| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| F Chaoulof. Regulation of 5-HT receptors by corticosteroids: where do we stand? Fundamental & clinical pharmacology. vol 9. issue 3. 1995-11-21. PMID:7557817. |
among the dozen of 5-ht receptors identified so far, four receptors (namely the 5-ht1a, 5-ht1b, 5-ht2a, and 5-ht2c receptors)--and the 5-ht uptake system--have been the focus of studies aimed at detecting corticosteroid modulatory effects. |
1995-11-21 |
2023-08-12 |
rat |
| F Chaoulof. Regulation of 5-HT receptors by corticosteroids: where do we stand? Fundamental & clinical pharmacology. vol 9. issue 3. 1995-11-21. PMID:7557817. |
however, because the data regarding a corticosteroid control of other 5-ht receptors are either scarce and contradictory (eg 5-ht1b, 5-ht2a, 5-ht2c receptors and 5-ht uptake systems) or lacking, it is at the present time unknown whether corticosteroids exert other effects on 5-ht receptor-mediated functions, including those related to homeostasis. |
1995-11-21 |
2023-08-12 |
rat |
| M R Briejer, L M Akkermans, R A Lefebvre, J A Schuurke. Novel 5-HT2-like receptor mediates neurogenic relaxation of the guinea-pig proximal colon. European journal of pharmacology. vol 279. issue 2-3. 1995-11-06. PMID:7556392. |
after blockade of 5-ht2a, 5-ht3 and 5-ht4 receptor-mediated contractions, 5-hydroxytryptamine (5-ht) induced relaxations yielding a biphasic concentration-response curve. |
1995-11-06 |
2023-08-12 |
Not clear |
| A Dalpiaz, S Gessi, P A Borea, G Gill. Binding thermodynamics of serotonin to rat-brain 5-HT1A, 5HT2A and 5-HT3 receptors. Life sciences. vol 57. issue 12. 1995-10-19. PMID:7674802. |
binding thermodynamics of serotonin to rat-brain 5-ht1a, 5ht2a and 5-ht3 receptors. |
1995-10-19 |
2023-08-12 |
rat |
| A Dalpiaz, S Gessi, P A Borea, G Gill. Binding thermodynamics of serotonin to rat-brain 5-HT1A, 5HT2A and 5-HT3 receptors. Life sciences. vol 57. issue 12. 1995-10-19. PMID:7674802. |
the thermodynamic parameters delta g degrees, delta h degrees and delta s degrees of the binding equilibrium of serotonin to 5-ht1a, 5-ht2a and 5-ht3 rat-brain membrane receptors have been determined by means of affinity constant measurements at six temperatures in the range 0 -35 degrees c and van't hoff plots. |
1995-10-19 |
2023-08-12 |
rat |
| J C Poblete, E C Azmiti. Activation of glycogen phosphorylase by serotonin and 3,4-methylenedioxymethamphetamine in astroglial-rich primary cultures: involvement of the 5-HT2A receptor. Brain research. vol 680. issue 1-2. 1995-10-10. PMID:7663989. |
activation of glycogen phosphorylase by serotonin and 3,4-methylenedioxymethamphetamine in astroglial-rich primary cultures: involvement of the 5-ht2a receptor. |
1995-10-10 |
2023-08-12 |
rat |
| G Griebe. 5-Hydroxytryptamine-interacting drugs in animal models of anxiety disorders: more than 30 years of research. Pharmacology & therapeutics. vol 65. issue 3. 1995-09-19. PMID:7644567. |
more than 1300 experiments were carried out in this area and they provide evidence that: (1) results obtained in ethologically based animal models of anxiety with drugs stimulating 5-ht transmission are most consistent with the classic 5-ht hypothesis of anxiety in that they show an increase in animals' emotional reactivity; (2) no category of anti-anxiety models are selectively sensitive to the anxiolytic-like effects of drugs targetting 5-ht1a, 5-ht2a or 5-ht2c receptor subtypes; (3) anxiolytic-like effects of 5-ht3 receptor antagonists, in the great part, are revealed by models based on spontaneous behaviors. |
1995-09-19 |
2023-08-12 |
Not clear |
| H Hirano, J Day, H C Fibige. Serotonergic regulation of acetylcholine release in rat frontal cortex. Journal of neurochemistry. vol 65. issue 3. 1995-09-18. PMID:7643092. |
in contrast, the serotonin 5-ht2a receptor antagonist ketanserin (5 mg/kg, i.p.) |
1995-09-18 |
2023-08-12 |
rat |
| H Hirano, J Day, H C Fibige. Serotonergic regulation of acetylcholine release in rat frontal cortex. Journal of neurochemistry. vol 65. issue 3. 1995-09-18. PMID:7643092. |
in contrast to previous studies that have concluded that serotonin has inhibitory actions on cortical acetylcholine release, the present results indicate that fenfluramine increases cortical acetylcholine release in vivo by its ability to enhance serotonin transmission and that serotonin produces these effects at least in part via actions at serotonin 5-ht2a receptors. |
1995-09-18 |
2023-08-12 |
rat |
| M R Briejer, L M Akkermans, J A Schuurke. Interactions of serotonin with multiple receptors and neurotransmitters in the guinea-pig isolated colon. Archives internationales de pharmacodynamie et de therapie. vol 329. issue 1. 1995-09-14. PMID:7639614. |
by means of the neurotoxin, tetrodotoxin, the muscarinic cholinoceptor antagonist, atropine, and selective 5-ht receptor antagonists, it was shown that the contractions to 5-ht are mediated by 5-ht2a receptors, localized on the smooth muscle, and by 5-ht3 and 5-ht4 receptors, localized on cholinergic nerves. |
1995-09-14 |
2023-08-12 |
Not clear |
| B E Summer, G Fin. Estrogen increases the density of 5-hydroxytryptamine(2A) receptors in cerebral cortex and nucleus accumbens in the female rat. The Journal of steroid biochemistry and molecular biology. vol 54. issue 1-2. 1995-09-08. PMID:7632610. |
based on our finding that estradiol selectively stimulates the expression of 5-hydroxytryptamine(2a) (5-ht2a) receptor mrna in the dorsal raphe nucleus of the female rat, we investigated the effects of estradiol on the density of 5-ht2a receptors in brain. |
1995-09-08 |
2023-08-12 |
rat |
| M R Briejer, G J Veen, L M Akkermans, R A Lefebvre, J A Schuurke. Cisapride and structural analogs selectively enhance 5-hydroxytryptamine (5-HT)-induced purinergic neurotransmission in the guinea pig proximal colon. The Journal of pharmacology and experimental therapeutics. vol 274. issue 2. 1995-09-08. PMID:7636723. |
in the continuous presence of ketanserin (0.3 microm) and tropisetron (3 microm) to block contractions via 5-ht2a, 5-ht3 and 5-ht4 receptors, 5-ht induced relaxations that yielded a biphasic concentration-response curve. |
1995-09-08 |
2023-08-12 |
Not clear |
| W X Shi, P Nathaniel, B S Bunne. Ritanserin, a 5-HT2A/2C antagonist, reverses direct dopamine agonist-induced inhibition of midbrain dopamine neurons. The Journal of pharmacology and experimental therapeutics. vol 274. issue 2. 1995-09-08. PMID:7636736. |
neither the selective 5-ht2a antagonist mdl 100907 nor depletion of endogenous 5-ht using p-chlorophenylalanine mimicked the effect of rit (i.e., attenuated quinpirole-induced inhibition). |
1995-09-08 |
2023-08-12 |
rat |
| J Yamada, Y Sugimoto, T Yoshikawa, I Kimura, K Horisak. The involvement of the peripheral 5-HT2A receptor in peripherally administered serotonin-induced hyperglycemia in rats. Life sciences. vol 57. issue 8. 1995-09-08. PMID:7637555. |
5-ht i.p.-induced hyperglycemia was strongly antagonized by the 5-ht2a receptor antagonist ketanserin. |
1995-09-08 |
2023-08-12 |
rat |
| J Yamada, Y Sugimoto, T Yoshikawa, I Kimura, K Horisak. The involvement of the peripheral 5-HT2A receptor in peripherally administered serotonin-induced hyperglycemia in rats. Life sciences. vol 57. issue 8. 1995-09-08. PMID:7637555. |
these results suggest that the hyperglycemic effects of 5-ht are closely related to the release of adrenaline from the adrenal gland, mediated by 5-ht2a receptors. |
1995-09-08 |
2023-08-12 |
rat |
| N Bonhomme, P De Deurwaèrdere, M Le Moal, U Spampinat. Evidence for 5-HT4 receptor subtype involvement in the enhancement of striatal dopamine release induced by serotonin: a microdialysis study in the halothane-anesthetized rat. Neuropharmacology. vol 34. issue 3. 1995-09-01. PMID:7543190. |
the effect induced by 1 microm 5-ht was not blocked by 10 microm (-)pindolol, a 5-ht1 receptor antagonist, 1 microm ketanserin or 10 microm cinanserin, both 5-ht2a antagonists. |
1995-09-01 |
2023-08-12 |
rat |
| I Sugihara, E J Lang, R Lliná. Serotonin modulation of inferior olivary oscillations and synchronicity: a multiple-electrode study in the rat cerebellum. The European journal of neuroscience. vol 7. issue 4. 1995-08-30. PMID:7620604. |
injections of various 5-ht agonists and antagonists demonstrated that a 5-ht type-2a (5-ht2a) receptor is the main mediator for the 5-ht effect, which was very similar to the effect produced by injections of harmaline. |
1995-08-30 |
2023-08-12 |
rat |
| I Sugihara, E J Lang, R Lliná. Serotonin modulation of inferior olivary oscillations and synchronicity: a multiple-electrode study in the rat cerebellum. The European journal of neuroscience. vol 7. issue 4. 1995-08-30. PMID:7620604. |
however, 5-ht and harmaline appear to have independent mechanisms since the action of harmaline was not blocked by the 5-ht2a antagonist ly53857. |
1995-08-30 |
2023-08-12 |
rat |
| S C Sealfon, L Chi, B J Ebersole, V Rodic, D Zhang, J A Ballesteros, H Weinstei. Related contribution of specific helix 2 and 7 residues to conformational activation of the serotonin 5-HT2A receptor. The Journal of biological chemistry. vol 270. issue 28. 1995-08-25. PMID:7622478. |
related contribution of specific helix 2 and 7 residues to conformational activation of the serotonin 5-ht2a receptor. |
1995-08-25 |
2023-08-12 |
Not clear |
| S Davis, D J Heal, S C Stanfor. Long-lasting effects of an acute stress on the neurochemistry and function of 5-hydroxytryptaminergic neurones in the mouse brain. Psychopharmacology. vol 118. issue 3. 1995-08-23. PMID:7617818. |
sibutramine, but not saline, reduced 5-ht synthesis and 5-ht2a receptor-mediated head-twitches 3 h after the swim and increased synthesis at 7 days. |
1995-08-23 |
2023-08-12 |
mouse |