| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sheng-Huang Hsiao, Hsien-Hui Chung, Akio Inui, Yat-Ching Tong, Juei-Tang Chen. Inhibitory effect of 5-hydroxytryptamine on hyperphagia in mice with genetic overexpression of neuropeptide Y. Neuroscience letters. vol 394. issue 3. 2006-03-30. PMID:16332411. |
the npy-overexpressing mice were further divided into five groups: (1) control mice, (2) mice treated with 5-ht (5 mg/kg), (3) mice treated with 5-ht (5 mg/kg) and ketanserin (0.5 or 1 mg/kg), a 5-ht2a receptor antagonist, (4) mice treated with insulin (1 iu/kg), and (5) mice treated with insulin (1 iu/kg) and 5-ht (5 mg/kg). |
2006-03-30 |
2023-08-12 |
mouse |
| Sheng-Huang Hsiao, Hsien-Hui Chung, Akio Inui, Yat-Ching Tong, Juei-Tang Chen. Inhibitory effect of 5-hydroxytryptamine on hyperphagia in mice with genetic overexpression of neuropeptide Y. Neuroscience letters. vol 394. issue 3. 2006-03-30. PMID:16332411. |
in conclusion, 5-ht reduces hyperphagia in the npy-overexpressing rat through action on 5-ht2a receptors and this hypophagic effect of 5-ht does not depend on the hyperglycemia. |
2006-03-30 |
2023-08-12 |
mouse |
| E Syvälahti, J Penttilä, H Majasuo, E-P Pälvimäki, A Laakso, J Hietal. Combined treatment with citalopram and buspirone: effects on serotonin 5-HT2A and 5-HT2C receptors in the rat brain. Pharmacopsychiatry. vol 39. issue 1. 2006-03-29. PMID:16453246. |
combined treatment with citalopram and buspirone: effects on serotonin 5-ht2a and 5-ht2c receptors in the rat brain. |
2006-03-29 |
2023-08-12 |
rat |
| Ennio Esposit. Serotonin-dopamine interaction as a focus of novel antidepressant drugs. Current drug targets. vol 7. issue 2. 2006-03-10. PMID:16475959. |
among the multiple classes of 5-ht receptors described in the central nervous system, much attention has been devoted to the role of 5-ht2 receptor family in the control of central dopaminergic activity, because of the moderate to dense localization of both transcript and protein for 5-ht2a and 5-ht2c receptors in the substantia nigra (sn) and ventral tegmental area (vta), as well as their terminal regions. |
2006-03-10 |
2023-08-12 |
human |
| Hader A Mansour, Michael E Talkowski, Joel Wood, Lora Pless, Mikhil Bamne, Kodavali V Chowdari, Michael Allen, Charles L Bowden, Joseph Calabrese, Rif S El-Mallakh, Andrea Fagiolini, Stephen V Faraone, Mark D Fossey, Edward S Friedman, Laszlo Gyulai, Peter Hauser, Terence A Ketter, Jennifer M Loftis, Lauren B Marangell, David J Miklowitz, Andrew A Nierenberg, Jayendra Patel, Gary S Sachs, Pamela Sklar, Jordan W Smoller, Michael E Thase, Ellen Frank, David J Kupfer, Vishwajit L Nimgaonka. Serotonin gene polymorphisms and bipolar I disorder: focus on the serotonin transporter. Annals of medicine. vol 37. issue 8. 2006-03-07. PMID:16338761. |
nevertheless, suggestive associations are available for the 5ht2a receptor and the serotonin transporter genes. |
2006-03-07 |
2023-08-12 |
Not clear |
| Michelle Landry, Mark Frasier, Zhuo Chen, Louis D Van De Kar, Yahong Zhang, Francisca Garcia, George Battagli. Fluoxetine treatment of prepubescent rats produces a selective functional reduction in the 5-HT2A receptor-mediated stimulation of oxytocin. Synapse (New York, N.Y.). vol 58. issue 2. 2006-03-06. PMID:16088947. |
this study investigated the effects of chronic fluoxetine treatment on 5-ht2a serotonin receptor-mediated neuroendocrine responses in young male rats. |
2006-03-06 |
2023-08-12 |
rat |
| Maria A Tikhonova, Alexander V Kulikov, Ekaterina I Lebedeva, Natalia N Barykina, Tamara G Amstislavskaya, Nina K Popov. On association between cortical 5-HT2A receptors and behavior in rats with experimental thyroid disturbances. Pharmacology, biochemistry, and behavior. vol 82. issue 3. 2006-03-02. PMID:16325897. |
the present study was aimed to reveal effects of chronic th deficit and excess on some types of adaptive behavior (catalepsy, acoustic startle reflex, open-field performance), sexual arousal and cerebral 5-ht2a serotonin receptors of adult wistar rats. |
2006-03-02 |
2023-08-12 |
rat |
| Yehoshua Gozes, Mahtab Moayeri, Jason F Wiggins, Stephen H Leppl. Anthrax lethal toxin induces ketotifen-sensitive intradermal vascular leakage in certain inbred mice. Infection and immunity. vol 74. issue 2. 2006-02-22. PMID:16428776. |
the leakage could be inhibited by ketotifen, an inhibitor of mast cell degranulation, but not by azelastine, a histamine receptor 1 antagonist, or by ketanserin, a serotonin 5-ht2a receptor antagonist. |
2006-02-22 |
2023-08-12 |
mouse |
| K Nishihira, A Yamashita, N Tanaka, R Kawamoto, T Imamura, R Yamamoto, T Eto, Y Asad. Inhibition of 5-hydroxytryptamine receptor prevents occlusive thrombus formation on neointima of the rabbit femoral artery. Journal of thrombosis and haemostasis : JTH. vol 4. issue 1. 2006-02-21. PMID:16409475. |
5-hydroxytryptamine (5-ht) is a potent vasoactive and platelet-aggregating substance that is predominantly mediated by 5-ht2a receptor. |
2006-02-21 |
2023-08-12 |
rabbit |
| Suzana Uzun, Oliver Kozumplik, Ninoslav Mimica, Vera Folnegović-Smal. Aripiprazole: an overview of a novel antipsychotic. Psychiatria Danubina. vol 17. issue 1-2. 2006-02-15. PMID:16395846. |
aripiprazole exhibits high affinity for dopamine d2 and d3, serotonin 5-ht1a and 5-ht2a receptors, moderate affinity for dopamine d4, serotonin 5-ht2c and 5-ht7, alpha1-adrenergic and histamine h1 receptors. |
2006-02-15 |
2023-08-12 |
Not clear |
| Regina P Szucs, Paul S Frankel, Lance R McMahon, Kathryn A Cunningha. Relationship of cocaine-induced c-Fos expression to behaviors and the role of serotonin 5-HT2A receptors in cocaine-induced c-Fos expression. Behavioral neuroscience. vol 119. issue 5. 2006-02-14. PMID:16300424. |
relationship of cocaine-induced c-fos expression to behaviors and the role of serotonin 5-ht2a receptors in cocaine-induced c-fos expression. |
2006-02-14 |
2023-08-12 |
rat |
| Regina P Szucs, Paul S Frankel, Lance R McMahon, Kathryn A Cunningha. Relationship of cocaine-induced c-Fos expression to behaviors and the role of serotonin 5-HT2A receptors in cocaine-induced c-Fos expression. Behavioral neuroscience. vol 119. issue 5. 2006-02-14. PMID:16300424. |
serotonin 5-ht2a receptor antagonists have been shown to attenuate the locomotor stimulant effects of cocaine in rats. |
2006-02-14 |
2023-08-12 |
rat |
| René Hurlemann, Andreas Matusch, Simon B Eickhoff, Nicola Palomero-Gallagher, Philipp T Meyer, Christian Boy, Wolfgang Maier, Karl Zilles, Katrin Amunts, Andreas Baue. Analysis of neuroreceptor PET-data based on cytoarchitectonic maximum probability maps: a feasibility study. Anatomy and embryology. vol 210. issue 5-6. 2006-02-10. PMID:16187140. |
in this feasibility study, we used 5-hydroxytryptamine 2a (5-ht2a) receptor pet to test the applicability of maximum cytoarchitectonic probability maps for quantitative analysis. |
2006-02-10 |
2023-08-12 |
human |
| Pierre Blier, Steve T Szab. Potential mechanisms of action of atypical antipsychotic medications in treatment-resistant depression and anxiety. The Journal of clinical psychiatry. vol 66 Suppl 8. 2006-02-10. PMID:16336034. |
in contrast, blocking 5-ht2a receptors in the presence of serotonin reuptake inhibition using the experimental compound ym992 enhances both serotonin and norepinephrine release. |
2006-02-10 |
2023-08-12 |
Not clear |
| Valquíria Camin de Bortoli, Regina Lúcia Nogueira, Hélio Zangross. Effects of fluoxetine and buspirone on the panicolytic-like response induced by the activation of 5-HT1A and 5-HT2A receptors in the rat dorsal periaqueductal gray. Psychopharmacology. vol 183. issue 4. 2006-01-31. PMID:16258751. |
administration of 5-hydroxytryptamine (5-ht)1a and 5-ht2a receptor agonists into the dorsal periaqueductal gray (dpag) inhibits escape, a defensive behavior associated with panic attacks. |
2006-01-31 |
2023-08-12 |
rat |
| Taketoshi Ogawa, Atsuhiro Sugidachi, Naoki Tanaka, Koichi Fujimoto, Jun-ichiro Fukushige, Yoshiro Tani, Fumitoshi Asa. Effects of R-102444 and its active metabolite R-96544, selective 5-HT2A receptor antagonists, on experimental acute and chronic pancreatitis: Additional evidence for possible involvement of 5-HT2A receptors in the development of experimental pancreatitis. European journal of pharmacology. vol 521. issue 1-3. 2006-01-25. PMID:16183055. |
the effects of r-102444 ((2r, 4r)-4-lauroyloxy-2-[2-[2-[2-(3-methoxy)phenyl]ethyl]phenoxy]ethyl-1-methylpyrrolidine hydrochloride) and its active metabolite r-96544 ((2r, 4r)-2-[2-[2-[2-(3-methoxy)phenyl]ethyl]phenoxy]ethyl-4-hydroxy-1-methylpyrrolidine hydrochloride), potent and selective 5-hydroxytryptamine 2a (5-ht2a) receptor antagonists, on development of pancreatitis were investigated in experimental models of acute and chronic pancreatitis. |
2006-01-25 |
2023-08-12 |
mouse |
| b' Pascal Amireault, Fran\\xc3\\xa7ois Dub\\xc3\\xa. Intracellular cAMP and calcium signaling by serotonin in mouse cumulus-oocyte complexes. Molecular pharmacology. vol 68. issue 6. 2006-01-19. PMID:16131615.' |
as measured with cumulus cells preloaded with fura-2/acetoxymethyl ester (am), the addition of 5-ht also caused dose-dependent ca2+ increases, which were probably linked to detected 5-ht2a and 5-ht2b receptors. |
2006-01-19 |
2023-08-12 |
mouse |
| b' Pascal Amireault, Fran\\xc3\\xa7ois Dub\\xc3\\xa. Intracellular cAMP and calcium signaling by serotonin in mouse cumulus-oocyte complexes. Molecular pharmacology. vol 68. issue 6. 2006-01-19. PMID:16131615.' |
our results show that 5-ht may be a local regulator in mouse cumulus-oocyte complexes through its actions on camp and ca2+ signaling, as mediated by 5-ht2a, 5-ht2b, and 5-ht7 receptors. |
2006-01-19 |
2023-08-12 |
mouse |
| Kyoji Morita, Hideki Arimochi, Song He. Serotonergic 5-HT2A receptor stimulation induces steroid 5alpha-reductase gene expression in rat C6 glioma cells via transcription factor Egr-1. Brain research. Molecular brain research. vol 139. issue 2. 2006-01-17. PMID:15936112. |
serotonin elevated 5alpha-r mrna and protein levels through the stimulation of serotonin 5-ht2a receptors, and also elevated egr-1 mrna and protein levels prior to 5alpha-r gene expression in the glioma cells. |
2006-01-17 |
2023-08-12 |
rat |
| Yasuhiro Kawakami, Yoshihisa Kitamura, Hiroaki Araki, Kouhei Kitagawa, Katsuya Suemaru, Kazuhiko Shibata, Yutaka Gomit. Effects of monoamine reuptake inhibitors on wet-dog shakes mediated by 5-HT2A receptors in ACTH-treated rats. Pharmacology, biochemistry, and behavior. vol 81. issue 1. 2005-12-30. PMID:15894065. |
we examined the influence of imipramine, a serotonin (5-ht) and noradrenaline (na) reuptake inhibitor, desipramine, a na reuptake inhibitor, bupropion, a dopamine reuptake inhibitor, fluvoxamine, a selective 5-ht reuptake inhibitor, and mazindol, a catecholamine reuptake inhibitor, on a 5-ht2a receptor-mediated behavior, (+/-)-1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (doi)-induced wet-dog shakes, in naive and adrenocorticotropic hormone (acth)-treated rats. |
2005-12-30 |
2023-08-12 |
rat |