| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Prashen Chelikani, Viktor Hornak, Markus Eilers, Phillip J Reeves, Steven O Smith, Uttam L RajBhandary, H Gobind Khoran. Role of group-conserved residues in the helical core of beta2-adrenergic receptor. Proceedings of the National Academy of Sciences of the United States of America. vol 104. issue 17. 2007-06-06. PMID:17438264. |
recently, a second set of sites in the transmembrane helices has been identified in which amino acids with small side chains, such as gly, ala, ser, thr, and cys, are highly conserved (>90%) when considered as a group. |
2007-06-06 |
2023-08-12 |
Not clear |
| Takuya Kanno, Michiko Kitano, Rika Kato, Akira Omori, Yaeta Endo, Yuzuru Tozaw. Sequence specificity and efficiency of protein N-terminal methionine elimination in wheat-embryo cell-free system. Protein expression and purification. vol 52. issue 1. 2007-05-09. PMID:17123829. |
in the case of male, the cleavage was efficient when the penultimate residue was ala, cys, gly, pro, ser or thr. |
2007-05-09 |
2023-08-12 |
Not clear |
| Takuya Kanno, Michiko Kitano, Rika Kato, Akira Omori, Yaeta Endo, Yuzuru Tozaw. Sequence specificity and efficiency of protein N-terminal methionine elimination in wheat-embryo cell-free system. Protein expression and purification. vol 52. issue 1. 2007-05-09. PMID:17123829. |
we also confirmed that substitution of the antepenultimate residue in male to pro drastically reduced the efficiency of n-met cleavage when the penultimate residue was ala, gly, pro, ser or thr, indicating inhibitory effects of antepenultimate residue pro on n-met elimination. |
2007-05-09 |
2023-08-12 |
Not clear |
| Yen-Peng Ho, Ming-Wei Yang, Li-Ting Chen, Yu-Chuan Yan. Relative calcium-binding strengths of amino acids determined using the kinetic method. Rapid communications in mass spectrometry : RCM. vol 21. issue 6. 2007-05-09. PMID:17315289. |
the relative ca(2+)-binding strengths of the alpha-amino acid complexes follow the order cys < ser < thr < ile < leu < val < gly < ala < pro < phe < met < tyr < asn < his < gln < trp < lys < arg. |
2007-05-09 |
2023-08-12 |
Not clear |
| Sung-Ah Lee, Yu Kyoung Kim, Shin Saeng Lim, Wan Long Zhu, Hyunsook Ko, Song Yub Shin, Kyung-Soo Hahm, Yangmee Ki. Solution structure and cell selectivity of piscidin 1 and its analogues. Biochemistry. vol 46. issue 12. 2007-05-09. PMID:17328560. |
in the present study, to develop novel antibiotic peptides with selectivity for bacterial cells, we examined the effect of substituting two glycine residues, gly8 and gly13, with ala or pro on this peptide's structure and biological activities. |
2007-05-09 |
2023-08-12 |
Not clear |
| Sung-Ah Lee, Yu Kyoung Kim, Shin Saeng Lim, Wan Long Zhu, Hyunsook Ko, Song Yub Shin, Kyung-Soo Hahm, Yangmee Ki. Solution structure and cell selectivity of piscidin 1 and its analogues. Biochemistry. vol 46. issue 12. 2007-05-09. PMID:17328560. |
the bacterial cell selectivity of the peptides decreased in the following order: gly-->pro analogues > gly-->pro/ala analogues > pis-1 > gly-->ala analogues. |
2007-05-09 |
2023-08-12 |
Not clear |
| Zheng-Yu Wang, Hiroaki Suzuki, Masayuki Kobayashi, Tsunenori Nozaw. Solution structure of the Rhodobacter sphaeroides PufX membrane protein: implications for the quinone exchange and protein-protein interactions. Biochemistry. vol 46. issue 12. 2007-05-09. PMID:17335288. |
a short segment (lys28-gly35) rich in gly and ala residues revealed a relatively fast exchange between the backbone amide protons and deuteriums in the hydroxyl groups of the solvent, indicating that the backbone of this segment is more easily accessible to the surrounding solvent molecules compared to those of its neighboring portions. |
2007-05-09 |
2023-08-12 |
Not clear |
| Saritha Baddam, Bruce E Bowle. Tuning the rate and pH accessibility of a conformational electron transfer gate. Inorganic chemistry. vol 45. issue 16. 2007-05-04. PMID:16878944. |
to adjust the ph accessibility of the slow lys 73-heme et gate, we convert the buried side chain asn 52 to gly and also mutate lys 79 to ala to simplify et gating (a79g52 variant). |
2007-05-04 |
2023-08-12 |
Not clear |
| Sarah K Holt, Mary Anne Rossing, Kathleen E Malone, Stephen M Schwartz, Noel S Weiss, Chu Che. Ovarian cancer risk and polymorphisms involved in estrogen catabolism. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. vol 16. issue 3. 2007-05-03. PMID:17372243. |
subjects were interviewed and genotyped for cyp1a1 m1, m2, m3, and m4; cyp1b1 arg(48)gly, ala(119)ser, val(432)leu, and asn(453)ser; comt val(158)met; ugt1a1 a(ta)ntaa; and sult1a1 arg(213)his polymorphisms. |
2007-05-03 |
2023-08-12 |
human |
| Katja Kristan, Jure Stojan, Jerzy Adamski, Tea Lanisnik Rizne. Rational design of novel mutants of fungal 17beta-hydroxysteroid dehydrogenase. Journal of biotechnology. vol 129. issue 1. 2007-05-02. PMID:17196285. |
replacement of val161 and tyr212 in the substrate-binding region by gly and ala, respectively, increased the initial rates for the conversion of androstenedione to testosterone. |
2007-05-02 |
2023-08-12 |
Not clear |
| Svetlana R Amirova, Juri V Milchevsky, Ivan V Filatov, Natalia G Esipova, Vladimir G Tumanya. Study and prediction of secondary structure for membrane proteins. Journal of biomolecular structure & dynamics. vol 24. issue 4. 2007-04-24. PMID:17206856. |
these protein properties include hydrophobic properties of amino acid residues, presence of gly, ala and val amino acids, and the location of protein chain end. |
2007-04-24 |
2023-08-12 |
Not clear |
| Guozhong Xu, Mark R Chanc. Radiolytic modification and reactivity of amino acid residues serving as structural probes for protein footprinting. Analytical chemistry. vol 77. issue 14. 2007-04-19. PMID:16013872. |
a reactivity order of amino acid side chains was obtained as cys > met > trp > tyr > phe > cystine > his > leu, ile > arg, lys, val > ser, thr, pro > gln, glu > asp, asn > ala > gly. |
2007-04-19 |
2023-08-12 |
Not clear |
| Guozhong Xu, Mark R Chanc. Radiolytic modification and reactivity of amino acid residues serving as structural probes for protein footprinting. Analytical chemistry. vol 77. issue 14. 2007-04-19. PMID:16013872. |
ala and gly are far too unreactive to be useful probes in typical experiments and asp and asn are unlikely to be useful as well. |
2007-04-19 |
2023-08-12 |
Not clear |
| Kathryn A Scott, Darwin O V Alonso, Satoshi Sato, Alan R Fersht, Valerie Dagget. Conformational entropy of alanine versus glycine in protein denatured states. Proceedings of the National Academy of Sciences of the United States of America. vol 104. issue 8. 2007-04-12. PMID:17307875. |
we have performed all-atom molecular dynamics simulations with explicit solvent and exhaustive sampling of model peptides to address the backbone conformational entropy difference between ala and gly in the denatured state. |
2007-04-12 |
2023-08-12 |
Not clear |
| Kathryn A Scott, Darwin O V Alonso, Satoshi Sato, Alan R Fersht, Valerie Dagget. Conformational entropy of alanine versus glycine in protein denatured states. Proceedings of the National Academy of Sciences of the United States of America. vol 104. issue 8. 2007-04-12. PMID:17307875. |
the mutation of ala to gly leads to an increase in conformational entropy equivalent to approximately 0.4 kcal.mol(-1) in a fully flexible denatured, that is, unfolded, state. |
2007-04-12 |
2023-08-12 |
Not clear |
| Kathryn A Scott, Darwin O V Alonso, Satoshi Sato, Alan R Fersht, Valerie Dagget. Conformational entropy of alanine versus glycine in protein denatured states. Proceedings of the National Academy of Sciences of the United States of America. vol 104. issue 8. 2007-04-12. PMID:17307875. |
the helix-stabilizing propensity of ala relative to gly thus mainly results from more favorable interactions of ala in the folded helical structure. |
2007-04-12 |
2023-08-12 |
Not clear |
| Kathryn A Scott, Darwin O V Alonso, Satoshi Sato, Alan R Fersht, Valerie Dagget. Conformational entropy of alanine versus glycine in protein denatured states. Proceedings of the National Academy of Sciences of the United States of America. vol 104. issue 8. 2007-04-12. PMID:17307875. |
the small difference in energetics in the denatured states means that the phi-values derived from ala --> gly scanning of helices are a very good measure of the extent of formation of structure in proteins with little residual structure in the denatured state. |
2007-04-12 |
2023-08-12 |
Not clear |
| Frédéric Frottin, Aude Martinez, Philippe Peynot, Sanghamitra Mitra, Richard C Holz, Carmela Giglione, Thierry Meinne. The proteomics of N-terminal methionine cleavage. Molecular & cellular proteomics : MCP. vol 5. issue 12. 2007-04-10. PMID:16963780. |
peptides with val or thr at p1' were much less efficiently cleaved than those with ala, cys, gly, pro, or ser in this position. |
2007-04-10 |
2023-08-12 |
Not clear |
| Masayoshi Nagamine, Miki Takahara, Kan Kishibe, Toshihiro Nagato, Hideyuki Ishii, Nobuyuki Bandoh, Takeshi Ogino, Yasuaki Harabuch. Sequence variations of Epstein-Barr virus LMP1 gene in nasal NK/T-cell lymphoma. Virus genes. vol 34. issue 1. 2007-04-09. PMID:16917737. |
in the epitopes allvlysfa (codon 51-59), vlfifgcll (codon 110-118) and wlllflail (codon 173-181), several patients showed novel amino acid changes at codon 59 (ala to gly), 110 (val to leu) and 174 (leu to ile), respectively. |
2007-04-09 |
2023-08-12 |
Not clear |
| b' Jarom\\xc3\\xadr Vinkl\\xc3\\xa1rek, Hana Pal\\xc3\\xa1ckov\\xc3\\xa1, Jan Honz\\xc3\\xadcek, Jana Holubov\\xc3\\xa1, Michal Holcapek, Ivana C\\xc3\\xadsarov\\xc3\\xa. Investigation of vanadocene(IV) alpha-amino acid complexes: synthesis, structure, and behavior in physiological solutions, human plasma, and blood. Inorganic chemistry. vol 45. issue 5. 2007-03-29. PMID:16499378.' |
sixteen vanadocene amino acid complexes [cp2v(aa)][x] (aa = gly, ala, val, leu, ile, phe, his, and trp; x = cl, pf6) were prepared and characterized on the basis of spectral measurements (epr, ms, ir, raman). |
2007-03-29 |
2023-08-12 |
human |