Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Kris Eldridge, Ronghu Wu, Jonathan K Martens, Terry B McMaho. Gas-phase solvation of protonated amino acids by methanol. The journal of physical chemistry. A. vol 118. issue 49. 2015-07-14. PMID:25402819. |
the enthalpy changes for formation of the clusters gly(meoh)h(+), ala(meoh)h(+), val(meoh)h(+), leu(meoh)h(+), ile(meoh)h(+), and pro(meoh)h(+) have been determined to be -92.0, -83.3, -82.4, -79.5, -78.7, and -73.6 kj mol(-1), respectively. |
2015-07-14 |
2023-08-13 |
Not clear |
Sutha Shobana, Perumal Subramaniam, Liviu Mitu, Jeyaprakash Dharmaraja, Sundaram Arvind Naraya. Synthesis, structural elucidation, biological, antioxidant and nuclease activities of some 5-Fluorouracil-amino acid mixed ligand complexes. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy. vol 134. 2015-07-09. PMID:25022506. |
some biologically active mixed ligand complexes (1-9) have been synthesized from 5-fluorouracil (5-fu; a) and amino acids (b) such as glycine (gly), l-alanine (ala) and l-valine (val) with ni(ii), cu(ii) and zn(ii) ions. |
2015-07-09 |
2023-08-13 |
Not clear |
Benjamin A Anderson, Alex Literati, Borden Ball, Jan Kubelk. Temperature dependence of C-terminal carboxylic group IR absorptions in the amide I' region. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy. vol 134. 2015-07-09. PMID:25036456. |
in this paper we investigate the ir spectra of the asymmetric stretch of α-carboxylic groups for amino acids representing all major types (gly, ala, val, leu, ser, thr, asp, glu, lys, asn, his, trp, pro) as well as the c-terminal groups of three dipeptides (gly-gly, gly-ala, ala-gly) in d₂o at neutral ph. |
2015-07-09 |
2023-08-13 |
human |
Martin Humenik, Michael Magdeburg, Thomas Scheibe. Influence of repeat numbers on self-assembly rates of repetitive recombinant spider silk proteins. Journal of structural biology. vol 186. issue 3. 2015-07-02. PMID:24657229. |
the c-module comprises 35 amino acids rich in glycine and proline residues (in gpgxy repeats) and one polyalanine stretch (ala)8. |
2015-07-02 |
2023-08-12 |
spider |
Vishnu Menon, Mala Ra. Interactions of a low molecular weight inhibitor from Streptomyces sp. MBR04 with human cathepsin D: implications in mechanism of inactivation. Applied biochemistry and biotechnology. vol 174. issue 5. 2015-06-23. PMID:25141983. |
the mr of the inhibitor was 1,078 da as determined by maldi-tof, and the amino acid analysis showed the presence of asp, asp, gly, ala, lys, leu, tyr, trp residues. |
2015-06-23 |
2023-08-13 |
human |
Jeyaprakash Dharmaraja, Paramasivam Subbaraj, Thirugnanasamy Esakkidurai, Sutha Shobana, Saravanan Raj. Complexation equilibria and coordination aspects of Zn(II) complexes contain 2-aminobenzamide and some bioactive amino acid mixed ligands: pH-metric, spectroscopic and thermodynamic studies. Acta chimica Slovenica. vol 61. issue 4. 2015-05-29. PMID:25551720. |
mixed ligand complexation of 2-aminobenzamide (2ab) as ligand [l] with zn(ii) in the presence of some bio-relevant amino acid constituents like glycine (gly), l-alanine (ala), l-valine (val) and l-phenylalanine (phe) as ligand [b] have been investigated using ph-metric measurements with a combined ph electrode at different temperatures (300, 310, 320 and 330 ± 0.1 k) in 50% (v/v) ethanol-water mixture containing i = 0.15 m naclo(4) as supporting electrolyte. |
2015-05-29 |
2023-08-13 |
Not clear |
Meng-Yue Zhang, Jun Xie, Tian-Yuan Zhang, Huan Xu, Juan Cheng, Shan-Hui Li, Wen-Jun Li, Yi-Xuan Zhan. Sinomonas notoginsengisoli sp. nov., isolated from the rhizosphere of Panax notoginseng. Antonie van Leeuwenhoek. vol 106. issue 4. 2015-05-15. PMID:25103948. |
the major cell-wall amino acids were identified as lys, ala, glu, gly and ser. |
2015-05-15 |
2023-08-13 |
Not clear |
Jörg Willenborg, Claudia Huber, Anna Koczula, Birgit Lange, Wolfgang Eisenreich, Peter Valentin-Weigand, Ralph Goeth. Characterization of the pivotal carbon metabolism of Streptococcus suis serotype 2 under ex vivo and chemically defined in vitro conditions by isotopologue profiling. The Journal of biological chemistry. vol 290. issue 9. 2015-05-11. PMID:25575595. |
de novo biosynthesis was shown for ala, asp, ser, and thr at high rates and for gly, lys, phe, tyr, and val at moderate or low rates, respectively. |
2015-05-11 |
2023-08-13 |
Not clear |
Tohru Fujiwara, Koji Okamoto, Ryoyu Niikuni, Kiwamu Takahashi, Yoko Okitsu, Noriko Fukuhara, Yasushi Onishi, Kenichi Ishizawa, Ryo Ichinohasama, Yukio Nakamura, Motowo Nakajima, Tohru Tanaka, Hideo Hariga. Effect of 5-aminolevulinic acid on erythropoiesis: a preclinical in vitro characterization for the treatment of congenital sideroblastic anemia. Biochemical and biophysical research communications. vol 454. issue 1. 2015-05-01. PMID:25450364. |
alas2 is a mitochondrial enzyme, which utilizes glycine and succinyl-coa to form 5-aminolevulinic acid (ala), a crucial precursor in heme synthesis. |
2015-05-01 |
2023-08-13 |
human |
Ryousuke Ito, Yukari Masukawa, Chika Nakada, Kanako Amari, Chiaki Nakano, Tsutomu Hoshin. β-Amyrin synthase from Euphorbia tirucalli. Steric bulk, not the π-electrons of Phe, at position 474 has a key role in affording the correct folding of the substrate to complete the normal polycyclization cascade. Organic & biomolecular chemistry. vol 12. issue 23. 2015-04-17. PMID:24695673. |
nine site-specific variants with gly, ala, val, leu, met, tyr, trp, his, and thr were constructed. |
2015-04-17 |
2023-08-13 |
Not clear |
Ryousuke Ito, Yukari Masukawa, Chika Nakada, Kanako Amari, Chiaki Nakano, Tsutomu Hoshin. β-Amyrin synthase from Euphorbia tirucalli. Steric bulk, not the π-electrons of Phe, at position 474 has a key role in affording the correct folding of the substrate to complete the normal polycyclization cascade. Organic & biomolecular chemistry. vol 12. issue 23. 2015-04-17. PMID:24695673. |
the gly and ala mutants produced significantly larger amounts of the bicyclic products and a decreased amount of β-amyrin, indicating that the f474 residue was located near the b-ring formation site. |
2015-04-17 |
2023-08-13 |
Not clear |
Qingquan Ma, Wenjing Jiao, Yinfeng Lv, Na Dong, Xin Zhu, Anshan Sha. Structure-function relationship of Val/Arg-rich peptides: effects of net charge and pro on activity. Chemical biology & drug design. vol 84. issue 3. 2015-03-31. PMID:24649883. |
replacement of gly with ala or pro led to the decrease in antimicrobial activity. |
2015-03-31 |
2023-08-12 |
Not clear |
Qingquan Ma, Wenjing Jiao, Yinfeng Lv, Na Dong, Xin Zhu, Anshan Sha. Structure-function relationship of Val/Arg-rich peptides: effects of net charge and pro on activity. Chemical biology & drug design. vol 84. issue 3. 2015-03-31. PMID:24649883. |
the substitution of gly with ala retained its hemolytic activity, while the substitution with pro significantly decreased the toxicity, suggesting positive effect of pro on hemolytic activity. |
2015-03-31 |
2023-08-12 |
Not clear |
Juanjuan Tan, Jinfeng Huang, Yibing Huang, Yuxin Che. Effects of single amino acid substitution on the biophysical properties and biological activities of an amphipathic α-helical antibacterial peptide against Gram-negative bacteria. Molecules (Basel, Switzerland). vol 19. issue 8. 2015-03-31. PMID:25061725. |
six amino acids (lys, glu, gly, ser, ala, and leu) were individually used to substitute the original hydrophobic valine at the selected sixteenth location on the non-polar face of v13k. |
2015-03-31 |
2023-08-13 |
Not clear |
Murugesan Chandrasekaran, Raman Chandrasekar, Tongmin Sa, Muthukrishnan Sathiyabam. Serine protease identification (in vitro) and molecular structure predictions (in silico) from a phytopathogenic fungus, Alternaria solani. Journal of basic microbiology. vol 54 Suppl 1. 2015-03-30. PMID:24122785. |
also, calcium ion (ca(2+)) is coordinated by the carboxyl groups of lys(84), ile(85), lys(86), asp(87), phe(88), ala(89), ala(90) (k84-a90) for first ca(2+) binding site and carbonyl oxygen atom of lys(244), gly(245), arg(246), thr(247), lys(248), lys(249), and ala(250) (k244-a250), for second ca(2+) binding site. |
2015-03-30 |
2023-08-12 |
Not clear |
Hwei-Ming Peng, Jiayan Liu, Sarah E Forsberg, Hong T Tran, Sean M Anderson, Richard J Auchu. Catalytically relevant electrostatic interactions of cytochrome P450c17 (CYP17A1) and cytochrome b5. The Journal of biological chemistry. vol 289. issue 49. 2015-03-03. PMID:25315771. |
substitution of ala, gly, cys, or gln for these two glutamic acid residues abrogated all capacity to stimulate 17,20-lyase activity. |
2015-03-03 |
2023-08-13 |
Not clear |
Bo-Keun Ha, Hyun-Jee Kim, Vijayanand Velusamy, Tri D Vuong, Henry T Nguyen, J Grover Shannon, Jeong-Dong Le. Identification of quantitative trait loci controlling linolenic acid concentration in PI483463 (Glycine soja). TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik. vol 127. issue 7. 2015-02-21. PMID:24794978. |
some wild soybean (glycine soja) genotypes are high in ala. |
2015-02-21 |
2023-08-13 |
human |
Wei Zheng, Chen Zhang, Michelle Hanlon, Jishou Ruan, Jianzhao Ga. An ensemble method for prediction of conformational B-cell epitopes from antigen sequences. Computational biology and chemistry. vol 49. 2015-02-19. PMID:24607818. |
in a bound dataset, asn (n), glu (e), gly (g), lys (k), ser (s), and thr (t) are preferred in epitope regions, while ala (a), leu (l) and val (v) are preferred in non-epitope regions. |
2015-02-19 |
2023-08-12 |
Not clear |
Alexandre Beautrait, Kevin R Michalski, Thomas S Lopez, Katelynn M Mannix, Devin J McDonald, Amber R Cutter, Christopher B Medina, Aaron M Hebert, Charnelle J Francis, Michel Bouvier, John J G Tesmer, Rachel Sterne-Mar. Mapping the putative G protein-coupled receptor (GPCR) docking site on GPCR kinase 2: insights from intact cell phosphorylation and recruitment assays. The Journal of biological chemistry. vol 289. issue 36. 2015-01-28. PMID:25049229. |
we suggest that a surface of grk2, including leu(4), val(7), leu(8), val(11), and ser(12), directly interacts with receptors, whereas residues such as asp(10), tyr(13), ala(16), met(17), gly(475), val(477), and ile(485) are more important for kinase domain closure and activation. |
2015-01-28 |
2023-08-13 |
Not clear |
M Yamakado, T Tanaka, K Nagao, Y Ishizaka, T Mitushima, M Tani, A Toda, E Toda, M Okada, H Miyano, H Yamamot. Plasma amino acid profile is associated with visceral fat accumulation in obese Japanese subjects. Clinical obesity. vol 2. issue 1-2. 2015-01-15. PMID:25586045. |
what this study adds • a specific formula incorporating six amino acid values (ala, gly, glu, trp, tyr and branched-chain amino acid) was developed for discrimination of subjects with high visceral fat area by multivariate logistic regression analyses. |
2015-01-15 |
2023-08-13 |
human |