc4\\x8. Expression Patterns of Serotonin Receptors 5-HT1A, 5-HT2A, and 5-HT3A during Human Fetal Lung Development. International journal of molecular sciences. vol 24. issue 3. 2023-02-11. PMID:36769290.' |
we analyzed the expression of the serotonin receptors 5-ht1a, 5-ht2a, and 5-ht3a at four different stages of fetal lung development from 12 to 40 weeks of gestation, divided into four groups: the pseudoglandular stage (12-16th week of development; |
2023-02-11 |
2023-08-14 |
human |
| Jiaqi Jin, Fan Xu, Yuxin Zhang, Jing Guan, Jihua F. Myocardial ischemia-reperfusion injury is probably due to the excessive production of mitochondrial ROS caused by the activation of 5-HT degradation system mediated by PAF receptor. Molecular immunology. vol 155. 2023-01-22. PMID:36682136. |
previously, we revealed a crucial role of 5-ht degradation system (5ds), consisting of 5-ht2a receptor (5-ht2ar), 5-ht synthases and monoamine oxidase a (mao-a), in ischemia-reperfusion (ir)-caused organ injury. |
2023-01-22 |
2023-08-14 |
Not clear |
| Bin Wang, Lu Cui, Qingqing Song, Moyan Liu, Jiao Kou, Shiqiang Sun, Hui Chen, Yahui Shi, Zhenlong Wu, Zhaolai Da. Excessive dietary L-tryptophan regulated amino acids metabolism and serotonin signaling in the colon of weaning piglets with acetate-induced gut inflammation. Amino acids. 2023-01-17. PMID:36648538. |
trp restored (p < 0.05) acetate-induced increase in concentrations of free aspartate, glutamate/glutamine, glycine, 5-ht, and 3-methylindole in the colon, downregulation of zonula occludens-1 and 5-ht reuptake transporter (sert) expression and upregulation of il-1β, il-8, tlr4, and 5-ht receptor 2a (htr2a) expression, and the increase in ratios of p-stat3/ stat3 and p-p65/p65 in the colon. |
2023-01-17 |
2023-08-14 |
Not clear |
| P Campos-Bedolla, E G Torrejón-González, D Mendoza-Mejía, M H Vargas, P Segura-Medina, V Carbajal-Salinas, A Rodríguez-Márquez, A Valeria Martínez-Silv. Role of 5-HT2 receptors family in the allergy-induced increased aorta contractile responses to 5-HT. Physiological research. 2022-12-22. PMID:36545875. |
we found that tcb-2 (5-ht2a agonist) and way161503 (5-ht2c agonist) induced aorta contractions resembling those elicited by 5-ht but less intense (~43% and ~25%, respectively). |
2022-12-22 |
2023-08-14 |
Not clear |
| P Campos-Bedolla, E G Torrejón-González, D Mendoza-Mejía, M H Vargas, P Segura-Medina, V Carbajal-Salinas, A Rodríguez-Márquez, A Valeria Martínez-Silv. Role of 5-HT2 receptors family in the allergy-induced increased aorta contractile responses to 5-HT. Physiological research. 2022-12-22. PMID:36545875. |
in conclusion, we found that allergic sensitization increased the aorta contractile responses to 5-ht, partly mediated by enhanced responses of 5-ht2a receptors, which was unrelated to changes in the expression of these receptors. |
2022-12-22 |
2023-08-14 |
Not clear |
| João P F Kurita, Anderson H F F Leão, Vinicius S Bioni, Raphael Wuo-Silva, Alvaro C Lima, Murilo A Paiva-Santos, Gabriela F Marinho, Débora M G Cunha, Marcela Becegato, Leonardo B Lopes-Silva, Alessandra M Ribeiro, Regina H Silv. Memory and anxiety-like behavior of rats in the plus-maze discriminative avoidance task: Role of serotonergic transmission in the basolateral amygdala. Behavioral neuroscience. 2022-12-22. PMID:36548050. |
the results showed that an increase in serotonin (5-ht) availability or the blockade of 5ht1a and 5ht2a bla receptors impaired aversive memory formation. |
2022-12-22 |
2023-08-14 |
rat |
| Allyson S Munneke, Tuhin S Chakraborty, Saige S Porter, Christi M Gendron, Scott D Pletche. The serotonin receptor 5-HT2A modulates lifespan and protein feeding in Frontiers in aging. vol 3. 2022-12-19. PMID:36531741. |
the serotonin receptor 5-ht2a modulates lifespan and protein feeding in the conserved neurotransmitter serotonin has been shown to be an important modulator of lifespan in specific nutritional contexts; however, it remained unclear how serotonin signaling influences lifespan under normal conditions. |
2022-12-19 |
2023-08-14 |
Not clear |
| Allyson S Munneke, Tuhin S Chakraborty, Saige S Porter, Christi M Gendron, Scott D Pletche. The serotonin receptor 5-HT2A modulates lifespan and protein feeding in Frontiers in aging. vol 3. 2022-12-19. PMID:36531741. |
here, we show that serotonin signaling through the 5-ht2a receptor influences lifespan, behavior, and physiology in |
2022-12-19 |
2023-08-14 |
Not clear |
| Orr Shahar, Alexander Botvinnik, Noam Esh-Zuntz, Michal Brownstien, Rachel Wolf, Amit Lotan, Gilly Wolf, Bernard Lerer, Tzuri Lifschyt. Role of 5-HT2A, 5-HT2C, 5-HT1A and TAAR1 Receptors in the Head Twitch Response Induced by 5-Hydroxytryptophan and Psilocybin: Translational Implications. International journal of molecular sciences. vol 23. issue 22. 2022-11-26. PMID:36430623. |
in rodents, the serotonin precursor, 5-hydroxytryptophan (5-htp) and psilocybin induce a characteristic 5-ht2a receptor (5-ht2ar)-mediated head twitch response (htr), which is correlated with the human psychedelic trip. |
2022-11-26 |
2023-08-14 |
mouse |
| Filiz İzci, Eda Ülger, Sinem Yolc. Manic Episode as a Result of Adding Trazodone to a Patient under Escitalopram Treatment. Alpha psychiatry. vol 22. issue 1. 2022-11-25. PMID:36426205. |
one of these is trazodone, which is an antidepressant that exhibits hypnotic effect by the effect of histamine h1 receptor antagonist and 5-ht2a stimulation, which is a serotonin transporter protein inhibitor and 5-ht2a and 5ht2c antagonist. |
2022-11-25 |
2023-08-14 |
Not clear |
| Elena Martín-González, Manuela Olmedo-Córdoba, Pilar Flores, Margarita Moreno-Montoy. Differential neurobiological markers in phenotype-stratified rats modeling high or low vulnerability to compulsive behavior: A narrative review. Current neuropharmacology. 2022-11-22. PMID:36411566. |
specifically, we reviewed preclinical studies on sip, that have assessed the effects of serotonergic, dopaminergic, and glutamatergic drugs; leading to the description of the neurobiological markers, such as the key role of the serotonin 5-ht2a receptor and glutamatergic signaling in a phenotype vulnerable to compulsivity as high drinker hd rats selected by sip. |
2022-11-22 |
2023-08-14 |
rat |