| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| TuAnh Ngoc Huynh, Hsia-Yin Lin, Chris E Noriega, Alice V Lin, Valley Stewar. Cross Talk Inhibition Nullified by a Receiver Domain Missense Substitution. Journal of bacteriology. vol 197. issue 20. 2015-12-17. PMID:26260457. |
most receiver domain sequences contain a small residue (gly or ala) at position t + 1 just distal to the essential thr or ser residue that forms part of the active site. |
2015-12-17 |
2023-08-13 |
Not clear |
| Qing Ye, Shi-Qiang Shang, Wei L. A new vaccine escape mutant of hepatitis B virus causes occult infection. Human vaccines & immunotherapeutics. vol 11. issue 2. 2015-12-15. PMID:25692622. |
the sequencing data of s coding regions shows that patient x has been infected by a new hbv variant with an a to c substitution at nt431, resulting in an asp(gac)to ala(gcc) substitution at aa144 of major protein; cc to aa substitution at nt359 and nt360, resulting in an pro(ccc) to gln(caa) substitution at aa120 of pre "a" epitope; a to g substitution at nt491, resulting in an glu(gag) to gly(ggg) substitution at aa164 of post "a" epitope. |
2015-12-15 |
2023-08-13 |
Not clear |
| Wei He, Ming Liu, Xiaonan Huang, Zuhong Qing, Wei Ga. The influence of vitamin D receptor genetic variants on bone mineral density and osteoporosis in Chinese postmenopausal women. Disease markers. vol 2015. 2015-12-08. PMID:25784778. |
our data indicated that the vdr p.glicine (gly)14 alanine (ala) and p.histidine (his) 305 glutanine (gln) genetic variants were statistically associated with adjusted femoral neck hip bmd, adjusted lumbar spine bmd, and adjusted total hip bmd (p values < 0.05). |
2015-12-08 |
2023-08-13 |
Not clear |
| Wei Han, Yun-Dong W. Coarse-Grained Protein Model Coupled with a Coarse-Grained Water Model: Molecular Dynamics Study of Polyalanine-Based Peptides. Journal of chemical theory and computation. vol 3. issue 6. 2015-12-07. PMID:26636208. |
the model was used in the molecular dynamics studies of ac-(ala)6-xaa-(ala)7-nhme, xaa = ala, leu, val, and gly. |
2015-12-07 |
2023-08-13 |
Not clear |
| Wei Han, Yun-Dong W. Coarse-Grained Protein Model Coupled with a Coarse-Grained Water Model: Molecular Dynamics Study of Polyalanine-Based Peptides. Journal of chemical theory and computation. vol 3. issue 6. 2015-12-07. PMID:26636208. |
the calculated s values are 1.18 (ala), 0.84 (leu), 0.30 (val), and <0.02 (gly) at 291 k, in excellent agreement with experimental values (r(2)=0.970). |
2015-12-07 |
2023-08-13 |
Not clear |
| Wei Han, Yun-Dong W. Coarse-Grained Protein Model Coupled with a Coarse-Grained Water Model: Molecular Dynamics Study of Polyalanine-Based Peptides. Journal of chemical theory and computation. vol 3. issue 6. 2015-12-07. PMID:26636208. |
leu and val have lower helical propensities than ala mainly because the larger side chains shield the solvation of helical structures, while gly has a much poorer helical propensity mainly due to the much better solvation for the coil structures than for the helical structures. |
2015-12-07 |
2023-08-13 |
Not clear |
| Adrià Gil, Sílvia Simon, Luis Rodríguez-Santiago, Juan Bertrán, Mariona Sodup. Influence of the Side Chain in the Structure and Fragmentation of Amino Acids Radical Cations. Journal of chemical theory and computation. vol 3. issue 6. 2015-12-07. PMID:26636213. |
the conformational properties of ionized amino acids (gly, ala, ser, cys, asp, gln, phe, tyr, and his) have been theoretically analyzed using the hybrid b3lyp and the hybrid-meta mpwb1k functionals as well as with the post-hartree fock ccsd(t) level of theory. |
2015-12-07 |
2023-08-13 |
Not clear |
| Chompoonuch Wiriyaphan, Hang Xiao, Eric A Decker, Jirawat Yongsawatdigu. Chemical and cellular antioxidative properties of threadfin bream (Nemipterus spp.) surimi byproduct hydrolysates fractionated by ultrafiltration. Food chemistry. vol 167. 2015-12-04. PMID:25148952. |
all fractions were rich in lys, glu/gln, gly, pro, ala, asp/asn, and arg. |
2015-12-04 |
2023-08-13 |
Not clear |
| Hai-Anh Le, Ryan P A Betten. Distributed Multipoles and Energies of Flexible Molecules. Journal of chemical theory and computation. vol 7. issue 4. 2015-11-30. PMID:26606343. |
the molecules considered here are the amino aldehydes, gly and ala, which may be typical smaller fragment molecules in certain molecular energy-based fragmentation schemes. |
2015-11-30 |
2023-08-13 |
Not clear |
| Hai-Anh Le, Ryan P A Betten. Distributed Multipoles and Energies of Flexible Molecules. Journal of chemical theory and computation. vol 7. issue 4. 2015-11-30. PMID:26606343. |
the configuration space covered by the interpolation includes that sampled by the gly and ala peptides in protein crystal structures, i.e., 12 dimensions for gly: 3 torsion angles (φ, ψ, ω), 5 bond lengths, and 4 bond angles and 15 dimensions for ala: 4 torsion angles, 6 bond lengths, and 5 bond angles. |
2015-11-30 |
2023-08-13 |
Not clear |
| Guilherme Volpe Bossa, Alfred Fahr, Tereza Pereira de Souz. Study of pK values and effective dielectric constants of ionizable residues in pentapeptides and in staphylococcal nuclease (SNase) using a mean-field approach. The journal of physical chemistry. B. vol 118. issue 15. 2015-11-16. PMID:24708515. |
the proposed model was applied to the amino acids asp, glu, lys, his, tyr, and cys, and since the results were consistent with experimentally obtained values, the model was extended and applied to computation of pk values of gly and ala pentapeptides and of ionizable residues of the enzyme staphylococcal nuclease (snase). |
2015-11-16 |
2023-08-13 |
Not clear |
| Joseph P Byrne, Jonathan A Kitchen, John E O'Brien, Robert D Peacock, Thorfinnur Gunnlaugsso. Lanthanide directed self-assembly of highly luminescent supramolecular "peptide" bundles from α-amino acid functionalized 2,6-bis(1,2,3-triazol-4-yl)pyridine (btp) ligands. Inorganic chemistry. vol 54. issue 4. 2015-11-02. PMID:25634622. |
a small library of amino acid derivatives of 1, ligands 3, were prepared upon coupling reactions with gly, ala, phe, and trp methyl esters, with a view to introducing biologically relevant and chiral moieties into such ligands. |
2015-11-02 |
2023-08-13 |
Not clear |
| Kyo Kobayashi, Yojiro Maehata, Yasue Okada, Masashi Kusubata, Shunji Hattori, Keisuke Tanaka, Chihiro Miyamoto, Fumihiko Yoshino, Ayaka Yoshida, Fumiaki Tokutomi, Satoko Wada-Takahashi, Tomoko Komatsu, Takero Otsuka, Shun-Suke Takahashi, Masaichi-Chang-Il Le. Medical-grade collagen peptide in injectables provides antioxidant protection. Pharmaceutical development and technology. vol 20. issue 2. 2015-10-30. PMID:24286241. |
the total amount of antioxidant amino acids (gly, hyp, glu, ala, cys, met and his) constituted more than half of the total amino acids in these fractions. |
2015-10-30 |
2023-08-12 |
Not clear |
| Ashley C Gucinski, Michael T Boyne, David A Keir. Modern analytics for naturally derived complex drug substances: NMR and MS tests for protamine sulfate from chum salmon. Analytical and bioanalytical chemistry. vol 407. issue 3. 2015-10-02. PMID:25260409. |
based on these marketplace survey data, nmr acceptance criteria for chum salmon derived protamine sulfate could be based on the absence of aromatic amino acid signals and on ratios of ala βh/arg δh, gly αh/arg δh and arg αh/arg δh integrated areas of 2.4 ± 1%, 9.4 ± 3% and 50 ± 5%, respectively. |
2015-10-02 |
2023-08-13 |
Not clear |
| A Chrissanthopoulos, N Klouras, Ch Ntala, D Sevastos, E Dala. Inhibition of hydroxyapatite formation in the presence of titanocene-amino acid complexes: an experimental and computational study. Journal of materials science. Materials in medicine. vol 26. issue 1. 2015-09-25. PMID:25578695. |
the experiments prove that the presence of [cp2ti(ala)2](2+)2cl(-) and [cp2ti(gly)2](2+)2cl(-) complexes affects drastically the profile formation rate of the hap crystals under biological conditions. |
2015-09-25 |
2023-08-13 |
Not clear |
| Roseanne Norris, Alexey Poyarkov, Martina B O'Keeffe, Richard J FitzGeral. Characterisation of the hydrolytic specificity of Aspergillus niger derived prolyl endoproteinase on bovine β-casein and determination of ACE inhibitory activity. Food chemistry. vol 156. 2015-09-24. PMID:24629934. |
an-pep also had the ability to cleave at the c-terminal side of ala, glu, gly, ser, lys and leu. |
2015-09-24 |
2023-08-12 |
cattle |
| Wei Xia, Wei-fu Peng, Wei Chen, Kun-tai L. Interactive performances of betaine on the metabolic processes of Pseudomonas denitrificans. Journal of industrial microbiology & biotechnology. vol 42. issue 2. 2015-09-14. PMID:25502424. |
by further using a comparative metabolomics approach coupled with intracellular free amino acids analysis for the fermentation processes with betaine addition (10 g/l) or not, it was found that betaine could highly strengthen the formation of some key precursors and intermediates facilitating vitamin b12 biosynthesis, such as δ-aminolevulinic acid (ala, the first precursor of vitamin b12), glutamate (an intermediate of ala via c5 pathway), glycine (an intermediate of ala via c4 pathway), and methionine (directly participating in the methylation reaction involved in vitamin b12 biosynthetic pathway). |
2015-09-14 |
2023-08-13 |
Not clear |
| Emily J Remnant, Craig J Morton, Phillip J Daborn, Christopher Lumb, Ying Ting Yang, Hooi Ling Ng, Michael W Parker, Philip Batterha. The role of Rdl in resistance to phenylpyrazoles in Drosophila melanogaster. Insect biochemistry and molecular biology. vol 54. 2015-08-05. PMID:25193377. |
mutagenesis of these sites and assessment of resistance in vivo in transgenic lines showed that amino acid identity at the ala(301) site influenced resistance levels, with glycine showing greater survival than serine replacement. |
2015-08-05 |
2023-08-13 |
drosophila_melanogaster |
| Romel B Perez, Alexander Tischer, Matthew Auton, Steven T Whitte. Alanine and proline content modulate global sensitivity to discrete perturbations in disordered proteins. Proteins. vol 82. issue 12. 2015-07-20. PMID:25244701. |
using the intrinsically disordered n-terminal region of the p53 protein as an experimental model, a set of proline (pro) and alanine (ala) to glycine (gly) substitution variants were designed to modulate backbone conformational propensities without introducing non-native intramolecular interactions. |
2015-07-20 |
2023-08-13 |
Not clear |
| Sabrina Lechner, Marcel Prax, Birgit Lange, Claudia Huber, Wolfgang Eisenreich, Alexander Herbig, Kay Nieselt, Ralph Bertra. Metabolic and transcriptional activities of Staphylococcus aureus challenged with high-doses of daptomycin. International journal of medical microbiology : IJMM. vol 304. issue 8. 2015-07-16. PMID:24980509. |
isotopologue profiling using fully (13)c-labeled glucose revealed de novo biosynthesis of the amino acids ala, asp, glu, ser, gly and his. |
2015-07-16 |
2023-08-13 |
Not clear |