| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Constanze Raltschev, Florian Hetsch, Aline Winkelmann, Jochen C Meier, Marcus Semtne. Electrophysiological Signature of Homomeric and Heteromeric Glycine Receptor Channels. The Journal of biological chemistry. vol 291. issue 34. 2017-05-12. PMID:27382060. |
thus, the alanine residue ala(254) determines voltage-dependent rectification upon receptor desensitization and reveals a physio-molecular signature of homomeric glycine receptor channels, which provides unprecedented opportunities for the identification of these channels at the single cell level. |
2017-05-12 |
2023-08-13 |
Not clear |
| Pedro A Sánchez-Murcia, Juan A Bueren-Calabuig, Marta Camacho-Artacho, Álvaro Cortés-Cabrera, Federico Gag. Stepwise Simulation of 3,5-Dihydro-5-methylidene-4H-imidazol-4-one (MIO) Biogenesis in Histidine Ammonia-lyase. Biochemistry. vol 55. issue 41. 2017-05-09. PMID:27682658. |
the consideration of the protein environment in our computations shows that water molecules, which have been mostly neglected in previous theoretical work, play a highly relevant role in the reaction mechanism and, more importantly, that backbone cyclization resulting from the nucleophilic attack of the gly amide lone pair on the π* orbital of the ala carbonyl precedes side-chain dehydration of the central serine. |
2017-05-09 |
2023-08-13 |
Not clear |
| Debashree Basudhar, Yarrow Madrona, Erik T Yukl, Santhosh Sivaramakrishnan, Clinton R Nishida, Pierre Moënne-Loccoz, Paul R Ortiz de Montellan. Distal Hydrogen-bonding Interactions in Ligand Sensing and Signaling by Mycobacterium tuberculosis DosS. The Journal of biological chemistry. vol 291. issue 31. 2017-05-08. PMID:27235395. |
mutation of glu-87 to ala or gly rendered the protein constitutively active as a kinase, but with lower autophosphorylation activity than the wild-type in the fe(ii) and the fe(ii)-co states, whereas the e87d mutant had little kinase activity except for the fe(ii)-no complex. |
2017-05-08 |
2023-08-13 |
Not clear |
| E J P Strang, M Eklund, P Rosenfelder, N Sauer, J K Htoo, R Mosenthi. Chemical composition and standardized ileal amino acid digestibility of eight genotypes of rye fed to growing pigs. Journal of animal science. vol 94. issue 9. 2017-04-24. PMID:27898917. |
for thr, ala, and gly, there were no differences in csid among the 8 rye genotypes. |
2017-04-24 |
2023-08-13 |
Not clear |
| Fenfen Lei, Qiangzhong Zhao, Lianzhu Lin, Baoguo Sun, Mouming Zha. Evaluation of the Hydrolysis Specificity of an Aminopeptidase from Bacillus licheniformis SWJS33 Using Synthetic Peptides and Soybean Protein Isolate. Journal of agricultural and food chemistry. vol 65. issue 1. 2017-04-21. PMID:27992209. |
the aminopeptidase showed high specificity for dipeptides with leu, val, ala, gly, and phe at the n-terminus, and the specificity was significantly affected by the nature of the penultimate residue. |
2017-04-21 |
2023-08-13 |
Not clear |
| Fenfen Lei, Qiangzhong Zhao, Lianzhu Lin, Baoguo Sun, Mouming Zha. Evaluation of the Hydrolysis Specificity of an Aminopeptidase from Bacillus licheniformis SWJS33 Using Synthetic Peptides and Soybean Protein Isolate. Journal of agricultural and food chemistry. vol 65. issue 1. 2017-04-21. PMID:27992209. |
in the hydrolysis of soy protein isolate, blam preferred peptides with leu, glu, gly, and ala at the n-terminus by free amino acid analysis and preferred peptides with leu, ala, ser, trp, and tyr at the n-terminus by uplc-ms/ms. |
2017-04-21 |
2023-08-13 |
Not clear |
| Ning Tang, Leif H Skibste. Calcium Binding to Amino Acids and Small Glycine Peptides in Aqueous Solution: Toward Peptide Design for Better Calcium Bioavailability. Journal of agricultural and food chemistry. vol 64. issue 21. 2017-04-05. PMID:27159329. |
at high ph, corresponding to conditions for calcium absorption, the binding affinity increased in the order lys < arg < cys < gln < gly ∼ ala < asn < his < leu < glu< asp. |
2017-04-05 |
2023-08-13 |
Not clear |
| Hongjie Lei, Huaide Xu, Li Feng, Zhimin Yu, Haifeng Zhao, Mouming Zha. Fermentation performance of lager yeast in high gravity beer fermentations with different sugar supplementations. Journal of bioscience and bioengineering. vol 122. issue 5. 2017-03-27. PMID:27329414. |
the excretion of gly and ala, and the absorption of pro in the later stage of fermentation were promoted by maltose supplementation. |
2017-03-27 |
2023-08-13 |
Not clear |
| Tingzhang Hu, Nong Zhou, Meiling Fu, Juan Qin, Xiaoyun Huan. Characterization of OsLEA1a and its inhibitory effect on the resistance of E. coli to diverse abiotic stresses. International journal of biological macromolecules. vol 91. 2017-03-10. PMID:27339321. |
oslea1a protein contains abundant of lys, ala, glu, asp, gly, arg and leu, but depleted in cys, his, phe, trp and tyr residues; and is strongly hydrophilic. |
2017-03-10 |
2023-08-13 |
Not clear |
| Zhao Jiang, Chang-Guo Yuan, Min Xiao, Xin-Peng Tian, Inam-Ullah Khan, Chang-Jin Kim, Xiao-Yang Zhi, Wen-Jun L. Abyssicoccus albus gen. nov., sp. nov., a novel member of the family Staphylococcaceae isolated from marine sediment of the Indian Ocean. Antonie van Leeuwenhoek. vol 109. issue 8. 2017-03-01. PMID:27272908. |
the cell wall amino acids were found to contain lys, ala, glu, gly, asp, ser and thr. |
2017-03-01 |
2023-08-13 |
Not clear |
| F Zehra Küçükbay, Hasan Küçükbay, Muhammet Tanc, Claudiu T Supura. Synthesis and carbonic anhydrase I, II, IV and XII inhibitory properties of N-protected amino acid - sulfonamide conjugates. Journal of enzyme inhibition and medicinal chemistry. vol 31. issue 6. 2017-02-27. PMID:26899532. |
n-protected amino acids (gly, ala and phe protected with boc and z groups) were reacted with sulfonamide derivatives, leading to the corresponding n-protected amino acid-sulfonamide conjugates. |
2017-02-27 |
2023-08-13 |
human |
| F Zehra Küçükbay, Hasan Küçükbay, Muhammet Tanc, Claudiu T Supura. Synthesis and carbonic anhydrase inhibitory properties of amino acid - coumarin/quinolinone conjugates incorporating glycine, alanine and phenylalanine moieties. Journal of enzyme inhibition and medicinal chemistry. vol 31. issue 6. 2017-02-21. PMID:26586254. |
n-protected amino acids (gly, ala and phe) were reacted with amino substituted coumarin and quinolinone derivatives, leading to the corresponding n-protected amino acid-coumarin/quinolinone conjugates. |
2017-02-21 |
2023-08-13 |
human |
| Qinglong Meng, Yanfei Zhang, Xiaozhi Ju, Chunling Ma, Hongwu Ma, Jiuzhou Chen, Ping Zheng, Jibin Sun, Jun Zhu, Yanhe Ma, Xueming Zhao, Tao Che. Production of 5-aminolevulinic acid by cell free multi-enzyme catalysis. Journal of biotechnology. vol 226. 2017-02-13. PMID:27012885. |
cheap substrates (succinate and glycine) were used for ala synthesis by two enzymes: 5-aminolevulinic acid synthase (alas) from laceyella sacchari (ls-alas) and succinyl-coa synthase (suc) from escherichia coli. |
2017-02-13 |
2023-08-13 |
Not clear |
| Shuli Liu, Guangming Zhang, Jianzheng Li, Xiangkun Li, Jie Zhan. Optimization of Biomass and 5-Aminolevulinic Acid Production by Rhodobacter sphaeroides ATCC17023 via Response Surface Methodology. Applied biochemistry and biotechnology. vol 179. issue 3. 2017-01-16. PMID:26875086. |
three additives were optimized, namely succinate and glycine that are precursors of ala biosynthesis, and d-glucose that is an inhibitor of ala dehydratase. |
2017-01-16 |
2023-08-13 |
Not clear |
| E Merlot, H Gilbert, N Le Floc'. Metabolic response to an inflammatory challenge in pigs divergently selected for residual feed intake. Journal of animal science. vol 94. issue 2. 2016-12-29. PMID:27065126. |
total aa, gln, ile, leu, pro ( < 0.05), and hydroxyproline ( = 0.07) were less in rfi than rfi pigs at fed state, whereas ala and gly were less in rfi pigs at fasted and fed states ( < 0.05). |
2016-12-29 |
2023-08-13 |
Not clear |
| Yongqing Hou, Kang Yao, Yulong Yin, Guoyao W. Endogenous Synthesis of Amino Acids Limits Growth, Lactation, and Reproduction in Animals. Advances in nutrition (Bethesda, Md.). vol 7. issue 2. 2016-12-13. PMID:26980816. |
eight aas (ala, asn, asp, glu, gln, gly, pro, and ser) are formed by all animals, whereas de novo synthesis of arg occurs in a species-specific manner in most mammals (e.g., humans, pigs, and rats). |
2016-12-13 |
2023-08-13 |
human |
| Agnes Czikora, Daniel J Lundberg, Adelle Abramovitz, Nancy E Lewin, Noemi Kedei, Megan L Peach, Xiaoling Zhou, Raymond C Merritt, Elizabeth A Craft, Derek C Braun, Peter M Blumber. Structural Basis for the Failure of the C1 Domain of Ras Guanine Nucleotide Releasing Protein 2 (RasGRP2) to Bind Phorbol Ester with High Affinity. The Journal of biological chemistry. vol 291. issue 21. 2016-12-13. PMID:27022025. |
replacing asn(7), ser(8), ala(19), and ile(21) with the corresponding residues from rasgrp1/3 (thr(7), tyr(8), gly(19), and leu(21), respectively) conferred potent binding affinity (kd = 1.47 ± 0.03 nm) in vitro and membrane translocation in response to phorbol 12-myristate 13-acetate in lncap cells. |
2016-12-13 |
2023-08-13 |
Not clear |
| K H Sabeena Farvin, Lisa Lystbæk Andersen, Jeanette Otte, Henrik Hauch Nielsen, Flemming Jessen, Charlotte Jacobse. Antioxidant activity of cod (Gadus morhua) protein hydrolysates: Fractionation and characterisation of peptide fractions. Food chemistry. vol 204. 2016-11-07. PMID:26988519. |
the free amino acids in all fractions were dominated by ala, gly, glu and ser. |
2016-11-07 |
2023-08-13 |
Not clear |
| Liuqin He, Li Wu, Zhiqi Xu, Tiejun Li, Kang Yao, Zhijie Cui, Yulong Yin, Guoyao W. Low-protein diets affect ileal amino acid digestibility and gene expression of digestive enzymes in growing and finishing pigs. Amino acids. vol 48. issue 1. 2016-11-02. PMID:26210756. |
growing pigs fed with the 12 % cp diet showed higher digestibilities for cp (p < 0.05), dm (p < 0.05), lys (p < 0.0001), met (p < 0.01), cys (p < 0.01), thr (p < 0.01), trp (p < 0.05), val (p < 0.05), phe (p < 0.05), ala (p < 0.05), cys (p < 0.01), and gly (p < 0.05) than those fed the 18 % cp diet. |
2016-11-02 |
2023-08-13 |
Not clear |
| Jiajun Wang, Shuli Chou, Lin Xu, Xin Zhu, Na Dong, Anshan Shan, Zhihui Che. High specific selectivity and Membrane-Active Mechanism of the synthetic centrosymmetric α-helical peptides with Gly-Gly pairs. Scientific reports. vol 5. 2016-10-24. PMID:26530005. |
therefore, here, we established a centrosymmetric α-helical sequence template (y + hhh + y)n (h, hydrophobic amino acid; +, cationic amino acid; y, gly or hydrophobic amino acid), which contributed to amphipathicity, and a series of centrosymmetric peptides was designed with pairs of small amino acids (ala and gly), which were utilized to modulate the biological activity. |
2016-10-24 |
2023-08-13 |
Not clear |